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    HAIR OBSERVATION METHOD, PHASE CONTRAST MICROSCOPE SYSTEM, AND PREPARATION
    1.
    发明申请
    HAIR OBSERVATION METHOD, PHASE CONTRAST MICROSCOPE SYSTEM, AND PREPARATION 有权

    公开(公告)号：US20210102890A1

    公开(公告)日：2021-04-08

    申请号：US16608012

    申请日：2018-04-18

    Applicant: RIKEN ,  ORGAN TECHNOLOGIES, INC. ,  KYOCERA Corporation

    Inventor： Takashi TSUJI ,  Koh-ei TOYOSHIMA ,  Kazuto MIYAZAKI ,  Takashi SAOTOME

    IPC: G01N21/27 ,  G01N21/359 ,  G02B21/12 ,  G02B21/14 ,  G02B21/34

    Abstract: Provided are a hair observation method, a phase contrast microscope system, and a preparation. The hair observation method includes capturing an infrared image of the hair using an image sensor that is capable of detecting infrared light. A phase contrast microscope system includes: a stage having a sample placed thereon; an infrared light irradiation source for irradiating infrared light to the sample placed on the stage; an image sensor that is capable of detecting infrared light and configured to capture an infrared image of the sample; and a display apparatus configured to display the infrared image captured by the image sensor. The preparation includes a microscope glass and a plurality of hair pieces that are obtained by cutting one hair and arranged on the microscope glass in a manner parallel with one another from one end to another end in a cutting order.

    Hair observation method, phase contrast microscope system, and preparation
    3.
    发明授权
    Hair observation method, phase contrast microscope system, and preparation 有权

    公开(公告)号：US11209348B2

    公开(公告)日：2021-12-28

    申请号：US16608012

    申请日：2018-04-18

    Applicant: RIKEN ,  ORGAN TECHNOLOGIES, INC. ,  KYOCERA Corporation

    Inventor： Takashi Tsuji ,  Koh-ei Toyoshima ,  Kazuto Miyazaki ,  Takashi Saotome

    IPC: G01N21/27 ,  G01N21/359 ,  G02B21/12 ,  G02B21/14 ,  G02B21/34

    Abstract: Provided are a hair observation method, a phase contrast microscope system, and a preparation. The hair observation method includes capturing an infrared image of the hair using an image sensor that is capable of detecting infrared light. A phase contrast microscope system includes: a stage having a sample placed thereon; an infrared light irradiation source for irradiating infrared light to the sample placed on the stage; an image sensor that is capable of detecting infrared light and configured to capture an infrared image of the sample; and a display apparatus configured to display the infrared image captured by the image sensor. The preparation includes a microscope glass and a plurality of hair pieces that are obtained by cutting one hair and arranged on the microscope glass in a manner parallel with one another from one end to another end in a cutting order.

    Method for maintaining organ or tissue for transplantation use for long period
    6.
    发明授权
    Method for maintaining organ or tissue for transplantation use for long period 有权

    公开(公告)号：US09877474B2

    公开(公告)日：2018-01-30

    申请号：US14426011

    申请日：2013-08-29

    Applicant: Organ Technologies, Inc.

    Inventor： Takashi Tsuji ,  Masamitsu Oshima

    IPC: A01N1/02

    CPC classification number: A01N1/0226 ,  A01N1/0247

    Abstract: The object of the present invention is to provide a technology that enables long-term preservation while maintaining the function of an organ or tissue for transplantation. A further object is utilizing this technology to provide a technology for suppressing tissue disorder accompanying warm ischemia and reperfusion as well as restoring an organ from a cardiac arrest donor to a level compatible for transplantation. A method that employs perfusion by a perfusate etc. is provided, comprising each of the following steps of: (a) connecting a perfusate instream cannula for streaming said perfusate into said “organ or tissue,” (b) connecting a perfusate outstream cannula for streaming said perfusate out from said “organ or tissue,” and (c) perfusing a perfusate comprising an oxygen carrier and a blood coagulation inhibitor into said organ or tissue.

    METHOD FOR MAINTAINING ORGAN OR TISSUE FOR TRANSPLANTATION USE FOR LONG PERIOD
    7.
    发明申请
    METHOD FOR MAINTAINING ORGAN OR TISSUE FOR TRANSPLANTATION USE FOR LONG PERIOD 审中-公开
    维持长期运输使用的组织或组织的方法

    公开(公告)号：US20150289499A1

    公开(公告)日：2015-10-15

    申请号：US14426011

    申请日：2013-08-29

    Applicant: Organ Technologies, Inc.

    Inventor： Takashi Tsuji ,  Masamitsu Oshima

    IPC: A01N1/02

    CPC classification number: A01N1/0226 ,  A01N1/0247

    Abstract: The object of the present invention is to provide a technology that enables long-term preservation while maintaining the function of an organ or tissue for transplantation. A further object is utilizing this technology to provide a technology for suppressing tissue disorder accompanying warm ischemia and reperfusion as well as restoring an organ from a cardiac arrest donor to a level compatible for transplantation. A long-term maintenance method of a mammalian organ or tissue for transplantation that employs perfusion by a perfusate etc. is provided, comprising each of the following steps of: (a) connecting a perfusate instream cannula for streaming said perfusate into said “organ or tissue,” (b) connecting a perfusate outstream cannula for streaming said perfusate out from said “organ or tissue,” and (c) perfusing a perfusate comprising an oxygen carrier and a blood coagulation inhibitor into said organ or tissue.

    Abstract translation: 本发明的目的是提供一种能够在保持用于移植的器官或组织的功能的同时长期保存的技术。 另一个目的是利用该技术来提供一种抑制伴随热缺血和再灌注的组织病变以及将器官从心脏骤停供体恢复到与移植相容的水平的技术。 提供了哺乳动物器官或组织用于通过灌注液等灌注的哺乳动物器官或组织的长期维持方法，其包括以下步骤中的每一个：（a）连接灌注液插管，用于将所述灌注液流入所述“器官或 （b）连接用于将所述灌洗液从所述“器官或组织”流出的灌注液外流套管，和（c）将包含氧载体和凝血抑制剂的灌注液灌注到所述器官或组织中。

    DENTAL IMPLANT AND METHOD FOR PRODUCING SAME
    8.
    发明申请
    DENTAL IMPLANT AND METHOD FOR PRODUCING SAME 有权
    牙植入物及其生产方法

    公开(公告)号：US20140356797A1

    公开(公告)日：2014-12-04

    申请号：US14375715

    申请日：2013-01-28

    Applicant: Organ Technologies, Inc.

    Inventor： Takashi Tsuji ,  Masamitsu Oshima

    IPC: A61C8/00 ,  A61K6/033 ,  A61D5/00

    CPC classification number: A61C8/0013 ,  A61D5/00 ,  A61K6/0038 ,  A61K6/0044 ,  A61K6/0085 ,  A61K6/033 ,  A61L27/32 ,  A61L27/34 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3821 ,  A61L27/3834 ,  A61L27/3865 ,  A61L2430/12 ,  C08L89/06

    Abstract: The purpose of the present invention is to provide a dental implant which enables the formation of a functional periodontal tissue around the implant after the implantation of the implant. The dental implant according to the present invention is characterized in that a cell mass originated from a tooth germ tissue or a periodontal ligament tissue is placed on the surface of the implant and the surface of the implant on which the cell mass is to be placed is the whole or a part of a surface that is surrounded by an alveolar bone of a recipient during the implantation of the implant.

    Abstract translation: 本发明的目的是提供一种牙植入物，其能够在植入物植入之后在植入物周围形成功能性牙周组织。 根据本发明的牙科植入物的特征在于，源自牙胚组织或牙周韧带组织的细胞质量被放置在植入物的表面上，并且待放置细胞块的植入物的表面是 在植入物植入期间由受体的牙槽骨包围的表面的整个或一部分。

    Perfusion Culture Method and Perfusion Culture Device for Organ or Tissue
    9.
    发明申请
    Perfusion Culture Method and Perfusion Culture Device for Organ or Tissue 审中-公开
    灌注培养方法和器官或组织灌注培养装置

    公开(公告)号：US20140256027A1

    公开(公告)日：2014-09-11

    申请号：US14283971

    申请日：2014-05-21

    Applicant: Organ Technologies, Inc.

    Inventor： Takashi Tsuji ,  Kazuhisa Nakao

    IPC: A01N1/02

    CPC classification number: A01N1/0247 ,  C12M21/08 ,  C12M29/10

    Abstract: Disclosed are a perfusion culture method and a perfusion culture device whereby a perfusate can be delivered to all parts of an organ or tissue so that the organ or tissue can be preserved while sufficiently maintaining the function thereof. Specifically disclosed is a method for perfusion culture of an organ or tissue removed from a mammal, said organ or tissue having been removed together with a second organ or tissue connected to the aforesaid organ or tissue in vivo, which comprises a step for fixing said second organ or tissue so as to hang the aforesaid organ or tissue and a step for perfusing blood vessels in the aforesaid organ or tissue with a perfusate.

    Abstract translation: 公开了一种灌注培养方法和灌注培养装置，其中灌注液可以递送到器官或组织的所有部分，使得可以在充分保持其功能的同时保存器官或组织。 具体公开了一种用于从哺乳动物，所述器官或组织移除的器官或组织的灌注培养的方法，所述器官或组织与连接到所述前述器官或组织的体内的第二器官或组织一起被去除，其包括用于固定所述第二 器官或组织，以悬挂上述器官或组织，以及用灌注液灌注前述器官或组织中的血管的步骤。

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