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    Method For Producing Multiple Emulsions That Are Stable In Storage
    2.
    发明申请
    Method For Producing Multiple Emulsions That Are Stable In Storage 失效
    在储存中产生稳定的多种乳液的方法

    公开(公告)号：US20070253986A1

    公开(公告)日：2007-11-01

    申请号：US10578329

    申请日：2004-10-29

    申请人： Olaf Stange ,  Martina Mutter ,  Tanja Oswald ,  Mark Schmitz

    发明人： Olaf Stange ,  Martina Mutter ,  Tanja Oswald ,  Mark Schmitz

    IPC分类号： A61K9/113 ,  A61K39/00 ,  A61K39/02 ,  A61P37/00 ,  A61K39/12

    CPC分类号： A61K9/113 ,  Y10S514/937 ,  Y10S514/939

    摘要： A process is described for the preparation of storage-stable, multiple emulsions of the water/oil/water (W/O/W) type which comprise one or more active ingredients. The process comprises the steps a) stirring the active ingredient into an aqueous phase, b) emulsifying the aqueous phase by passing the aqueous phase through a large-pored, porous membrane into an oil phase, c) phase inversion of the emulsion from b), by cooling the mixture at a cooling rate of at least 0.3 K/min, where an emulsifier is added either to the aqueous phase in a) or to the oil phase in b) or to both phases.

    摘要翻译： 描述了制备包含一种或多种活性成分的水/油/水（W / O / W）类型的储存稳定的多重乳液的方法。 该方法包括以下步骤：a）将活性成分搅拌成水相，b）通过将水相通过大孔多孔膜进入油相中乳化水相，c）从b）相转化乳液， 通过以至少0.3K / min的冷却速度冷却混合物，其中将乳化剂加入a）中的水相或b）或两相中的油相中。

    Method for producing multiple emulsions that are stable in storage
    4.
    发明授权
    Method for producing multiple emulsions that are stable in storage 失效
    用于生产储存稳定的多重乳液的方法

    公开(公告)号：US07943154B2

    公开(公告)日：2011-05-17

    申请号：US10578329

    申请日：2004-10-29

    申请人： Olaf Stange ,  Martina Mutter ,  Tanja Oswald ,  Mark Schmitz

    发明人： Olaf Stange ,  Martina Mutter ,  Tanja Oswald ,  Mark Schmitz

    IPC分类号： A61K9/113 ,  A61K39/00 ,  C09K3/00

    CPC分类号： A61K9/113 ,  Y10S514/937 ,  Y10S514/939

    摘要： A process is described for the preparation of storage-stable, multiple emulsions of the water/oil/water (W/O/W) type which comprise one or more active ingredients.The process comprises the steps a) stirring the active ingredient into an aqueous phase, b) emulsifying the aqueous phase by passing the aqueous phase through a large-pored, porous membrane into an oil phase, c) phase inversion of the emulsion from b), by cooling the mixture at a cooling rate of at least 0.3 K/min, where an emulsifier is added either to the aqueous phase in a) or to the oil phase in b) or to both phases.

    摘要翻译： 描述了制备包含一种或多种活性成分的水/油/水（W / O / W）类型的储存稳定的多重乳液的方法。 该方法包括以下步骤：a）将活性成分搅拌成水相，b）通过将水相通过大孔多孔膜进入油相中乳化水相，c）从b）相转化乳液， 通过以至少0.3K / min的冷却速度冷却混合物，其中将乳化剂加入a）中的水相或b）或两相中的油相中。