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1.发明授权公开(公告)号：US11738001B2
公开(公告)日：2023-08-29
申请号：US15733131
申请日：2018-11-26
IPC分类号： A61K31/343 , A61P3/10 , A61K31/121 , A61K36/28
CPC分类号： A61K31/343 , A61K31/121 , A61K36/28 , A61P3/10 , A61K2236/331
摘要： The invention relates to pharmaceutical compositions comprising combinations of flavonoids that may be used to treat and/or prevent diabetes and associated diseases, conditions and/or disorders. The invention also relates to methods of treating diabetes and associated diseases, conditions and/or disorders using the pharmaceutical compositions.
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公开(公告)号：US09784749B2
公开(公告)日：2017-10-10
申请号：US15036748
申请日：2014-11-14
CPC分类号： G01N33/6893 , C07K14/4716 , C07K16/18 , C07K2317/33 , C07K2317/34 , G01N33/6887 , G01N2333/4712 , G01N2800/32 , G01N2800/50 , G01N2800/52
摘要： The present invention relates generally to assays, methods and kits for the prognosis and/or diagnosis of cardiac disorders. The present invention also provides, for example, binding agents to a novel class of circulating cardiac troponin T upstream open reading frame (TnTuORF) peptide biomarkers for use in predicting or diagnosing a cardiac disorder other than myocardial infarction or unstable angina. In addition, the binding agents of the present invention may be used to enhance the sensitivity and false positive performance of cardiac troponins in the prognosis and diagnosis of myocardial infarction.
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公开(公告)号：US20160258967A1
公开(公告)日：2016-09-08
申请号：US15062185
申请日：2016-03-06
发明人： Christopher Joseph PEMBERTON , Arthur Mark RICHARDS , Michael Gary NICHOLLS , Timothy Grant YANDLE
IPC分类号： G01N33/74
CPC分类号： G01N33/74 , C07K14/58 , C07K16/26 , G01N33/6887 , G01N33/6893 , G01N2333/58 , G01N2800/32 , G01N2800/324 , G01N2800/52
摘要： The invention provides methods for predicting, diagnosing or monitoring acute cardiac disorders, cardiac transplant rejection, or distinguishing acute cardiac disorders from pulmonary disorders, by measuring BNP signal peptide levels in a sample taken from a subject shortly after onset of, or presentation with the disorder or transplant rejection.
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公开(公告)号：US20240093297A1
公开(公告)日：2024-03-21
申请号：US18006566
申请日：2021-07-23
IPC分类号： C12Q1/6883 , C12Q1/6851
CPC分类号： C12Q1/6883 , C12Q1/6851 , C12Q2600/112 , C12Q2600/158 , C12Q2600/178
摘要： Analysis of microRNA (miRNA) signatures to determine or predict stages of cognitive impairment and likelihood of Alzheimer's disease in an individual.
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公开(公告)号：US20220249275A1
公开(公告)日：2022-08-11
申请号：US17628527
申请日：2020-07-17
申请人： Michael Lynn STITELY , Gwynneth Helen PATERSON , Stuart MAY , Robert John SMITH , Greta Isabella SAGGUS , Otago Innovation Limited
发明人： Michael Lynn STITELY , Gwynneth Helen PATERSON , Stuart MAY , Robert John SMITH , Greta Isabella SAGGUS
摘要： An insertion device for an IUD. The insertion device comprises an introducer having an elongate hollow body and a first end and a second end, the hollow body defining an elongate passageway extending from the first end to the second end and defining openings at the first end and the second end, and a pusher provided or configured to be provided inside the elongate passageway such that the pusher is movable through or along the passageway. The passageway is sized to accommodate an IUD such that the IUD is slidable along the passageway. Further, the second end of the introducer that abuts the fundus of the uterus in use is configured to have an increased surface area relative to prior art devices so as to reduce the risk of injury, including perforation of the uterus.
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6.发明申请公开(公告)号：US20200289453A1
公开(公告)日：2020-09-17
申请号：US15733131
申请日：2018-11-26
IPC分类号： A61K31/343 , A61K36/28 , A61K31/121 , A61P3/10
摘要： The invention relates to pharmaceutical compositions comprising combinations of flavonoids that may be used to treat and/or prevent diabetes and associated diseases, conditions and/or disorders. The invention also relates to methods of treating diabetes and associated diseases, conditions and/or disorders using the pharmaceutical compositions.
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7.发明申请ASSEMBLY OF MICELLE AGGREGATES OF SURFACTANT MICELLES AND SILVER NANOPARTICLES AND USE AS ANTIBACTERIAL AGENT 审中-公开表面活性剂微粒和银纳米颗粒的微胶囊组装和用作抗菌剂公开(公告)号：US20150366904A1
公开(公告)日：2015-12-24
申请号：US14763108
申请日：2014-01-24
CPC分类号： A61K33/38 , A61C19/06 , A61K9/0063 , A61K9/1075 , A61K9/14 , A61K47/20 , A61N1/205 , A61N1/30 , Y02A50/473
摘要： An assembly of micelle aggregates, wherein each aggregate comprises micelles of an anionic surfactant and nano-sized particles of metallic silver. A product comprising such assemblies for use in treating or preventing bacterial infections.
摘要翻译： 胶束聚集体的组件，其中每个聚集体包含阴离子表面活性剂的胶束和金属银的纳米尺寸颗粒。 包含用于治疗或预防细菌感染的组合物的产品。
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公开(公告)号：US20240288746A1
公开(公告)日：2024-08-29
申请号：US18573334
申请日：2022-06-28
发明人： Nicholas Lambert , Luke Trainor , Harald Schwefel
CPC分类号： G02F1/3501 , G01S7/4815 , G02F1/3534 , G02F1/37 , H01S5/0085 , G02F2202/20 , G02F2203/15 , G02F2203/56
摘要： Techniques dual-frequency comb sources are disclosed. In the illustrative embodiment, a whispering-gallery-mode resonator supports a family of radially-polarized modes and a family of axially-polarized modes. A laser excites one radially-polarized mode and one axial-polarized mode. A microwave field is applied at a free spectral range for each family of modes, coupling the radially-polarized and axially-polarized mode excited by the laser with other modes in the family, creating a dual-frequency comb in the resonator.
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公开(公告)号：US10995186B2
公开(公告)日：2021-05-04
申请号：US15781246
申请日：2016-12-02
IPC分类号： C08J3/28 , A61L27/52 , A61L27/38 , A61L27/54 , C08J3/075 , C08L5/10 , A61L27/56 , C08B37/00 , C08K3/30 , C08K5/56
摘要： A method for preparing a hydrogel comprising mixing a solution of a polymer with a photoinitiator, where the polymer comprises multiple subunits each having a non-aromatic unsaturated functional group, and irradiating the mixture with visible light to produce the hydrogel.
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公开(公告)号：US10763966B1
公开(公告)日：2020-09-01
申请号：US16363965
申请日：2019-03-25
发明人： Amita Bikram Deb , Niels Kjaergaard
IPC分类号： H04B10/2575
摘要： In one embodiment, there is provided an apparatus for converting an analogue radio-frequency (RF) signal to an optical signal. The apparatus may include: a vapor cell enclosing a gas of atoms; a probing light source configured to propagate a probing light beam through the vapor cell, a frequency of the probing light beam being tuned across a range in which the atoms transition from a first quantum state to a second quantum state; and, a coupling light source configured to propagate a coupling light beam through the vapor cell, a frequency of the coupling light beam being resonant or off-resonant with transition of the atoms from the second quantum state to a Rydberg state; wherein the vapor cell is configured such that on exposure thereof to an RF field carrying information from the RF signal, the apparatus is configured to encode the RF signal into the probing light beam.
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