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公开(公告)号：US20120231043A1
公开(公告)日：2012-09-13
申请号：US13416880
申请日：2012-03-09
申请人： Karin Leontein , Per Antoni , Daniel Nyström , Paul Begovac , Krzysztof Pietrzak
发明人： Karin Leontein , Per Antoni , Daniel Nyström , Paul Begovac , Krzysztof Pietrzak
IPC分类号： A61K31/785 , C09D161/32 , A61L33/06 , A61P7/02 , B32B9/00 , A61K9/00 , C09D177/00
CPC分类号： A61L33/0011 , A61L27/34 , A61L29/085 , A61L31/10 , A61L33/0035 , A61L33/0064 , A61L33/0076 , A61L33/068 , A61L33/08 , A61L2300/42 , A61L2300/452 , C08G81/00 , Y10T428/31971 , C08L101/005 , C08L79/02 , C08L79/08
摘要： There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da (ii) a total molecular weight of 1,500 to 1,000,000 Da (iii) a ratio of total molecular weight to core moiety molecular weight of at least 80:1 and (iv) functional end groups, whereby one or more of said functional end groups have an anti-coagulant entity covalently attached thereto.
摘要翻译： 尤其描述了具有包括层状涂层的表面的装置，其中外涂层包含多个阳离子超支化聚合物分子，其特征在于具有（i）分子量为14-1,000Da的芯部分（ii）总分子量 （iii）总分子量与核心部分分子量的比例为至少80:1，和（iv）官能端基，其中一个或多个所述官能端基具有共价连接的抗凝剂实体 到此。
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公开(公告)号：US20150367040A1
公开(公告)日：2015-12-24
申请号：US14790205
申请日：2015-07-02
申请人： Karin Leontein , Per Antoni , Daniel Nyström , Paul Begovac , Krzysztof Pietrzak
发明人： Karin Leontein , Per Antoni , Daniel Nyström , Paul Begovac , Krzysztof Pietrzak
CPC分类号： A61L33/0011 , A61L27/34 , A61L29/085 , A61L31/10 , A61L33/0035 , A61L33/0064 , A61L33/0076 , A61L33/068 , A61L33/08 , A61L2300/42 , A61L2300/452 , C08G81/00 , Y10T428/31971 , C08L101/005 , C08L79/02 , C08L79/08
摘要： There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da (ii) a total molecular weight of 1,500 to 1,000,000 Da (iii) a ratio of total molecular weight to core moiety molecular weight of at least 80:1 and (iv) functional end groups, whereby one or more of said functional end groups have an anti-coagulant entity covalently attached thereto.
摘要翻译： 尤其描述了具有包括层状涂层的表面的装置，其中外涂层包含多个阳离子超支化聚合物分子，其特征在于具有（i）分子量为14-1,000Da的芯部分（ii）总分子量 （iii）总分子量与核心部分分子量的比例为至少80:1，和（iv）官能端基，其中一个或多个所述官能端基具有共价连接的抗凝剂实体 到此。
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公开(公告)号：US20060025852A1
公开(公告)日：2006-02-02
申请号：US10910502
申请日：2004-08-02
申请人： Joseph Armstrong , Paul Begovac , Robert Cleek , Edward Cully , Charles Flynn , Byron Hayes , Ryan Peterson , Michael Vonesh , Charles White
发明人： Joseph Armstrong , Paul Begovac , Robert Cleek , Edward Cully , Charles Flynn , Byron Hayes , Ryan Peterson , Michael Vonesh , Charles White
IPC分类号： A61F2/06
CPC分类号： A61F2/01 , A61B17/12022 , A61B17/12118 , A61B17/1214 , A61B2017/1205 , A61F2/91 , A61F2/915 , A61F2002/016 , A61F2002/018 , A61F2002/30062 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155 , A61F2210/0004 , A61F2210/0076 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0069 , A61F2230/008 , A61F2250/003 , A61L31/06 , A61L31/148 , C08L67/04
摘要： The present invention is directed to bioabsorbable self-expanding medical devices for use inside or outside body conduits that self-expand at, or below, normal human body temperature without requisite for a polymeric thermal transition
摘要翻译： 本发明涉及用于在正常人体温度下或在正常人体温度下自身膨胀而在聚合物热转变条件下自身膨胀的身体管道内部或外部的生物可吸收自扩张医疗装置
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公开(公告)号：US09408950B2
公开(公告)日：2016-08-09
申请号：US14790205
申请日：2015-07-02
申请人： Karin Leontein , Per Antoni , Daniel Nyström , Paul Begovac , Krzysztof Pietrzak
发明人： Karin Leontein , Per Antoni , Daniel Nyström , Paul Begovac , Krzysztof Pietrzak
IPC分类号： A61L27/14 , A61L27/54 , A61L29/16 , A61L29/08 , A61L31/10 , A61L27/34 , A61L33/00 , C08G81/00
CPC分类号： A61L33/0011 , A61L27/34 , A61L29/085 , A61L31/10 , A61L33/0035 , A61L33/0064 , A61L33/0076 , A61L33/068 , A61L33/08 , A61L2300/42 , A61L2300/452 , C08G81/00 , Y10T428/31971 , C08L101/005 , C08L79/02 , C08L79/08
摘要： There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da (ii) a total molecular weight of 1,500 to 1,000,000 Da (iii) a ratio of total molecular weight to core moiety molecular weight of at least 80:1 and (iv) functional end groups, whereby one or more of said functional end groups have an anti-coagulant entity covalently attached thereto.
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公开(公告)号：US09101696B2
公开(公告)日：2015-08-11
申请号：US13416880
申请日：2012-03-09
申请人： Karin Leontein , Per Antoni , Daniel Nyström , Paul Begovac , Krzysztof Pietrzak
发明人： Karin Leontein , Per Antoni , Daniel Nyström , Paul Begovac , Krzysztof Pietrzak
CPC分类号： A61L33/0011 , A61L27/34 , A61L29/085 , A61L31/10 , A61L33/0035 , A61L33/0064 , A61L33/0076 , A61L33/068 , A61L33/08 , A61L2300/42 , A61L2300/452 , C08G81/00 , Y10T428/31971 , C08L101/005 , C08L79/02 , C08L79/08
摘要： There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da (ii) a total molecular weight of 1,500 to 1,000,000 Da (iii) a ratio of total molecular weight to core moiety molecular weight of at least 80:1 and (iv) functional end groups, whereby one or more of said functional end groups have an anti-coagulant entity covalently attached thereto.
摘要翻译： 尤其描述了具有包括层状涂层的表面的装置，其中外涂层包含多个阳离子超支化聚合物分子，其特征在于具有（i）分子量为14-1,000Da的芯部分（ii）总分子量 （iii）总分子量与核心部分分子量的比例为至少80:1，和（iv）官能端基，其中一个或多个所述官能端基具有共价连接的抗凝剂实体 到此。
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