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公开(公告)号：US06952011B2
公开(公告)日：2005-10-04
申请号：US10223401
申请日：2002-08-19
申请人： Jeff Brown , Dominic Gostick , Edouard S. P. Bouvier , John Charles Gebler , Peter Jeng Jong Lee , James Ian Langridge , Emmanuelle Claude , Weibin Chen
发明人： Jeff Brown , Dominic Gostick , Edouard S. P. Bouvier , John Charles Gebler , Peter Jeng Jong Lee , James Ian Langridge , Emmanuelle Claude , Weibin Chen
CPC分类号： H01J49/0418 , B01L3/5088
摘要： A MALDI sample plate 1 is disclosed which comprises a metallic substrate 2 having a circular groove or moat 3. A hydrophobic polytetrafluoroethylene layer 4 is applied to the substrate 2 and a central portion 5 of the substrate 2 is laser etched which roughens the surface of the substrate 2. A thin polystyrene layer is then applied to the polytetrafluoroethylene layer 4 and the central portion 5.
摘要翻译： 公开了一种MALDI样品板1，其包括具有圆形凹槽或护城河3的金属基底2。 将疏水性聚四氟乙烯层4施加到基板2上，对基板2的中心部5进行激光蚀刻，使基板2的表面粗糙化。 然后将薄聚苯乙烯层施加到聚四氟乙烯层4和中心部分5。
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公开(公告)号：US08580533B2
公开(公告)日：2013-11-12
申请号：US10516418
申请日：2003-05-30
申请人： Edouard S. P. Bouvier , Bruce J. Compton , John C. Gebler , Martin Gilar , Ying-Qing Yu , Peter Jeng-Jong Lee , Elizabeth K. Brown
发明人： Edouard S. P. Bouvier , Bruce J. Compton , John C. Gebler , Martin Gilar , Ying-Qing Yu , Peter Jeng-Jong Lee , Elizabeth K. Brown
IPC分类号： C12Q1/37 , A61K31/095
CPC分类号： C12Q1/37 , C12P21/06 , G01N27/44726 , G01N27/44747 , G01N33/5306
摘要： The present invention provides methods for enhancing chemical reactions of molecules, e.g., biomolecules, with destructible surfactants. The chemical reactions may involve and/or be associate with analysis, e.g., solubilizing, separating, purifying and/or characterizing the molecules. In one aspect, the anionic surfactants of the present invention may be selectively broken up at relatively low pH. The resulting breakdown products of the surfactants may be removed from the molecule/sample with relative ease. The invention has applicability in a variety of analytical techniques.
摘要翻译： 本发明提供了增强具有可破坏表面活性剂的分子（例如生物分子）的化学反应的方法。 化学反应可能涉及和/或与分析有关，例如增溶，分离，纯化和/或表征分子。 在一个方面，本发明的阴离子表面活性剂可以在相对低的pH下选择性地分解。 可以相对容易地从分子/样品中除去所得表面活性剂的分解产物。 本发明适用于各种分析技术。
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公开(公告)号：US07294831B2
公开(公告)日：2007-11-13
申请号：US11196820
申请日：2005-08-03
申请人： Jeff Brown , Dominic Gostick , Edouard S. P. Bouvier , John Charles Gebler , Peter Jeng Jong Lee , James Ian Langridge , Emmanuelle Claude , Weibin Chen
发明人： Jeff Brown , Dominic Gostick , Edouard S. P. Bouvier , John Charles Gebler , Peter Jeng Jong Lee , James Ian Langridge , Emmanuelle Claude , Weibin Chen
IPC分类号： H01J49/04
CPC分类号： H01J49/0418 , B01L3/5088
摘要： A MALDI sample plate 1 is disclosed which comprises a metallic substrate 2 having a circular groove or moat 3. A hydrophobic polytetrafluoroethylene layer 4 is applied to the substrate 2 and a central portion 5 of the substrate 2 is laser etched which roughens the surface of the substrate 2. A thin polystyrene layer is then applied to the polytetrafluoroethylene layer 4 and the central portion 5.
摘要翻译： 公开了一种MALDI样品板1，其包括具有圆形凹槽或护城河3的金属基底2。 将疏水性聚四氟乙烯层4施加到基板2上，对基板2的中心部5进行激光蚀刻，使基板2的表面粗糙化。 然后将薄聚苯乙烯层施加到聚四氟乙烯层4和中心部分5。
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4.发明授权公开(公告)号：US07232520B1
公开(公告)日：2007-06-19
申请号：US10169546
申请日：1999-06-10
IPC分类号： B01D15/08
CPC分类号： B01J39/26 , B01J20/26 , B01J20/261 , B01J20/285 , B01J20/3285 , B01J39/20 , B01J41/14 , B01J41/20 , C08F8/24 , C08F8/32 , C08F8/36 , C08F2800/20 , C08F212/36
摘要： Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.
摘要翻译： 本发明的实施方案涉及用于固相萃取的多孔树脂。 该树脂具有至少一种疏水性组分，至少一种亲水组分和至少一种离子交换官能团。 树脂表现出优异的润湿和离子交换性能。
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公开(公告)号：US07229539B1
公开(公告)日：2007-06-12
申请号：US10169002
申请日：2000-05-12
IPC分类号： G01N27/447 , G01N27/453 , G01N30/02 , B01D15/08 , C11D3/00
CPC分类号： B01F17/0057 , B01D15/203 , G01N27/44747 , G01N30/02 , G01N30/04 , B01D15/366
摘要： Destructible surfactants and methods of using same are provided. The invention includes anionic surfactants having a dioxolane or dioxane functional group which enables the surfactant to be broken down under acidic conditions. The invention also includes methods of making anionic surfactants and methods of using anionic surfactants in a variety of applications.
摘要翻译： 提供了可破坏的表面活性剂及其使用方法。 本发明包括具有二氧戊环或二恶烷官能团的阴离子表面活性剂，其使表面活性剂在酸性条件下分解。 本发明还包括制备阴离子表面活性剂的方法和在各种应用中使用阴离子表面活性剂的方法。
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6.发明授权公开(公告)号：US08574433B2
公开(公告)日：2013-11-05
申请号：US12855300
申请日：2010-08-12
IPC分类号： B01D15/08
CPC分类号： B01J20/26 , B01J20/261 , B01J20/264 , B01J20/28042 , B01J20/285 , B01J20/3285 , B01J39/20 , B01J39/26 , B01J41/20 , B01J2220/54 , B01J2220/58 , B01J2220/62 , B01J2220/66 , B01J2220/82 , C08F8/24 , C08F8/32 , C08F8/36 , C08F2800/20 , G01N30/02 , B01D15/361 , C08F212/36
摘要： Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.
摘要翻译： 本发明的实施方案涉及用于固相萃取的多孔树脂。 该树脂具有至少一种疏水性组分，至少一种亲水组分和至少一种离子交换官能团。 树脂表现出优异的润湿和离子交换性能。
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7.发明申请NOVEL ION EXCHANGE POROUS RESINS FOR SOLID PHASE EXTRACTION AND CHROMATOGRAPHY 有权用于固相萃取和色谱的新型离子交换树脂公开(公告)号：US20090139323A1
公开(公告)日：2009-06-04
申请号：US12259199
申请日：2008-10-27
IPC分类号： G01F23/00
CPC分类号： B01J20/26 , B01J20/261 , B01J20/264 , B01J20/28042 , B01J20/285 , B01J20/3285 , B01J39/20 , B01J39/26 , B01J41/20 , B01J2220/54 , B01J2220/58 , B01J2220/62 , B01J2220/66 , B01J2220/82 , C08F8/24 , C08F8/32 , C08F8/36 , C08F2800/20 , G01N30/02 , B01D15/361 , C08F212/36
摘要： Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.
摘要翻译： 本发明的实施方案涉及用于固相萃取的多孔树脂。 该树脂具有至少一种疏水性组分，至少一种亲水组分和至少一种离子交换官能团。 树脂表现出优异的润湿和离子交换性能。
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公开(公告)号：US20050274885A1
公开(公告)日：2005-12-15
申请号：US11196820
申请日：2005-08-03
申请人： Jeff Brown , Dominic Gostick , Edouard Bouvier , John Charles Gebler , Peter Jeng Jong Lee , James Ian Langridge , Emmanuelle Claude , Weibin Chen
发明人： Jeff Brown , Dominic Gostick , Edouard Bouvier , John Charles Gebler , Peter Jeng Jong Lee , James Ian Langridge , Emmanuelle Claude , Weibin Chen
CPC分类号： H01J49/0418 , B01L3/5088
摘要： A MALDI sample plate 1 is disclosed which comprises a metallic substrate 2 having a circular groove or moat 3. A hydrophobic polytetrafluoroethylene layer 4 is applied to the substrate 2 and a central portion 5 of the substrate 2 is laser etched which roughens the surface of the substrate 2. A thin polystyrene layer is then applied to the polytetrafluoroethylene layer 4 and the central portion 5.
摘要翻译： 公开了一种MALDI样品板1，其包括具有圆形槽或护城河3的金属基板2.将疏水性聚四氟乙烯层4施加到基板2上，并且激光蚀刻基板2的中心部分5，其粗糙化表面 然后将薄聚苯乙烯层施加到聚四氟乙烯层4和中心部分5。
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9.发明申请NOVEL ION EXCHANGE POROUS RESINS FOR SOLID PHASE EXTRACTION AND CHROMATOGRAPHY 有权用于固相萃取和色谱的新型离子交换树脂公开(公告)号：US20100324159A1
公开(公告)日：2010-12-23
申请号：US12855300
申请日：2010-08-12
IPC分类号： C08J5/20 , B01J39/20 , C07D473/12 , C07D307/02 , C07C237/00 , C07D307/66 , C07C233/25 , C07C211/01 , C07C211/47 , B01D15/04
CPC分类号： B01J20/26 , B01J20/261 , B01J20/264 , B01J20/28042 , B01J20/285 , B01J20/3285 , B01J39/20 , B01J39/26 , B01J41/20 , B01J2220/54 , B01J2220/58 , B01J2220/62 , B01J2220/66 , B01J2220/82 , C08F8/24 , C08F8/32 , C08F8/36 , C08F2800/20 , G01N30/02 , B01D15/361 , C08F212/36
摘要： Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.
摘要翻译： 本发明的实施方案涉及用于固相萃取的多孔树脂。 该树脂具有至少一种疏水性组分，至少一种亲水组分和至少一种离子交换官能团。 树脂表现出优异的润湿和离子交换性能。
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10.发明授权公开(公告)号：US07790038B2
公开(公告)日：2010-09-07
申请号：US12259199
申请日：2008-10-27
IPC分类号： B01D15/08
CPC分类号： B01J20/26 , B01J20/261 , B01J20/264 , B01J20/28042 , B01J20/285 , B01J20/3285 , B01J39/20 , B01J39/26 , B01J41/20 , B01J2220/54 , B01J2220/58 , B01J2220/62 , B01J2220/66 , B01J2220/82 , C08F8/24 , C08F8/32 , C08F8/36 , C08F2800/20 , G01N30/02 , B01D15/361 , C08F212/36
摘要： Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.
摘要翻译： 本发明的实施方案涉及用于固相萃取的多孔树脂。 该树脂具有至少一种疏水性组分，至少一种亲水组分和至少一种离子交换官能团。 树脂表现出优异的润湿和离子交换性能。
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