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1.发明授权Fluidic flow cytometry devices and particle sensing based on signal-encoding 有权基于信号编码的流式流式细胞术装置和粒子感测公开(公告)号：US09134221B2
公开(公告)日：2015-09-15
申请号：US13254851
申请日：2010-03-10
Applicant: Yu-Hwa Lo , Chun Hao Randy Chen , Sung Hwan Cho , Frank Tsai
Inventor： Yu-Hwa Lo , Chun Hao Randy Chen , Sung Hwan Cho , Frank Tsai
CPC classification number: G01N15/1434 , G01N15/1425 , G01N15/1459 , G01N15/1484 , G01N2015/0065 , G01N2015/1006 , G01N2015/1415 , G01N2015/1447 , G01N2015/145 , G01N2015/149
Abstract: Microfluidic devices, systems and techniques in connection with particle sorting in liquid, including cytometry devices and techniques and applications in chemical or biological testing and diagnostic measurements.
Abstract translation: 与流体中颗粒分选有关的微流体装置，系统和技术，包括细胞计量装置和化学或生物测试和诊断测量中的技术和应用。
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公开(公告)号：US20050183306A1
公开(公告)日：2005-08-25
申请号：US10785258
申请日：2004-02-24
Applicant: David Helmlinger , Stephen Weiss , Randy Chen
Inventor： David Helmlinger , Stephen Weiss , Randy Chen
CPC classification number: G09F27/00 , B42D5/006 , B43K23/001 , B43M99/001 , B43M99/008 , B43M99/009 , G09F3/20
Abstract: A motion-detecting note holder is disclosed. Such a note holder includes a note retention member, a motion sensor, a note-waiting indicator, and a controller in communication with the motion sensor and the note-waiting indicator. The controller, upon receiving a motion-detection signal from the motion sensor, causes the note-waiting indicator to provide a human-perceptible indication that a note is in the note retention member.
Abstract translation: 公开了运动检测纸币支架。 这样的记录保持器包括笔记保持构件，运动传感器，笔记等待指示器以及与运动传感器和音符等待指示器通信的控制器。 控制器在从运动传感器接收到运动检测信号时，使笔记等待指示器提供人可感知的指示音符在笔记保持构件中。
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3.发明申请公开(公告)号：US20130004987A1
公开(公告)日：2013-01-03
申请号：US13605925
申请日：2012-09-06
Applicant: Yu-Hwa Lo , Victor Jie Lien , Chun Hao Randy Chen
Inventor： Yu-Hwa Lo , Victor Jie Lien , Chun Hao Randy Chen
CPC classification number: G01N15/1429 , B01L3/502707 , B01L3/502715 , B01L2200/0668 , B01L2300/0654 , B01L2300/0816 , B01L2400/0424 , B01L2400/0487 , G01N15/1434 , G01N15/1484 , G01N21/05 , G01N21/49 , G01N21/53 , G01N21/6408 , G01N2021/0346 , Y10T29/49124
Abstract: A number of fluidic-photonic devices for allowing optical detection, systems employing such devices, and related methods of operation and fabrication of such devices are disclosed herein. In at least some embodiments, the devices can serve as flow cytometry devices and/or employ microfluidic channels. Also, in at least some embodiments, the devices are fluidic-photonic integrated circuit (FPIC) devices that employ both fluidic channels and one or more waveguides capable of receiving and/or delivering light, and that can be fabricated using polymeric materials. The fluidic-photonic devices in at least some embodiments are capable of functionality such as on-chip excitation, time-of-flight measurement, and can experience enhanced fluorescence detection sensitivity. In at least some embodiments, the devices employ detection waveguides that are joined by way of a waveguide demultiplexer. In additional embodiments, a variety of techniques can be used to process information received via the waveguides, including an iterative cross-correlation process.
Abstract translation: 本文公开了许多用于允许光学检测的流体光子学装置，采用这种装置的系统以及这些装置的相关操作和制造方法。 在至少一些实施方案中，装置可以用作流式细胞术装置和/或使用微流体通道。 此外，在至少一些实施例中，装置是采用流体通道和能够接收和/或传送光的一个或多个波导的流体 - 光子学集成电路（FPIC）装置，并且可以使用聚合材料制造。 至少一些实施例中的流体光子学装置能够具有诸如片上激发，飞行时间测量等功能，并且可以体验增强的荧光检测灵敏度。 在至少一些实施例中，器件采用通过波导解复用器连接的检测波导。 在另外的实施例中，可以使用各种技术来处理经由波导接收的信息，包括迭代互相关过程。
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Patent Agency Ranking
4.发明申请公开(公告)号：US20090155832A1
公开(公告)日：2009-06-18
申请号：US12091414
申请日：2006-10-27
Applicant: Yu-Hwa Lo , Victor Jie Lien , Chun Hao Randy Chen
Inventor： Yu-Hwa Lo , Victor Jie Lien , Chun Hao Randy Chen
CPC classification number: G01N15/1429 , B01L3/502707 , B01L3/502715 , B01L2200/0668 , B01L2300/0654 , B01L2300/0816 , B01L2400/0424 , B01L2400/0487 , G01N15/1434 , G01N15/1484 , G01N21/05 , G01N21/49 , G01N21/53 , G01N21/6408 , G01N2021/0346 , Y10T29/49124
Abstract: A number of fluidic-photonic devices for allowing optical detection, systems employing such devices, and related methods of operation and fabrication of such devices are disclosed herein. In at least some embodiments, the devices can serve as flow cytometry devices and/or employ microfiuidic channels. Also, in at least some embodiments, the devices are fluidic-photonic integrated circuit (FPIC) devices that employ both fluidic channels and one or more waveguides capable of receiving and/or delivering light, and that can be fabricated using polymeric materials. The fluidic-photonic devices in at least some embodiments are capable of functionality such as on-chip excitation, time-of-flight measurement, and can experience enhanced fluorescence detection sensitivity. In at least some embodiments, the devices employ detection waveguides that are joined by way of a waveguide demultiplexer. In additional embodiments, a variety of techniques can be used to process information received via the waveguides, including an iterative cross-correlation process.
Abstract translation: 本文公开了许多用于允许光学检测的流体光子学装置，采用这种装置的系统以及这些装置的相关操作和制造方法。 在至少一些实施方案中，该装置可以用作流式细胞术装置和/或使用微流体通道。 此外，在至少一些实施例中，装置是采用流体通道和能够接收和/或传送光的一个或多个波导的流体 - 光子学集成电路（FPIC）装置，并且可以使用聚合材料制造。 至少一些实施例中的流体光子学装置能够具有诸如片上激发，飞行时间测量等功能，并且可以体验增强的荧光检测灵敏度。 在至少一些实施例中，器件采用通过波导解复用器连接的检测波导。 在另外的实施例中，可以使用各种技术来处理经由波导接收的信息，包括迭代互相关过程。
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5.发明授权公开(公告)号：US08270781B2
公开(公告)日：2012-09-18
申请号：US12091414
申请日：2006-10-27
Applicant: Yu-Hwa Lo , Victor Jie Lien , Chun Hao Randy Chen
Inventor： Yu-Hwa Lo , Victor Jie Lien , Chun Hao Randy Chen
IPC: G02B6/00
CPC classification number: G01N15/1429 , B01L3/502707 , B01L3/502715 , B01L2200/0668 , B01L2300/0654 , B01L2300/0816 , B01L2400/0424 , B01L2400/0487 , G01N15/1434 , G01N15/1484 , G01N21/05 , G01N21/49 , G01N21/53 , G01N21/6408 , G01N2021/0346 , Y10T29/49124
Abstract: A number of fluidic-photonic devices for allowing optical detection, systems employing such devices, and related methods of operation and fabrication of such devices are disclosed herein. In at least some embodiments, the devices can serve as flow cytometry devices and/or employ microfluidic channels. Also, in at least some embodiments, the devices are fluidic-photonic integrated circuit (FPIC) devices that employ both fluidic channels and one or more waveguides capable of receiving and/or delivering light, and that can be fabricated using polymeric materials. The fluidic-photonic devices in at least some embodiments are capable of functionality such as on-chip excitation, time-of-flight measurement, and can experience enhanced fluorescence detection sensitivity. In at least some embodiments, the devices employ detection waveguides that are joined by way of a waveguide demultiplexer. In additional embodiments, a variety of techniques can be used to process information received via the waveguides, including an iterative cross-correlation process.
Abstract translation: 本文公开了许多用于允许光学检测的流体光子学装置，采用这种装置的系统以及这些装置的相关操作和制造方法。 在至少一些实施方案中，装置可以用作流式细胞术装置和/或使用微流体通道。 此外，在至少一些实施例中，装置是采用流体通道和能够接收和/或传送光的一个或多个波导的流体 - 光子学集成电路（FPIC）装置，并且可以使用聚合材料制造。 至少一些实施例中的流体光子学装置能够具有诸如片上激发，飞行时间测量等功能，并且可以体验增强的荧光检测灵敏度。 在至少一些实施例中，器件采用通过波导解复用器连接的检测波导。 在另外的实施例中，可以使用各种技术来处理经由波导接收的信息，包括迭代互相关过程。
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6.发明申请FLUIDIC FLOW CYTOMETRY DEVICES AND PARTICLE SENSING BASED ON SIGNAL-ENCODING 有权基于信号编码的流体流式细胞仪装置和颗粒感测公开(公告)号：US20120078531A1
公开(公告)日：2012-03-29
申请号：US13254851
申请日：2010-03-10
Applicant: Yu-Hwa Lo , Chun Hao Randy Chen , Sung Hwan Cho , Frank Tsai
Inventor： Yu-Hwa Lo , Chun Hao Randy Chen , Sung Hwan Cho , Frank Tsai
CPC classification number: G01N15/1434 , G01N15/1425 , G01N15/1459 , G01N15/1484 , G01N2015/0065 , G01N2015/1006 , G01N2015/1415 , G01N2015/1447 , G01N2015/145 , G01N2015/149
Abstract: Microfluidic devices, systems and techniques in connection with particle sorting in liquid, including cytometry devices and techniques and applications in chemical or biological testing and diagnostic measurements.
Abstract translation: 与流体中颗粒分选有关的微流体装置，系统和技术，包括细胞计量装置和化学或生物测试和诊断测量中的技术和应用。
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公开(公告)号：US20050229455A1
公开(公告)日：2005-10-20
申请号：US11064396
申请日：2005-02-23
Applicant: David Helmlinger , Stephen Weiss , Randy Chen
Inventor： David Helmlinger , Stephen Weiss , Randy Chen
IPC: A63H5/00
CPC classification number: G09F27/005 , A47G2200/08 , A47G2200/143 , B42D5/006 , B43K23/001 , B43L1/00 , B43L1/04 , B43M99/001 , B43M99/008 , B43M99/009 , G09F27/00 , G09F2027/001 , G09F2027/002
Abstract: A motion-detecting note holder is disclosed. Such a note holder may include a message writing surface, a switch, a motion sensor, a note-waiting indicator, and a controller in communication with the switch, the motion sensor, and the note-waiting indicator. When the switch is actuated, the controller, upon receiving a motion-detection signal from the motion sensor, may cause the note-waiting indicator to provide a human-perceptible indication that a note is waiting on the message writing surface. The message writing surface may include an easy erasure message writing surface.
Abstract translation: 公开了运动检测纸币支架。 这种记录保持器可以包括消息写入表面，开关，运动传感器，音符等待指示器和与开关，运动传感器和音符等待指示器通信的控制器。 当开关被致动时，控制器在从运动传感器接收到运动检测信号时，可能导致音符等待指示符提供一个人感知的指示，即音符正在消息写入表面上等待。 消息写入表面可以包括简单的擦除消息写入表面。
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8.发明授权公开(公告)号：US08717569B2
公开(公告)日：2014-05-06
申请号：US13605925
申请日：2012-09-06
Applicant: Yu-Hwa Lo , Victor Jie Lien , Chun Hao Randy Chen
Inventor： Yu-Hwa Lo , Victor Jie Lien , Chun Hao Randy Chen
IPC: G01N21/00
CPC classification number: G01N15/1429 , B01L3/502707 , B01L3/502715 , B01L2200/0668 , B01L2300/0654 , B01L2300/0816 , B01L2400/0424 , B01L2400/0487 , G01N15/1434 , G01N15/1484 , G01N21/05 , G01N21/49 , G01N21/53 , G01N21/6408 , G01N2021/0346 , Y10T29/49124
Abstract: A number of fluidic-photonic devices for allowing optical detection, systems employing such devices, and related methods of operation and fabrication of such devices are disclosed herein. In at least some embodiments, the devices can serve as flow cytometry devices and/or employ microfluidic channels. Also, in at least some embodiments, the devices are fluidic-photonic integrated circuit (FPIC) devices that employ both fluidic channels and one or more waveguides capable of receiving and/or delivering light, and that can be fabricated using polymeric materials. The fluidic-photonic devices in at least some embodiments are capable of functionality such as on-chip excitation, time-of-flight measurement, and can experience enhanced fluorescence detection sensitivity. In at least some embodiments, the devices employ detection waveguides that are joined by way of a waveguide demultiplexer. In additional embodiments, a variety of techniques can be used to process information received via the waveguides, including an iterative cross-correlation process.
Abstract translation: 本文公开了许多用于允许光学检测的流体光子学装置，采用这种装置的系统以及这些装置的相关操作和制造方法。 在至少一些实施方案中，装置可以用作流式细胞术装置和/或使用微流体通道。 此外，在至少一些实施例中，装置是采用流体通道和能够接收和/或传送光的一个或多个波导的流体 - 光子学集成电路（FPIC）装置，并且可以使用聚合材料制造。 至少一些实施例中的流体光子学装置能够具有诸如片上激发，飞行时间测量等功能，并且可以体验增强的荧光检测灵敏度。 在至少一些实施例中，器件采用通过波导解复用器连接的检测波导。 在另外的实施例中，可以使用各种技术来处理经由波导接收的信息，包括迭代互相关过程。
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