公开(公告)号：US20170080067A1

公开(公告)日：2017-03-23

申请号：US15126500

申请日：2015-03-17

Applicant: Bundesrepublik Deutschland Ietztvertreten durch da s Robert Koch-Institut vertreten durch seinen Prä

Inventor： Richard KROCZEK

IPC: A61K39/00

CPC classification number: A61K39/0011 ,  A61K2039/5154 ,  A61K2039/5158 ,  A61K2039/545 ,  A61K2039/55533 ,  A61K2039/55561 ,  A61K2039/572

Abstract: The present invention relates to a medicament for use in a method of inducing a cellular cytotoxic immune response, the method comprising the steps of: i) administering to a patient a delivery system comprising (a) a molecule binding to a receptor on the surface of a dendritic cell, (b) an antigen-comprising protein bound to molecule of (a) and (c) a first adjuvant, wherein upon binding of the molecule of (a) to the receptor, the protein of (b) is internalized and processed in the dendritic cell and the antigen comprised in the protein is presented on the surface of the dendritic cell, thereby activating a T cell in the patient; and ii) administering to the patient a re-activator selected from the group consisting of (d) complexed interleukin 2 (IL-2cx), (e) a peptide-loaded major histocompatibility complex class I (MHC-I) presenting cell and a second adjuvant, and (f) a combination of (d) and (e), wherein the peptide is derived from the antigen-comprising protein as defined in step i), thereby reactivating the T cell activated in step i), wherein the re-activator of step ii) is administered in a time frame of from 0 h to 14 days after the administration of the delivery system of step i).

公开(公告)号：US20160372804A1

公开(公告)日：2016-12-22

申请号：US14901983

申请日：2014-08-01

Applicant: Robert KOCH ,  Babu POTTI ,  Jeffrey HOLZ ,  Robert Bosch GmbH

Inventor： Robert Koch ,  Babu Potti ,  Jeffrey Buckholz

IPC: H01M10/6557 ,  H01M10/647 ,  H01M10/613 ,  H01M2/10 ,  H01M10/6555

CPC classification number: H01M10/6557 ,  H01M2/1077 ,  H01M10/613 ,  H01M10/647 ,  H01M10/6555 ,  H01M10/6567

Abstract: A battery assembly in one embodiment includes a battery case defining a first plurality of battery compartments and a second plurality of battery compartments, and a thermal plate defined between the first plurality of battery compartments and the second plurality of battery compartments, the thermal plate including a channel divider dividing the thermal plate into an inlet channel portion located between the first plurality of battery compartments and the second plurality of battery compartments, and an outlet channel portion located between the first plurality of battery compartments and the second plurality of battery compartments, wherein the channel divider includes a first divider portion which extends substantially parallel to outer sides of the inlet channel and the outlet channel, and a second divider portion which curves toward the outer side of the inlet channel portion thereby narrowing the inlet channel portion.

Abstract translation: 在一个实施例中的电池组件包括限定第一多个电池隔室的电池壳体和第二多个电池隔室，以及限定在第一多个电池隔间与第二多个电池隔间之间的热板，该热板包括 通道分隔器将热板分隔成位于第一多个电池室和第二多个电池隔间之间的入口通道部分，以及位于第一多个电池隔间与第二多个电池室之间的出口通道部分，其中， 通道分隔器包括基本上平行于入口通道和出口通道的外侧延伸的第一分隔部分，以及朝向入口通道部分的外侧弯曲的第二分隔部分，从而使入口通道部分变窄。

公开(公告)号：US08776149B1

公开(公告)日：2014-07-08

申请号：US11682166

申请日：2007-03-05

Applicant: Robert Koch ,  Steven N. Tischer

Inventor： Robert Koch ,  Steven N. Tischer

IPC: H04N7/173 ,  G06F3/00

CPC classification number: H04N21/47214 ,  H04N21/4334 ,  H04N21/44204 ,  H04N21/44222

Abstract: When a user is consuming media content from a first source, one or more other available sources of media content may be monitored and the user may be notified if other available content matches the user's profile.

Abstract translation: 当用户正在从第一来源消费媒体内容时，可以监视媒体内容的一个或多个其他可用来源，并且如果其他可用内容与用户的简档匹配，则可以通知用户。

公开(公告)号：US20140056397A1

公开(公告)日：2014-02-27

申请号：US13822558

申请日：2012-05-18

Applicant: Erhard Friedrich ,  Robert Koch ,  Dirk Blavius ,  James Tolar

Inventor： Erhard Friedrich ,  Robert Koch ,  Dirk Blavius ,  James Tolar

IPC: G21C3/32

CPC classification number: G21C3/3206 ,  G21C3/32 ,  G21C3/322 ,  Y02E30/38

Abstract: A debris filter for a nuclear reactor installation is provided. The debris filter comprises a plurality of plates arranged side-by-side in a spaced relationship and delimiting between them flow passages extending through the debris filter from a lower inlet face to an upper outlet face of the debris filter, each passage having an intermediate section offset with respect to an inlet section and an outlet section. At least one of the plates is formed with debris catching features distributed along the plate and protruding into at least one passage delimited by the plate.

Abstract translation: 提供了用于核反应堆安装的碎屑过滤器。 碎片过滤器包括以间隔开的方式并排布置的多个板，并且在它们之间限定从碎屑过滤器延伸通过碎屑过滤器的流动通道，其从碎屑过滤器的下入口面到上出口面，每个通道具有中间部分 相对于入口部分和出口部分偏移。 至少一个板形成有沿着板分布的碎屑捕获特征并且突出到由板限定的至少一个通道中。

公开(公告)号：US08521413B2

公开(公告)日：2013-08-27

申请号：US13274633

申请日：2011-10-17

Applicant: Robert Koch

Inventor： Robert Koch

IPC: G01C21/00

CPC classification number: G06F17/30289 ,  G01C21/00 ,  G06F17/00 ,  G06F17/30241 ,  H04L67/18 ,  H04L67/22 ,  H04W4/027 ,  H04W4/029

Abstract: Methods, systems, and computer-readable media provide for the detection, location stamping, and logging of electronic events and subsequent generation of habitat information. According to implementations, electronic events are detected and location stamped. Associated descriptions and other data corresponding to the electronic events is retrieved and stored along with the geographic locations of the electronic events in an activity log. The information in the activity log is used to generate visual representations of one or more geographic areas in which electronic events that meet user-defined or default criteria occurred within a predetermined frequency.

Abstract translation: 方法，系统和计算机可读介质提供电子事件的检测，位置戳记和记录以及随后的栖息地信息的生成。 根据实施方式，检测电子事件并对其进行位置戳记。 将与电子事件相对应的相关描述和其他数据与电子事件的地理位置一起检索并存储在活动日志中。 活动日志中的信息用于生成一个或多个地理区域的视觉表示，其中满足用户定义或默认标准的电子事件在预定频率内发生。

公开(公告)号：US08282306B2

公开(公告)日：2012-10-09

申请号：US12308917

申请日：2008-02-29

Applicant: Robert Koch ,  Lothar Scharf

Inventor： Robert Koch ,  Lothar Scharf

IPC: F16J1/16

CPC classification number: B61G5/02 ,  B60D1/30 ,  B60D1/50 ,  B60D2001/546 ,  B62D47/025 ,  B62D53/021 ,  B62D53/0871 ,  Y10T403/32893

Abstract: A joint (1) between two vehicle components (2, 3) joined to each other with a hinge, such as of an articulated vehicle, comprising an articulated joint (10), wherein the articulated joint (10) comprises two joint segments (11, 12) that are rotatably connected to each other by a tensioning device (20) acting as a vertical axis, the one, first joint segment (11) having a U-shaped, jaw-like opening (13) for seizing the other, second joint segment (12) in the region of the vertical axis, sliding devices (16) being provided between the joint segments (11, 12) and acting in at least the axial direction, the tensioning device (2) operable to generate pretension on the joint segments (11, 12), the one joint segment (11) having two joint segment elements (11a, 11b) that are each separately fastened with screws to the frame (40) of the vehicle frame (3).

Abstract translation: 铰链（如铰接式车辆）相互连接的两个车辆部件（2,3）之间的接头（1）包括铰接接头（10），其中铰接接头（10）包括两个接头段（11） ，12），其通过用作竖直轴线的张紧装置（20）彼此可旋转地连接，所述一个第一接头段（11）具有用于抓住另一个的U形的颚状开口（13） 第二接头段（12）在垂直轴线的区域中，滑动装置（16）设置在接头段（11,12）之间并且至少沿轴向作用，张紧装置（2）可操作以产生预紧力 所述接头段（11,12），所述一个接头段（11）具有两个接头段元件（11a，11b），每个接头段元件分别用螺钉连接到车架（3）的框架（40）上。

公开(公告)号：US08180859B2

公开(公告)日：2012-05-15

申请号：US12958297

申请日：2010-12-01

Applicant: Robert Koch ,  Robert Andres

Inventor： Robert Koch ,  Robert Andres

IPC: G06F15/173

CPC classification number: H04W28/14 ,  G06F8/62 ,  G06F11/1458 ,  G06F11/1469 ,  G06F21/6245 ,  G06F21/88 ,  G06Q10/06 ,  H04L63/20 ,  H04L67/34 ,  H04L69/40 ,  H04M3/42229 ,  H04W8/08 ,  H04W12/08 ,  H04W12/12 ,  H04W24/00 ,  H04W60/00

Abstract: A system and methods are provided for remotely recovering and purging data from a wireless device in a communications network. The system includes a wireless device capable of executing a data recovery/purge application program for receiving a message from a communications device in the network. The application program retrieves the data in the wireless device, purges the data from the wireless device, and sends a return message, including the data retrieved from the wireless device, to the communications device.

Abstract translation: 提供了一种用于从通信网络中的无线设备远程恢复和清除数据的系统和方法。 该系统包括能够执行用于从网络中的通信设备接收消息的数据恢复/清除应用程序的无线设备。 应用程序检索无线设备中的数据，从无线设备清除数据，并将包括从无线设备检索的数据的返回消息发送到通信设备。

公开(公告)号：US20100214650A1

公开(公告)日：2010-08-26

申请号：US12712902

申请日：2010-02-25

Applicant: Tony Maryfield ,  Robert Koch ,  Anand Hariharan

Inventor： Tony Maryfield ,  Robert Koch ,  Anand Hariharan

IPC: H01S3/067 ,  G02B6/036 ,  G02B6/34 ,  G02B6/42

CPC classification number: H01S3/06704 ,  G02B6/4202 ,  H01S3/06729 ,  H01S3/0675 ,  H01S3/06754 ,  H01S3/1603

Abstract: Systems and devices enabling a highly compact design for a fiber-based lasing and/or amplifying system are disclosed. In some instances, a tightly-coiled active optical fiber may be coupled with a seed source and a pump source for optical amplification and other applications. Such systems can be disposed in a small footprint package such as a butterfly package or a high heat load package. In some instances, the tightly-wound active optical fiber may further include a fiber Bragg grating adapted to accommodate bends in the active optical fiber. The active optical fiber may further utilize a cladding shaped to maintain an orientation of the active optical fiber in relation to a bend in the fiber.

Abstract translation: 公开了一种能够实现基于光纤的激光和/或放大系统的紧凑设计的系统和装置。 在一些情况下，紧密卷绕的有源光纤可以与种子源和用于光学放大和其它应用的泵浦源耦合。 这样的系统可以放置在小尺寸封装中，例如蝶形封装或高热负载封装。 在一些情况下，紧密缠绕的有源光纤还可以包括适于在有源光纤中容纳弯曲的光纤布拉格光栅。 有源光纤可以进一步利用成形的包层来保持有源光纤相对于光纤中的弯曲的取向。

公开(公告)号：US07715538B2

公开(公告)日：2010-05-11

申请号：US11390768

申请日：2006-03-28

Applicant: Robert Koch ,  Genniman Wood ,  Kevin Forsberg

Inventor： Robert Koch ,  Genniman Wood ,  Kevin Forsberg

IPC: H04M1/56

CPC classification number: H04M3/42153 ,  H04M3/436 ,  H04M3/53391 ,  H04M2203/2011 ,  H04M2203/651

Abstract: A privacy screening service allows a subscriber to send a call screening request during a telephone call. The call screening request may comprise a Dual-Tone Multi-Frequency key (e.g., “Touch Tones”) on a telephone keypad, a softkey entry on a communications device, and/or a data message from an Internet Protocol phone or client application. The call screening request may store incoming line identification (ICLID) information of the connected communications signal in a database, add the ICLID information to a Do Not Call list, update a subscriber's profile with the ICLID information, and/or storing the ICLID information in a subscriber's blocked communications list. The Do Not Call list, the subscriber's profile, and/or the subscriber's blocked communications list may include communications instructions for the called number as well as include communications instructions for other registered communications addresses (e.g., other telephone numbers, an email address, and other communications addresses of the subscriber).

Abstract translation: 隐私筛选服务允许用户在电话呼叫期间发送呼叫筛选请求。 呼叫筛选请求可以包括电话小键盘上的双音多频键（例如，“触摸音”），通信设备上的软键条目和/或来自因特网协议电话或客户端应用的数据消息。 呼叫筛选请求可以将连接的通信信号的入线标识（ICLID）信息存储在数据库中，将ICLID信息添加到不呼叫列表，使用ICLID信息更新用户简档，和/或将ICLID信息存储在 订户的阻止通信列表。 不要呼叫列表，订户的简档和/或订户的阻止的通信列表可以包括被叫号码的通信指令，并且包括用于其他注册的通信地址的通信指令（例如，其他电话号码，电子邮件地址等） 用户的通信地址）。

公开(公告)号：US07669615B2

公开(公告)日：2010-03-02

申请号：US11335133

申请日：2006-01-19

Applicant: Robert Koch

Inventor： Robert Koch

IPC: F16L11/00

CPC classification number: B60D5/003 ,  B61D17/22

Abstract: The subject matter of the invention is a fabric layer of a bellows, e.g., of a connection between two hinge-linked vehicles or of an aircraft passenger bridge, the fabric layer being plastically deformed by a force acting on the fabric.

Abstract translation: 本发明的主题是波纹管的织物层，例如两个铰链连接的车辆或飞机乘客桥之间的连接，织物层通过作用在织物上的力塑性变形。