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    Bifurcated multicapsule intraluminal grafting system
    4.
    发明授权
    Bifurcated multicapsule intraluminal grafting system 失效
    分叉多囊腔腔内植入系统

    公开(公告)号：US5824044A

    公开(公告)日：1998-10-20

    申请号：US707179

    申请日：1996-09-03

    申请人： Dinah B. Quiachon ,  Alec A. Piplani ,  Steve G. Baker ,  Ronald G. Williams ,  Richard S. Williams ,  Kenneth L. Osborn ,  Ted W. Layman ,  Peter K. Johansson

    发明人： Dinah B. Quiachon ,  Alec A. Piplani ,  Steve G. Baker ,  Ronald G. Williams ,  Richard S. Williams ,  Kenneth L. Osborn ,  Ted W. Layman ,  Peter K. Johansson

    IPC分类号： A61B17/00 ,  A61B17/11 ,  A61B19/00 ,  A61F2/00 ,  A61F2/06 ,  A61F2/88 ,  A61F11/00 ,  A61M25/12 ,  A61F2/04

    CPC分类号： A61F2/07 ,  A61F2/954 ,  A61F2/958 ,  A61B90/39 ,  A61F2/88 ,  A61F2/89 ,  A61F2002/065 ,  A61F2002/075 ,  A61F2002/8483 ,  A61F2002/8486 ,  A61F2002/9517 ,  A61F2250/0098

    摘要： An improved intraluminal grafting system incorporating novel structural features for enhancing the effective and efficient deployment of a bifurcated prosthesis having a plurality of attachment systems, in the vessel of an animal body, the system including a balloon catheter assembly, an ipsilateral capsule catheter assembly, distal and contralateral capsule assemblies and means interacting therewith, and a capsule jacket assembly. The capsule assemblies include an ipsilateral capsule assembly, a contralateral capsule assembly and a distal capsule assembly, wherein the attachment systems of the bifurcated prosthesis are disposed within the three capsule assemblies. The capsule jacket assembly includes a removable sheath that covers the bifurcated prosthesis and capsule assemblies to provide a smooth transition along the length of the deployment catheters. The bifurcated prosthesis is comprised of a main tubular member and two tubular legs, having attachment systems secured to the superior end of the main tubular member and the inferior ends of the tubular legs. An inflatable membrane configured on the balloon catheter is used to firmly implant the attachment systems within the vessel. The bifurcated prosthesis and attachment systems are configured to remain in the vessel after the deployment catheters are withdrawn. A novel method of use of the present intraluminal grafting system is also disclosed, for example, for deploying a bifurcated prosthesis proximate the abdominal aortic bifurcation.

    摘要翻译： 一种改进的腔内移植系统，其结合新颖的结构特征，用于在动物体的血管中增强有多个附着系统的分叉假体的有效和有效部署，所述系统包括气囊导管组件，同侧囊导管组件，远端 和对侧胶囊组件以及与其相互作用的装置，以及胶囊护套组件。 胶囊组件包括同侧胶囊组件，对侧胶囊组件和远端胶囊组件，其中分叉假体的附接系统设置在三个胶囊组件内。 胶囊护套组件包括可拆卸的护套，其覆盖分叉的假体和胶囊组件以沿着展开导管的长度提供平滑的过渡。 分叉的假体由主管状构件和两个管状腿组成，具有固定到主管状构件的上端和管状腿的下端的附接系统。 构造在球囊导管上的充气膜用于将附着系统牢固地植入容器内。 分叉的假体和附件系统构造成在展开导管被抽出之后保留在容器中。 还公开了一种使用本发明的管腔内接枝系统的新方法，例如用于在腹主动脉分叉附近部署分叉假体。

    Dual valve reinforced sheath and method
    6.
    发明授权
    Dual valve reinforced sheath and method 失效
    双阀增强护套和方法

    公开(公告)号：US5395349A

    公开(公告)日：1995-03-07

    申请号：US109131

    申请日：1993-08-19

    申请人： Dinah B. Quiachon ,  Wesley D. Sterman ,  Ronald G. Williams ,  David C. Dillow ,  Steven G. Baker

    发明人： Dinah B. Quiachon ,  Wesley D. Sterman ,  Ronald G. Williams ,  David C. Dillow ,  Steven G. Baker

    IPC分类号： A61B17/34 ,  A61M25/00 ,  A61M25/06 ,  A61M39/06 ,  A61M39/00

    CPC分类号： A61M25/0075 ,  A61B17/3462 ,  A61M25/005 ,  A61M25/0662 ,  A61M39/06 ,  A61M39/0613 ,  A61M2039/062 ,  A61M2039/0673 ,  A61M2039/0686 ,  A61M25/0021 ,  A61M25/0023 ,  A61M25/0053 ,  A61M25/0668

    摘要： A large-diameter expandable sheath for use in introducing a catheter or other medical instrument into a vessel in the body of a patient. The expandable sheath comprises an elongate sheath tube formed of a flexible material which has proximal and distal extremities and a passage extending therethrough of a maximum predetermined diameter. The distal extremity of the elongate sheath tube is folded longitudinally to a smaller folded diameter. The sheath tube may be self-expanding or may be reinforced with a self-expanding wire or expandable stents. A backflow adapter is secured to the proximal extremity of the elongate sheath tube. The backflow adapter has a central opening therein in registration with the passage in the sheath tube. A normally closed primary valve is disposed in the central opening of the backflow adapter and is movable to an open position. A normally open secondary valve, movable to a closed position, may be configured in the backflow adapter proximal the sheath tube and distal the primary valve. The primary and secondary valves when open permit a catheter or other medical instrument to be inserted into the sheath, and when closed form a hemostatic seal about the catheter. A sheath introducer is provided for guiding the distal end of the sheath tube into a vessel and is configured to be positioned within the backflow adapter.

    摘要翻译： 用于将导管或其他医疗器械引入患者体内的容器中的大直径可扩张护套。 可膨胀护套包括由柔性材料形成的细长护套管，该护套管具有近端和远端以及延伸穿过其中的最大预定直径的通道。 细长护套管的远端被纵向折叠成较小的折叠直径。 鞘管可以是自膨胀的，或者可以用自膨胀丝或可扩张的支架来增强。 回流适配器固定到细长护套管的近端。 回流适配器具有与护套管中的通道对准的中心开口。 常闭主阀设置在回流适配器的中心开口中并且可移动到打开位置。 能够移动到关闭位置的常开二次阀可以构造在靠近护套管的回流适配器中并且远离主阀。 打开时的主要和次要阀允许导管或其他医疗器械插入护套中，并且当关闭时形成围绕导管的止血密封。 提供护套导引器用于将护套管的远端引导到容器中并且构造成定位在回流适配器内。

    Apparatus, system and method for measuring spatial average velocity and/or volumetric flow of blood in a vessel
    8.
    发明授权
    Apparatus, system and method for measuring spatial average velocity and/or volumetric flow of blood in a vessel 失效
    用于测量血管中血液的空间平均速度和/或体积流量的装置，系统和方法

    公开(公告)号：US4967753A

    公开(公告)日：1990-11-06

    申请号：US297111

    申请日：1989-01-13

    申请人： Wayne C. Haase ,  Jerome Segal ,  Paul D. Corl ,  Jeffrey J. Christian ,  Ronald G. Williams

    发明人： Wayne C. Haase ,  Jerome Segal ,  Paul D. Corl ,  Jeffrey J. Christian ,  Ronald G. Williams

    IPC分类号： A61B8/06 ,  G01F1/66

    CPC分类号： A61B8/06 ,  A61B8/12 ,  A61B8/445 ,  G01F1/663 ,  A61M2025/09175

    摘要： System for measuring a characteristic of flow of liquid in a vessel of a patient comprising a transducer positioned in a vessel in a patient for supplying ultrasonic energy. The transducer produces a substantially uniform beam which encompasses the vessel. The transducer receives ultrasonic energy back scattered from the red blood cells and provides an electrical output signal. A first moment detector is provided which receives the electrical output from the transducer and provides a first moment signal. Normalization is provided to the output of the first moment detector to provide an electrical output representing a characteristic of the flow of the liquid in the vessel.

    摘要翻译： 用于测量患者容器中液体流动特性的系统，包括位于病人容器中的换能器，用于提供超声能量。 换能器产生包围血管的基本均匀的束。 传感器接收从红细胞反向散射的超声能量，并提供电输出信号。 提供了第一时刻检测器，其接收来自换能器的电输出并提供第一力矩信号。 将标准化提供给第一力矩检测器的输出，以提供表示容器中液体流动的特性的电输出。

    Apparatus and method for controlled removal of stenotic material from stents
    9.
    发明授权
    Apparatus and method for controlled removal of stenotic material from stents 失效
    从支架中控制切除狭窄材料的装置和方法

    公开(公告)号：US06319242B1

    公开(公告)日：2001-11-20

    申请号：US09260935

    申请日：1999-03-02

    申请人： Greg R. Patterson ,  Ronald G. Williams ,  James J. Leary

    发明人： Greg R. Patterson ,  Ronald G. Williams ,  James J. Leary

    IPC分类号： A61M3100

    CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B2017/00026 ,  A61B2017/00119 ,  A61B2017/2212 ,  A61B2090/378 ,  A61B2217/005 ,  A61F2/82

    摘要： Apparatus and methods for treating in-stent restenosis are described for removing stenotic material from within previously stented regions of a patient's vasculature. The apparatus includes a catheter system having a stenotic material removal mechanism mounted on a distal portion of an elongated inner catheter. A sensing means, such as one or more sensing electrodes, are positioned on an outer surface of the apparatus. In addition, the apparatus optionally includes control means for diametrically expanding the stenotic material removal mechanism for effective recanalization of the stent. A coaxial outer catheter is provided for aspirating stenotic material which is removed from within the stent. In addition, embolic filter apparatus are described for collecting the stenotic material removed from within the stent. The methods comprise operating the stenotic material removal mechanism within a body vessel, typically a coronary artery or other artery, which has become restenosed or otherwise occluded following the initial stent placement, and sensing the proximity or contact between the stenotic material removal mechanism and the stent within the arterial wall so that the stenosis can be effectively recanalized without damaging the stent. The sensing means may be used to indicate an unsafe condition that might lead to stent damage, in response to which, the stenotic material removal mechanism may be manually or automatically deactivated. Alternatively or additionally, the sensing means may be used to indicate an appropriate endpoint for the stenotic material removal process.

    摘要翻译： 描述了用于治疗支架内再狭窄的装置和方法，用于从患者脉管系统的先前支架区域内移除狭窄材料。 该装置包括具有安装在细长内导管的远端部分上的狭窄材料去除机构的导管系统。 诸如一个或多个感测电极的感测装置位于装置的外表面上。 此外，该装置还可选择地包括用于直径地扩张狭窄材料去除机构以控制支架有效再通的控制装置。 提供同轴的外导管用于吸入从支架内移除的狭窄材料。 此外，描述了用于收集从支架内移除的狭窄材料的栓塞过滤装置。 所述方法包括在主体容器（通常是冠状动脉或其他动脉）中操作狭窄材料去除机构，所述冠状动脉或其它动脉在初始支架放置之后已经被再次闭合或者被封闭，并且感测狭窄材料移除机构和支架之间的接近或接触 在动脉壁内，使得狭窄可以有效再通，而不会损伤支架。 感测装置可以用于指示可能导致支架损伤的不安全状态，响应于此，可以手动或自动停用狭窄材料去除机构。 或者或另外，感测装置可以用于指示用于狭窄材料去除过程的适当端点。

    Vascular stent for reduction of restenosis
    10.
    发明授权
    Vascular stent for reduction of restenosis 失效
    用于减少再狭窄的血管支架

    公开(公告)号：US6165209A

    公开(公告)日：2000-12-26

    申请号：US209233

    申请日：1998-12-10

    申请人： Greg R. Patterson ,  David J. Kupiecki ,  Kathy M. Mah ,  Ronald G. Williams ,  James J. Leary

    发明人： Greg R. Patterson ,  David J. Kupiecki ,  Kathy M. Mah ,  Ronald G. Williams ,  James J. Leary

    IPC分类号： A61F2/90 ,  A61F2/06

    CPC分类号： A61F2/915 ,  A61F2/90 ,  A61F2/91 ,  A61F2/95 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2220/005

    摘要： Apparatus and methods are provided for restoring and maintaining an open passage or lumen in a body conduit, such as a blood vessel, which has become stenosed or occluded. The apparatus includes a stent which is specially adapted for inhibiting restenosis within the stent after implantation in a body passage. In various embodiments, the apparatus also includes a catheter or other device for operating the stent to inhibit restenosis within the stented region of the body passage. The methods presented include implanting the stent within a body passage, typically a blood vessel such as a coronary artery, which has become stenosed or occluded, and operating the stent to inhibit ingrowth of stenotic material which would result in restenosis of the stented region. The stent may be operated manually to inhibit or remove ingrowth of stenotic material, for example by introducing a catheter which acts on the stent, or the stent may operate automatically to inhibit or remove ingrowth of stenotic material without manual intervention.

    摘要翻译： 提供了用于恢复和维持已经变得狭窄或闭塞的体导管（例如血管）中的开放通道或内腔的装置和方法。 该装置包括一种支架，其特别适用于在植入人体通道之后抑制支架内的再狭窄。 在各种实施例中，该装置还包括用于操作支架的导管或其他装置，以抑制身体通道的支架区域内的再狭窄。 所提出的方法包括将支架植入人体通道内，通常是已经变得狭窄或闭塞的冠状动脉血管如冠状动脉，以及操作支架以抑制狭窄材料的向内生长，这将导致支架区域的再狭窄。 可以手动操作支架以抑制或消除狭窄材料的向内生长，例如通过引入作用在支架上的导管，或者支架可以自动操作以抑制或消除狭窄材料的向内生长而无需手动干预。