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公开(公告)号：US20180252677A1
公开(公告)日：2018-09-06
申请号：US15960542
申请日：2018-04-23
IPC分类号： G01N27/48 , G01N27/327 , C23C14/02 , C23C14/20 , C23C14/58 , C23C14/34 , G03F7/20 , G01N33/483
CPC分类号： G01N27/48 , A61B5/1473 , C23C14/0005 , C23C14/022 , C23C14/205 , C23C14/3464 , C23C14/5806 , C23C14/5846 , C25B1/02 , C25B9/06 , C25B11/0405 , C25B11/0415 , C25B11/0478 , G01N27/327 , G01N33/4833 , G01N33/49 , G03F7/70
摘要： A method for cancer diagnosis is disclosed. The method includes forming a plurality of cultured cells on an electrochemical biosensor placing the electrochemical biosensor in a medium solution comprising a cell culture solution of a plurality of biological cells, measuring a first electrochemical response from the electrochemical biosensor with the plurality of cultured cells, forming a plurality of stimulated cells on the electrochemical biosensor by ultrasonically stimulating of the plurality of cultured cells, measuring a second electrochemical response from the electrochemical biosensor with the plurality of stimulated cells, and detecting presence of cancer cells responsive to a difference between the first electrochemical response and the second electrochemical response being less than a threshold. Where, the first electrochemical response includes an electrochemical response of the plurality of cultured cells and the second electrochemical response includes an electrochemical response of the plurality of stimulated cells.
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公开(公告)号：US11079355B2
公开(公告)日：2021-08-03
申请号：US15960542
申请日：2018-04-23
IPC分类号： G01N27/48 , G01N27/327 , G01N33/483 , C23C14/02 , C23C14/58 , C23C14/34 , G03F7/20 , C23C14/20 , C25B9/17 , C25B11/051 , C25B11/057 , C25B11/091 , A61B5/1473 , C23C14/00 , C25B1/02 , G01N33/49
摘要： A method for cancer diagnosis is disclosed. The method includes forming a plurality of cultured cells on an electrochemical biosensor placing the electrochemical biosensor in a medium solution comprising a cell culture solution of a plurality of biological cells, measuring a first electrochemical response from the electrochemical biosensor with the plurality of cultured cells, forming a plurality of stimulated cells on the electrochemical biosensor by ultrasonically stimulating of the plurality of cultured cells, measuring a second electrochemical response from the electrochemical biosensor with the plurality of stimulated cells, and detecting presence of cancer cells responsive to a difference between the first electrochemical response and the second electrochemical response being less than a threshold. Where, the first electrochemical response includes an electrochemical response of the plurality of cultured cells and the second electrochemical response includes an electrochemical response of the plurality of stimulated cells.
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