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公开(公告)号：US07438700B2
公开(公告)日：2008-10-21
申请号：US10792575
申请日：2004-03-04
Applicant: Kazunori Ishizeki , Hisatomo Ohki , Shigemi Nakamura , Akira Yanagawa
Inventor： Kazunori Ishizeki , Hisatomo Ohki , Shigemi Nakamura , Akira Yanagawa
IPC: A61M13/00
CPC classification number: B05B11/062 , A61M15/08 , A61M16/208 , A61M2202/064 , A61M2205/075
Abstract: A medicine administering device for nasal cavities of a patient suffering from nasal allergy or the like. The medicine administering device comprises a medicine administering device main body including a part defining a powdery medicine accommodating chamber, and a spray nozzle located at a tip end side of the main body. A pump is disposed at a base end side of the medicine administering device main body to discharge air within the pump through the powdery medicine accommodating chamber to the spray nozzle upon being pressed from an outside of the pump. Additionally, a restricting device is disposed within the pump to restrict a displacement amount of the pump in accordance with first and second kinds of pressing positions at which the pump is pressed. The first and second kinds of pressing positions lie respectively in first and second directions which are perpendicular to each other.
Abstract translation: 用于患有鼻过敏等的患者的鼻腔的给药装置。 给药装置包括：给药装置主体，包括限定粉末药剂容纳室的部分和位于主体的前端侧的喷嘴。 泵在配药装置主体的基端侧配置，从泵的外侧按压时，将泵内的空气从粉末药剂收容室排出到喷雾嘴。 此外，限制装置设置在泵内，以根据泵被按压的第一和第二种按压位置来限制泵的位移量。 第一和第二种按压位置分别位于彼此垂直的第一和第二方向上。
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公开(公告)号：US20050048003A1
公开(公告)日：2005-03-03
申请号：US10960575
申请日：2004-10-08
Applicant: Hisatomo Ohki , Shigemi Nakamura , Kazunori Ishizeki , Yoshiyuki Yazawa , Akira Yanagawa
Inventor： Hisatomo Ohki , Shigemi Nakamura , Kazunori Ishizeki , Yoshiyuki Yazawa , Akira Yanagawa
CPC classification number: A61M15/0045 , A61M11/002 , A61M15/0033 , A61M15/0035 , A61M15/0048 , A61M2202/064 , A61M2206/16
Abstract: A blister pack for an inhalant medicator has a plurality of medical powder storage chambers spaced apart from each other in a circumferential direction. The inhalant medicator includes a pricking tool with a pair of parallel pins that prick inflow and outflow holes in one of the medical powder storage chambers during a preliminary operation of inhalant medication. The inflow and outflow holes are spaced apart from each other by a predetermined distance in a direction parallel to a lid panel of the blister pack to produce turbulent airflow within the medical powder storage chamber during inhalation during which the medical powder is inhaled by a patient's breathing. The medical powder storage chambers are dimensioned and designed to properly regulate or control properties of the airflow passing through the medical storage chamber, to ensure the airflow is suitable for the medical powder stored in the storage chamber.
Abstract translation: 用于吸入剂的泡罩包装体具有沿圆周方向彼此隔开的多个医用粉末储存室。 吸入剂包括具有一对平行销的穿刺工具，其在吸入药物的初步操作期间刺入一个医疗粉末储存室中的流入和流出孔。 流入和流出孔在平行于泡罩包装的盖板的方向上彼此隔开预定距离，以在吸入期间在医用粉末储存室内产生湍流气流，在此期间医疗粉末被患者的呼吸吸入 。 医疗粉末储存室的尺寸设计成适当地调节或控制通过医疗储存室的气流的特性，以确保气流适用于存储在储存室中的医用粉末。
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公开(公告)号：US06595210B2
公开(公告)日：2003-07-22
申请号：US09908915
申请日：2001-07-20
Applicant: Hisatomo Ohki , Yoshiyuki Yazawa , Shigemi Nakamura , Mitsuru Yokobori , Kazunori Ishizeki
Inventor： Hisatomo Ohki , Yoshiyuki Yazawa , Shigemi Nakamura , Mitsuru Yokobori , Kazunori Ishizeki
IPC: A61M1300
CPC classification number: A61M15/0028 , A61M11/001 , A61M15/003 , A61M15/0033 , A61M2202/064 , A61M2206/16
Abstract: An inhalator including an inhalator body including a powder receiving chamber for receiving a powder, an air-powder mixture reservoir for temporarily storing an air-powder mixture flowing from the powder receiving chamber, and a diluent air passage for introducing a diluent air into the air-powder mixture reservoir. The air-powder mixture is formed within the powder receiving chamber when an air is introduced into the powder receiving chamber. The air-powder mixture within the air-powder mixture reservoir is admixed with a diluent air introduced thereinto through the diluent air passage. The diluted air-powder mixture is discharged from an air-powder mixture outlet into a user's oral or nasal cavity. A powder composition for inhalators includes at least two kinds of fine particles different in particle diameter.
Abstract translation: 一种吸入器，包括：吸入器主体，包括用于接收粉末的粉末接收室;用于临时存储从粉末接收室流出的空气 - 粉末混合物的空气 - 粉末混合物储存器;以及用于将稀释空气引入空气的稀释空气通道 粉末混合物储层。 当空气被引入到粉末接收室中时，空气 - 粉末混合物形成在粉末接收室内。 将空气 - 粉末混合物储存器内的空气 - 粉末混合物与通过稀释剂空气通道引入的稀释空气混合。 稀释的空气 - 粉末混合物从空气 - 粉末混合物出口排出到用户的口腔或鼻腔中。 用于吸入器的粉末组合物包括至少两种粒径不同的细颗粒。
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公开(公告)号：US5921236A
公开(公告)日：1999-07-13
申请号：US727633
申请日：1996-11-01
Applicant: Hisatomo Ohki , Shigemi Nakamura , Kazunori Ishizeki , Akira Yanagawa
Inventor： Hisatomo Ohki , Shigemi Nakamura , Kazunori Ishizeki , Akira Yanagawa
CPC classification number: A61M15/0028 , A61M15/0033 , A61M2202/064 , A61M2205/071 , A61M2205/075
Abstract: A capsule holder 2 of a medicine administering device 1 for nasal cavities comprises a movable member 8 which is axially movable, and a fixed member 3, in which the movable member 8 is formed at its outer periphery with an external thread 8D which is to be threadedly engaged with an internal thread 19C of a medicine spraying section 19. An air inflow hole H is formed by a perforating end 27A of a pin 27 when a capsule K is thrust into a one-side capsule hole 11, while the movable member 8 is raised so that the perforating end 27A is extracted from the air inflow hole H1 when the capsule holder 2 and the medicine spraying section 19 are incorporated with each other. An air outflow hole H2 is formed by a pin 28. A perforating tool is housed in the medicine administering device 1, in which a hole formation action for the air inflow hole H1 is also made during installation of the capsule K. The whole body can be made compact since the longitudinal dimension of the pin 27, 28 is decreased while the outer peripheral surface of the capsule holder 2 is covered with a pump section 15.
Abstract translation: PCT No.PCT / JP96 / 00596 Sec。 371日期：1996年11月1日 102（e）1996年11月1日PCT PCT 1996年3月11日PCT公布。 公开号WO96 / 29109 日期1996年9月26日用于鼻腔的给药装置1的胶囊保持器2包括可轴向移动的可动构件8和固定构件3，其中可动构件8在其外周形成有外螺纹 8D，其与药物喷射部19的内螺纹19C螺纹接合。当胶囊K被推入单侧胶囊孔11中时，空气流入孔H由销27的穿孔端27A形成， 同时使可动构件8升高，使得当胶囊保持器2和药物喷射部19彼此结合时，穿孔端部27A从空气流入孔H1抽出。 空气流出孔H2由销28形成。射出工具被容纳在给药装置1中，其中在安装胶囊K期间也进行用于空气流入孔H1的孔形成作用。整体可以 由于销27,28的纵向尺寸减小，同时胶囊保持器2的外周表面被泵部分15覆盖，因此可以紧凑。
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公开(公告)号：US5752505A
公开(公告)日：1998-05-19
申请号：US820654
申请日：1997-03-18
Applicant: Hisatomo Ohki , Shigemi Nakamura , Kazunori Ishizeki , Yoshiyuki Yazawa , Akira Yanagawa
Inventor： Hisatomo Ohki , Shigemi Nakamura , Kazunori Ishizeki , Yoshiyuki Yazawa , Akira Yanagawa
CPC classification number: A61M15/0028 , A61M15/0015 , A61M15/0036 , A61M2202/064
Abstract: An inhalation type medication delivery device includes a dispenser body having a powder containment chamber at one axial side thereof and an inhalation port for drawing in a powder type medication on the another. An attached lid is provided on the dispenser body for opening and/or closing the powder containment chamber. In addition, an air passage is defined in the body allowing a powder type medication to be introduced into an airflow toward the inhalation port according to inhalation by a user. One end of the air passage opens through the lid towards the outside atmosphere and the other end communicates with the inhalation port while passing through the powder containment chamber. Also, a check valve is installed in the lid to prevent air drawn into said inhalation port from flowing in an outward direction opposite a medication delivery direction toward the inhalation port. Additional efficiency may be achieved by further providing a supplementary passage communicating between the inhalation port and the outside atmosphere independently of the air passage to generate additional suction force during inhalation.
Abstract translation: 吸入型药物输送装置包括：分配器本体，其具有在其一个轴向侧的粉末容纳室和用于吸入粉末型药物的吸入口。 在分配器主体上设置附接的盖，用于打开和/或关闭粉末容纳室。 此外，空气通道被限定在体内，允许粉末型药物根据使用者的吸入被引入朝向吸入口的气流中。 空气通道的一端通过盖朝向外部大气开放，另一端在通过粉末容纳室的同时与吸入口连通。 此外，止回阀安装在盖中，以防止吸入所述吸入口的空气朝向与吸入口相反的药物输送方向的向外方向流动。 通过进一步提供在吸入口和外部气氛之间连通的补充通道，可独立于空气通道来实现额外的效率，以在吸入期间产生额外的吸力。
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Patent Agency Ranking
公开(公告)号：US5715811A
公开(公告)日：1998-02-10
申请号：US537862
申请日：1996-01-22
Applicant: Hisatomo Ohki , Atsuo Wakayama , Shigemi Nakamura , Kazunori Ishizeki , Akira Yanagawa
Inventor： Hisatomo Ohki , Atsuo Wakayama , Shigemi Nakamura , Kazunori Ishizeki , Akira Yanagawa
CPC classification number: A61M15/0028 , A61M15/0033 , A61M2202/064
Abstract: An inhaling piece 1 is formed with an inhaling mouth 3 and a holder accommodating section 2. A capsule holder 6 is formed with a capsule accommodating hole 7 and air flow passages 8, 8 which extend axially, and is further formed with pin insertion holes 10, 11 which extend diametrically and are in communication with these air flow passages 8. When a capsule 17 is accommodated in the capsule accommodating hole 7 and the pins 16 are inserted into the pin insertion holes 10, 11, through-holes H, H, . . . are formed in the capsule 17. When the patient intends to inhale medicine, inhaling is made by first returning the pins 16 to the inhaling piece 1 so that the medicine can be securely and effectively carried to the lungs of the patient under the action of air flow.
Abstract translation: PCT No.PCT / JP95 / 01007 Sec。 371日期1996年1月22日 102（e）日期1996年1月22日PCT提交1995年5月25日PCT公布。 WO95 / 32751 PCT出版物 日期1995年12月7日吸气片1形成有吸入口3和保持器容纳部2.胶囊保持器6形成有胶囊容纳孔7和沿轴向延伸的气流通道8,8，并且进一步形成 具有插销孔10,11，其直径延伸并且与这些气流通道8连通。当胶囊17容纳在胶囊容纳孔7中并且销16插入销插入孔10,11， 孔H，H，。 。 。 形成在胶囊17中。当患者意图吸入药物时，通过首先将销16返回到吸入件1来进行吸入，使得药物可以在空气的作用下牢固有效地携带到患者的肺部 流。
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公开(公告)号：US20120328221A1
公开(公告)日：2012-12-27
申请号：US13520933
申请日：2011-01-06
Applicant: Nobuyuki Maki , Fukuji Nakano , Shigemi Nakamura
Inventor： Nobuyuki Maki , Fukuji Nakano , Shigemi Nakamura
CPC classification number: F16C29/065 , F16C33/6681 , Y10T29/49641
Abstract: A motion guide device has a moving block mounting surface 501 of an end plate 5 formed in a planar shape and a thinned-down portion 52 formed in an opposing moving block mounting surface 502. Moreover, in this motion guide device, a lubrication path 30 includes: a first lubrication path 30a formed extending in a horizontal direction from a surface of side surfaces parallel to a longer direction of a track rail 1 in the end plate 5 to a central portion of the end plate 5; a second lubrication path 30b formed in the central portion of the end plate 5; and a third lubrication path 30c connected to the second lubrication path and formed in a groove shape in the moving block mounting surface 501 of the end plate 5, and, moreover, the first lubrication path 30a is formed in a hollow shape continuous to inside a built-up portion 52a appended to the thinned-down portion 52 of the end plate 5. Having such a configuration enables this motion guide device to achieve an average dispersal of lubricant to each of rolling element circulation paths regardless of mounting position of a greasing nipple with respect to the end plate, type of lubricant, and so on.
Abstract translation: 运动引导装置具有形成为平面形状的端板5的移动块安装面501和形成在相对移动块安装面502中的减薄部52.另外，在该运动引导装置中，具有润滑路径30 包括：从端板5中的平行于轨道轨道1的较长方向的侧面的水平方向形成的端部板5的中央部形成的第一润滑路径30a; 形成在端板5的中心部分的第二润滑通路30b; 以及连接到第二润滑路径并在端板5的移动块安装表面501中形成为凹槽形状的第三润滑路径30c，此外，第一润滑路径30a形成为连续到内侧的中空形状 构成部分52a附加到端板5的减薄部分52上。具有这种构造使得该运动引导装置能够实现润滑剂到滚动体循环路径中的平均分散，而与润滑乳头的安装位置无关 相对于端板，润滑剂的类型等。
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公开(公告)号：US08181647B2
公开(公告)日：2012-05-22
申请号：US11448754
申请日：2006-06-08
Applicant: Kazunori Ishizeki , Hisatomo Ohki , Shigemi Nakamura , Akira Yanagawa
Inventor： Kazunori Ishizeki , Hisatomo Ohki , Shigemi Nakamura , Akira Yanagawa
CPC classification number: A61M15/0065 , A61M11/02 , A61M2202/064
Abstract: A powder medicine administering device includes a main body, an air supply section, and a movable member slidably attached to the main body, and arranged to be moved relative to the main body from a first position through a second position to a third position. One of the main body and the movable member includes a side wall portion defining a medicine storage chamber including an opening closed by a sliding surface of the other of the main body and the movable member at the second position of the movable member, and a medicine discharge passage. The other of the main body and the movable member is formed with a medicine carrying chamber connected with the opening of the medicine storage chamber at the first position of the movable member, and connected with the medicine discharge passage at the third position of the movable member.
Abstract translation: 粉末给药装置包括主体，供气部分和可滑动地附接到主体的可移动部件，并且被布置成相对于主体从第一位置移动到第二位置到第三位置。 主体和可动部件中的一个包括限定药剂储存室的侧壁部，该药剂收容室具有由可动部件的第二位置处的主体和可动部件的另一方的滑动面封闭的开口， 排放通道。 主体和可动部件中的另一个形成有与药剂容纳室的开口连接的可动部件的第一位置的药剂传送室，与可动部件的第三位置处的药液排出通路连接 。
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公开(公告)号：US20070017511A1
公开(公告)日：2007-01-25
申请号：US10557358
申请日：2004-05-14
Applicant: Hisatomo Ohki , Shigemi Nakamura , Kazunori Ishizeki , Akira Yanagawa
Inventor： Hisatomo Ohki , Shigemi Nakamura , Kazunori Ishizeki , Akira Yanagawa
CPC classification number: A61M15/0028
Abstract: Medicine powder is prevented from adhering to the tongue and the like when the medicine powder is being inhaled, discomfort due to the sense of taste is relieved, and a prescribed amount of medicine powder is enabled to be administered efficiently. With regard to a long mouthpiece 16, the length L of its held-in-the-mouth area 16C to be held in the mouth 19 is set at approximately 80 mm. This enables one end of the held-in-the-mouth area 16C to be inserted deep into the oral cavity 22 when the held-in-the-mouth 16C is held in the mouth 19. Accordingly, the medicine powder can be discharged in a position beyond sweetness sensing parts 24A, saltiness sensing parts 24B, sourness sensing parts 24C and bitterness sensing parts 24D of the tongue 24. Thereby, a patient can inhale the medicine powder comfortably without sensing bitterness, sourness, sweetness and the like of the medicine powder. In addition, the held-in-the-mouth area 16C of the long mouthpiece 16 can press down the tongue 24, thus enabling the medicine powder to be prevented from adhering to the tongue and the like.
Abstract translation: 当药物粉末被吸入时，防止药粉附着在舌头等上，消除了由于味觉引起的不适，能够有效地施用规定量的药粉。 关于长嘴16，要保持在口19中的其保持在口腔区域16C的长度L被设定为大约80mm。 当保持在口部16C被保持在口部19中时，这使得保持在口腔区域16C的一端能够深入到口腔22中。 因此，药物粉末可以在舌头24的甜度感测部件24A，咸味感测部件24B，酸感感部件24C和苦味感测部件24D之外的位置排出。 因此，患者可以舒适地吸入药粉，而不会感觉到药粉的苦味，酸味，甜味等。 此外，长嘴16的保持口区域16C可以向下按压舌部24，从而能够防止药粉附着在舌头等上。
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公开(公告)号：US20060254585A1
公开(公告)日：2006-11-16
申请号：US11433578
申请日：2006-05-15
Applicant: Kazunori Ishizeki , Hisatomo Ohki , Shigemi Nakamura , Akira Yanagawa
Inventor： Kazunori Ishizeki , Hisatomo Ohki , Shigemi Nakamura , Akira Yanagawa
CPC classification number: A61M15/08 , A61M11/02 , A61M15/0028 , A61M15/0043 , A61M15/0045 , A61M2202/064 , A61M2205/075 , A61M2206/16 , A61M2209/06 , A61M2210/0618
Abstract: A powder medicine administering device includes a main body formed with a powder medicine discharge passage for discharging a powder medicine, and a nozzle member removably attached to the main body, and formed with a nozzle passage connected with the powder medicine discharge passage of the main body, and arranged to receive the powder medicine in a closed state. The nozzle member is arranged to be changed from the closed state to an opened state when the nozzle member is attached to the main body, to discharge the powder medicine received in the nozzle passage.
Abstract translation: 一种粉末给药装置，包括：主体，形成有用于排出粉末药物的粉末药物排出通道;以及喷嘴构件，其可移除地附接到主体，并且形成有与主体的粉末药物排放通道相连接的喷嘴通道 并且被布置成在关闭状态下接收粉末药物。 喷嘴构件被布置成当喷嘴构件附接到主体时将其从关闭状态改变到打开状态，以排出在喷嘴通道中接收的粉末药物。
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