-
1.发明授权Process for cultivating adhesive cells in a packed bed of solid cell matrix 失效在固体电池基体的填充床中培养粘合剂细胞的方法
公开(公告)号：US5260211A
公开(公告)日：1993-11-09
申请号：US617644
申请日：1990-11-26
摘要： A process and system for cultivating adhesive cells in a packed bed of solid cell matrix is disclosed. Adhesive cells are adhered to a solid cell matrix, preferably ceramic particles, and packed in a cell culture tank to form the packed bed. The culture medium is circulated through the packed bed in a direction. The circulating of the culture medium is then stopped and the direction of the medium being circulated is reversed. This periodic switching of the direction of the culture medium reduces channelling of the culture medium. The bottom or head of the culture tank can also contain a separator to trap any bubble existing in the culture medium or to trap any quantity of cell matrix possibly running out from the culture tank.
-
2.发明授权Nonwoven fabric coated with a mixture of silk fibroin, gelatin and insolubilized chitosan for use as a carrier for animal cells 失效涂有丝素蛋白，明胶和不溶性壳聚糖混合物的无纺布，用作动物细胞的载体
公开(公告)号：US5385836A
公开(公告)日：1995-01-31
申请号：US885140
申请日：1992-05-18
CPC分类号： C12N11/02 , C12N11/10 , C12N5/0068 , C12N2533/40 , C12N2533/50 , C12N2533/54 , C12N2533/72
摘要： A carrier for adhering animal cells during culturing or for immobilization of animal cells is produced by coating a porous substrate with a cell adhesive material in the form of a mixture with chitosan. In a preferred embodiment, the porous substrate is a nonwoven fabric prepared by impregnating a nonwoven fabric web with a binder resin, and the mixture contains silk fibroin, gelatin and chitosan. Coating is carried out by contacting the nonwoven fabric with a solution prepared by adding silk fibroin and gelatin to an acidic aqueous solution of chitosan to coat the nonwoven fabric, drying the coated nonwoven fabric and treating the dried nonwoven fabric with an alkali to render the chitosan insoluble.
摘要翻译： 通过用壳聚糖与混合物形式的细胞粘合剂材料涂覆多孔基材来制备用于在培养或固定动物细胞期间粘附动物细胞的载体。 在优选实施方案中，多孔基材是通过用粘合剂树脂浸渍非织造织物网而制备的无纺布，并且该混合物含有丝素蛋白，明胶和壳聚糖。 通过使非织造布与通过将丝素蛋白和明胶加入到壳聚糖的酸性水溶液中而制备的溶液进行涂布，以涂布无纺布，干燥涂布的无纺布并用碱处理干燥的无纺织物以使壳聚糖 不溶。
-
3.发明授权Human derived glycoprotein, biologically active factor which includes glycoprotein and pharmaceutical product 失效人源性糖蛋白，包括糖蛋白和药物产品的生物活性因子
公开(公告)号：US5587359A
公开(公告)日：1996-12-24
申请号：US304419
申请日：1994-09-12
IPC分类号： C12N15/00 , A61K38/00 , C07K14/475 , C07K14/52 , C12N15/09 , C12N15/19 , C12P21/02 , C07H17/00 , A01N37/00
CPC分类号： C07K14/4753 , C07K14/475 , A61K38/00
摘要： The new glycoprotein, which possesses an anti-tumor activity, a leukemia cell differentiation inducing activity, a cellular immunology enhancing activity, a vascular endothelial cell growth stimulating activity and a hepatocyte growth stimulating activity, can be obtained.
摘要翻译： 可以获得具有抗肿瘤活性，白血病细胞分化诱导活性，细胞免疫增强活性，血管内皮细胞生长刺激活性和肝细胞生长刺激活性的新糖蛋白。
-
公开(公告)号：US5079161A
公开(公告)日：1992-01-07
申请号：US370028
申请日：1989-06-22
IPC分类号： C12M3/02
CPC分类号： C12M27/02 , C12M25/16 , C12M27/22 , Y10S435/819
摘要： Cell cultivation is carried out by proliferating cells in a small preliminary culture tank containing immobilizing carriers, stripping proliferated cells from the carriers, forming a cell suspension of the stripped cells in culture medium in an intermediate reservoir, intermittently transferring the suspension into a main culture tank containing ceramic immobilizing carriers and further culturing the cells. The main culture tank has an inversed funnel-shaped inlet above the carriers with a perforated plate attached to the bottom of the inlet for uniform distribution of cell suspension from above the carriers, and a plate in the form of a net under the carriers on a perforated plate for uniform distribution of cell suspension from beneath the carriers. The main tank additionally has a lid detachably carrying the inversed funnel-shaped inlet an intermediate drum-shaped portion from which the lid is detachable and a lower portion detachably carrying the plate in the form of a net and being detachable from the drum-shaped portion. The lower portion is held on or separated from the drum-shaped portion by means of a link mechanism and a cylinder capable of lowering the lower portion to separate it from the drum-shaped portion.
-
5.发明授权公开(公告)号：US06333309B1
公开(公告)日：2001-12-25
申请号：US08617621
申请日：1996-03-19
IPC分类号： A61K746
CPC分类号： C07K14/4753 , A61K38/00 , C07K14/475
摘要： The new glycoprotein, which possesses an anti-tumor activity, a leukemia cell differentiation inducing activity, a cellular immunology enhancing activity, a vascular endothelial cell growth stimulating activity and a hepatocyte growth stimulating activity, can be obtained.
摘要翻译： 可以获得具有抗肿瘤活性，白血病细胞分化诱导活性，细胞免疫增强活性，血管内皮细胞生长刺激活性和肝细胞生长刺激活性的新糖蛋白。
-
-
-
-
搜索结果
5 条记录 (耗时 0.011 秒)
