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    SAMPLE HOLDER WITH MATRIX LAYER
    3.
    发明公开
    SAMPLE HOLDER WITH MATRIX LAYER 审中-公开

    公开(公告)号：US20240230535A1

    公开(公告)日：2024-07-11

    申请号：US18560306

    申请日：2022-05-10

    申请人： Single Technologies AB

    发明人： Bengt Sahlgren ,  Johan Strömqvist

    IPC分类号： G01N21/64 ,  G01N21/03

    CPC分类号： G01N21/6458 ,  G01N21/0332 ,  G01N2021/0325 ,  G01N2021/6482 ,  G01N2201/0415

    摘要： A sample holder (100) for an apparatus (300) configured to perform an assay at a plurality of sample sites (130) is disclosed, wherein each sample site comprises a concatemer. The sample holder comprises a rotatable body (110), a matrix layer (120) and a liquid layer arranged on the matrix layer. The plurality of samples sites are distributed in the matrix layer in both a lateral direction and a thickness direction of the matrix layer, and the rotatable body is configured to be arranged in the apparatus to be rotatable around an axis (A) while the assay is performed at the plurality of sample sites. A corresponding method (200) and apparatus (300) are also disclosed.

    Method and device for high throughput imaging
    4.
    发明授权
    Method and device for high throughput imaging 有权

    公开(公告)号：US10732113B2

    公开(公告)日：2020-08-04

    申请号：US16079900

    申请日：2017-02-23

    申请人： Single Technologies AB

    发明人： Raoul Stubbe ,  Bengt Sahlgren ,  Johan Strömqvist

    IPC分类号： G01N21/64 ,  G02B21/00 ,  G02B21/26 ,  G02B21/33 ,  G02B19/00 ,  G02B27/10 ,  G02B27/14 ,  G01N21/47 ,  G01N21/51

    摘要： An apparatus for imaging a includes an light source for illuminating the sample simultaneously in a line focus or an array of foci; and a sensor for detecting photons emitted or scattered from the sample simultaneously in an array of fields of view. An array of sub-observation volumes in the sample, from which photons are emitted or scattered during imaging, is defined by the volumes in space where the line focus or array of foci from the light source overlap with the corresponding array of field of views of the sensor. A cylindrical sample holder holds the sample at a surface and is rotatably arranged such that at least a portion of the sample can be transported through at least one of the sub-observation volumes by rotating the sample holder. The apparatus can be used in a high-throughput method of imaging.