公开(公告)号：US08124844B2

公开(公告)日：2012-02-28

申请号：US11980366

申请日：2007-10-31

申请人： Thomas J. La Rosa ,  David K. Kovalic ,  Yihua Zhou ,  Yongwei Cao ,  Mark S. Abad ,  Scott E. Andersen ,  Robert E. Buehler ,  Joseph R. Byrum ,  Nordine Cheikh ,  Timothy W. Conner ,  Brian E. Coombs ,  Stanton B. Dotson ,  Patrice Dubois ,  Michael D. Edgerton ,  Dane K. Fisher ,  Kristine J. Hardeman ,  Gregory J. Heck ,  Gregory J. Hinkle ,  Raghunath V. Lalgudi ,  Jingdong Liu ,  Linda L. Lutfiyya ,  Debbie A. Mahadeo ,  James D. Masucci ,  James D. McIninch ,  Philip W. Miller ,  Donald E. Nelson ,  Ming Peng ,  Thomas G. Ruff ,  Hridayabhiranjan Shukla ,  Joshua Stein ,  Michael D. Thompson ,  Kunsheng Wu

发明人： Thomas J. La Rosa ,  David K. Kovalic ,  Yihua Zhou ,  Yongwei Cao ,  Mark S. Abad ,  Scott E. Andersen ,  Robert E. Buehler ,  Joseph R. Byrum ,  Nordine Cheikh ,  Timothy W. Conner ,  Brian E. Coombs ,  Stanton B. Dotson ,  Patrice Dubois ,  Michael D. Edgerton ,  Dane K. Fisher ,  Kristine J. Hardeman ,  Gregory J. Heck ,  Gregory J. Hinkle ,  Raghunath V. Lalgudi ,  Jingdong Liu ,  Linda L. Lutfiyya ,  Debbie A. Mahadeo ,  James D. Masucci ,  James D. McIninch ,  Philip W. Miller ,  Donald E. Nelson ,  Ming Peng ,  Thomas G. Ruff ,  Hridayabhiranjan Shukla ,  Joshua Stein ,  Michael D. Thompson ,  Kunsheng Wu

IPC分类号： C12N15/00 ,  A01H5/00 ,  A01H1/00 ,  C07H21/04 ,  C07K14/415

摘要： Polynucleotides useful for improvement of plants are provided. In particular, polynucleotide sequences are provided from plant sources. Polypeptides encoded by the polynucleotide sequences are also provided. The disclosed polynucleotides and polypeptides find use in production of transgenic plants to produce plants having improved properties.

公开(公告)号：US07807874B2

公开(公告)日：2010-10-05

申请号：US11007819

申请日：2004-12-08

申请人： Santana Dasgupta ,  Targolli L. Jayaprakash ,  Carolyn J. Thai ,  Kottaram Krishnadas Narayanan ,  Thomas G. Ruff ,  Stanton B. Dotson

发明人： Santana Dasgupta ,  Targolli L. Jayaprakash ,  Carolyn J. Thai ,  Kottaram Krishnadas Narayanan ,  Thomas G. Ruff ,  Stanton B. Dotson

IPC分类号： C12N15/82 ,  A01H5/00

CPC分类号： C12N15/8273 ,  C07K14/415 ,  C12N15/8271

摘要： The present invention provides a method and DNA molecules that when expressed in a plant produces transgenic plants with improved abiotic stress tolerance. The invention includes plant expression vectors comprising the DNA molecules, and plants containing such DNA molecules.

公开(公告)号：US20090044297A1

公开(公告)日：2009-02-12

申请号：US11982010

申请日：2007-10-31

申请人： Scott E. Andersen ,  Yongwei Cao ,  Stanton B. Dotson ,  Michael D. Edgerton ,  David K. Kovalic ,  Linda L. Lutfiyya ,  Zhidong Xie ,  Gregory R. Heck ,  Thomas J. La Rosa ,  Jingdong Liu ,  Jingrui Wu ,  Garrett J. Lee ,  Thomas R. Adams ,  Donald E. Nelson ,  Timothy Conner

发明人： Scott E. Andersen ,  Yongwei Cao ,  Stanton B. Dotson ,  Michael D. Edgerton ,  David K. Kovalic ,  Linda L. Lutfiyya ,  Zhidong Xie ,  Gregory R. Heck ,  Thomas J. La Rosa ,  Jingdong Liu ,  Jingrui Wu ,  Garrett J. Lee ,  Thomas R. Adams ,  Donald E. Nelson ,  Timothy Conner

IPC分类号： C12N15/29 ,  A01H5/00

CPC分类号： C12N15/8273

摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits

摘要翻译： 本发明提供具有用于表达蛋白质的重组DNA的转基因植物细胞，其可用于赋予转基因作物植物增强的农艺性状。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐寒性，增加的产量，增强的氮利用效率，增强的氮利用效率， 种子蛋白和增强种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法

公开(公告)号：US07365185B2

公开(公告)日：2008-04-29

申请号：US09815264

申请日：2001-03-23

申请人： Andrey A. Boukharov ,  Yongwei Cao ,  Stanton B. Dotson ,  Jeffrey M. Koshi ,  David K. Kovalic ,  Jingdong Liu ,  James D. McIninch ,  Wei Wu

发明人： Andrey A. Boukharov ,  Yongwei Cao ,  Stanton B. Dotson ,  Jeffrey M. Koshi ,  David K. Kovalic ,  Jingdong Liu ,  James D. McIninch ,  Wei Wu

IPC分类号： C07H21/04 ,  C07H21/02 ,  A01H5/00

CPC分类号： C12N15/8216 ,  C07K14/415 ,  C12N15/8227

摘要： The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same.

摘要翻译： 本发明公开了水稻基因组启动子序列。 促进剂特别适用于水稻和其他谷类作物。 还公开了改性，制备和使用促进剂的方法。 本发明还公开了组合物，转化的宿主细胞，转基因植物和含有水稻基因组启动子序列的种子，以及其制备和使用方法。

公开(公告)号：US07335812B2

公开(公告)日：2008-02-26

申请号：US10513167

申请日：2003-05-14

申请人： Mary Fernandes ,  Zhidong Xie ,  Stanton B. Dotson

发明人： Mary Fernandes ,  Zhidong Xie ,  Stanton B. Dotson

IPC分类号： C12N15/82 ,  A01H5/00

CPC分类号： C07K14/415 ,  C12N15/8261 ,  Y02A40/146

摘要： The present invention provides methods and DNA molecules useful for producing transgenic plants with agronomically desired traits based on altered sizes of plant organs and tissues.

摘要翻译： 本发明提供了用于根据植物器官和组织的大小改变产生具有农学上所需性状的转基因植物的方法和DNA分子。

公开(公告)号：US06953577B2

公开(公告)日：2005-10-11

申请号：US10299867

申请日：2002-11-19

申请人： Carolyn J. Sympson ,  Rajeev Aurora ,  Stanton B. Dotson ,  Ronald B. Frazier ,  Cynthia L. Woods ,  Hamideh Zakeri ,  Xianzhi Zhou

发明人： Carolyn J. Sympson ,  Rajeev Aurora ,  Stanton B. Dotson ,  Ronald B. Frazier ,  Cynthia L. Woods ,  Hamideh Zakeri ,  Xianzhi Zhou

IPC分类号： A61K38/00 ,  A61K39/00 ,  C12N9/48 ,  A01N63/00 ,  C07H21/04 ,  C12N1/20 ,  C12N15/00

CPC分类号： C12Y304/11018 ,  A61K38/00 ,  A61K39/00 ,  C12N9/48

摘要： Methionine aminopeptidases catalyse the co-translational removal of amino terminal methionine residues from nascent polypeptide chains. A newly-discovered enzyme, designated methionine aminopeptidase type-3 (MetAP-3), has a substrate specificity which is similar to MetAP-1 and MetAP-2, although it is not inhibited by fumagillin, an irreversible inhibitor of MetAP-2. MetAP-3 also preferentially localizes to mitochondria, unlike MetAP-1 and MetAP-2, which accumulate in the cytoplasm. One embodiment of the present invention relates to human cDNAs encoding polypeptides comprising MetAP-3. Other embodiments of the invention relate to nucleic acid molecules derived from these cDNAs, including complements, homologues, and fragments thereof, and methods of using these nucleic acid molecules, to generate polypeptides and fragments thereof. Other embodiments of the invention relate to antibodies directed against polypeptides comprising MetAP-3, and methods to screen for compounds or compositions that preferentially or specifically effect the activity of polypeptides comprising MetAP-3.

摘要翻译： 甲硫氨酸氨基肽酶催化从新生多肽链共转移氨基末端甲硫氨酸残基。 称为甲硫氨酸氨基肽酶-3型（MetAP-3）的新发现的酶具有与MetAP-1和MetAP-2相似的底物特异性，尽管它不被万古霉素（Metap-2的不可逆抑制剂）抑制。 MetAP-3也优先定位于线粒体，不同于MetAP-1和MetAP-2，其积聚在细胞质中。 本发明的一个实施方案涉及编码包含MetAP-3的多肽的人cDNA。 本发明的其它实施方案涉及衍生自这些cDNA的核酸分子，包括其互补序列，同系物及其片段，以及使用这些核酸分子的方法来产生其多肽及其片段。 本发明的其它实施方案涉及针对包含MetAP-3的多肽的抗体，以及筛选优先或特异性影响包含MetAP-3的多肽的活性的化合物或组合物的方法。

公开(公告)号：US20120317677A1

公开(公告)日：2012-12-13

申请号：US13444802

申请日：2012-04-11

申请人： Scott E. Andersen ,  Yongwei Cao ,  Stanton B. Dotson ,  Michael D. Edgerton ,  David K. Kovalic ,  Linda L. Lutfiyya ,  Zhidong Xie ,  Gregory R. Heck ,  Thomas J. La Rosa ,  Jingdong Liu ,  Jingrui Wu ,  Garrett J. Lee ,  Thomas R. Adams ,  Donald E. Nelson ,  Timothy Conner

发明人： Scott E. Andersen ,  Yongwei Cao ,  Stanton B. Dotson ,  Michael D. Edgerton ,  David K. Kovalic ,  Linda L. Lutfiyya ,  Zhidong Xie ,  Gregory R. Heck ,  Thomas J. La Rosa ,  Jingdong Liu ,  Jingrui Wu ,  Garrett J. Lee ,  Thomas R. Adams ,  Donald E. Nelson ,  Timothy Conner

IPC分类号： A01H5/00 ,  C12N15/82 ,  A01H1/06 ,  A01H5/10

CPC分类号： C12N15/8271 ,  A01H1/06 ,  C12N15/8273

摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits

摘要翻译： 本发明提供具有用于表达蛋白质的重组DNA的转基因植物细胞，其可用于赋予转基因作物植物增强的农艺性状。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐寒性，增加的产量，增强的氮利用效率，增强的氮利用效率， 种子蛋白和增强种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法

公开(公告)号：US08324482B2

公开(公告)日：2012-12-04

申请号：US12972782

申请日：2010-12-20

申请人： Jindong Sun ,  Kimberly Zobrist ,  Jingrui Wu ,  Changlin Fu ,  Stanton B. Dotson ,  Linda Lutfiyya

发明人： Jindong Sun ,  Kimberly Zobrist ,  Jingrui Wu ,  Changlin Fu ,  Stanton B. Dotson ,  Linda Lutfiyya

IPC分类号： C12N15/82 ,  A01H5/10

CPC分类号： C07K14/415 ,  C07K14/4702 ,  C12N15/8247 ,  C12N15/8261 ,  C12N15/8273 ,  Y02A40/146

摘要： Disclosed herein are transgenic plants having recombinant DNA which expresses a G1073 transcription factor which provides enhanced resistance and/or tolerance to water deficit. More specifically the DNA constructs comprise a polynucleotide which encodes at least a functional part of a G1073 transcription factor or a homologous transcription factor.

摘要翻译： 本文公开了具有表达G1073转录因子的重组DNA的转基因植物，其提供增强的抗性和/或耐水亏性。 更具体地，DNA构建体包含编码G1073转录因子或同源转录因子的至少功能部分的多核苷酸。

公开(公告)号：US20120227131A1

公开(公告)日：2012-09-06

申请号：US13199773

申请日：2011-09-08

申请人： Mark S. Abad ,  Thomas R. Adams ,  Ameeta K. Argarwal ,  James A. Ball ,  Paolo Castiglioni ,  Banu Gopalan ,  Erin Bell ,  Shobha Char ,  Robert J. Bensen ,  Raghava S. Boddupalli ,  Alessandra Frizzi ,  Jill Deikman ,  Robert D'Ordine ,  Michael D. Edgerton ,  Xianfeng Chen ,  Mary Fernandes ,  Paul S. Chomet ,  Stephen Duff ,  Deborah G. Rucker ,  Changlin Fu ,  Jeffrey E. Ahrens ,  Stanton B. Dotson ,  Richard E. Finger ,  Jinzhuo Dong ,  Molian Deng

发明人： Mark S. Abad ,  Thomas R. Adams ,  Ameeta K. Argarwal ,  James A. Ball ,  Paolo Castiglioni ,  Banu Gopalan ,  Erin Bell ,  Shobha Char ,  Robert J. Bensen ,  Raghava S. Boddupalli ,  Alessandra Frizzi ,  Jill Deikman ,  Robert D'Ordine ,  Michael D. Edgerton ,  Xianfeng Chen ,  Mary Fernandes ,  Paul S. Chomet ,  Stephen Duff ,  Deborah G. Rucker ,  Changlin Fu ,  Jeffrey E. Ahrens ,  Stanton B. Dotson ,  Richard E. Finger ,  Jinzhuo Dong ,  Molian Deng

IPC分类号： A01H5/00 ,  A01H1/02 ,  C12Q1/68 ,  C12N5/10 ,  A01H5/10

CPC分类号： C12N15/8209 ,  A01H5/10 ,  C07K14/4702 ,  C12N15/8247 ,  C12N15/8251 ,  C12N15/8261 ,  C12N15/8273 ,  C12N15/8274

摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.

摘要翻译： 本发明提供具有用于表达蛋白质的重组DNA的转基因植物细胞，其可用于赋予转基因作物植物增强的农艺性状。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐寒性，增加的产量，增强的氮利用效率，增强的氮利用效率， 种子蛋白和增强种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法。

公开(公告)号：US20110099655A1

公开(公告)日：2011-04-28

申请号：US12972782

申请日：2010-12-20

申请人： Jindong Sun ,  Kimberly Zobrist ,  Jingrui Wu ,  Changlin Fu ,  Stanton B. Dotson ,  Linda Lutfiyya

发明人： Jindong Sun ,  Kimberly Zobrist ,  Jingrui Wu ,  Changlin Fu ,  Stanton B. Dotson ,  Linda Lutfiyya

IPC分类号： A01H5/00 ,  A01H5/10 ,  C12N15/82 ,  A01H1/02

CPC分类号： C07K14/415 ,  C07K14/4702 ,  C12N15/8247 ,  C12N15/8261 ,  C12N15/8273 ,  Y02A40/146

摘要： Disclosed herein are transgenic plants having recombinant DNA which expresses a G1073 transcription factor which provides enhanced resistance and/or tolerance to water deficit. More specifically the DNA constructs comprise a polynucleotide which encodes at least a functional part of a G1073 transcription factor or a homologous transcription factor.

摘要翻译： 本文公开了具有表达G1073转录因子的重组DNA的转基因植物，其提供增强的抗性和/或耐水亏性。 更具体地，DNA构建体包含编码G1073转录因子或同源转录因子的至少功能部分的多核苷酸。