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1.发明授权公开(公告)号：US08211682B2
公开(公告)日：2012-07-03
申请号：US12244940
申请日：2008-10-03
申请人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
IPC分类号： C12N9/00 , C12N11/02 , C12N11/08 , C12N9/04 , C12N9/14 , C12N9/76 , G01N33/544 , G01N33/545 , C07K1/14 , C07K1/22 , C07K17/02 , C07K17/08
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
摘要翻译： 本发明涉及一种复合材料，其包括具有延伸穿过支撑构件的多个孔的支撑构件，并且位于支撑构件的孔中并填充支撑构件的孔，大孔交联凝胶。 本发明还涉及一种制备上述复合材料及其用途的方法。 复合材料例如用于分离物质，例如通过过滤或吸附，包括色谱法，用作合成中的载体或用作细胞生长的载体。
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公开(公告)号：US08383782B2
公开(公告)日：2013-02-26
申请号：US12609689
申请日：2009-10-30
申请人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
IPC分类号： C07K1/14 , C07K1/22 , C07K17/02 , C07K17/08 , C12N9/00 , C12N11/02 , C12N11/08 , C12N9/14 , C12N9/76 , G01N33/544 , G01N33/545
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
摘要翻译： 本发明涉及一种复合材料，其包括具有延伸穿过支撑构件的多个孔的支撑构件，并且位于支撑构件的孔中并填充支撑构件的孔，大孔交联凝胶。 本发明还涉及一种制备上述复合材料及其用途的方法。 复合材料例如用于分离物质，例如通过过滤或吸附，包括色谱法，用作合成中的载体或用作细胞生长的载体。
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3.发明授权Composite materials comprising supported porous gels containing reactive functional groups 有权复合材料包含含有反应性官能团的支撑多孔凝胶公开(公告)号：US08206982B2
公开(公告)日：2012-06-26
申请号：US12250869
申请日：2008-10-14
申请人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
摘要翻译： 本发明涉及一种复合材料，其包括具有延伸穿过支撑构件的多个孔的支撑构件，并且位于支撑构件的孔中并填充支撑构件的孔，大孔交联凝胶。 本发明还涉及一种制备上述复合材料及其用途的方法。 复合材料例如用于分离物质，例如通过过滤或吸附，包括色谱法，用作合成中的载体或用作细胞生长的载体。
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公开(公告)号：US20090176052A1
公开(公告)日：2009-07-09
申请号：US11573540
申请日：2005-08-12
CPC分类号： B01D69/10 , B01D67/0009 , B01D67/0088 , B01D69/02 , B01D69/08 , B01D71/08 , B01D71/28 , B01D71/38 , B01D71/40 , B01D71/52 , B01D71/68 , B01D71/82 , B01D2323/283 , B01J20/28097 , B01J20/327 , B01J20/3272 , B01J20/3276 , Y10T428/24025 , Y10T428/24322
摘要： Disclosed is a composite material comprising a support member that has a plurality of pores extending therethrough, which pores are durably filled or coated with a non crosslinked gel polymer. Also disclosed is a process for the preparation of the composite material, use of the composite material as a separation medium, and a filtering apparatus comprising the composite material.
摘要翻译： 公开了一种复合材料，其包括具有延伸穿过其中的多个孔的支撑构件，该孔保持性地填充或涂覆有非交联凝胶聚合物。 还公开了复合材料的制备方法，复合材料作为分离介质的使用，以及包含复合材料的过滤装置。
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公开(公告)号：US20090035552A1
公开(公告)日：2009-02-05
申请号：US12250869
申请日：2008-10-14
申请人： Ronald F. Childs , Carlos Felipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Felipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
IPC分类号： B32B3/26
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
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公开(公告)号：US20100044316A1
公开(公告)日：2010-02-25
申请号：US12609689
申请日：2009-10-30
申请人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
摘要翻译： 本发明涉及一种复合材料，其包括具有延伸穿过支撑构件的多个孔的支撑构件，并且位于支撑构件的孔中并填充支撑构件的孔，大孔交联凝胶。 本发明还涉及一种制备上述复合材料及其用途的方法。 复合材料例如用于分离物质，例如通过过滤或吸附，包括色谱法，用作合成中的载体或用作细胞生长的载体。
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公开(公告)号：US20090029438A1
公开(公告)日：2009-01-29
申请号：US12244940
申请日：2008-10-03
申请人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
IPC分类号： C12N9/02 , B01D15/26 , C12N7/02 , C12N5/00 , C07K1/14 , C07K14/52 , C12N9/00 , C07K16/00 , C07K14/805 , C07H21/04 , C07H21/02 , C07H21/00 , C07K14/765 , C07K14/77 , C12N9/14
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
摘要翻译： 本发明涉及一种复合材料，其包括具有延伸穿过支撑构件的多个孔的支撑构件，并且位于支撑构件的孔中并填充支撑构件的孔，大孔交联凝胶。 本发明还涉及一种制备上述复合材料及其用途的方法。 复合材料例如用于分离物质，例如通过过滤或吸附，包括色谱法，用作合成中的载体或用作细胞生长的载体。
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公开(公告)号：US20080314831A1
公开(公告)日：2008-12-25
申请号：US11950562
申请日：2007-12-05
申请人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
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公开(公告)号：US08652849B2
公开(公告)日：2014-02-18
申请号：US12250861
申请日：2008-10-14
申请人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
IPC分类号： G01N33/20 , G01N33/544 , G01N33/545 , C12N9/00 , C12N11/02 , C12N11/08 , C07K1/14 , C07K1/22 , C07K17/02 , C07K17/08
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
摘要翻译： 本发明涉及一种复合材料，其包括具有延伸穿过支撑构件的多个孔的支撑构件，并且位于支撑构件的孔中并填充支撑构件的孔，大孔交联凝胶。 本发明还涉及一种制备上述复合材料及其用途的方法。 复合材料例如用于分离物质，例如通过过滤或吸附，包括色谱法，用作合成中的载体或用作细胞生长的载体。
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10.发明授权Separating substances with supported porous gels containing metal-affinity ligands complexed with metal ions 有权分离物质与负载的多孔凝胶含有与金属离子络合的金属亲和配体公开(公告)号：US08192971B2
公开(公告)日：2012-06-05
申请号：US12211618
申请日：2008-09-16
申请人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
发明人： Ronald F. Childs , Carlos Filipe , Raja Ghosh , Alicja M. Mika , Jinsheng Zhou , Elena N. Komkova , Marcus Y. Kim , Tapan K. Dey
IPC分类号： C12N9/00 , C12N11/02 , C12N11/08 , C12N9/14 , C12N9/76 , G01N33/544 , G01N33/545 , C07K1/14 , C07K1/22 , C07K17/02 , C07K17/08
CPC分类号： C07K1/04 , B01D15/327 , B01D15/34 , B01D15/36 , B01D15/361 , B01D15/3804 , B01D67/0006 , B01D69/02 , B01D69/10 , B01D69/141 , B01D71/40 , B01D2323/30 , B01D2323/34 , B01D2325/12 , B01D2325/14 , B01D2325/16 , B01D2325/38 , B01J20/261 , B01J20/262 , B01J20/264 , B01J20/265 , B01J20/267 , B01J20/28004 , B01J20/28011 , B01J20/28023 , B01J20/28033 , B01J20/28047 , B01J20/28069 , B01J20/28078 , B01J20/28085 , B01J20/28097 , B01J20/285 , B01J20/286 , B01J20/291 , B01J20/3064 , B01J20/321 , B01J20/3212 , B01J20/3272 , B01J20/3276 , B01J20/3278 , B01J20/3282 , B01J39/26 , B01J41/20 , B01J47/018 , B01J47/12 , C07K1/20 , C07K1/22 , C07K1/34 , Y10S530/812 , Y10S530/815 , Y10T428/249978 , Y10T428/249994
摘要： This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth.
摘要翻译： 本发明涉及一种复合材料，其包括具有延伸穿过支撑构件的多个孔的支撑构件，并且位于支撑构件的孔中并填充支撑构件的孔，大孔交联凝胶。 本发明还涉及一种制备上述复合材料及其用途的方法。 复合材料例如用于分离物质，例如通过过滤或吸附，包括色谱法，用作合成中的载体或用作细胞生长的载体。
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