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公开(公告)号：US2739819A
公开(公告)日：1956-03-27
申请号：US38481153
申请日：1953-10-08
发明人： ARTHUR STONER CLAIR
IPC分类号： A63C17/02
CPC分类号： A63C17/02
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公开(公告)号：US09730912B2
公开(公告)日：2017-08-15
申请号：US12445163
申请日：2007-10-12
申请人： Neil Thomas Thompson
发明人： Neil Thomas Thompson
IPC分类号： A61K31/4035 , A61K31/437 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K45/06
CPC分类号： A61K31/4035 , A61K31/437 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K45/06 , Y02A50/411 , A61K2300/00
摘要： The invention provides the use of a compound for the manufacture of a medicament for the treatment of pain, wherein the compound is a compound of the formula (VI): or a salt, solvate, tautomer or N-oxide thereof; wherein the bicyclic group: is selected from the structures C1, C5 and C6: wherein n, R1, R2a, R3, R4a, R8 and R10 are as defined in the claims. The invention also provides the use of a compound of the formula (VI) for the manufacture of a medicament for the prophylaxis or treatment of a fungal, protozoal, viral or parasitic disease state or condition (other than a disease state or condition due to Plasmodium falciparum) or for use in the prophylaxis or treatment of Ewing's sarcoma, atherosclerosis or lupus erythematosus.
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公开(公告)号：US08398747B2
公开(公告)日：2013-03-19
申请号：US12489759
申请日：2009-06-23
IPC分类号： B01D53/02
CPC分类号： B01J20/28052 , B01D15/00 , B01D53/04 , B01D53/0462 , B01D53/047 , B01D2253/102 , B01D2253/104 , B01D2253/106 , B01D2253/108 , B01D2256/24 , B01D2257/504 , B01D2257/704 , B01D2257/80 , B01D2259/402 , B01D2259/4145 , B01J20/046 , B01J20/08 , B01J20/10 , B01J20/186 , B01J20/20 , B01J20/3416 , B01J20/3458 , B01J20/3483 , B01J2220/42 , B01J2220/56 , C07C7/12 , C07C7/13 , Y02C10/08 , Y02P20/152 , C07C11/24
摘要： This invention relates in part to a process for producing high purity acetylene by withdrawing a crude acetylene stream from a storage source, and passing said stream through an adsorbent bed that contains layered adsorption media to selectively remove moisture, solvent and carbon dioxide from the stream, thereby producing the high purity acetylene. The adsorption media is regenerated in-situ. The high purity acetylene product is useful as a source material for depositing carbon and carbon-containing films in semiconductor applications.
摘要翻译： 本发明部分地涉及通过从储存源中取出粗乙炔流并使所述物流通过含有层状吸附介质的吸附剂床来选择性地从流中去除水分，溶剂和二氧化碳来生产高纯度乙炔的方法， 从而产生高纯度乙炔。 吸附介质原位再生。 高纯度乙炔产物可用作在半导体应用中沉积碳和含碳膜的原料。
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公开(公告)号：US20130040066A1
公开(公告)日：2013-02-14
申请号：US13642754
申请日：2011-04-27
IPC分类号： B05D1/06
CPC分类号： B05D1/06 , B05B5/032 , B05B5/043 , B05B5/0535 , B05B5/0536 , B05D1/36 , B05D7/542 , B05D2451/00 , B05D2401/32
摘要： A method for the application of at least two different powder coating layers to a substrate comprising the steps of application of a first powder coating layer followed by the application of a second powder coating layer, without any substantial curing of the first powder coating layer prior to the application of the second powder coating layer, followed by the simultaneous curing of the first powder coating layer and the second powder coating layer, wherein the first powder coating layer is applied to the substrate using a corona charging system and the second powder coating layer is applied to the substrate using a tribo charging system, or the first powder coating layer is applied to the substrate using a tribo charging system and the second powder coating layer is applied to the substrate using a corona charging system and the first powder coating layer and second powder coating layer have an opposite electrostatic polarity.
摘要翻译： 一种用于将至少两种不同的粉末涂层施加到基底上的方法，包括以下步骤：施加第一粉末涂层，然后施加第二粉末涂层，而不在第一粉末涂层之前基本上固化第一粉末涂层 施加第二粉末涂层，然后同时固化第一粉末涂层和第二粉末涂层，其中使用电晕充电系统将第一粉末涂层施加到基底上，第二粉末涂层为 使用摩擦带电系统施加到基板上，或者使用摩擦带电系统将第一粉末涂层施加到基板上，并且使用电晕充电系统将第二粉末涂层施加到基板上，并且将第二粉末涂层施加到基板 粉末涂层具有相反的静电极性。
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公开(公告)号：US07842630B2
公开(公告)日：2010-11-30
申请号：US11985118
申请日：2007-11-14
CPC分类号： C08K5/42 , A61L15/18 , B29C47/0011 , B29C47/0014 , B29C47/822 , B29C47/8895 , D01F1/10 , D01F6/62 , Y10T428/249936 , Y10T428/249938 , Y10T442/60 , Y10T442/607 , Y10T442/637
摘要： The present invention is aimed at a method of providing wettability to polyester fibers or filaments, to woven or nonwoven fabrics made therefrom and to resultant articles of manufacture. The method comprises melt extruding a mixture comprising a polyester and one or more alkyl metal sulfonates where the metal is Na, Li or K and the alkyl is straight or branched chain alkyl of 12 to 15 carbon atoms, or is straight or branched chain alkenyl of 12 to 18 carbon atoms. The alkyl metal sulfonates are present from about 2% to about 5% by weight based on the weight of the polyester. A post treatment step such as an alkaline treatment step is not included. The melt extrusion mixtures do not include certain additives such as polyoxyalkylene compounds, alkylmonoethonolamide compounds, alkyldiethanolamine compounds and polyetheramide compounds.
摘要翻译： 本发明的目的在于提供对聚酯纤维或长丝的润湿性，由其制成的织造或非织造织物以及所得制品。 该方法包括将包含聚酯和一种或多种烷基金属磺酸盐的混合物熔融挤出，其中金属是Na，Li或K，并且烷基是12至15个碳原子的直链或支链烷基，或是直链或支链链烯基 12至18个碳原子。 基于聚酯的重量，烷基金属磺酸盐的存在量为约2重量％至约5重量％。 不包括碱处理步骤等后处理步骤。 熔融挤出混合物不包括某些添加剂，例如聚氧化烯化合物，烷基一乙醇胺化合物，烷基二乙醇胺化合物和聚醚酰胺化合物。
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6.发明申请PHARMACEUTICAL COMBINATIONS COMPRISING PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS 失效包含作为蛋白激酶调节剂的吡唑衍生物的药物组合公开(公告)号：US20100166699A1
公开(公告)日：2010-07-01
申请号：US11993823
申请日：2006-06-21
申请人： Neil Thomas Thompson , Robert George Boyle , Ian Collins , Michelle Dawn Garrett , John Francis Lyons , Kyla Merriom Thompson
发明人： Neil Thomas Thompson , Robert George Boyle , Ian Collins , Michelle Dawn Garrett , John Francis Lyons , Kyla Merriom Thompson
IPC分类号： A61K38/20 , A61K31/497 , A61K39/395 , A61K31/517 , A61K31/5377 , A61K31/4439 , A61K31/565 , A61K31/566 , A61K38/21 , A61K33/24 , A61K31/4375 , A61K31/675 , A61K31/551 , A61P35/00
CPC分类号： A61K45/06 , A61K31/415 , A61K31/454 , A61K2300/00
摘要： The invention provides a combination comprising an ancillary compound (e.g. one, two or more ancillary compounds) and a compound of the formula (I) having protein kinase B inhibiting activity: wherein A is a saturated hydrocarbon linker group containing from 1 to 7 carbon atoms, the linker group having a maximum chain length of 5 atoms extending between R1 and NR2R3 and a maximum chain length of 4 atoms extending between E and NR2R3, wherein one of the carbon atoms in the linker group may optionally be replaced by an oxygen or nitrogen atom; and wherein the carbon atoms of the linker group A may optionally bear one or more substituents selected from oxo, fluorine and hydroxy, provided that the hydroxy group when present is not located at a carbon atom a with respect to the NR2R3 group and provided that the oxo group when present is located at a carbon atom a with respect to the NR2R3 group; E is a monocyclic or bicyclic carbocyclic or heterocyclic group; R is an aryl or heteroaryl group; and R2, R3, R4 and R5 are as defined in the claims. Also provided are patient packs, pharmaceutical kits and packs and compositions containing the combinations, methods for preparing the combinations and their use in combination therapy as anticancer agents.
摘要翻译： 本发明提供包含辅助化合物（例如一种，两种或多种辅助化合物）和具有蛋白激酶B抑制活性的式（I）化合物的组合的组合：其中A是含有1至7个碳原子的饱和烃连接基团 ，连接基团具有在R1和NR2R3之间延伸的5个原子的最大链长度，以及在E和NR 2 R 3之间延伸的4个原子的最大链长度，其中连接基团中的一个碳原子可以任选被氧或氮取代 原子; 并且其中连接基团A的碳原子可以任选地具有一个或多个选自氧代，氟和羟基的取代基，条件是当存在的羟基不相对于NR 2 R 3基团位于碳原子a时， 存在时的氧代基相对于NR 2 R 3基团位于碳原子a; E是单环或双环碳环或杂环基; R是芳基或杂芳基; 并且R 2，R 3，R 4和R 5如权利要求中所定义。 还提供了包含组合的患者包装，药物盒和包装和组合，用于制备组合的方法及其在联合治疗中作为抗癌剂的用途。
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公开(公告)号：US20080107548A1
公开(公告)日：2008-05-08
申请号：US11591824
申请日：2006-11-02
CPC分类号： F15B3/00 , B23B31/302 , B23B2231/12
摘要： This invention relates generally to a pneumatic and hydraulic rotating, reciprocating cylinder apparatus to be mounted on the proximal end of CNC lathe spindles, vertical or inverted machining centers, hydraulic machining work cells or rotary transfer machines to actuate work holding chucks, work holding fixtures, clamping apparatus or work supports on the distal end of said spindles. More specifically, this invention relates to an actuating system with the capability of boosting the input hydraulic pressure to the holding device by a pre-set multiple up to 5000 psi.
摘要翻译： 本发明一般涉及一种气动和液压旋转的往复式气缸装置，其安装在CNC车床主轴的近端，垂直或倒立的加工中心，液压加工工作单元或旋转传送机器，用于致动工作夹紧卡盘，工件夹持装置， 夹紧装置或工件支撑件在所述主轴的远端上。 更具体地，本发明涉及一种致动系统，该致动系统具有通过高达5000psi的预设倍数将保持装置的输入液压升高的能力。
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公开(公告)号：US20080064285A1
公开(公告)日：2008-03-13
申请号：US11985118
申请日：2007-11-14
申请人： Colin Morton , Thomas Thompson , Ashutosh Sharma
发明人： Colin Morton , Thomas Thompson , Ashutosh Sharma
CPC分类号： C08K5/42 , A61L15/18 , B29C47/0011 , B29C47/0014 , B29C47/822 , B29C47/8895 , D01F1/10 , D01F6/62 , Y10T428/249936 , Y10T428/249938 , Y10T442/60 , Y10T442/607 , Y10T442/637
摘要： The present invention is aimed at a method of providing wettability to polyester fibers or filaments, to woven or nonwoven fabrics made therefrom and to resultant articles of manufacture. The method comprises melt extruding a mixture comprising a polyester and one or more alkyl metal sulfonates where the metal is Na, Li or K and the alkyl is straight or branched chain alkyl of 12 to 15 carbon atoms, or is straight or branched chain alkenyl of 12 to 18 carbon atoms. The alkyl metal sulfonates are present from about 2% to about 5% by weight based on the weight of the polyester. A post treatment step such as an alkaline treatment step is not included. The melt extrusion mixtures do not include certain additives such as polyoxyalkylene compounds, alkylmonoethonolamide compounds, alkyldiethanolamine compounds and polyetheramide compounds.
摘要翻译： 本发明的目的在于提供对聚酯纤维或长丝的润湿性，由其制成的织造或非织造织物以及所得制品。 该方法包括熔融挤出包含聚酯和一种或多种烷基金属磺酸盐的混合物，其中金属是Na，Li或K，并且烷基是12至15个碳原子的直链或支链烷基，或者是直链或支链链烯基 12至18个碳原子。 基于聚酯的重量，烷基金属磺酸盐的存在量为约2重量％至约5重量％。 不包括碱处理步骤等后处理步骤。 熔融挤出混合物不包括某些添加剂，例如聚氧化烯化合物，烷基一乙醇胺化合物，烷基二乙醇胺化合物和聚醚酰胺化合物。
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公开(公告)号：US20060188617A1
公开(公告)日：2006-08-24
申请号：US11407613
申请日：2006-04-20
IPC分类号： A23L3/32
摘要： A pourer for improving the taste of water includes a base and a tubular member extending longitudinally through the base. A spout extends outwardly from the tubular member and at least two magnets disposed longitudinally along the tubular member are provided for exposing the water to a magnetic field as the water passes through the tubular member and spout.
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公开(公告)号：US07080592B2
公开(公告)日：2006-07-25
申请号：US11030447
申请日：2005-01-06
IPC分类号： F15B11/08
CPC分类号： F16C33/30
摘要： In accordance with the present invention a pneumatic or hydraulic rotating cylinder capable of very high speeds is embodied. It is constructed of light weight materials, minimizing the mass but is given the ability to run at high speed in spite of vibrating environments, supply line condensation, contaminants and various attitudinal mounting by the anti-seizure insert bearing inserted into the distributor and sleeving the rotating shaft.
摘要翻译： 根据本发明，具有能够非常高速度的气动或液压旋转气缸。 它由重量轻的材料构成，尽量减少质量，但是尽管振动环境，供应线冷凝，污染物以及插入到分配器中的防卡塞插入轴承的各种姿态安装，但能够高速运行。 旋转轴。
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