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1.发明授权公开(公告)号：US08911098B2
公开(公告)日：2014-12-16
申请号：US12583400
申请日：2009-08-20
CPC分类号： G02B7/182 , G02B5/10 , G02B7/183 , Y10T428/24165 , Y10T428/24289 , Y10T428/24306 , Y10T428/2495
摘要： In a substrate, particularly in a substrate for a mirror support, in which recesses are introduced in one surface, preferably in the back side of the substrate, as a result of which, in particular, bridging pieces are defined between the recesses, in order to achieve the situation that despite a reduced weight, a high rigidity still remains, which means only a slight sagging after its correct uptake in a holding device provided for it, it is provided that at least one first portion of the bridging pieces has a width that is different than a second portion of the bridging pieces.
摘要翻译： 在基板中，特别是在用于反射镜支撑的基板中，其中凹部被引入到一个表面中，优选地在基板的背面中被引入，结果，特别地，桥接件被定义在凹部之间，按顺序 为了实现尽管重量减轻的情况，仍然保留高刚性，这意味着在为其设置的保持装置中正确吸收之后只有轻微的下垂，条件是桥接件的至少一个第一部分具有宽度 这不同于桥接件的第二部分。
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2.发明申请LAMINATED, TRANSPARENT SET OF PANES, PROCESS FOR PRODUCING AND BENDING SAME, AND USE THEREOF 审中-公开层叠，透明套，其生产和弯曲的方法及其使用公开(公告)号：US20120028015A1
公开(公告)日：2012-02-02
申请号：US13186845
申请日：2011-07-20
申请人： Andreas Langsdorf , Markus Heiss , Doris Moseler , Axel Ohlinger , Volker Seibert , Otmar Becker , Bernd Ruedinger , Thilo Zachau
发明人： Andreas Langsdorf , Markus Heiss , Doris Moseler , Axel Ohlinger , Volker Seibert , Otmar Becker , Bernd Ruedinger , Thilo Zachau
IPC分类号： B32B7/02 , C03B23/023 , B32B3/00 , B32B17/06 , B32B9/00
CPC分类号： F41H5/0407 , B32B17/10045 , B32B17/10119 , B32B17/10889 , B32B17/10908 , B32B2250/05 , B32B2307/558 , B32B2605/00 , Y10T428/2495 , Y10T428/24967
摘要： Laminated, transparent set of panes made of brittle materials and interleaved laminated films, wherein the brittle materials are various glasses, special glasses, glass-ceramics, transparent ceramics and crystalline materials, process for producing and bending the set of panes and films, and its use thereof, as a bulletproof, unbreakable and shockproof glazing with a low weight per unit area.
摘要翻译： 层叠的，透明的由脆性材料制成的玻璃板和交错层压膜，其中脆性材料是各种玻璃，特殊玻璃，玻璃陶瓷，透明陶瓷和结晶材料，用于生产和弯曲该组玻璃和薄膜的方法及其 作为防弹，防破坏和防震玻璃，具有每单位面积重量轻。
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3.发明申请Method and Device for Separating Plates from Mechanically Brittle and Nonmetal Materials 有权从机械脆性和非金属材料中分离板的方法和装置公开(公告)号：US20090001118A1
公开(公告)日：2009-01-01
申请号：US11658067
申请日：2005-06-15
CPC分类号： C03B33/09 , C03B33/04 , Y10T225/12 , Y10T225/325
摘要： The invention concerns a method for separating plate-shaped workpieces of mechanically brittle and nonmetal materials along any contour desired, comprising the following steps: Scratching of separating lines along the contour up to a depth T by means of a cutting device in at least one side of the plate-shaped workpiece is hereby characterized in that the plate-shaped workpiece is stimulated to bending vibrations at a vibration amplitude along the separating lines, so that the plate-shaped workpiece is completely separated along the separating line.
摘要翻译： 本发明涉及一种用于沿着期望的任何轮廓分离机械脆性和非金属材料的板状工件的方法，包括以下步骤：通过至少一个侧面上的切割装置沿着轮廓划分直到深度T的分离线 其特征在于，板状工件被刺激以沿分离线的振动振幅弯曲振动，使得板状工件沿着分离线完全分离。
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4.发明申请公开(公告)号：US20100103546A1
公开(公告)日：2010-04-29
申请号：US12583400
申请日：2009-08-20
CPC分类号： G02B7/182 , G02B5/10 , G02B7/183 , Y10T428/24165 , Y10T428/24289 , Y10T428/24306 , Y10T428/2495
摘要： In a substrate, particularly in a substrate for a mirror support, in which recesses are introduced in one surface, preferably in the back side of the substrate, as a result of which, in particular, bridging pieces are defined between the recesses, in order to achieve the situation that despite a reduced weight, a high rigidity still remains, which means only a slight sagging after its correct uptake in a holding device provided for it, it is provided that at least one first portion of the bridging pieces has a width that is different than a second portion of the bridging pieces.
摘要翻译： 在基板中，特别是在用于反射镜支撑的基板中，其中凹部被引入到一个表面中，优选地在基板的背面中被引入，结果，特别地，桥接件被定义在凹部之间，按顺序 为了实现尽管重量减轻的情况，仍然保留高刚性，这意味着在为其设置的保持装置中正确吸收之后只有轻微的下垂，条件是桥接件的至少一个第一部分具有宽度 这不同于桥接件的第二部分。
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公开(公告)号：US08864324B2
公开(公告)日：2014-10-21
申请号：US13353648
申请日：2012-01-19
CPC分类号： G02B7/183
摘要： A monolithic substrate of glass or glass ceramics and methods for manufacturing are provided, where the substrate has a lightweight structure. The lightweight structure includes recesses that are delimited by webs, such webs forming tetragonal or four-corner-shaped pockets. Due to the lightweight structure, the weight of the substrate can be significantly reduced, and at the same time a high rigidity can be ensured. The substrate can be used as a mirror support or a mirror and can be employed terrestrially and/or extra-terrestrially.
摘要翻译： 提供玻璃或玻璃陶瓷的整体式基板及其制造方法，其中基板具有轻质结构。 轻质结构包括由腹板限定的凹部，这些腹板形成四角形或四角形的口袋。 由于轻质结构，可以显着地降低基板的重量，同时可以确保高刚性。 衬底可以用作镜子支撑或镜子，并且可以用于地面和/或地面外。
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6.发明授权Method and device for separating plates from mechanically brittle and nonmetal materials 有权从机械脆性和非金属材料中分离板的方法和装置公开(公告)号：US08763872B2
公开(公告)日：2014-07-01
申请号：US11658067
申请日：2005-06-15
IPC分类号： B26F3/00
CPC分类号： C03B33/09 , C03B33/04 , Y10T225/12 , Y10T225/325
摘要： The invention concerns a method for separating plate-shaped workpieces of mechanically brittle and nonmetal materials along any contour desired, comprising the following steps: Scratching of separating lines along the contour up to a depth T by means of a cutting device in at least one side of the plate-shaped workpiece is hereby characterized in that the plate-shaped workpiece is stimulated to bending vibrations at a vibration amplitude along the separating lines, so that the plate-shaped workpiece is completely separated along the separating line.
摘要翻译： 本发明涉及一种用于沿着期望的任何轮廓分离机械脆性和非金属材料的板状工件的方法，包括以下步骤：通过至少一个侧面上的切割装置沿着轮廓划分直到深度T的分离线 其特征在于，板状工件被刺激以沿分离线的振动振幅弯曲振动，使得板状工件沿着分离线完全分离。
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公开(公告)号：US20100182711A1
公开(公告)日：2010-07-22
申请号：US12657314
申请日：2010-01-19
CPC分类号： G02B5/0808 , G02B1/00 , Y10T156/1052 , Y10T428/21 , Y10T428/24149 , Y10T428/24331 , Y10T428/24612
摘要： A substrate and methods of making is provided. The substrate is made of glass or glass ceramic and finds use as a mirror support having a light-weight structure. The substrate includes recesses and is reinforced with covers in the region of bearing points for rigidification.
摘要翻译： 提供了一种底物和制备方法。 基板由玻璃或玻璃陶瓷制成，可用作具有轻质结构的反射镜支架。 衬底包括凹槽，并且在用于刚化的支承点的区域中用盖加强。
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8.发明申请Differentially expressed tumour-specific polypeptides for use in the diagnosis and treatment of cancer 审中-公开用于诊断和治疗癌症的差异表达的肿瘤特异性多肽公开(公告)号：US20090252721A1
公开(公告)日：2009-10-08
申请号：US10571167
申请日：2004-09-20
申请人： Thomas Buschmann , Nikoleta-Kyriaki Fotiadis , Miriam Fuchs , Steffen Heim , Tatiana Lehnherr-Ilina , Stephanie Lamer , Jörn Meuer , Kirsten Rothmann-Cosic , Volker Seibert , Silvia Tortola Perez , Katrin Stedronsky
发明人： Thomas Buschmann , Nikoleta-Kyriaki Fotiadis , Miriam Fuchs , Steffen Heim , Tatiana Lehnherr-Ilina , Stephanie Lamer , Jörn Meuer , Kirsten Rothmann-Cosic , Volker Seibert , Silvia Tortola Perez , Katrin Stedronsky
IPC分类号： A61K39/395 , G01N33/566 , C40B30/04 , A61K31/7105 , A61K45/00 , C07K16/00 , C12Q1/68 , A61P35/00
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178 , G01N33/57407 , G01N33/6893 , G01N2500/00
摘要： The invention relates to agents and methods for the diagnosis, prognosis and treatment of cancer. Specifically, the invention relates to the use of nucleic and amino acid sequences encoding transmembrane superfamily member 6 (TM4SF6), synaptophysin like protein (SYPL), stomatin like 2 (STOML2), Ras related GTP binding protein RAGA), nucleotide sensitive chloride channel 1A (CLNS1A), prion protein (p27-30) (PRNP), guanine nucleotide binding protein beta 2-like 1 (GNB2L1), guanine nucleotide binding protein 4 (GNG4), integral membrane protein 2B (ITM2B), integral membrane protein 1 (ITM1), transmembrane 9 superfamily member 2 (TM9SF2), opiate receptor-like 1 protein (OPRL1), low density lipoprotein receptor-related protein 4 (LRP4), human glomerular epithelial protein 1 (GLEPP1), toll-like receptor 3 (TLR3), and/or zona pellucida glycoprotein 3A (ZP3) for the diagnosis of both early and late stage non-steroid specific cancers, cancer prognosis, as well as screening for therapeutic agents that regulate the gene expression and/or biological activity of said proteins. This invention further relates to the biological technologies designed to inhibit the gene expression and/or biological activity of said proteins including using agents identified in screening assays described herein, vector delivery of antisense polynucleotide sequences, and antibody targeting of said proteins. In specific embodiments, the proteins are of human origin.
摘要翻译： 本发明涉及用于诊断，预后和治疗癌症的药剂和方法。 具体而言，本发明涉及编码跨膜超家族成员6（TM4SF6），突触素样蛋白（SYPL），类似2的孔蛋白（STOML2），Ras相关GTP结合蛋白RAGA的核酸和氨基酸序列，核苷酸敏感性氯通道1A （CLNS1A），朊病毒蛋白（p27-30）（PRNP），鸟嘌呤核苷酸结合蛋白β2-样1（GNB2L1），鸟嘌呤核苷酸结合蛋白4（GNG4），整合膜蛋白2B（ITM2B），整合膜蛋白1 ITM1），跨膜9超家族成员2（TM9SF2），阿片受体样1蛋白（OPRL1），低密度脂蛋白受体相关蛋白4（LRP4），人肾小球上皮蛋白1（GLEPP1），toll样受体3（TLR3 ）和/或透明带糖蛋白3A（ZP3），用于诊断早期和晚期非类固醇特异性癌症，癌症预后，以及筛选调节所述蛋白质的基因表达和/或生物活性的治疗剂 。 本发明还涉及设计用于抑制所述蛋白质的基因表达和/或生物活性的生物学技术，包括使用本文所述的筛选测定中鉴定的试剂，反义多核苷酸序列的载体递送和所述蛋白质的抗体靶向。 在具体实施方案中，蛋白质是人源的。
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公开(公告)号：US20120182636A1
公开(公告)日：2012-07-19
申请号：US13353648
申请日：2012-01-19
CPC分类号： G02B7/183
摘要： A monolithic substrate of glass or glass ceramics and methods for manufacturing are provided, where the substrate has a lightweight structure. The lightweight structure includes recesses that are delimited by webs, such webs forming tetragonal or four-corner-shaped pockets. Due to the lightweight structure, the weight of the substrate can be significantly reduced, and at the same time a high rigidity can be ensured. The substrate can be used as a mirror support or a mirror and can be employed terrestrially and/or extra-terrestrially.
摘要翻译： 提供玻璃或玻璃陶瓷的整体式基板及其制造方法，其中基板具有轻质结构。 轻质结构包括由腹板限定的凹部，这些腹板形成四角形或四角形的口袋。 由于轻质结构，可以显着地降低基板的重量，同时可以确保高刚性。 衬底可以用作镜子支撑或镜子，并且可以用于地面和/或地面外。
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公开(公告)号：US06853123B1
公开(公告)日：2005-02-08
申请号：US09889099
申请日：2000-01-11
IPC分类号： H01J61/30 , B32B17/10 , C03B17/02 , C03C17/00 , C03C17/30 , C03C17/32 , G02F1/1333 , H01J5/08 , H01J11/00 , H01J17/00 , H01J19/57 , H01J29/86 , H01J29/88 , H01J61/35 , H01J17/49
CPC分类号： B32B17/10577 , B32B17/10018 , C03B17/02 , C03C17/007 , C03C17/30 , C03C17/32 , G02F1/133305 , Y02P40/57
摘要： A flat light source having a front plate and a rear part. The front plate is held at a distance from the rear part by spacers. A gaseous filling which is under a pressure lower than the ambient atmospheric pressure is introduced into the intermediate space between the front plate and rear part, and the front plate is of a glass material. To be able to produce flat light sources of this type which have a low intrinsic weight, according to this invention the front plate and/or the rear part can be configured as an at least partly thermally or chemically tempered glass pane or the front plate and/or the rear part can be configured as a glass pane which at least in areas is coated with ductile polymer material.
摘要翻译： 具有前板和后部的扁平光源。 前板通过间隔件与后部保持一定距离。 在低于环境大气压的压力下的气态填充物被引入到前板和后部之间的中间空间中，前板是玻璃材料。 为了能够生产具有低本征重量的这种类型的平坦光源，根据本发明，前板和/或后部可以构造成至少部分热或化学强化的玻璃板或前板和 /或后部可以被配置为至少在区域中涂覆有延展性聚合物材料的玻璃板。
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