公开(公告)号：US08895190B2

公开(公告)日：2014-11-25

申请号：US12223941

申请日：2007-02-16

申请人： Sung-Kyun Chang ,  Eui-Yong Bang ,  Min-Chul Jang ,  Sang-Hoon Choy ,  Ki-Young Lee ,  Wan-Jae Myeong ,  Kyu-Ho Song ,  Joo-Hyeong Lee ,  Young-Sik Hahn ,  Myung-Ho Cho ,  Yong-Tae Lee

发明人： Sung-Kyun Chang ,  Eui-Yong Bang ,  Min-Chul Jang ,  Sang-Hoon Choy ,  Ki-Young Lee ,  Wan-Jae Myeong ,  Kyu-Ho Song ,  Joo-Hyeong Lee ,  Young-Sik Hahn ,  Myung-Ho Cho ,  Yong-Tae Lee

IPC分类号： H01M4/485 ,  H01M4/88

CPC分类号： H01M4/505 ,  C01G45/1228 ,  C01G51/50 ,  C01G53/50 ,  C01P2002/72 ,  C01P2002/74 ,  C01P2002/86 ,  C01P2004/03 ,  C01P2004/32 ,  C01P2004/61 ,  C01P2006/11 ,  C01P2006/12 ,  C01P2006/13 ,  C01P2006/40 ,  H01M4/485 ,  H01M4/525 ,  H01M10/052 ,  H01M2004/021 ,  Y02P20/544 ,  Y10T29/49108

摘要： Disclosed is a method for preparing a lithium-metal composite oxide, the method comprising the steps of: (a) mixing an aqueous solution of one or more transition metal-containing precursor compounds with an alkalifying agent and a lithium precursor compound to precipitate hydroxides of the transition metals; (b) mixing the mixture of step (a) with water under supercritical or subcritical conditions to synthesize a lithium-metal composite oxide, and drying the lithium-metal composite oxide; and (c) subjecting the dried lithium-metal composite oxide either to calcination or to granulation and then calcination. Also disclosed are an electrode comprising the lithium-metal composite oxide, and an electrochemical device comprising the electrode. In the disclosed invention, a lithium-metal composite oxide synthesized based on the prior supercritical hydrothermal synthesis method is subjected either to calcination or to granulation and then calcination. Thus, unlike the prior dry calcination method or wet precipitation method, a uniform solid solution can be formed and the ordering of metals in the composite oxide can be improved. Accordingly, the lithium-metal composite oxide can show crystal stability and excellent electrochemical properties.

摘要翻译： 公开了一种制备锂金属复合氧化物的方法，该方法包括以下步骤：（a）将一种或多种含过渡金属的前体化合物的水溶液与碱化剂和锂前体化合物混合，以沉淀氢氧化物 过渡金属; （b）在超临界或亚临界条件下将步骤（a）的混合物与水混合以合成锂金属复合氧化物，并干燥该锂金属复合氧化物; 和（c）将干燥的锂金属复合氧化物进行煅烧或造粒，然后煅烧。 还公开了包含锂金属复合氧化物的电极和包含电极的电化学装置。 在所公开的发明中，将基于现有的超临界水热合成方法合成的锂金属复合氧化物进行煅烧或造粒，然后进行煅烧。 因此，与现有的干式煅烧法或湿式沉淀法不同，可以形成均匀的固溶体，并且可以提高复合氧化物中的金属的有序性。 因此，锂 - 金属复合氧化物可以显示出晶体稳定性和优异的电化学性能。

公开(公告)号：US09757482B2

公开(公告)日：2017-09-12

申请号：US13819525

申请日：2011-08-30

申请人： Bong-Sik Jeon ,  Eung Gyu Kim ,  Eun Byul Kwon ,  Ju Young Park ,  Wan Jae Myeong

发明人： Bong-Sik Jeon ,  Eung Gyu Kim ,  Eun Byul Kwon ,  Ju Young Park ,  Wan Jae Myeong

IPC分类号： A61K49/18

CPC分类号： A61K49/1893 ,  A61K49/1824 ,  A61K49/1827 ,  A61K49/1839 ,  A61K49/1857 ,  A61K49/1887

摘要： Provided are iron oxide nanocapsules for an MRI contrast agent having high contrast, in which a plurality of iron oxide nanoparticles having a hydrophobic ligand attached thereto are encapsulated in an encapsulation material including a biodegradable polymer and a surfactant, and which satisfy Relations 1, 2, 3, 4 and 5 below. Also a method of manufacturing the iron oxide nanocapsules is provided. 5≦100*Dμ(IO)/Cω(IO)  [Relation 1] 2.5≦100*Dμ(Cap)/Cω(Cap)  [Relation 2] 0.5 wt %≦F(IO)≦50 wt %  [Relation 3] 1 nm≦Dμ(IO)≦25 nm  [Relation 4] 50 nm≦Dμ(Cap)≦200 nm  [Relation 5]

公开(公告)号：US09028875B2

公开(公告)日：2015-05-12

申请号：US13818734

申请日：2011-08-31

申请人： Eun Byul Kwon ,  Bong-Sik Jeon ,  Eung Gyu Kim ,  Ju Young Park ,  Wan Jae Myeong

发明人： Eun Byul Kwon ,  Bong-Sik Jeon ,  Eung Gyu Kim ,  Ju Young Park ,  Wan Jae Myeong

IPC分类号： A61B5/055 ,  A61K49/18 ,  A61K49/12 ,  B82Y5/00 ,  B01J13/06

CPC分类号： A61K49/1863 ,  A61K49/12 ,  A61K49/126 ,  A61K49/128 ,  A61K49/1818 ,  A61K49/1827 ,  A61K49/1851 ,  B01J13/06 ,  B82Y5/00

摘要： Provided is an iron oxide nanocapsule which has extremely excellent water dispersibility, which is very stable in the body and which has very excellent MRI contrast ability, a method of manufacturing the same, and an MRI contrast agent using the same. The method of manufacturing the iron oxide nanocapsule includes the steps of: thermally decomposing an iron complex to prepare hydrophobic ligand-bonded iron oxide nanoparticles; and encapsulating the hydrophobic ligand-bonded iron oxide nanoparticles by a carboxymethyldextrandodecylamine conjugate encapsulation material or a dextran-linoleic acid conjugate encapsulation material to form an iron oxide nanocapsule.

摘要翻译： 本发明提供一种氧化铁纳米胶囊，其具有非常优异的水分散性，其在体内非常稳定，具有非常优异的MRI对比能力，其制造方法和使用其的MRI造影剂。 制造氧化铁纳米胶囊的方法包括以下步骤：热分解铁络合物以制备疏水配体键合的氧化铁纳米颗粒; 并用羧甲基十四烷基胺偶联剂包封材料或葡聚糖 - 亚油酸共轭物包封材料封装疏水配体键合的氧化铁纳米颗粒，以形成氧化铁纳米胶囊。

公开(公告)号：US08906346B2

公开(公告)日：2014-12-09

申请号：US14000301

申请日：2012-06-20

申请人： Ju Young Park ,  Wan Jae Myeong ,  Bong-Sik Jeon ,  Eung Gyu Kim ,  Eun Byul Kwon ,  Taeghwan Hyeon ,  Daishun Ling

发明人： Ju Young Park ,  Wan Jae Myeong ,  Bong-Sik Jeon ,  Eung Gyu Kim ,  Eun Byul Kwon ,  Taeghwan Hyeon ,  Daishun Ling

IPC分类号： A61K49/04 ,  A61K49/12 ,  A61K49/18 ,  B82Y15/00

CPC分类号： A61K49/124 ,  A61K49/1857 ,  A61K49/186 ,  B82Y15/00

摘要： Provided are a contrast agent for contrast imaging lymph node, which includes iron oxide nanoparticles dispersed and stabilized in an aqueous medium by a mussel adhesive protein-mimetic copolymer, a method for contrast enhanced lymphography using the foregoing contrast agent, and a method for diagnosis of lymph node cancers using the foregoing contrast agent. Using such a mussel adhesive protein-mimetic copolymer, the surface of iron oxide is modified and dispersed well in water to prepare a colloidal solution, which in turn forms the contrast agent containing the colloidal solution. The inventive contrast agent does not have toxicity and is easily taken up to the lymph node to exhibit excellent contrast imaging effects. The contrast agent of the present invention is useful for diagnosis of metastatic cancers.

摘要翻译： 本发明提供对比成像淋巴结的造影剂，其包括通过贻贝粘合蛋白模拟共聚物在水性介质中分散和稳定的氧化铁纳米颗粒，使用前述造影剂的对比度增强淋巴造影术的方法和诊断方法 使用上述造影剂的淋巴结癌。 使用这种贻贝粘合蛋白模拟共聚物，将氧化铁的表面改性并充分分散在水中以制备胶体溶液，这又形成含有胶体溶液的造影剂。 本发明的造影剂不具有毒性，并且容易吸收到淋巴结以显示出优异的对比度成像效果。 本发明的造影剂可用于诊断转移性癌症。

公开(公告)号：US20100230651A1

公开(公告)日：2010-09-16

申请号：US12661119

申请日：2010-03-10

申请人： Wan-Jae Myeong ,  Kyu-Ho Song ,  Se-Woong Park ,  Joo-Hyeong Lee ,  Jin-Soo Baik ,  Chang-Mo Chung

发明人： Wan-Jae Myeong ,  Kyu-Ho Song ,  Se-Woong Park ,  Joo-Hyeong Lee ,  Jin-Soo Baik ,  Chang-Mo Chung

IPC分类号： F21V9/06 ,  C09K3/00

CPC分类号： C01G25/02 ,  A61K8/044 ,  A61K2800/413 ,  A61Q17/04 ,  B82Y5/00 ,  B82Y30/00 ,  C01B13/0262 ,  C01B13/366 ,  C01B2210/0046 ,  C01F17/0043 ,  C01G1/02 ,  C01G9/00 ,  C01G9/02 ,  C01G25/00 ,  C01P2002/50 ,  C01P2002/60 ,  C01P2002/84 ,  C01P2004/64 ,  C01P2006/12 ,  C01P2006/13 ,  C01P2006/40 ,  Y02P20/544

摘要： Disclosed is a method for preparing a metal oxide solid solution in nano size. The metal oxide solid solution is prepared by reacting a reactant mixture containing water and at least two water-soluble metal compounds at 200 to 700° C. under a pressure of 180 to 550 bar in a continuous manner, wherein the reactant mixture contains the metal compounds at an amount of 0.01 to 30% by weight in total and the solid solution has a crystallite size of 1 to 1,000 nm. The metal oxide solid solution is, in particular suitable as a UV light shielding agent or as an oxygen storage component.

摘要翻译： 公开了一种制备纳米尺寸金属氧化物固溶体的方法。 金属氧化物固溶体是通过使反应混合物含有水和至少两种水溶性金属化合物在200-700℃下以180-550巴的压力连续地进行反应来制备的，其中反应物混合物含有金属 化合物的总量为0.01〜30重量％，固溶体的微晶尺寸为1〜1000nm。 金属氧化物固溶体特别适合作为紫外线遮光剂或作为储氧组分。

公开(公告)号：US07754168B2

公开(公告)日：2010-07-13

申请号：US10557940

申请日：2004-05-21

申请人： Se-Woong Park ,  Wan-Jae Myeong ,  Jin-Soo Baik ,  Chang-Mo Chung ,  Kyu-Ho Song

发明人： Se-Woong Park ,  Wan-Jae Myeong ,  Jin-Soo Baik ,  Chang-Mo Chung ,  Kyu-Ho Song

IPC分类号： C01F17/00 ,  B24D3/00

CPC分类号： C09K3/1463 ,  B82Y30/00 ,  C01F17/0043 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/12 ,  C01P2006/80 ,  C01P2006/90 ,  C03C19/00 ,  C09K3/1409

摘要： Disclosed are a concentrate of fine ceria particles for chemical mechanical polishing, and a method of preparing the same. The method includes reacting a reactant mixture comprising i) water, ii) an aqueous solution of water-soluble cerium salt compound, and iii) ammonia or ammonium salt at a reaction temperature of 250-700? under a reaction pressure of 180-550 bar for 0.01 sec to 10 min in a continuous reactor to obtain a solution containing the fine ceria particles, the cerium salt compound being contained at an amount of 0.01 to 20 wt % in the reactant mixture; and concentrating the solution containing the fine ceria particles in a concentrator having a filter with a pore size of 0.01 to 10?. The concentrate is advantageous in that a CMP slurry and a dispersing solution are easily produced by diluting the concentrate and adding an additive to the concentrate.

摘要翻译： 公开了用于化学机械抛光的精细二氧化铈微粒的浓缩物及其制备方法。 该方法包括使反应混合物反应，该反应混合物包括：i）水，ii）水溶性铈盐化合物的水溶液，和iii）氨或铵盐，反应温度为250-700℃， 在连续反应器中在180-550巴的反应压力下进行0.01秒至10分钟，以获得含有细小二氧化铈颗粒的溶液，所述铈盐化合物在反应物混合物中的含量为0.01-20重量％; 并将含有细小二氧化铈颗粒的溶液浓缩在具有孔径为0.01至10埃的过滤器的浓缩器中。 浓缩物的优点在于通过稀释浓缩物并向浓缩物中加入添加剂容易地制备CMP浆料和分散溶液。

公开(公告)号：US20070212289A1

公开(公告)日：2007-09-13

申请号：US10557940

申请日：2004-05-21

申请人： Se-Woong Park ,  Wan-Jae Myeong ,  Jin-Soo Baik ,  Chang-Mo Chung

发明人： Se-Woong Park ,  Wan-Jae Myeong ,  Jin-Soo Baik ,  Chang-Mo Chung

IPC分类号： C01F17/00

CPC分类号： C09K3/1463 ,  B82Y30/00 ,  C01F17/0043 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/12 ,  C01P2006/80 ,  C01P2006/90 ,  C03C19/00 ,  C09K3/1409

摘要： Disclosed are a concentrate of fine ceria particles for chemical mechanical polishing, and a method of preparing the same. The method includes reacting a reactant mixture comprising i) water, ii) an aqueous solution of water-soluble cerium salt compound, and iii) ammonia or ammonium salt at a reaction temperature of 250-700 ? under a reaction pressure of 180-550 bar for 0.01 sec to 10 min in a continuous reactor to obtain a solution containing the fine ceria particles, the cerium salt compound being contained at an amount of 0.01 to 20 wt % in the reactant mixture; and concentrating the solution containing the fine ceria particles in a concentrator having a filter with a pore size of 0.01 to 10 ?. The concentrate is advantageous in that a CMP slurry and a dispersing solution are easily produced by diluting the concentrate and adding an additive to the concentrate.

摘要翻译： 公开了用于化学机械抛光的精细二氧化铈微粒的浓缩物及其制备方法。 该方法包括使反应混合物反应，该反应混合物包括：i）水，ii）水溶性铈盐化合物的水溶液，和iii）氨或铵盐，反应温度为250-700℃， 在连续反应器中在180-550巴的反应压力下进行0.01秒至10分钟，以获得含有细小二氧化铈颗粒的溶液，所述铈盐化合物在反应物混合物中的含量为0.01-20重量％; 并将含有细小二氧化铈颗粒的溶液浓缩在具有孔径为0.01至10 6的过滤器的浓缩器中。 浓缩物的优点在于通过稀释浓缩物并向浓缩物中加入添加剂容易地制备CMP浆料和分散溶液。

公开(公告)号：US07235224B2

公开(公告)日：2007-06-26

申请号：US10521642

申请日：2003-07-08

申请人： Wan-Jae Myeong ,  Jin-Soo Baik ,  Se-Woong Park ,  Chang-Mo Chung ,  Kyu-Ho Song

发明人： Wan-Jae Myeong ,  Jin-Soo Baik ,  Se-Woong Park ,  Chang-Mo Chung ,  Kyu-Ho Song

IPC分类号： C01G1/00

CPC分类号： C01G49/0036 ,  B82Y30/00 ,  C01B13/366 ,  C01F17/0043 ,  C01G1/02 ,  C01G9/02 ,  C01G51/42 ,  C01P2004/20 ,  C01P2004/41 ,  C01P2004/62 ,  C01P2004/64 ,  Y02P20/544 ,  Y10S977/773 ,  Y10S977/775 ,  Y10S977/811

摘要： Disclosed is a process for preparing fine metal oxide particles, comprising the following steps of reacting a reactant mixture comprising i) water, ii) at least one water-soluble metal nitrate and iii) ammonia or ammonium salt at 250–700° C. under 180–550 bar for 0.01 sec to 10 min in a reaction zone to synthesize the metal oxide particles, the metal nitrate being contained at an amount of 0.01–20 wt % in the reactant mixture; and separating and recovering the metal oxide particles from the resulting reaction products. According to the present invention, nano-sized metal oxide particles are synthesized, while the harmful by-products generated concurrently therewith are effectively decomposed in the same reactor.

摘要翻译： 公开了一种制备金属氧化物微粒的方法，包括以下步骤：使反应物混合物反应，所述反应物混合物包含i）水，ii）至少一种水溶性金属硝酸盐和iii）氨或铵盐，在250-700℃下 180-550巴在反应区中0.01秒至10分钟以合成金属氧化物颗粒，在反应混合物中含有0.01-20重量％的金属硝酸盐; 并从所得反应产物中分离和回收金属氧化物颗粒。 根据本发明，合成纳米尺寸金属氧化物颗粒，同时产生的有害副产物在同一反应器中有效分解。

公开(公告)号：US20070042526A1

公开(公告)日：2007-02-22

申请号：US10557939

申请日：2004-05-21

申请人： Wan-Jae Myeong ,  Kyu-Ho Song ,  Se-Woong Park ,  Joo-Hyeong Lee ,  Jin-Soo Baik ,  Chang-Mo Chung

发明人： Wan-Jae Myeong ,  Kyu-Ho Song ,  Se-Woong Park ,  Joo-Hyeong Lee ,  Jin-Soo Baik ,  Chang-Mo Chung

IPC分类号： H01L21/16 ,  H01L21/00

CPC分类号： C01G25/02 ,  A61K8/044 ,  A61K2800/413 ,  A61Q17/04 ,  B82Y5/00 ,  B82Y30/00 ,  C01B13/0262 ,  C01B13/366 ,  C01B2210/0046 ,  C01F17/0043 ,  C01G1/02 ,  C01G9/00 ,  C01G9/02 ,  C01G25/00 ,  C01P2002/50 ,  C01P2002/60 ,  C01P2002/84 ,  C01P2004/64 ,  C01P2006/12 ,  C01P2006/13 ,  C01P2006/40 ,  Y02P20/544

摘要： Disclosed is a method for preparing a metal oxide solid solution in nano size. The metal oxide solid solution is prepared by reacting a reactant mixture containing water and at least two water-soluble metal compounds at 200 to 700° C. under a pressure of 180 to 550 bar in a continuous manner, wherein the reactant mixture contains the metal compounds at an amount of 0.01 to 30% by weight in total and the solid solution has a crystallite size of 1 to 1,000 nm. The metal oxide solid solution is, in particular suitable as a UV light shielding agent or as an oxygen storage component.

摘要翻译： 公开了一种制备纳米尺寸金属氧化物固溶体的方法。 金属氧化物固溶体是通过使反应混合物含有水和至少两种水溶性金属化合物在200-700℃下以180-550巴的压力连续地进行反应来制备的，其中反应物混合物含有金属 化合物的总量为0.01〜30重量％，固溶体的微晶尺寸为1〜1000nm。 金属氧化物固溶体特别适合作为紫外线遮光剂或作为储氧组分。

公开(公告)号：US20140328768A1

公开(公告)日：2014-11-06

申请号：US13818734

申请日：2011-08-31

申请人： Eun Byul Kwon ,  Bong Sik Jeon ,  Eung Gyu Kim ,  Ju Young Park ,  Wan Jae Myeong

发明人： Eun Byul Kwon ,  Bong Sik Jeon ,  Eung Gyu Kim ,  Ju Young Park ,  Wan Jae Myeong

IPC分类号： A61K49/18 ,  B01J13/06

CPC分类号： A61K49/1863 ,  A61K49/12 ,  A61K49/126 ,  A61K49/128 ,  A61K49/1818 ,  A61K49/1827 ,  A61K49/1851 ,  B01J13/06 ,  B82Y5/00

摘要： Provided is an iron oxide nanocapsule which has extremely excellent water dispersibility, which is very stable in the body and which has very excellent MRI contrast ability, a method of manufacturing the same, and an MRI contrast agent using the same. The method of manufacturing the iron oxide nanocapsule includes the steps of: thermally decomposing an iron complex to prepare hydrophobic ligand-bonded iron oxide nanoparticles; and encapsulating the hydrophobic ligand-bonded iron oxide nanoparticles by a carboxymethyldextrandodecylamine conjugate encapsulation material or a dextran-linoleic acid conjugate encapsulation material to form an iron oxide nanocapsule.

摘要翻译： 本发明提供一种氧化铁纳米胶囊，其具有非常优异的水分散性，其在体内非常稳定，具有非常优异的MRI对比能力，其制造方法和使用其的MRI造影剂。 制造氧化铁纳米胶囊的方法包括以下步骤：热分解铁络合物以制备疏水配体键合的氧化铁纳米颗粒; 并用羧甲基十四烷基胺偶联剂包封材料或葡聚糖 - 亚油酸共轭物包封材料封装疏水配体键合的氧化铁纳米颗粒，以形成氧化铁纳米胶囊。