摘要:
The invention provides crystalline solid forms of (((S)-1-{(S)-2-[4-(4′-{[6-((2R,5S)-2,5-dimethyl-4-methylcarbamoyl-piperazin-1-yl)-pyridine-3-carbonyl]-amino}-2′-trifluoromethoxy-biphenyl-4-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat hepatitis C virus infection, and processes useful for preparing such crystalline solid forms.
摘要:
A new process and structure for microcomponent interconnection utilizing a post-assembly activated junction compound. In one embodiment, first and second microcomponents having respective first and second contact areas are provided. A junction compound is formed on one of the first and second contact areas, and the first and second contact areas are positioned adjacent each other on opposing sides of the junction compound. The junction compound is then activated to couple the first and second microcomponents.
摘要:
A method for determining formation shear slowness of formations surrounding an earth borehole that includes: transmitting sonic energy into the formations from a dipole source in the borehole; measuring signals from orthogonal wave components that have traveled through the formations at each of a plurality of receiver locations in the borehole, spaced at a respective plurality of distances from the transmitter location; transforming the signals to the frequency domain and separating dispersive and non-dispersive portions of the transformed signals; and determining fast and slow shear slowness of the formation from the low frequency asymptotes of the dispersive portions of the transformed signals. Related methods for determining shear directionality and the magnitude of anisotropy of anisotropic formations surrounding an earth borehole and associated apparatus are also described.
摘要:
The invention provides crystalline solid forms of (((S)-1-{(S)-2-[4-(4′-{[6-((2R,5S)-2,5-dimethyl-4-methylcarbamoyl-piperazin-1-yl)-pyridine-3-carbonyl]-amino}-2′-trifluoromethoxy-biphenyl-4-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat hepatitis C virus infection, and processes useful for preparing such crystalline solid forms.
摘要:
The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.
摘要:
A digital content counting system and a method thereof are provided for achieving the credible transaction counting mechanism established between the owner of copyrights and the seller, to make the owner of copyrights and the seller collectively confirm the transaction information of the digital contents. The system comprises a sale subsystem, an authorization service subsystem and a transaction clearing subsystem; the sale subsystem and the authorization service subsystem authenticate each other; the transaction clearing subsystem and the authorization service subsystem authenticate each other; the transaction clearing subsystem authenticates the sale subsystem; the sale subsystem generates transaction request information according to a purchase list, sends the transaction request information to the authenticated authorization service subsystem, and records transaction success information; after receiving and confirming the transaction request information, the authorization service subsystem sends transaction success information to a client device, the sale subsystem and authenticated transaction clearing subsystem, sends an approach for obtaining an authorization file to the client device, records the transaction request information, and issues the authorization file; the transaction clearing subsystem records the transaction success information.
摘要:
A method and apparatus for estimating the slowness of a geological formation using waveforms recorded by an acoustic borehole logging tool. Phase slowness coherence is extracted from the recorded waveforms after transformation to the frequency domain (804) at various frequencies (806), and this is converted into a formation slowness curve (808) which can be used as an objective function from which an anomaly, such as a local maximum or minimum (810), can be identified as representative of an estimate of the formation slowness.
摘要:
The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.
摘要:
Method and system for displaying activities of friends. The method includes, generating activity information from the activities of friends according to the friend relationship chain; classifying the activity information according to the preset classification rule to obtain the corresponding classification collection; acquiring the screening condition, extracting activity information that meets the screening condition from the classification collection, and displaying the activity information extracted. According to the method and system, through the classification and screening of activity information, the activities of friends which meet screening conditions entered by a user can be obtained and displayed. Using this method and the system, a large amount of information can be quickly screened and all the friends' effective activities can be provided to the user allowing user to achieve personalized browsing.
摘要:
Multi-level structures are formed in a semiconductor substrate by first forming a pattern of lines or structures of different widths. Width information on the pattern is decoded by processing steps into level information to form a MEMS structure. The pattern is etched to form structures having a first floor. The structures are oxidized until structures of thinner width are substantially fully oxidized. A portion of the oxide is then etched to expose the first floor. The first floor is then etched to form a second floor. The oxide is then optionally removed, leaving a multi-level structure. In one embodiment, high aspect ratio comb actuators are formed using the multi-level structure process.