公开(公告)号：US20100247909A1

公开(公告)日：2010-09-30

申请号：US11647863

申请日：2006-12-29

Applicant: Younghee Lee ,  Kayhyeok An ,  Eunju Ra

Inventor： Younghee Lee ,  Kayhyeok An ,  Eunju Ra

IPC: D02G3/02 ,  D01F9/12 ,  B29C47/36

CPC classification number: D01F1/08 ,  D01D5/0038 ,  D01F9/14 ,  Y10T428/2918

Abstract: The present invention provides a process for manufacturing a carbon nanofiber comprising: (a) mixing a carbon nanofiber precursor and camphor in a solvent to prepare a solution; (b) electric spinning the solution to obtain a nanofiber; (c) oxidative stabilizing the nanofiber; and (d) carbonizing the oxidative stabilized nanofiber, wherein camphor is volatilized to form micropores in the oxidative stabilization and carbonization. The present invention also provides a carbon nanofiber manufactured by the same.

Abstract translation: 本发明提供一种制造碳纳米纤维的方法，包括：（a）将碳纳米纤维前体和樟脑在溶剂中混合以制备溶液; （b）电解纺丝以获得纳米纤维; （c）氧化稳定纳米纤维; 和（d）将氧化稳定的纳米纤维碳化，其中樟脑在氧化稳定化和碳化中挥发以形成微孔。 本发明还提供一种由其制造的碳纳米纤维。

公开(公告)号：US20090093479A1

公开(公告)日：2009-04-09

申请号：US12336857

申请日：2008-12-17

Applicant: Martha KELLY ,  Younghee LEE ,  Bin LIU ,  Ted FUJIMOTO ,  Joel FREUNDLICH ,  Bruce D. DORSEY ,  Gary A. FLYNN ,  Arifa HUSAIN

Inventor： Martha KELLY ,  Younghee LEE ,  Bin LIU ,  Ted FUJIMOTO ,  Joel FREUNDLICH ,  Bruce D. DORSEY ,  Gary A. FLYNN ,  Arifa HUSAIN

IPC: A61K31/5377 ,  C07D401/02 ,  C07D211/80 ,  C07D409/02 ,  C07D401/14 ,  C07D405/02 ,  A61K31/497 ,  A61K31/506 ,  A61P35/00 ,  A61K31/422 ,  A61K31/4709 ,  A61K31/4439 ,  A61K31/4436 ,  A61K31/443 ,  A61K31/44 ,  C07D413/02

CPC classification number: C07D209/08 ,  C07D213/74 ,  C07D401/10 ,  C07D401/12 ,  C07D401/14 ,  C07D403/10 ,  C07D403/12 ,  C07D405/10 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D417/10

Abstract: The present invention is in the area of novel compounds and salts thereof, their syntheses, and their use as anti-cancer agents. The compounds include compounds of Formula I: and solvates, hydrates and pharmaceutically-acceptable salts thereof, wherein A1 is N or CR1; A3 is N or CR3; A5 is N or CR5; R1, R3-R6 and L are defined in the specification; n is 0 or 1; and X is an optionally-substituted aryl group having 6-10 carbons in the ring portion, an optionally-substituted 6-membered heteroaryl group having 1-3 nitrogen atoms in the ring portion, an optionally-substituted 5-membered heteroaryl group having 0-4 nitrogen atoms in the ring portion and optionally having 1 sulfur atom or 1 oxygen atom in the ring portion, or an optionally-substituted heteroaryl group in which a 6-membered ring is fused either to a 5-membered ring or to a 6-membered ring, wherein in each case 1, 2, 3 or 4 ring atoms are heteroatoms independently selected from nitrogen, oxygen and sulfur. They are effective against a broad range of cancers, especially leukemia, non-small cell lung and colon.

Abstract translation: 本发明涉及新型化合物及其盐，其合成及其作为抗癌剂的用途。 化合物包括式I化合物及其溶剂合物，水合物及其药学上可接受的盐，其中A1为N或CR1; A3是N或CR3; A5为N或CR5; R1，R3-R6和L在说明书中定义; n为0或1; 并且X是在环部分中具有6-10个碳的任选取代的芳基，在环部分中具有1-3个氮原子的任选取代的6元杂芳基，任选取代的5元杂芳基具有0 -4个氮原子，并且在环部分中任选具有1个硫原子或1个氧原子，或任选取代的杂芳基，其中6元环稠合到5元环或6元环 其中在每种情况下，1,2,3或4个环原子是独立地选自氮，氧和硫的杂原子。 它们对广泛的癌症尤其是白血病，非小细胞肺和结肠有效。

公开(公告)号：US20150090247A1

公开(公告)日：2015-04-02

申请号：US14348890

申请日：2013-10-01

Applicant: Younghee Lee

Inventor： Younghee Lee

IPC: F24C15/20

CPC classification number: F24C15/2014 ,  F24C14/025 ,  F24C15/322

Abstract: The cooking device with pyrolysis function includes a cooking cavity, a heating means located within the cooking cavity for emitting heat, a combustion tube having a hollow portion formed to surround the heating means, the combustion tube being heated by the heating means and radiates its heat to the center of the cooking cavity, a combustion space formed between the heating means and the combustion tube in which cooking fumes are decomposed by the heat from the heating means, a fan adapted to withdraw air from the cooking cavity and to discharge a part or ail of the air through the connection tube into the combustion space, a connection tube for connecting fluid communication between the combustion tube and the fan, and a gas outlet for venting the steam and air in the combustion space to the outside of the cooking device.

Abstract translation: 具有热分解功能的烹调装置包括烹饪腔，位于烹饪腔内用于发热的加热装置，具有形成为围绕加热装置的中空部分的燃烧管，燃烧管由加热装置加热并辐射其热量 到烹饪腔的中心，形成在加热装置和燃烧管之间的燃烧空间，其中烹饪烟雾通过来自加热装置的热分解，风扇，其适于从烹饪腔抽出空气并排出部分， 空气通过连接管进入燃烧空间，用于连接燃烧管和风扇之间的流体连通的连接管和用于将燃烧空间中的蒸汽和空气排放到烹饪装置的外部的气体出口。

公开(公告)号：US08962623B2

公开(公告)日：2015-02-24

申请号：US14001936

申请日：2012-02-29

Applicant: Rupa S. Shetty ,  Martha J. Kelly ,  Bin Liu ,  Jinming Zou ,  Kristofer K. Moffett ,  Younghee Lee ,  Dora Do-York Wong

Inventor： Rupa S. Shetty ,  Kevin J. Moriarity ,  Martha J. Kelly ,  Bin Liu ,  Jinming Zou ,  Kristofer K. Moffett ,  Younghee Lee

IPC: A61K31/5377 ,  C07D487/04 ,  C07D491/056 ,  C07D401/12 ,  C07D413/14 ,  C07D403/12 ,  C07D401/14 ,  C07D407/14 ,  C07D409/14 ,  C07D417/14

CPC classification number: C07D413/14 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D407/14 ,  C07D409/14 ,  C07D417/14 ,  C07D487/04 ,  C07D491/056

Abstract: A compound of formula (I): wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has an Itk inhibitory activity, and is useful as a method for preventing and/or treating atopic dermatitis, and the like.

Abstract translation: 式（I）的化合物：其中所有符号具有与说明书中定义的相同的含义; 其盐，其溶剂合物，N-氧化物或其前药具有Itk抑制活性，可用作预防和/或治疗特应性皮炎等的方法。

公开(公告)号：US06416861B1

公开(公告)日：2002-07-09

申请号：US09504217

申请日：2000-02-15

Applicant: Younghee Lee ,  Richard B. Silverman

Inventor： Younghee Lee ,  Richard B. Silverman

IPC: B32B2520

CPC classification number: C07F7/0812 ,  C07B2200/11 ,  C07F7/081 ,  C40B40/00 ,  Y10T428/2962 ,  Y10T428/2995

Abstract: A compound of the formula: and a resin-bound compound of the formula: and their use in combinatorial chemistry and in the synthesis of compounds comprising at least one aromatic moiety is described, where R1, R2, R3, R4, R5, R6, R7, L1, P, Ar1, and X are as herein defined.

Abstract translation: 描述了下式的化合物和下式的树脂结合化合物及其在组合化学中的用途和合成含有至少一个芳族部分的化合物，其中R 1，R 2，R 3，R 4，R 5，R 6， R7，L1，P，Ar1和X如本文所定义。

公开(公告)号：US09644849B2

公开(公告)日：2017-05-09

申请号：US14348613

申请日：2012-11-15

Applicant: Younghee Lee

Inventor： Younghee Lee

IPC: F24C15/20 ,  F24C15/32 ,  F24C14/02

CPC classification number: F24C15/327 ,  F24C14/02 ,  F24C15/2014

Abstract: The oven having combustion function includes a cooking cavity; a heating means for emitting heat; a combustion tube for surrounding the heating means, and the combustion tube also being in fluid communication with the cooking cavity and a flow supply unit; a combustion space wherein odor-producing materials are removed by the heat from the heating means, the combustion space formed between the heating means and the combustion tube; a flow supply unit connected to the combustion tube for developing a flow of air through the combustion space; and a connection tube for connecting the flow supply unit to the combustion tube. The odor-producing materials are pyrolyzed by staying at least 0.5 seconds in the combustion space heated over 700° C. The oven has high energy efficiency since the heating means carries out thermal decomposition of the odor-producing materials and heats food by supplying radiant heat to the cooking cavity.

公开(公告)号：US20140238381A1

公开(公告)日：2014-08-28

申请号：US14348613

申请日：2012-11-15

Applicant: Younghee Lee

Inventor： Younghee Lee

IPC: F24C15/20 ,  F24C15/32

CPC classification number: F24C15/327 ,  F24C14/02 ,  F24C15/2014

Abstract: The oven having combustion function includes a cooking cavity; a heating means for emitting heat; a combustion tube for surrounding the heating means, and the combustion tube also being in fluid communication with the cooking cavity and a flow supply unit; a combustion space wherein odor-producing materials are removed by the heat from the heating means, the combustion space formed between the heating means and the combustion tube; a flow supply unit connected to the combustion tube for developing a flow of air through the combustion space; and a connection tube for connecting the flow supply unit to the combustion tube. The odor-producing materials are pyrolyzed by staying at least 0.5 seconds in the combustion space heated over 700° C. The oven has high energy efficiency since the heating means carries out thermal decomposition of the odor-producing materials and heats food by supplying radiant heat to the cooking cavity

Abstract translation: 具有燃烧功能的烤箱包括烹饪腔; 用于发热的加热装置; 用于围绕加热装置的燃烧管，并且燃烧管也与烹饪腔体和流动供应单元流体连通; 燃烧空间，其中产生气味的材料通过来自加热装置的热量，在加热装置和燃烧管之间形成的燃烧空间被去除; 连接到燃烧管的流动供应单元，用于产生通过燃烧空间的空气流; 以及用于将流动供应单元连接到燃烧管的连接管。 产生气味的材料通过在加热至700℃的燃烧空间中保持至少0.5秒而被热解。由于加热装置进行产生气味的材料的热分解并且通过提供辐射热来加热食物，炉具有高能量效率 到烹饪腔

公开(公告)号：US08765754B2

公开(公告)日：2014-07-01

申请号：US13266921

申请日：2010-04-28

Applicant: Zenon Konteatis ,  Kristofer Moffett ,  Younghee Lee ,  Wenchun Chao ,  Dora Do-York Wong

Inventor： Kevin J. Moriarty ,  Zenon Konteatis ,  Kristofer Moffett ,  Younghee Lee ,  Wenchun Chao

IPC: A01N43/64 ,  A61K31/53 ,  C07D487/00

CPC classification number: A61K31/53 ,  C07D487/04 ,  A61K2300/00

Abstract: A compound of formula (I): wherein all symbols have the same meanings as defined in the specification; a salt thereof, a solvate thereof, an N-oxide thereof, or a prodrug thereof, has a Btk inhibitory activity, and is useful as a method for preventing and/or treating a rheumatoid arthritis, an autoimmune disease, a B cell lymphoma of cancer, and the like.

Abstract translation: 式（I）的化合物：其中所有符号具有与说明书中定义的相同的含义; 其盐，其溶剂合物，N-氧化物或其前药具有Btk抑制活性，并且可用作预防和/或治疗类风湿性关节炎，自身免疫疾病，B细胞淋巴瘤的B细胞淋巴瘤 癌症等。

公开(公告)号：US07741479B2

公开(公告)日：2010-06-22

申请号：US11295638

申请日：2005-12-07

Applicant: Enrique Luis Michelotti ,  Eric Bruce Springman ,  Duyan Nguyen ,  Rupa S. Shetty ,  Younghee Lee ,  Kristofer Kent Moffett ,  Jennifer Lee Ludington ,  Ted Tsutomis Fujimoto ,  Zenon D. Konteatis ,  Bin Liu ,  Frank Hollinger ,  Bruce D. Dorsey

Inventor： Enrique Luis Michelotti ,  Eric Bruce Springman ,  Duyan Nguyen ,  Rupa S. Shetty ,  Younghee Lee ,  Kristofer Kent Moffett ,  Jennifer Lee Ludington ,  Ted Tsutomis Fujimoto ,  Zenon D. Konteatis ,  Bin Liu ,  Frank Hollinger ,  Bruce D. Dorsey

IPC: C07D273/06

CPC classification number: C07D333/38 ,  C07D231/40 ,  C07D243/08 ,  C07D277/48 ,  C07D277/56 ,  C07D295/192 ,  C07D333/36 ,  C07D403/06 ,  C07D405/06 ,  C07D409/04 ,  C07D409/06 ,  C07D409/12 ,  C07D413/12 ,  C07D413/14 ,  C07D417/06 ,  C07D417/14 ,  C07D495/04

Abstract: The present invention is directed to a compound having the formula wherein R1, R2, G, and Q are defined herein. The compounds of the present invention are useful as inhibitors of protein kinases such as MAP kinases, in particular p38 kinases. The present invention is also directed to compositions comprising a compound according to the above formula. The compounds and compositions described herein are useful for treating and preventing an inflammatory condition or disease. The present invention is also directed to a method of treating or preventing a protein kinase-mediated condition.

Abstract translation: 本发明涉及具有下式的化合物：其中R1，R2，G和Q如本文所定义。 本发明的化合物可用作蛋白激酶如MAP激酶，特别是p38激酶的抑制剂。 本发明还涉及包含根据上式的化合物的组合物。 本文所述的化合物和组合物可用于治疗和预防炎性疾病或疾病。 本发明还涉及治疗或预防蛋白激酶介导的病症的方法。

公开(公告)号：US07641883B2

公开(公告)日：2010-01-05

申请号：US12062613

申请日：2008-04-04

Applicant: Hyeon Jin Shin ,  Seonmi Yoon ,  Jaeyoung Choi ,  Seong Jae Choi ,  YoungHee Lee ,  JungJun Bae

Inventor： Hyeon Jin Shin ,  Seonmi Yoon ,  Jaeyoung Choi ,  Seong Jae Choi ,  YoungHee Lee ,  JungJun Bae

IPC: D01F9/12 ,  B03B1/04 ,  B01D11/04 ,  H01B1/04

CPC classification number: B82Y30/00 ,  B82Y40/00 ,  C01B32/172 ,  C01B32/174 ,  C01B2202/22 ,  C01B2202/28 ,  Y10S977/751 ,  Y10S977/895

Abstract: The separation of carbon nanotubes into metallic carbon nanotubes and semiconducting carbon nanotubes is made to be possible simultaneously with the dispersion of the carbon nanotubes by using viologen.

Abstract translation: 将碳纳米管分离成金属碳纳米管和半导体碳纳米管可以通过使用紫精与碳纳米管的分散同时进行。