Method of treating amykloidosis comprising administering an anti-HMGB-1 antibody
    1.
    发明授权
    Method of treating amykloidosis comprising administering an anti-HMGB-1 antibody 失效
    治疗淀粉样变性的方法,包括施用抗HMGB-1抗体

    公开(公告)号:US08470325B2

    公开(公告)日:2013-06-25

    申请号:US12449543

    申请日:2008-02-15

    CPC classification number: C07K16/24 C07K2317/21 C07K2317/23 C07K2317/76

    Abstract: Previously, it was difficult to obtain high-affinity antibodies that specifically bind to HMGB-1 but not to HMGB-2. Under this circumstance, the present inventors successfully obtained antibodies that are more reactive to HMGB-1 than to HMGB-2 by using specific peptides as an antigen. The present inventors also demonstrated that the antibodies had a HMGB-1-neutralizing activity. The present inventors administered the antibodies to amyloidosis model animals, and as a result, successfully demonstrated that the antibodies produced a significant therapeutic effect.

    Abstract translation: 以前,难以获得特异性结合HMGB-1但不与HMGB-2结合的高亲和力抗体。 在这种情况下,通过使用特定的肽作为抗原,本发明人成功地获得了比HMGB-2更能反应HMGB-1的抗体。 本发明人还证明了抗体具有HMGB-1-中和活性。 本发明人给淀粉样变性模型动物施用抗体,结果证明抗体产生显着的治疗效果。

    Printing apparatus with movable head device for ejecting ink
    2.
    发明授权
    Printing apparatus with movable head device for ejecting ink 有权
    具有用于喷射墨水的可动头装置的打印装置

    公开(公告)号:US08047646B2

    公开(公告)日:2011-11-01

    申请号:US12198590

    申请日:2008-08-26

    CPC classification number: B41J3/28 B41J3/4078 B41J11/06 Y10S428/914

    Abstract: A printing apparatus including a conveyer system configured to convey a pallet having a print substrate thereon, anteroposterior moving mechanisms, fitting members disposed on the moving mechanisms, a guide bar member that extends in a lateral direction mounted on the fitting members, and a head device that is movably disposed along the guide bar member and has a plurality of inkjet nozzles. The printing apparatus is adapted to conduct printing by ejecting ink droplets from the inkjet nozzles to the print substrate on the pallet which is secured above an upper conveying passage and which is conveyed by the conveyer system while moving the head device.

    Abstract translation: 一种打印装置,包括:输送机系统,被配置为输送其上具有打印基板的托盘;前后移动机构;设置在所述移动机构上的装配构件;沿着安装在所述装配构件上的横向方向延伸的导杆构件;以及头装置 其沿着导杆构件可移动地设置并且具有多个喷墨喷嘴。 打印装置适于通过将墨滴从喷墨喷嘴喷射到固定在上输送通道上方的托盘上的打印基板,并且在移动头装置的同时由输送系统输送。

    PRINTING APPARATUS
    3.
    发明申请
    PRINTING APPARATUS 有权
    打印设备

    公开(公告)号:US20090058972A1

    公开(公告)日:2009-03-05

    申请号:US12198590

    申请日:2008-08-26

    CPC classification number: B41J3/28 B41J3/4078 B41J11/06 Y10S428/914

    Abstract: A printing apparatus including a conveyer system configured to convey a pallet having a print substrate thereon, anteroposterior moving mechanisms, fitting members disposed on the moving mechanisms, a guide bar member that extends in a lateral direction mounted on the fitting members, and a head device that is movably disposed along the guide bar member and has a plurality of inkjet nozzles. The printing apparatus is adapted to conduct printing by ejecting ink droplets from the inkjet nozzles to the print substrate on the pallet which is secured above an upper conveying passage and which is conveyed by the conveyer system while moving the head device.

    Abstract translation: 一种打印装置,包括:输送机系统,被配置为输送其上具有打印基板的托盘;前后移动机构;设置在所述移动机构上的装配构件;沿着安装在所述装配构件上的横向方向延伸的导杆构件;以及头装置 其沿着导杆构件可移动地设置并且具有多个喷墨喷嘴。 打印装置适于通过将墨滴从喷墨喷嘴喷射到固定在上输送通道上方的托盘上的打印基板,并且在移动头装置的同时由输送系统输送。

    Method of assisting selection of action and program product and game system using same
    4.
    发明授权
    Method of assisting selection of action and program product and game system using same 有权
    辅助选择动作的方法和使用该程序的产品和游戏系统

    公开(公告)号:US06533663B1

    公开(公告)日:2003-03-18

    申请号:US09580570

    申请日:2000-05-30

    Abstract: A player is assisted in selecting an action to be executed by a character on a screen by displaying multiple options, associated with corresponding actions, on the screen. A graphic, in virtual three dimensions, is displayed on the screen to visually depict a preview of a range of effect of an action corresponding to an option selected by an operational input by the player. The position of the graphic may be based on the position of the character at the time the option is selected. The range of effect may be switched to preview another action when the player switches the selected option. The options may be represented by icons and grouped according to the types of corresponding actions.

    Abstract translation: 通过在屏幕上显示与相应动作相关联的多个选项,协助玩家选择由屏幕上的角色执行的动作。 虚拟三维图形被显示在屏幕上,以可视地描绘与由玩家的操作输入选择的选项对应的动作的效果范围的预览。 图形的位置可以基于选择选项时字符的位置。 当播放器切换所选择的选项时,可以切换效果范围以预览另一动作。 选项可以由图标表示,并根据相应动作的类型进行分组。

    Member for office machines
    5.
    发明授权
    Member for office machines 有权
    办公机器会员

    公开(公告)号:US06273415B1

    公开(公告)日:2001-08-14

    申请号:US09473945

    申请日:1999-12-29

    Abstract: There is disclosed a member for office machines which comprises a core body and an annular elastic body installed on the peripheral surface thereof, wherein the expansion rate of the annular elastic body E(%) falls within the range of 5 to 30%, when expressed by the formula E(%)={(d1−d2)/d2}×100 wherein d1 in mm is the diameter of the core body, or a longest value in the cross-section of the core body in the shape of a roller or odd-shape; and d2 in mm is the inside diameter in mm of the annular elastic body before being installed on the peripheral surface of the core body. The member for office machines enables stable and steady paper sheet feeding, when used as a paper feeding member in electrophotographic equipment and electrostatic recording equipment, and equipment having a variety of paper feeding mechanisms such as ink-jet printers, automatic teller machines (ATM), money exchange machines, counting machines, automatic vending machines and cash dispensers (CD).

    Abstract translation: 公开了一种用于办公机器的构件,其包括安装在其外周表面上的芯体和环形弹性体,其中当表达时,环形弹性体E(%)的膨胀率落在5至30%的范围内 通过角质层d1以mm为单位,是芯体的直径,或芯体的横截面中的最长值为辊状或奇数形状; d2为mm,是安装在芯体的周面上之前的环状弹性体的内径(mm)。 用于办公机器的构件使得当用作电子照相设备和静电记录设备中的给纸构件时使用稳定且稳定的纸张馈送,以及具有各种送纸机构的设备,例如喷墨打印机,自动柜员机(ATM) 货币兑换机,点钞机,自动售货机和自动提款机(CD)。

    Printing apparatus
    7.
    发明授权
    Printing apparatus 有权
    印刷装置

    公开(公告)号:US08205736B2

    公开(公告)日:2012-06-26

    申请号:US12198563

    申请日:2008-08-26

    CPC classification number: B41F17/005

    Abstract: A printing apparatus including a pallet configured to receive a print substrate, a conveyer mechanism configured to convey the pallet, and a working device configured to conduct a processing operation for printing on the print substrate on the pallet. The printing apparatus further includes a locating mechanism configured to stop the pallet at a first holding position and a first holding mechanism configured to hold the pallet, stopped at the first holding position by the first locating mechanism, to be spaced apart from the conveying mechanism. After the pallet being conveyed by the conveying mechanism is stopped by the first locating mechanism, the pallet is held to be spaced apart from the conveying mechanism by the first holding mechanism and the processing operation is conducted by the working device relative to the print substrate on the pallet thus held.

    Abstract translation: 一种打印装置,包括构造成接收打印基板的托盘,构造成输送托盘的输送机构和被配置为进行用于在托盘上的打印基板上进行打印的处理操作的工作装置。 打印装置还包括定位机构,该定位机构构造成在第一保持位置处停止托盘;以及第一保持机构,该第一保持机构构造成用于保持通过第一定位机构停在第一保持位置处的托盘与输送机构间隔开。 在由输送机构输送的托盘被第一定位机构挡住之后,托盘通过第一保持机构与输送机构保持间隔开,并且处理操作由加工装置相对于打印基板进行 这样搁置的托盘。

    CARRIER TAPE, ELECTRONIC-COMPONENT ACCOMMODATING MEMBER AND METHOD OF TRANSPORTING ELECTRONIC COMPONENT
    8.
    发明申请
    CARRIER TAPE, ELECTRONIC-COMPONENT ACCOMMODATING MEMBER AND METHOD OF TRANSPORTING ELECTRONIC COMPONENT 有权
    载体带,电子部件容纳部件和运输电子部件的方法

    公开(公告)号:US20080202981A1

    公开(公告)日:2008-08-28

    申请号:US12036742

    申请日:2008-02-25

    CPC classification number: H05K13/0084

    Abstract: The invention provides carrier tapes in which, when the carrier tapes are wound up, regardless of the positions of accommodating portions of the upper and lower carrier tapes that overlap each other, electronic components accommodated in the accommodating portions can be reliably secured, so that the electronic components can be prevented from becoming dislodged from the accommodating portions; and electronic-component accommodating members including the carrier tapes.In each carrier tape having the plurality of accommodating portions that accommodate the electronic components and that are formed in a longitudinal direction, a plurality of protrusions are disposed at the bottom surfaces of the accommodating portions, and surfaces of interval portions provided between the accommodating portions that are adjacent to each other are formed lower than surfaces of guides of the carrier tapes.

    Abstract translation: 本发明提供了一种载带,其中当载带缠绕时,不管彼此重叠的上和下载带的容纳部分的位置如何,可以可靠地确保容纳在容纳部分中的电子部件, 可以防止电子部件从容纳部移除; 以及包括载带的电子部件容纳部件。 在具有容纳电子部件并且沿纵向形成的多个容纳部的每个载带中,在容纳部的底面设置有多个突起,在容纳部之间设置间隔部的表面, 彼此相邻形成为比载带的引导件的表面低。

    Electronic device receiving apparatus and method of loading/unloading an electronic device at electronic device receiving apparatus
    9.
    发明申请
    Electronic device receiving apparatus and method of loading/unloading an electronic device at electronic device receiving apparatus 审中-公开
    电子设备接收设备和在电子设备接收设备处加载/卸载电子设备的方法

    公开(公告)号:US20070146926A1

    公开(公告)日:2007-06-28

    申请号:US11361059

    申请日:2006-02-24

    CPC classification number: B65B15/04 H05K13/0419

    Abstract: An electronic device receiving apparatus having a sealed structure, includes a tape whereby an electronic device is received in the electronic device receiving apparatus. The tape elastically holds the electronic device and runs inside of the electronic device receiving apparatus. An opening part for loading/unloading and a tape extending mechanism are provided inside of the electronic device receiving apparatus. The opening part for loading/unloading is provided above the tape so that the electronic device is loaded onto and unloaded from the tape. The opening part for loading/unloading has an opening part configured to open the electronic device receiving apparatus. The tape extending part extends the tape in a direction substantially perpendicular to a running direction of the tape.

    Abstract translation: 一种具有密封结构的电子设备接收设备,包括一个电子设备接收在电子设备接收设备中的带子。 胶带弹性地保持电子装置并在电子装置接收装置的内部运行。 在电子设备接收设备内部设置有用于装载/卸载的开口部分和带延伸机构。 用于装载/卸载的开口部分设置在带的上方,使得电子装置被装载到带上并从带上卸载。 用于装载/卸载的开启部分具有打开电子装置接收装置的开口部分。 带延伸部分沿着与带的运行方向基本垂直的方向延伸带。

    Tray for semiconductor device and semiconductor device
    10.
    发明授权
    Tray for semiconductor device and semiconductor device 有权
    半导体器件和半导体器件托盘

    公开(公告)号:US07163104B2

    公开(公告)日:2007-01-16

    申请号:US10958393

    申请日:2004-10-06

    Abstract: A tray for a semiconductor device and the semiconductor device are disclosed in which the resist of the semiconductor is not easily separated from the substrate. A tray for semiconductor device has a support section formed as a pocket for carrying the semiconductor device, a pair of first protrusions formed on the opposite sides of the support section, and a pair of second protrusions formed on the opposite sides of the tray on the surface side reverse to the surface side where the support section are provided. The second protrusions are arranged in spaced relation to and in the same direction as the first protrusions. The interval between the first protrusions is larger than the interval between the second protrusions, so that in the case where the tray receives a shock, the semiconductor device comes into contact with the second protrusions earlier than with the first protrusions, thereby making it difficult for the resist of the semiconductor device to come off.

    Abstract translation: 公开了一种用于半导体器件的托盘和半导体器件,其中半导体的抗蚀剂不容易与基底分离。 用于半导体器件的托盘具有形成为用于承载半导体器件的袋的支撑部,形成在支撑部的相对侧上的一对第一突起和形成在托盘的相对侧上的一对第二突起 表面侧与设置有支撑部的表面侧相反。 第二突起以与第一突起间隔开并且与第一突起相同的方向布置。 第一突起之间的间隔大于第二突起之间的间隔,使得在托盘受到冲击的情况下,半导体器件比第一突起更早地与第二突起接触,从而难以 半导体器件的抗蚀剂脱落。

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