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公开(公告)号：US20200093505A1
公开(公告)日：2020-03-26
申请号：US16683071
申请日：2019-11-13
申请人： Yegor D. SINELNIKOV , Zoar Jacob ENGELMAN , Mark GELFAND , Martin M. GRASSE , Timothy A. KOSS , Michael Brick MARKHAM , Kenneth M. MARTIN , Veijo T. SUORSA , Miriam H. TAIMISTO , Xian WEI , Brice Arnault DE LA MENARDIERE , Clayton Miles BALDWIN , Jason Michael MILLER
发明人： Yegor D. SINELNIKOV , Zoar Jacob ENGELMAN , Mark GELFAND , Martin M. GRASSE , Timothy A. KOSS , Michael Brick MARKHAM , Kenneth M. MARTIN , Veijo T. SUORSA , Miriam H. TAIMISTO , Xian WEI , Brice Arnault DE LA MENARDIERE , Clayton Miles BALDWIN , Jason Michael MILLER
IPC分类号： A61B17/3207 , A61B8/12 , A61B8/00 , A61B8/08 , A61B17/32 , A61B17/22 , A61N7/02 , A61B18/14 , A61M25/09
摘要： Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation. The methods may be performed using an ultrasound ablation catheter. The methods may also include imaging using at least one ultrasound imaging catheter.
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公开(公告)号：US20130324989A1
公开(公告)日：2013-12-05
申请号：US13908995
申请日：2013-06-03
申请人： Mark Leung , Brett Schleicher , Charles Lennox , Ary Chernomorsky , Zoar Jacob Engelman , Marat Fudim , Martin M. Grasse , Mark Gelfand , Howard Levin
发明人： Mark Leung , Brett Schleicher , Charles Lennox , Ary Chernomorsky , Zoar Jacob Engelman , Marat Fudim , Martin M. Grasse , Mark Gelfand , Howard Levin
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B8/0841 , A61B8/0891 , A61B8/12 , A61B8/145 , A61B8/4227 , A61B8/488 , A61B18/1477 , A61B18/22 , A61B90/11 , A61B2018/00041 , A61B2018/00404 , A61B2018/00791 , A61B2018/0212 , A61B2018/0293 , A61B2090/376 , A61B2090/3762 , A61B2090/378 , A61N7/022 , A61N2007/0026 , F04C2270/0421
摘要： Methods and percutaneous devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via percutaneous carotid body ablation.
摘要翻译： 用于评估和治疗患有交感神经介导的疾病的患者的方法和经皮装置，通过经由经皮颈动脉体消融将化学传感器输入减少到神经系统，涉及增加的外周化学反应和增强的交感神经紧张。
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公开(公告)号：US11413090B2
公开(公告)日：2022-08-16
申请号：US17152665
申请日：2021-01-19
申请人： Pajhand Iranitalab , Casey Andrew Miller , Thomas Ryan McGrath , Manuel Arzadon Javier, Jr. , Anisha Bapna , Zoar Jacob Engelman , Howard Levin , Nicholas C. VanDillen , Anne Marie Ahonen
发明人： Pajhand Iranitalab , Casey Andrew Miller , Thomas Ryan McGrath , Manuel Arzadon Javier, Jr. , Anisha Bapna , Zoar Jacob Engelman , Howard Levin , Nicholas C. VanDillen , Anne Marie Ahonen
摘要： Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.
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4.发明申请CAROTID BODY ABLATION WITH A TRANSVENOUS ULTRASOUND IMAGING AND ABLATION CATHETER 审中-公开具有超声波超声成像和吸收导管的CAROTID身体吸收公开(公告)号：US20160374710A1
公开(公告)日：2016-12-29
申请号：US15263174
申请日：2016-09-12
申请人： Yegor D. SINELNIKOV , Zoar Jacob ENGELMAN , Mark GELFAND , Martin M. GRASSE , Timothy A. KOSS , Michael Brick MARKHAM , Kenneth M. MARTIN , Veijo T. SUORSA , Miriam H. TAIMISTO , Xian WEI , Brice Arnault DE LA MENARDIERE , Clayton Miles BALDWIN , Jason MILLER
发明人： Yegor D. SINELNIKOV , Zoar Jacob ENGELMAN , Mark GELFAND , Martin M. GRASSE , Timothy A. KOSS , Michael Brick MARKHAM , Kenneth M. MARTIN , Veijo T. SUORSA , Miriam H. TAIMISTO , Xian WEI , Brice Arnault DE LA MENARDIERE , Clayton Miles BALDWIN , Jason MILLER
IPC分类号： A61B17/32 , A61B17/3207 , A61B8/08 , A61B8/12 , A61B8/00
CPC分类号： A61B17/3207 , A61B8/0891 , A61B8/12 , A61B8/445 , A61B8/481 , A61B8/54 , A61B17/2202 , A61B17/320068 , A61B17/3478 , A61B18/1492 , A61B18/24 , A61B2017/00106 , A61B2017/00225 , A61B2017/0023 , A61B2017/00256 , A61B2017/00296 , A61B2017/003 , A61B2017/22024 , A61B2017/22028 , A61B2017/22058 , A61B2017/22062 , A61B2017/22069 , A61B2017/320044 , A61B2017/320069 , A61B2017/320071 , A61B2017/320084 , A61B2018/00023 , A61B2018/00404 , A61B2018/00577 , A61B2018/1425 , A61B2018/1475 , A61B2034/2063 , A61B2034/2065 , A61B2090/3782 , A61B2090/3784 , A61B2217/007 , A61M25/09 , A61N7/022 , A61N2007/0052
摘要： Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation. The methods may be performed using an ultrasound ablation catheter. The methods may also include imaging using at least one ultrasound imaging catheter.
摘要翻译： 用于评估和治疗患有交感神经介导的疾病的患者的方法和装置，通过减少化学传感器通过颈动脉体消融对输入神经系统的输入，涉及增加的外周化学反应和增强的交感神经紧张。 该方法可以使用超声消融导管进行。 所述方法还可以包括使用至少一个超声成像导管的成像。
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5.发明申请CAROTID BODY ABLATION WITH A TRANSVENOUS ULTRASOUND IMAGING AND ABLATION CATHETER 有权具有超声波超声成像和吸收导管的CAROTID身体吸收公开(公告)号：US20150257779A1
公开(公告)日：2015-09-17
申请号：US14656635
申请日：2015-03-12
申请人： Yegor D. SINELNIKOV , Zoar Jacob ENGELMAN , Mark GELFAND , Martin M. GRASSE , Timothy A. KOSS , Michael Brick MARKHAM , Kenneth M. MARTIN , Veijo T. SUORSA , Miriam H. TAIMISTO , Xian WEI
发明人： Yegor D. SINELNIKOV , Zoar Jacob ENGELMAN , Mark GELFAND , Martin M. GRASSE , Timothy A. KOSS , Michael Brick MARKHAM , Kenneth M. MARTIN , Veijo T. SUORSA , Miriam H. TAIMISTO , Xian WEI
CPC分类号： A61B8/12 , A61B8/0841 , A61B8/0891 , A61B8/445 , A61B8/4477 , A61B8/481 , A61B8/488 , A61B2018/00023 , A61B2018/00029 , A61B2090/0472 , A61B2090/378 , A61B2090/3782 , A61B2090/3784 , A61B2090/3925 , A61B2090/3983 , A61N7/022
摘要： Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.
摘要翻译： 用于评估和治疗患有交感神经介导的疾病的患者的方法和装置，通过减少化学传感器通过颈动脉体消融对输入神经系统的输入，涉及增加的外周化学反应和增强的交感神经紧张。
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6.发明申请公开(公告)号：US20220257315A1
公开(公告)日：2022-08-18
申请号：US17452305
申请日：2021-10-26
IPC分类号： A61B18/14
摘要： Apparatuses and methods for treating a heart failure patient by ablating a nerve of the thoracic splanchnic sympathetic nervous system to increase venous capacitance and reduce pulmonary blood pressure. A method comprising: inserting a catheter into a vein adjacent the nerve, applying stimulation energy and observing hemodynamic effects, applying ablation energy and observing hemodynamic effects, applying simulation energy after the ablation and observing hemodynamic effects and monitoring for presence of the lung in the ablation zone. An alternative method comprising: inserting a catheter into a vein adjacent the nerve, detecting that lung tissue is a safe distance from an ablation zone, and delivering ablation energy to the target nerve when lung tissue is a safe distance from the ablation zone.
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公开(公告)号：US20210220043A1
公开(公告)日：2021-07-22
申请号：US17152665
申请日：2021-01-19
申请人： Pajhand IRANITALAB , Casey Andrew MILLER , Thomas Ryan McGRATH , Manuel Arzadon JAVIER, JR. , Anisha BAPNA , Zoar Jacob ENGELMAN , Howard LEVIN , Nicholas C. VanDILLEN , Anne Marie AHONEN
发明人： Pajhand IRANITALAB , Casey Andrew MILLER , Thomas Ryan McGRATH , Manuel Arzadon JAVIER, JR. , Anisha BAPNA , Zoar Jacob ENGELMAN , Howard LEVIN , Nicholas C. VanDILLEN , Anne Marie AHONEN
IPC分类号： A61B18/14
摘要： Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.
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公开(公告)号：US20200179047A1
公开(公告)日：2020-06-11
申请号：US16793698
申请日：2020-02-18
申请人： Dorin PANESCU , Andrew WU , Zoar Jacob ENGELMAN , Mark GELFAND , Mark S. LEUNG , Howard LEVIN
发明人： Dorin PANESCU , Andrew WU , Zoar Jacob ENGELMAN , Mark GELFAND , Mark S. LEUNG , Howard LEVIN
IPC分类号： A61B18/14
摘要： Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are method of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.
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公开(公告)号：US20190183569A1
公开(公告)日：2019-06-20
申请号：US16222823
申请日：2018-12-17
申请人： Dorin PANESCU , Andrew WU , Zoar Jacob ENGELMAN , Mark GELFAND , Mark S. LEUNG , Howard LEVIN
发明人： Dorin PANESCU , Andrew WU , Zoar Jacob ENGELMAN , Mark GELFAND , Mark S. LEUNG , Howard LEVIN
IPC分类号： A61B18/14
摘要： Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are method of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.
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10.发明申请CAROTID SEPTUM ABLATION WITH ULTRASOUND IMAGING AND ABLATION CATHETERS 审中-公开超声波成像和超声波吸收的CAROTID SEPTUM吸收公开(公告)号：US20160338724A1
公开(公告)日：2016-11-24
申请号：US15069531
申请日：2016-03-14
申请人： Yegor D. SINELNIKOV , Zoar Jacob ENGELMAN , Mark GELFAND , Martin M. GRASSE , Timothy A. KOSS , Michael Brick MARKHAM , Kenneth M. MARTIN , Veijo T. SUORSA , Miriam H. TAIMISTO , Xian WEI
发明人： Yegor D. SINELNIKOV , Zoar Jacob ENGELMAN , Mark GELFAND , Martin M. GRASSE , Timothy A. KOSS , Michael Brick MARKHAM , Kenneth M. MARTIN , Veijo T. SUORSA , Miriam H. TAIMISTO , Xian WEI
CPC分类号： A61M25/09 , A61B8/0891 , A61B8/12 , A61B8/445 , A61B17/2202 , A61B18/1492 , A61B18/24 , A61B2017/00106 , A61B2017/00256 , A61B2017/003 , A61B2017/22024 , A61B2017/22028 , A61B2017/22058 , A61B2017/22062 , A61B2017/22069 , A61B2017/320044 , A61B2017/320069 , A61B2017/320071 , A61B2018/00023 , A61B2018/00404 , A61B2018/00577 , A61B2018/1425 , A61B2018/1475 , A61B2034/2063 , A61B2034/2065 , A61B2090/3782 , A61B2090/3784 , A61N7/022
摘要： Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.
摘要翻译： 用于评估和治疗患有交感神经介导的疾病的患者的方法和装置，通过减少化学传感器通过颈动脉体消融对输入神经系统的输入，涉及增加的外周化学反应和增强的交感神经紧张。
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