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公开(公告)号：US09421223B2
公开(公告)日：2016-08-23
申请号：US14622131
申请日：2015-02-13
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Thierry Glauser , Stephen D. Pacetti , Paul M. Consigny
CPC classification number: A61K33/00 , A61K45/06 , A61L29/16 , A61L31/08 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/114 , A61L2300/606
Abstract: Medical devices having a catalyst capable of catalyzing the generation of nitric oxide in vivo and methods of treating a vascular condition using the devices are provided.
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2.发明授权Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same 有权用于包含乳酸聚合物的可植入装置的涂层及其制造方法公开(公告)号：US09408949B2
公开(公告)日：2016-08-09
申请号：US14476623
申请日：2014-09-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F. A. Hossainy , Yiwen Tang , Eugene T. Michal , Thierry Glauser , Stephen D. Pacetti , Jessica DesNoyer
CPC classification number: A61L31/10 , A61F2250/0067 , A61L27/28 , A61L27/34 , A61L29/08 , A61L29/085 , A61L31/08 , A61L31/148 , A61L31/16 , A61L2420/00 , A61L2420/02 , A61L2420/06 , C08L67/04
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
Abstract translation: 公开了用于可植入医疗装置的涂层及其制造方法，所述涂层包含乳酸聚合物。
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3.发明申请MODIFYING POLYMER PROPERTIES WITH PENETRANTS IN THE FABRICATION OF BIORESORBABLE SCAFFOLDS 审中-公开在生物降解药物制剂中改性聚苯乙烯特性公开(公告)号：US20160175493A1
公开(公告)日：2016-06-23
申请号：US14931041
申请日：2015-11-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , John Stankus , Michael N. Ngo , Wen Chung Tsai , Thierry Glauser
CPC classification number: A61L31/148 , A61L31/06 , A61L31/08 , A61L31/141 , A61L2420/02 , B05D5/00 , C08L67/04
Abstract: Methods of fabricating a bioresorbable polymer scaffold are disclosed including a step of inducing crystallization in a bioresorbable polymer construct through exposure to a liquid penetrant.
Abstract translation: 公开了制备生物可再吸收的聚合物支架的方法，包括通过暴露于液体渗透剂在生物可再吸收的聚合物构造体中诱导结晶的步骤。
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公开(公告)号：US09101697B2
公开(公告)日：2015-08-11
申请号：US14251489
申请日：2014-04-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Faiyaz Ahmed Hossainy , Eugene Michal , Thierry Glauser , Connie Kwok , Stephen Dirk Pacetti
IPC: A61K31/44 , A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16
CPC classification number: A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16 , A61K2300/00 , C08L5/08 , C08L5/10
Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
Abstract translation: 提供了用于涂覆可植入装置的透明质酸（HA）缀合物或交联的HA组合物。 可植入装置可用于治疗动脉粥样硬化，血栓形成，再狭窄，高胆固醇，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍，胆管 梗阻，输尿管阻塞，肿瘤阻塞及其组合。
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公开(公告)号：US20140221418A1
公开(公告)日：2014-08-07
申请号：US14251489
申请日：2014-04-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Faiyaz Ahmed Hossainy , Eugene Michal , Thierry Glauser , Connie Kwok , Stephen Dirk Pacetti
CPC classification number: A61L31/10 , A61K31/727 , A61K31/728 , A61K31/785 , A61L31/16 , A61K2300/00 , C08L5/08 , C08L5/10
Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
Abstract translation: 提供了用于涂覆可植入装置的透明质酸（HA）缀合物或交联的HA组合物。 可植入装置可用于治疗动脉粥样硬化，血栓形成，再狭窄，高胆固醇，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍，胆管 梗阻，输尿管阻塞，肿瘤阻塞及其组合。
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Patent Agency Ranking
6.发明申请COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLY(HYDROXY-ALKANOATES) AND DIACID LINKAGES 审中-公开用于包含聚（羟基 - 烷基）酸酯和双向连接的可植入装置的涂料公开(公告)号：US20140100302A1
公开(公告)日：2014-04-10
申请号：US14082922
申请日：2013-11-18
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Stephen Dirk Pacetti , Thierry Glauser
IPC: A61L31/10
CPC classification number: A61L31/10 , A61L27/34 , C08G63/66 , C09D167/00
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings including block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.
Abstract translation: 公开了用于可植入医疗装置的涂层及其制造方法，所述涂层包括包含至少一种聚（羟基酸）或聚（羟基 - 链烷酸酯）嵌段的嵌段聚合物，至少一个生物相容性聚合物的嵌段和至少 一种类型的连接部分。
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公开(公告)号：US20140081417A1
公开(公告)日：2014-03-20
申请号：US14084427
申请日：2013-11-19
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , David C. Gale , Bin Huang , Mikael O. Trollsas , Thierry Glauser , Florian Ludwig
IPC: A61L27/14
Abstract: Stent scaffolds comprising branched biocompatible polymers are disclosed.
Abstract translation: 公开了包含支链生物相容性聚合物的支架支架。
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公开(公告)号：US20130187313A1
公开(公告)日：2013-07-25
申请号：US13734879
申请日：2013-01-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Thierry Glauser , Vincent Gueriguian , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth
CPC classification number: B29D22/00 , A61F2/91 , B29C49/0005 , B29C49/02 , B29C49/04 , B29C49/08 , B29C49/78 , B29C55/26 , B29C2793/009 , B29K2995/004 , B29K2995/0041 , B29K2995/0046 , B29K2995/0056 , B29K2995/006 , B29K2995/0077 , B29K2995/0089 , B29L2031/7542
Abstract: Methods to expand polymer tubing with desirable or optimum morphology and mechanical properties for stem manufacture and fabrication of a stent therefrom are disclosed.
Abstract translation: 公开了扩展聚合物管的方法，其具有用于茎的制造和制造支架的所需或最佳形态和机械性能。
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公开(公告)号：US10213949B2
公开(公告)日：2019-02-26
申请号：US14852135
申请日：2015-09-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Bethany Steichen , Stephen Pacetti , Manish Gada , Thierry Glauser , Lothar Kleiner , Yunbing Wang , James Oberhauser , Ni Ding
Abstract: Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
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公开(公告)号：US09931431B2
公开(公告)日：2018-04-03
申请号：US13941374
申请日：2013-07-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , David C. Gale , Bin Huang , Mikael O. Trollsas , Thierry Glauser , Florian Ludwig
Abstract: Implantable medical devices fabricated from branched polymers are disclosed.
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