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    ANTI-BACTERIAL PATTERNED SURFACES AND METHODS OF MAKING THE SAME
    1.
    发明申请
    ANTI-BACTERIAL PATTERNED SURFACES AND METHODS OF MAKING THE SAME 审中-公开

    公开(公告)号：US20190037841A1

    公开(公告)日：2019-02-07

    申请号：US16077440

    申请日：2017-02-13

    申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    发明人： Yugen ZHANG ,  Guangshun YI

    IPC分类号： A01N25/34 ,  C23C22/63 ,  A01N59/20 ,  A01N59/08

    摘要： The present invention relates to a substrate comprising a plurality of integrally formed surface features, said surface features being micro-sized and/or nano-sized, said surface features comprising at least one pointed terminus. As a result of this unique surface, said substrate exhibits a biocidal activity because the terminal ends of said surface feature pierce through cell membrane of any microbial cell that comes into contact with the substrate, thereby causing cell deformation and lysis. The present invention also relates to a method producing said substrate. By a simple treatment of copper or zinc foil with a reagent solution comprising an alkali and an oxidizing agent, Cu(OH)2 nanotube arrays, CuO nano-blades and ZnO nano-needles are prepared. These surfaces are proven to be very effective in killing bacterial (such as E. coli) via a physical interaction.

    ANTIMICROBIAL COATINGS
    2.
    发明申请
    ANTIMICROBIAL COATINGS 审中-公开

    公开(公告)号：US20180320000A1

    公开(公告)日：2018-11-08

    申请号：US15769709

    申请日：2016-10-19

    申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    发明人： Yugen ZHANG ,  Yuan YUAN

    IPC分类号： C09D5/14 ,  A61K31/4164 ,  A61K47/02 ,  C07F3/06

    摘要： A coating comprising a metal-organic framework, wherein the metal-organic framework having a zeolitic structure comprising at least one multivalent metal species and at least one organic ligand (such as zeolitic imidazolate framework (ZIF)). Said coating has a topography comprising an array of projections, and each projection having at least one tapered distal end. There is also provided a method of coating substrates with the disclosed coating and use of said coating as a disinfectant, an antiseptic, or an antibiotic. Such use is possible because the tapered distal end of the disclosed zeolitic structure exerting higher pressure on any microbial cell that comes into contact with the disclosed coating, thereby piercing through the cell membrane more easily, causing cell deformation and lysis.

    CONVERSION AND PURIFICATION OF BIOMASS
    3.
    发明申请
    CONVERSION AND PURIFICATION OF BIOMASS 审中-公开
    生物质的转化和纯化

    公开(公告)号：US20160207899A1

    公开(公告)日：2016-07-21

    申请号：US15023668

    申请日：2014-09-17

    申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    发明人： Guangshun YI ,  Yugen ZHANG

    IPC分类号： C07D307/68 ,  B01J23/00 ,  B01J35/00 ,  B01J23/52

    CPC分类号： C07D307/68 ,  B01J23/007 ,  B01J23/52 ,  B01J23/66 ,  B01J35/0013 ,  B01J37/035 ,  C07D307/48

    摘要： The present invention relates to a method for synthesizing an optionally substituted furoic acid by dehydrating a biomass and oxidizing the optionally substituted furan derived from the dehydration reaction. Water extraction has been incorporated as a step between the dehydration and the oxidation in order to purify the intermediate optionally substituted furan before having it oxidized. Prior to this water extraction, the organic solvent used for dehydration may be separated by evaporation. The provision of the water extraction allows impurities to be separated from the intermediate optionally substituted furan.

    摘要翻译： 本发明涉及通过使生物质脱水并氧化来自脱水反应的任选取代的呋喃来合成任选取代的糠酸的方法。 水提取作为脱水和氧化之间的步骤被并入，以在中和任选取代的呋喃被氧化之前进行纯化。 在这种水提取之前，用于脱水的有机溶剂可以通过蒸发分离。 提供水提取允许杂质与中间任选取代的呋喃分离。

    TRIPHASIC SYSTEM FOR DIRECT CONVERSION OF SUGARS TO FURANDICARBOXYLIC ACID
    4.
    发明申请
    TRIPHASIC SYSTEM FOR DIRECT CONVERSION OF SUGARS TO FURANDICARBOXYLIC ACID 审中-公开

    公开(公告)号：US20170298039A1

    公开(公告)日：2017-10-19

    申请号：US15516018

    申请日：2015-09-29

    申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    发明人： Guangshun YI ,  Yugen ZHANG

    IPC分类号： C07D307/68 ,  B01J19/24

    CPC分类号： C07D307/68 ,  B01J19/245

    摘要： There is provided a one-pot process for the conversion of sugars to furancarboxylic acids, such as 2,5-furancarboxylic acid (FDCA), in a triphasic system (e.g. water or tetraethylammonium bromide (TEAB)—methyl isobutyl ketone (MIBK)—water). In this reaction setup, sugars are first converted to 5-hydroxymethylfurfural (HMF) in a first phase. Then HMF is then extracted into a second phase and transferred to a third phase of water. In the third phase HMF is converted to the furancarboxylic acid. The overall acid yields obtainable are between about 78% and 50% for conversion from fructose and glucose, respectively. The invention further relates to an apparatus for the triphasic reaction. The apparatus comprises two chambers which allow for the chemically separated reaction of the sugars and the intermediate of the sugars to form the final product in one process. The process according to the invention may be useful for industrial fabrication.