公开(公告)号：US09550878B2

公开(公告)日：2017-01-24

申请号：US14418034

申请日：2013-08-07

Applicant: AMORPHICAL LTD.

Inventor： Oren Meiron ,  Binyamin Ashkenazi

IPC: C01F11/18 ,  C08K3/26 ,  C09C1/02 ,  B82Y30/00 ,  A61K33/10 ,  C08K5/092 ,  C08K5/17 ,  C08K5/521 ,  C08K5/5399 ,  C08L5/00 ,  D21H17/00

CPC classification number: C09C1/021 ,  A23L33/16 ,  A23V2002/00 ,  A61K33/10 ,  B82Y30/00 ,  C01F11/182 ,  C01F11/183 ,  C01F11/185 ,  C01P2002/02 ,  C01P2002/72 ,  C01P2002/82 ,  C01P2004/30 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/22 ,  C01P2006/36 ,  C01P2006/82 ,  C08K3/26 ,  C08K5/092 ,  C08K5/175 ,  C08K5/521 ,  C08K5/5399 ,  C08K2003/265 ,  C08L5/00 ,  C09D17/004 ,  C09J11/04 ,  D21H17/74

Abstract: Provided is a method for preparing a stable amorphous calcium carbonate (ACC), which can be obtained either in suspension or as a powder. The method comprises stepwise combination of a soluble calcium salt, a soluble carbonate, a first and second stabilizer, and a water miscible organic solvent as described herein. The present invention further relates to stable ACC suspensions and dry powders produced by the method of the present invention.

Abstract translation: 提供一种制备稳定的无定形碳酸钙（ACC）的方法，其可以以悬浮液或粉末形式获得。 该方法包括如本文所述的可溶性钙盐，可溶性碳酸盐，第一和第二稳定剂以及水混溶性有机溶剂的逐步组合。 本发明还涉及通过本发明的方法制备的稳定的ACC悬浮液和干粉。

公开(公告)号：US10125262B2

公开(公告)日：2018-11-13

申请号：US15370623

申请日：2016-12-06

Applicant: AMORPHICAL LTD.

Inventor： Oren Meiron ,  Binyamin Ashkenazi

IPC: C01F11/18 ,  C09C1/02 ,  B82Y30/00 ,  A61K33/10 ,  C08K3/26 ,  C08K5/092 ,  C08K5/17 ,  C08K5/521 ,  C08K5/5399 ,  C08L5/00 ,  D21H17/00 ,  A23L33/16 ,  C09D17/00 ,  C09J11/04

Abstract: Provided is a method for preparing a stable amorphous calcium carbonate (ACC), which can be obtained either in suspension or as a powder. The method comprises stepwise combination of a soluble calcium salt, a soluble carbonate, a first and second stabilizer, and a water miscible organic solvent as described herein. The present invention further relates to stable ACC suspensions and dry powders produced by the method of the present invention.

公开(公告)号：US20170081520A1

公开(公告)日：2017-03-23

申请号：US15370623

申请日：2016-12-06

Applicant: AMORPHICAL LTD.

Inventor： Oren Meiron ,  Binyamin Ashkenazi

IPC: C09C1/02 ,  C09D17/00 ,  A61K33/10 ,  C08K3/26 ,  A23L33/16 ,  C08K5/092 ,  C08K5/17 ,  C09J11/04 ,  D21H17/00 ,  C01F11/18 ,  C08K5/521

CPC classification number: C09C1/021 ,  A23L33/16 ,  A23V2002/00 ,  A61K33/10 ,  B82Y30/00 ,  C01F11/182 ,  C01F11/183 ,  C01F11/185 ,  C01P2002/02 ,  C01P2002/72 ,  C01P2002/82 ,  C01P2004/30 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/22 ,  C01P2006/36 ,  C01P2006/82 ,  C08K3/26 ,  C08K5/092 ,  C08K5/175 ,  C08K5/521 ,  C08K5/5399 ,  C08K2003/265 ,  C08L5/00 ,  C09D17/004 ,  C09J11/04 ,  D21H17/74

Abstract: Provided is a method for preparing a stable amorphous calcium carbonate (ACC), which can be obtained either in suspension or as a powder. The method comprises stepwise combination of a soluble calcium salt, a soluble carbonate, a first and second stabilizer, and a water miscible organic solvent as described herein. The present invention further relates to stable ACC suspensions and dry powders produced by the method of the present invention.

公开(公告)号：US20150166762A1

公开(公告)日：2015-06-18

申请号：US14418034

申请日：2013-08-07

Applicant: AMORPHICAL LTD.

Inventor： Oren Meiron ,  Binyamin Ashkenazi

IPC: C08K3/26 ,  C08K5/521 ,  C08K5/092 ,  A23L1/304 ,  C08K5/17 ,  C08L5/00 ,  D21H17/00 ,  A61K33/10 ,  C08K5/5399

CPC classification number: C09C1/021 ,  A23L33/16 ,  A23V2002/00 ,  A61K33/10 ,  B82Y30/00 ,  C01F11/182 ,  C01F11/183 ,  C01F11/185 ,  C01P2002/02 ,  C01P2002/72 ,  C01P2002/82 ,  C01P2004/30 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/22 ,  C01P2006/36 ,  C01P2006/82 ,  C08K3/26 ,  C08K5/092 ,  C08K5/175 ,  C08K5/521 ,  C08K5/5399 ,  C08K2003/265 ,  C08L5/00 ,  C09D17/004 ,  C09J11/04 ,  D21H17/74

Abstract: Provided is a method for preparing a stable amorphous calcium carbonate (ACC), which can be obtained either in suspension or as a powder. The method comprises stepwise combination of a soluble calcium salt, a soluble carbonate, a first and second stabilizer, and a water miscible organic solvent as described herein. The present invention further relates to stable ACC suspensions and dry powders produced by the method of the present invention.

Abstract translation: 提供一种制备稳定的无定形碳酸钙（ACC）的方法，其可以以悬浮液或粉末形式获得。 该方法包括如本文所述的可溶性钙盐，可溶性碳酸盐，第一和第二稳定剂以及水混溶性有机溶剂的逐步组合。 本发明还涉及通过本发明的方法制备的稳定的ACC悬浮液和干粉。