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公开(公告)号:US10741034B2
公开(公告)日:2020-08-11
申请号:US14570242
申请日:2014-12-15
申请人: APDN (B.V.I.) Inc.
IPC分类号: C12Q1/68 , G08B15/02 , C12Q1/6876 , B05D1/00
摘要: A method of marking an inventory item includes providing an activatable smoke generator and a reservoir for holding a smoke fluid and adapted to provide a flow of smoke fluid to the generator. The reservoir contains a smoke fluid including a carrier nucleic acid having a uniquely identifiable sequence, and upon activation of the smoke generator, marker smoke is generated and targeted to flow over the inventory item. The method further includes activating the smoke generator to produce the marker smoke including the carrier nucleic acid so as to cause the marker smoke to flow over the inventory item and thereby to detectably mark the inventory item with carrier nucleic acid. The invention provides methods for stably binding and immobilizing deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. The alkaline conditions are produced by mixing the deoxyribonucleic acid with an alkaline solution having a pH of about 9.0 or higher, and contacting the deoxyribonucleic acid to the substrate. The immobilized DNA can be used as a taggant and can be used in combination with other detectable taggants, such as optical reporters.
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公开(公告)号:US09290819B2
公开(公告)日:2016-03-22
申请号:US14584309
申请日:2014-12-29
申请人: APDN (B.V.I.) Inc.
CPC分类号: C12Q1/6895 , C12Q2600/13 , C12Q2600/156
摘要: Methods for distinguishing between cotton cultivars of a specific species by analyzing a sample of mature cotton fibers from raw cotton materials or from textile goods are disclosed. DNA is extracted from the mature cotton fiber sample and subjected to PCR techniques which enable the identification of the cultivar of a particular cotton species utilized in the textile or cotton material of interest.
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公开(公告)号:US10745825B2
公开(公告)日:2020-08-18
申请号:US16028176
申请日:2018-07-05
申请人: APDN (B.V.I.) INC.
IPC分类号: B29C65/00 , B29C65/48 , B29C71/00 , B32B37/00 , B41M3/14 , G07D7/14 , C40B20/04 , G07D7/1205 , B42D25/00 , C09B11/22 , C09B11/24 , C09B69/10 , C09B11/08 , C12Q1/68 , C09B23/16 , C09B57/10 , G07D7/202 , C12Q1/6876
摘要: Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The encrypted marker may include a DNA taggant.
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公开(公告)号:US20180173810A1
公开(公告)日:2018-06-21
申请号:US15868510
申请日:2018-01-11
申请人: APDN (B.V.I.) INC.
发明人: Judith Murrah , Phidung H. Tran , Maciej B. Szczepanik , MingHwa Benjamin Liang , James A. Hayward
CPC分类号: G06F17/30876 , G06K7/0004 , G06K19/06037 , G06K19/0723
摘要: A system associated with authentication of an object related to a multi-mode marker using a processing device. The processing device performs operations that include detecting a signal associated with a multi-mode marker related with the object; assigning a digital code based on the detected signal associated with the multi-mode marker; and identifying the object based on the digital code related to authentication of the object. A corresponding method and computer-readable device are also disclosed.
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公开(公告)号:US09904734B2
公开(公告)日:2018-02-27
申请号:US15027454
申请日:2014-10-07
申请人: APDN (B.V.I.) INC.
发明人: Judith Murrah , Phidung H. Tran , Maciej B. Szczepanik , MingHwa Benjamin Liang , James A. Hayward
CPC分类号: G06F17/30876 , G06K7/0004 , G06K19/06037 , G06K19/0723
摘要: A multi-mode reader instrument capable of detecting and determining digital data from a signal from one or more markers, indicia or taggants on an object, the markers, indicia or taggants such as a bar code, a QR code, an RFID, an optical compound, a fluorescent compound, a phosphorescent compound, a DNA taggant, an upconverting phosphor (UCP), a chemical dye, a digitized image, a radioactive compound, an olfactory compound or a thermal attribute of the object is provided. Also, provided is a method and a system for identifying an object, the system includes: a multi-mode reader instrument for detecting data from a signal from one or more markers, indicia or taggants on an object and assignment of digital code for the marker and a database for securing and retrieving information relevant to the item.
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6.
公开(公告)号:US20170021611A1
公开(公告)日:2017-01-26
申请号:US15049170
申请日:2016-02-22
申请人: APDN (B.V.I.) Inc.
CPC分类号: B41F17/00 , B41M3/14 , B42D25/378 , B42D25/405 , C12Q1/68 , G07D7/14 , Y10T29/49826 , Y10T29/49885
摘要: The invention provides a method of marking an item with naturally-derived or synthetic non-natural polymeric marker molecules, such as a DNA or Peptide marker in conjunction with optional visible or rapid scan reporters for authenticating or tracking, in which the method includes providing an item for marking, and applying a medium including a DNA marker to the item. The invention further provides methods for stably binding and immobilizing activated deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. Also provided are methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. The invention also provides a method of marking an item with a DNA marker for authenticating or tracking, in which the method includes providing a medium including a DNA marker, and molding the medium including the DNA marker to provide all or part of the item. The DNA marker encodes information unique to the item and/or the model of the item as desired.
摘要翻译: 本发明提供了一种使用天然衍生或合成的非天然聚合物标记分子(例如DNA或肽标记)与用于鉴定或跟踪的可选的可见或快速扫描记录器一起标记物品的方法,其中所述方法包括提供 用于标记的项目,以及将包括DNA标记的培养基应用于该物品。 本发明还提供了将活化的脱氧核糖核酸稳定结合并固定在物体和底物上的方法。 该方法包括将脱氧核糖核酸暴露于碱性条件下,并使脱氧核糖核酸与对象或底物接触。 还提供了用于增加标签从对象的可恢复性的方法。 所述方法包括将标签剂掺入溶液中的步骤; 将包含标签剂的溶液与扰动剂混合以形成第一扰动标记剂溶液; 将第一扰动标记剂溶液与聚合物混合以形成第二扰动标记聚合物溶液; 以及将所述第二扰动标记聚合物溶液施加到所述物体的至少一部分以形成标记剂涂覆物体。 本发明还提供了用用于鉴定或追踪的DNA标记物标记物品的方法,其中所述方法包括提供包含DNA标记物的培养基,并且模制包含DNA标记的培养基以提供该物品的全部或部分。 DNA标记根据需要编码项目和/或项目模型唯一的信息。
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7.
公开(公告)号:US10059981B2
公开(公告)日:2018-08-28
申请号:US15079214
申请日:2016-03-24
申请人: APDN (B.V.I.) Inc.
IPC分类号: C12Q1/68 , C12Q1/6806
CPC分类号: C12Q1/6806 , C12Q1/68 , C12Q2563/185
摘要: The invention provides methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. Methods for authentication of a taggant marked object are also provided.
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公开(公告)号:US10760182B2
公开(公告)日:2020-09-01
申请号:US14572552
申请日:2014-12-16
申请人: APDN (B.V.I.) Inc.
IPC分类号: C12Q1/68 , D01B1/04 , D06M15/01 , D06M16/00 , D01G99/00 , D01B9/00 , D06H1/00 , D06M101/12 , D06M101/06
摘要: A method of marking fibers, wherein the method includes providing a plurality of fibers; depositing a marker onto at least a portion of the fibers, the depositing being performed with a delivery mechanism comprising one or more outlets; and thereby marking the fibers. Also provided is a device for marking fibers, including a transport system adapted to transport fibers in a direction of a marker delivery apparatus positioned along the transport system; the delivery apparatus includes one or more outlets, adapted to deposit a solution of the marker through the outlets onto at least a portion of the fibers; and thereby marking the fibers. Authentication of a fibrous material using the marking method of the invention followed obtaining a sample of the marked fibers and assaying the sample for the presence of the nucleic acid marker; and thereby determining whether the fibrous material is authentic or counterfeit.
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公开(公告)号:US10282480B2
公开(公告)日:2019-05-07
申请号:US15868510
申请日:2018-01-11
申请人: APDN (B.V.I.) INC.
发明人: Judith Murrah , Phidung H. Tran , Maciej B. Szczepanik , MingHwa Benjamin Liang , James A. Hayward
摘要: A system associated with authentication of an object related to a multi-mode marker using a processing device. The processing device performs operations that include detecting a signal associated with a multi-mode marker related with the object; assigning a digital code based on the detected signal associated with the multi-mode marker; and identifying the object based on the digital code related to authentication of the object. A corresponding method and computer-readable device are also disclosed.
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公开(公告)号:US20180142294A1
公开(公告)日:2018-05-24
申请号:US15800768
申请日:2017-11-01
申请人: APDN (B.V.I.) INC.
IPC分类号: C12Q1/6876 , G01N33/15 , G09F3/02
CPC分类号: C12Q1/6876 , C12Q1/68 , C12Q1/686 , G01N33/15 , G09F3/02 , G09F2003/0277 , C12Q2563/173 , C12Q2563/185
摘要: Provided is a method of authenticating an active pharmaceutical ingredient (API). The method includes providing an API or an API component and adding a nucleic acid marker having a nucleic acid marker sequence to produce a marked API or a marked API component. The presence of the nucleic acid marker is detected in the sample and the authenticity of the API is thereby determined according to whether the pharmaceutical product includes marked API or the marked API component.
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