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公开(公告)号:US20180297888A1
公开(公告)日:2018-10-18
申请号:US15995379
申请日:2018-06-01
发明人: Kensuke NAGAI , Tetsuya NAKASHIMA , Yutaka KUROIWA , Hiroyuki HIJIYA , Masamichi TANIDA , AKIO KOIKE , Manabu NISHIZAWA , Kazuo TSUBOTA , Toshihide KURIHARA , Hidemasa TORII
摘要: A wavelength-selective transmissive glass has a light transmittance Tmore than 315 nm and 400 nm or less at a wavelength of more than 315 nm and 400 nm or less represented by the formula shown below of 1% or more in terms of a plate thickness of 6 mm and a light transmittance T315 nm or less at a wavelength of 315 nm or less represented by the formula shown below of 60% or less in terms of a plate thickness of 6 mm. Ak is a weighting factor at a wavelength k (nm) for calculating T (light transmittance) defined in ISO-9050:2003, and Tk is a transmittance at the wavelength k (nm) in terms of a plate thickness of 6 mm: Tmore than 315 nm and 400 nm or less=(Σk=more than 315400 Ak×Tk)/(Σk=more than 315400 Ak) T315 nm or less=(Σk=300315 Ak×Tk)/(Σk=300315 Ak).
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2.
公开(公告)号:US20240210736A1
公开(公告)日:2024-06-27
申请号:US18600985
申请日:2024-03-11
IPC分类号: G02C7/06 , A01K67/02 , A61K9/00 , A61K31/575
CPC分类号: G02C7/06 , A01K67/02 , A61K9/0048 , A61K31/575 , A01K2227/105 , A01K2267/03
摘要: A model that closely resembles human excessive myopia can be prepared by mounting a minus lens (2) and a protector (4) to a juvenile mouse, the minus lens having an angle and a width adjustable in response to growth of the mouse. Further, this model analysis shows that myopia induction causes endoplasmic reticulum stress in a sclera and the endoplasmic reticulum stress induces myopia. Furthermore, it is revealed that an endoplasmic reticulum stress suppressant, particularly, phenylbutyrate and tauroursodeoxycholic acid act as a myopia prevention/suppression agent.
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公开(公告)号:US20240033311A1
公开(公告)日:2024-02-01
申请号:US18483161
申请日:2023-10-09
发明人: Kazuo TSUBOTA , Toshihide KURIHARA
IPC分类号: A61K36/16 , A61P27/10 , A61K9/00 , A61K31/05 , A61K31/202
CPC分类号: A61K36/16 , A61P27/10 , A61K9/0056 , A61K31/05 , A61K31/202
摘要: The ophthalmic composition effective for the prevention or treatment of myopia or ocular diseases are provided. In particular, the present invention provides an ophthalmic composition effective in a growing child or a young person in whom myopia develops and progresses, as well as a middle-aged and elderly person in whom age-related ocular diseases such as cataract, glaucoma, retinal detachment, retinopathy, maculopathy, choroidal neovascularization, posterior staphyloma, and optic neuropathy develop, a functional food containing the ophthalmic composition, and a screening method capable of searching for the same. [Solution] The above problem is solved by an ophthalmic composition or functional food product containing at least one component selected from the group consisting of crocetin and its pharmaceutically acceptable salts and ginkgo leaf extract.
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公开(公告)号:US20200171112A1
公开(公告)日:2020-06-04
申请号:US16614176
申请日:2018-05-15
发明人: Kazuo TSUBOTA , Toshihide KURIHARA
IPC分类号: A61K36/16 , A61K31/202 , A61K31/05 , A61K9/00 , A61P27/10
摘要: The ophthalmic composition effective for the prevention or treatment of myopia or ocular diseases are provided. In particular, the present invention provides an ophthalmic composition effective in a growing child or a young person in whom myopia develops and progresses, as well as a middle-aged and elderly person in whom age-related ocular diseases such as cataract, glaucoma, retinal detachment, retinopathy, maculopathy, choroidal neovascularization, posterior staphyloma, and optic neuropathy develop, a functional food containing the ophthalmic composition, and a screening method capable of searching for the same. [Solution] The above problem is solved by an ophthalmic composition or functional food product containing at least one component selected from the group consisting of crocetin and its pharmaceutically acceptable salts and ginkgo leaf extract.
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公开(公告)号:US20170168320A1
公开(公告)日:2017-06-15
申请号:US15366558
申请日:2016-12-01
CPC分类号: G02C7/104 , A61F2/16 , A61F9/00 , F21S2/00 , F21V9/00 , G02C7/00 , G02C7/02 , G02C7/04 , G02C11/04 , G02C2202/24
摘要: The purpose of the present invention is to provide a myopia prevention device. A myopia prevention device of the present invention comprises a light transmission part selected from a group consisting of an eyesight correcting tool, an eye protection tool, a face protection tool, a sunshade, a display device, a window, a wall, a light source covering, and a coating material. The light transmission part of the device transmits light having a wavelength within a range of 350 nm to 400 nm inclusive and thus suppresses the occurrence and progression of myopia. Further, a myopia prevention device comprises a light emission part selected from a group consisting of lighting equipment, a display device, and a light irradiation device. The light emission part of the device emits light having a wavelength within a range of 350 nm to 400 nm inclusive and thus suppresses the occurrence and progression of myopia.
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公开(公告)号:US20230364441A1
公开(公告)日:2023-11-16
申请号:US18026232
申请日:2021-09-16
发明人: Xiaoyan JIANG , Kiwako MORI , Toshihide KURIHARA , Kazuo TSUBOTA
IPC分类号: A61N5/06
CPC分类号: A61N5/0613 , A61N2005/0663
摘要: A device and a method for inhibiting thinning of a choroid. A choroidal thinning inhibiting device including a light source that emits violet light having a wavelength within a range from 360 nm to 400 nm, the choroidal thinning inhibiting device inhibiting thinning of a choroid by irradiation with the violet light. This device may further include a control mechanism that controls an irradiance and an irradiation time of the violet light, can be applied to ocular diseases selected from age-related macular degeneration, glaucoma, diabetic retinopathy, macular edema, eye strain, retinal vascular occlusion, triangle syndrome, central serous chorioretinopathy, retinitis pigmentosa, presbyopia, cataracts, and the like that are based on inadequate blood flow or reduced blood flow, and can be expected to prevent and treat such ocular diseases.
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公开(公告)号:US20210228901A1
公开(公告)日:2021-07-29
申请号:US17301859
申请日:2021-04-16
摘要: A light source for myopia prevention article includes a light emitter to emit light having an emission spectrum continuing from a first wavelength of not less than 360 nm nor more than 400 nm to a second wavelength of more than 400 nm.
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8.
公开(公告)号:US20200150457A1
公开(公告)日:2020-05-14
申请号:US16561776
申请日:2019-09-05
IPC分类号: G02C7/06 , A01K67/02 , A61K31/575 , A61K9/00
摘要: A model that closely resembles human excessive myopia can be prepared by mounting a minus lens (2) and a protector (4) to a juvenile mouse, the minus lens having an angle and a width adjustable in response to growth of the mouse. Further, this model analysis shows that myopia induction causes endoplasmic reticulum stress in a sclera and the endoplasmic reticulum stress induces myopia. Furthermore, it is revealed that an endoplasmic reticulum stress suppressant, particularly, phenylbutyrate and tauroursodeoxycholic acid act as a myopia prevention/suppression agent.
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