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公开(公告)号:US20080254506A1
公开(公告)日:2008-10-16
申请号:US11701883
申请日:2007-02-01
申请人: Adel Youakim , Robert F. DuBose , Steven R. Wiley
发明人: Adel Youakim , Robert F. DuBose , Steven R. Wiley
CPC分类号: C07K14/705 , A61K38/00 , C07K16/18 , G01N2500/02 , G01N2500/04
摘要: This invention relates to new members of the human Claudin polypeptide family, to methods of making such polypeptides, and to methods of using them to treat Claudin-associated conditions and to identify compounds that alter Claudin polypeptide activities.
摘要翻译: 本发明涉及人紧密连接蛋白多肽家族的新成员,制备这种多肽的方法,以及使用它们来治疗紧密连接蛋白相关病症并鉴定改变紧密连接蛋白多肽活性的化合物的方法。
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公开(公告)号:US07186802B2
公开(公告)日:2007-03-06
申请号:US10344487
申请日:2001-08-15
申请人: Adel Youakim , Robert F. DuBose , Steven R. Wiley
发明人: Adel Youakim , Robert F. DuBose , Steven R. Wiley
CPC分类号: C07K14/705 , A61K38/00 , C07K16/18 , G01N2500/02 , G01N2500/04
摘要: This invention relates to new members of the human Claudin polypeptide family, to methods of making such polypeptides, and to methods of using them to treat Claudin-associated conditions and to identify compounds that alter Claudin polypeptide activities.
摘要翻译: 本发明涉及人紧密连接蛋白多肽家族的新成员,制备这种多肽的方法,以及使用它们来治疗紧密连接蛋白相关病症并鉴定改变紧密连接蛋白多肽活性的化合物的方法。
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公开(公告)号:US20090226417A1
公开(公告)日:2009-09-10
申请号:US11890871
申请日:2007-08-08
申请人: Peter R. Baum , Robert F. DuBose , Steven R. Wiley
发明人: Peter R. Baum , Robert F. DuBose , Steven R. Wiley
IPC分类号: A61K39/395 , C07K16/18 , C12N15/11 , C12N15/00 , A61K38/16 , A61K39/00 , C12N5/06 , C12P21/04
CPC分类号: C07K14/70532 , A61K38/00 , A61K39/00
摘要: This invention relates to B7-H1.2 and Butryophilin 2/3, new members of the human B7 polypeptide family, methods of making such polypeptides, and to methods of using them to treat immunological conditions and to identify compounds that alter the activities of these human B7 polypeptides.
摘要翻译: 本发明涉及B7-H1.2和Butryophilin2/3,人类B7多肽家族的新成员,制备这种多肽的方法,以及使用它们来治疗免疫学病症和鉴定改变这些活性的化合物的方法 人B7多肽。
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公开(公告)号:US06958387B2
公开(公告)日:2005-10-25
申请号:US10094944
申请日:2002-03-08
IPC分类号: G01N33/50 , A61K38/00 , A61K38/55 , A61P1/16 , A61P7/02 , A61P11/00 , A61P17/00 , A61P17/06 , A61P17/08 , A61P19/02 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/08 , A61P43/00 , C07K14/47 , C07K14/81 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12P21/08 , G01N33/15 , G01N33/566 , C07K1/00 , C07H21/04 , C12N1/20 , C12P21/06
CPC分类号: C07K14/8121 , A61K38/00 , C07K2317/24 , G01N2333/8121
摘要: This invention relates to Thypin, a new member of the human serpin polypeptide family, methods of making Thypin polypeptides and using these polypeptides to treat various medical disorders and to methods of screening for compounds that agonize or antagonize Thypin polypeptide activities.
摘要翻译: 本发明涉及Thypin,人丝氨酸蛋白酶多肽家族的新成员,制备Thypin多肽和使用这些多肽治疗各种医学病症的方法以及筛选激动或拮抗Thypin多肽活性的化合物的方法。
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公开(公告)号:US07132264B2
公开(公告)日:2006-11-07
申请号:US11219282
申请日:2005-09-02
CPC分类号: C07K14/8121 , A61K38/00 , C07K2317/24 , G01N2333/8121
摘要: This invention relates to Thypin, a new member of the human serpin polypeptide family, methods of making Thypin polypeptides and using these polypeptides to treat various medical disorders and to methods of screening for compounds that agonize or antagonize Thypin polypeptide activities.
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公开(公告)号:US6130068A
公开(公告)日:2000-10-10
申请号:US181706
申请日:1998-10-28
CPC分类号: C07K14/705 , C07K14/71 , A61K38/00 , C07K2319/00 , C07K2319/02
摘要: The invention is directed to VESPR polypeptides as a purified and isolated protein, the DNA encoding the VESPR polypeptide, host cells transfected with cDNAs encoding VESPR, and methods for preparing VESPR polypeptides.
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公开(公告)号:US06187909B1
公开(公告)日:2001-02-13
申请号:US09459066
申请日:1999-12-10
IPC分类号: C07K1400
CPC分类号: C07K14/705 , A61K38/00 , C07K14/71 , C07K2319/00 , C07K2319/02
摘要: The invention is directed to VESPR polypeptides as a purified and isolated protein, the DNA encoding the VESPR polypeptide, host cells transfected with cDNAs encoding VESPR, and methods for preparing VESPR polypeptides.
摘要翻译: 本发明涉及作为纯化和分离的蛋白质的VESPR多肽,编码VESPR多肽的DNA,用编码VESPR的cDNA转染的宿主细胞,以及用于制备VESPR多肽的方法。
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公开(公告)号:US07214497B2
公开(公告)日:2007-05-08
申请号:US10294055
申请日:2002-11-13
IPC分类号: G01N33/53 , C07K14/475 , C07K14/435 , A61K38/18
CPC分类号: C07K14/705 , A61K38/00 , C07K14/71 , C07K2319/00 , C07K2319/02
摘要: The invention is directed to VESPR polypeptides as a purified and isolated protein, the DNA encoding the VESPR polypeptide, host cells transfected with cDNAs encoding VESPR, and methods for preparing VESPR polypeptides.
摘要翻译: 本发明涉及作为纯化和分离的蛋白质的VESPR多肽,编码VESPR多肽的DNA,用编码VESPR的cDNA转染的宿主细胞,以及用于制备VESPR多肽的方法。
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9.
公开(公告)号:US06562949B1
公开(公告)日:2003-05-13
申请号:US09459065
申请日:1999-12-10
IPC分类号: A61K39395
CPC分类号: C07K14/71 , A61K38/00 , C07K14/705 , C07K2319/00 , C07K2319/02
摘要: The invention is directed to VESPR polypeptides as a purified and isolated protein, the DNA encoding the VESPR polypeptide, host cells transfected with cDNAs encoding VESPR, and methods for preparing VESPR polypeptides.
摘要翻译: 本发明涉及作为纯化和分离的蛋白质的VESPR多肽,编码VESPR多肽的DNA,用编码VESPR的cDNA转染的宿主细胞,以及用于制备VESPR多肽的方法。
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公开(公告)号:US06174689B1
公开(公告)日:2001-01-16
申请号:US09458791
申请日:1999-12-10
IPC分类号: G01N3353
CPC分类号: C07K14/705 , A61K38/00 , C07K14/71 , C07K2319/00 , C07K2319/02
摘要: The invention is directed to VESPR polypeptides as a purified and isolated protein, the DNA encoding the VESPR polypeptide, host cells transfected with cDNAs encoding VESPR, and methods for preparing VESPR polypeptides.
摘要翻译: 本发明涉及作为纯化和分离的蛋白质的VESPR多肽,编码VESPR多肽的DNA,用编码VESPR的cDNA转染的宿主细胞,以及用于制备VESPR多肽的方法。
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