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13 条记录 (耗时 0.042 秒)

    Extendable rolled delivery system
    3.
    发明申请
    Extendable rolled delivery system 审中-公开
    可扩展轧制系统

    公开(公告)号：US20070196451A1

    公开(公告)日：2007-08-23

    申请号：US11358117

    申请日：2006-02-22

    申请人： Anurag Singhal ,  Robert Herrmann ,  Eun-Hyun Jang ,  Young-Ho Song

    发明人： Anurag Singhal ,  Robert Herrmann ,  Eun-Hyun Jang ,  Young-Ho Song

    IPC分类号： A61M31/00 ,  A61K9/70

    CPC分类号： A61M25/0082 ,  A61M25/0074 ,  A61M31/00

    摘要： The present invention relates to a device and method for delivery of a patch, graft, implant, therapeutic agent, or other device onto tissue using a rolled delivery mechanism. In one embodiment, a rolled delivery mechanism is provided for delivering a patch to tissue when the rolled delivery mechanism is unrolled. In another embodiment, a rolled delivery mechanism is provided for delivering therapeutic agent to a target tissue.

    摘要翻译： 本发明涉及一种用于使用轧制递送机构将补片，移植物，植入物，治疗剂或其它装置递送到组织上的装置和方法。 在一个实施例中，提供了一种轧制递送机构，用于在轧制的递送机构展开时将补片递送到组织。 在另一个实施方案中，提供了用于将治疗剂递送至靶组织的卷绕递送机构。

    Medical devices and methods for inhibiting smooth muscle cell proliferation
    6.
    发明申请
    Medical devices and methods for inhibiting smooth muscle cell proliferation 审中-公开
    用于抑制平滑肌细胞增殖的医学装置和方法

    公开(公告)号：US20050025808A1

    公开(公告)日：2005-02-03

    申请号：US10882070

    申请日：2004-06-29

    申请人： Robert Herrmann ,  James Barry ,  Kalpana Kamath

    发明人： Robert Herrmann ,  James Barry ,  Kalpana Kamath

    IPC分类号： A61L31/10 ,  A61L31/16 ,  A61F2/06

    CPC分类号： A61L31/10 ,  A61L31/16 ,  A61L2300/416

    摘要： The present invention relates generally to medical devices, preferably a stent, comprising an amount of one or more therapeutic agents, preferably paclitaxel, useful for preventing or treating a disease or condition associated with cell proliferation and/or migration. In particular, the invention relates to medical devices that is capable of releasing a cytostatic amount of paclitaxel that is effective to arrest smooth muscle cells in their G1/S phase without killing the cells. The medical devices can also release paclitaxel at a predetermined rate. Methods of making and using the medical devices are also provided.

    摘要翻译： 本发明一般涉及可用于预防或治疗与细胞增殖和/或迁移相关的疾病或病症的量的一种或多种治疗剂，优选紫杉醇的医疗装置，优选支架。 特别地，本发明涉及能够释放细胞抑制量的紫杉醇的医疗装置，其有效地在G1 / S期抑制平滑肌细胞而不杀死细胞。 医疗装置也可以以预定的速率释放紫杉醇。 还提供了制造和使用医疗装置的方法。

    Anti-thrombogenic and anti-restenotic vascular medical devices
    7.
    发明申请
    Anti-thrombogenic and anti-restenotic vascular medical devices 有权
    抗血栓形成和抗再狭窄的血管医疗器械

    公开(公告)号：US20060095120A1

    公开(公告)日：2006-05-04

    申请号：US10977695

    申请日：2004-10-29

    申请人： Robert Herrmann

    发明人： Robert Herrmann

    IPC分类号： A61F2/06

    CPC分类号： A61L31/10 ,  A61L31/16 ,  A61L2300/114 ,  A61L2300/416 ,  A61L2300/61

    摘要： A medical device is provided which is adapted for implantation or insertion into the vasculature. The medical device comprises the following: (a) a medical device substrate; (b) a lower polymeric layer, provided over the substrate, which comprises a nitric oxide donor and a polymer; and (c) an upper polymeric layer, provided over the lower polymer layer, which comprises a polymer and an anti-restenotic agent.

    摘要翻译： 提供适于植入或插入脉管系统的医疗装置。 该医疗装置包括：（a）医疗器械基板; （b）提供在基底上的下聚合物层，其包含一氧化氮供体和聚合物; 和（c）设置在下聚合物层上的上聚合物层，其包含聚合物和抗再狭窄剂。

    WHEELCHAIR ASSEMBLY
    8.
    发明申请
    WHEELCHAIR ASSEMBLY 审中-公开

    公开(公告)号：US20190298596A1

    公开(公告)日：2019-10-03

    申请号：US16366893

    申请日：2019-03-27

    申请人： Robert Herrmann

    发明人： Robert Herrmann

    IPC分类号： A61G5/12

    摘要： An improved wheelchair assembly structured and arrange to equip a standard manual wheelchair with larger front wheels giving the user added leverage and control when maneuvering their chair.

    Apparatuses and methods to treat atherosclerotic plaques
    9.
    发明申请
    Apparatuses and methods to treat atherosclerotic plaques 审中-公开
    治疗动脉粥样硬化斑块的装置和方法

    公开(公告)号：US20080085294A1

    公开(公告)日：2008-04-10

    申请号：US11538683

    申请日：2006-10-04

    申请人： Toby Freyman ,  Robert Herrmann ,  Wendy Naimark ,  Maria Palasis

    发明人： Toby Freyman ,  Robert Herrmann ,  Wendy Naimark ,  Maria Palasis

    IPC分类号： A61F2/00

    CPC分类号： A61L31/16 ,  A61L31/148 ,  A61L2300/604

    摘要： This invention comprises an apparatus for treating an atherosclerotic plaque in a coronary artery of a mammal by placing at or proximate to an entrance to the coronary artery and upstream of the vulnerable plaque, and an effective amount of a therapeutic agent for the treatment of the plaque. This invention comprises delivering a deposition of a therapeutic drug high in the coronary arterial tree for treatment of downstream vulnerable plaques. The invention also comprises slow release formulation and delivery of an apparatus that is totally degradable or removed and/or replaced.

    摘要翻译： 本发明包括一种用于通过放置在冠状动脉入口处或接近于冠状动脉入口处和易损斑块上游来治疗哺乳动物冠状动脉中的动脉粥样硬化斑块的装置，以及有效量的用于治疗斑块的治疗剂 。 本发明包括在冠状动脉树中输送高度治疗药物的沉积物以治疗下游脆弱斑块。 本发明还包括缓释制剂和递送完全可降解或除去和/或更换的装置。

    Composite wall structure
    10.
    发明申请
    Composite wall structure 失效
    复合墙结构

    公开(公告)号：US20060117675A1

    公开(公告)日：2006-06-08

    申请号：US11297043

    申请日：2005-12-08

    申请人： Robert Herrmann

    发明人： Robert Herrmann

    IPC分类号： E04B7/08

    CPC分类号： E04B1/32 ,  B63B3/13 ,  B64B1/08 ,  E04B2001/327 ,  E04H5/00

    摘要： A composite wall structure for use in a building, such as a geodesic dome, or the outer hull of a pressurized vehicle, such as an airship or submarine, is formed by interconnecting a plurality of three dimensional triangular shaped cells into a shape of desired contour, such as planar or curved, with each individual cell having a sealed chamber that is pressurized, and securing a fluid impervious closure skin to the connected array of cells. Each cell is formed by connecting planar rectangular sidewalls into a triangular frame having opposite sides and attaching a planar triangular panel to each side of the frame in a manner to form a pressure sealed chamber. The hull structure of predetermined shape is capable of captivating a volume of air and/or resisting buckling or failure resulting from fluid pressure on the hull during operation in air or water environments.

    摘要翻译： 通过将多个三维三角形的单元互连成所需轮廓的形状，形成用于诸如测地圆顶的建筑物中的复合壁结构或加压车辆的诸如飞艇或潜艇的外壳 ，例如平面或弯曲的，其中每个单独的单元具有被加压的密封室，并且将不透液体的封闭皮肤固定到连接的单元阵列上。 每个单元通过将平面矩形侧壁连接成具有相对侧的三角形框架并且以形成压力密封室的方式将平面三角形面板附接到框架的每一侧而形成。 预定形状的船体结构能够在空气或水环境中操作期间吸引一定体积的空气和/或抵抗由船体上的流体压力引起的弯曲或破坏。