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公开(公告)号：US07666139B2
公开(公告)日：2010-02-23
申请号：US10682733
申请日：2003-10-10
CPC分类号： A61B8/481
摘要： An ultrasonic imaging apparatus, including an ultrasonic probe including an ultrasonic vibration element configured to transmit and receive an ultrasonic wave in a scanning direction in an object in which a contrast media has been injected; a transmission unit configured to apply successive drive pulses to the probe so as to transmit respective ultrasonic signals in respective rate sections; a reception unit configured to receive reflected ultrasonic signals, including first reflected ultrasonic signals produced by a first drive pulse in a first rate section and reflected back to the probe in the first rate section and in a second rate section subsequent to the first rate section; an operation unit configured to perform an operation including at least one of addition and subtraction of at least two of the first ultrasonic signals received during different rate sections; and a signal processor configured to produce image data based on the result of the operation performed by the operation unit. Plural driving pulses having alternating polarity may be applied to the probe in a same scan direction.
摘要翻译： 一种超声波成像装置，包括：超声波探头，其包括超声波振动元件，所述超声波振动元件被配置为在已经注射了造影剂的物体中沿扫描方向发送和接收超声波; 发送单元，被配置为向所述探针施加连续的驱动脉冲，以便在各个速率区间中发送各自的超声波信号; 接收单元，被配置为接收反射超声波信号，所述反射超声波信号包括由第一速率部分中的第一驱动脉冲产生的第一反射超声波信号，并且被反射回到第一速率部分中的探头和在第一速率部分之后的第二速率部分中; 操作单元，被配置为执行包括在不同速率区段期间接收的所述第一超声波信号中的至少两个的加法和减法中的至少一个的操作; 以及信号处理器，被配置为基于由所述操作单元执行的操作的结果来产生图像数据。 具有交替极性的多个驱动脉冲可以以相同的扫描方向施加到探针。
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公开(公告)号：US20070197916A1
公开(公告)日：2007-08-23
申请号：US11627667
申请日：2007-01-26
IPC分类号： A61B8/14
CPC分类号： A61B8/463 , A61B8/06 , A61B8/481 , G01S7/52046 , G01S7/52074 , G01S15/8927 , G01S15/8952
摘要： An ultrasonic diagnostic apparatus comprises a first reception echo obtaining unit, a second reception echo obtaining unit, a reception echo combining unit, and an image generating unit. The first reception echo obtaining unit transmits a plurality of ultrasonic pulses having frequency spectra different from one another to an object, and obtains each of reception echoes corresponding to the plurality of ultrasonic pulses. The second reception echo obtaining unit transmits an ultrasonic pulse having the same frequency component characteristics as an combined pulse obtained by combining the plurality of ultrasonic pulses, and to obtain an reception echo. The reception echo combining unit combines the reception echoes obtained by the first reception echo obtaining unit and the reception echo obtained by the second reception echo obtaining unit to generate a combined signal. The image generating unit generates an image of echoes reflected from the object on the basis of the combined signal.
摘要翻译： 超声波诊断装置包括第一接收回波获取单元，第二接收回波获取单元，接收回声合成单元和图像生成单元。 第一接收回波获取单元将具有彼此不同的频谱的多个超声波脉冲发送到对象，并且获得与多个超声波脉冲对应的每个接收回波。 第二接收回波获取单元发送具有与通过组合多个超声波脉冲而获得的组合脉冲相同的频率分量特性的超声波脉冲，并获得接收回波。 接收回声组合单元将由第一接收回声获得单元获得的接收回声与由第二接收回波获取单元获得的接收回波组合以产生组合信号。 图像生成单元基于合成信号生成从物体反射的回波的图像。
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公开(公告)号：US08932225B2
公开(公告)日：2015-01-13
申请号：US11627667
申请日：2007-01-26
CPC分类号： A61B8/463 , A61B8/06 , A61B8/481 , G01S7/52046 , G01S7/52074 , G01S15/8927 , G01S15/8952
摘要： An ultrasonic diagnostic apparatus comprises a first reception echo obtaining unit, a second reception echo obtaining unit, a reception echo combining unit, and an image generating unit. The first reception echo obtaining unit transmits a plurality of ultrasonic pulses having frequency spectra different from one another to an object, and obtains each of reception echoes corresponding to the plurality of ultrasonic pulses. The second reception echo obtaining unit transmits an ultrasonic pulse having the same frequency component characteristics as an combined pulse obtained by combining the plurality of ultrasonic pulses, and to obtain an reception echo. The reception echo combining unit combines the reception echoes obtained by the first reception echo obtaining unit and the reception echo obtained by the second reception echo obtaining unit to generate a combined signal. The image generating unit generates an image of echoes reflected from the object on the basis of the combined signal.
摘要翻译： 超声波诊断装置包括第一接收回波获取单元，第二接收回波获取单元，接收回声合成单元和图像生成单元。 第一接收回波获取单元将具有彼此不同的频谱的多个超声波脉冲发送到对象，并且获得与多个超声波脉冲对应的每个接收回波。 第二接收回波获取单元发送具有与通过组合多个超声波脉冲而获得的组合脉冲相同的频率分量特性的超声波脉冲，并获得接收回波。 接收回声组合单元将由第一接收回声获得单元获得的接收回声与由第二接收回波获取单元获得的接收回波组合以产生组合信号。 图像生成单元基于合成信号生成从物体反射的回波的图像。
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公开(公告)号：US08485977B2
公开(公告)日：2013-07-16
申请号：US12414290
申请日：2009-03-30
申请人： Makoto Hirama
发明人： Makoto Hirama
IPC分类号： A61B8/00
CPC分类号： G01S7/52046 , G01S7/52047 , G01S7/52095 , G01S15/8927 , G01S15/8997
摘要： An ultrasound diagnosis apparatus that can acquire ultrasound image data having excellent spatial resolution and contrast resolution by electrically controlling focusing points of transmission/reception waves so as to form transmitting beams and receiving beams having substantially uniform thin beam width along an elevation direction. Ultrasounds emitted from a prescribed number of transducers are focused at a hypothetical point sound source. Wave-fronts reflect at a plurality of observing points. Ultrasounds reflected at the observing points are received through a prescribed number of transducers generating a plurality of channels of receiving signals, which are focused by performing phase compensation and summation so that the observing point becomes a reception focusing point. The receiving signals are focused to correct transmitting delays due to propagation distances between the transmitting focusing point and the observing points.
摘要翻译： 一种超声波诊断装置，其可以通过电控制发送/接收波的聚焦点来获取具有优异的空间分辨率和对比度分辨率的超声图像数据，从而沿着仰角方向形成具有基本均匀的薄波束宽度的发射波束和接收波束。 从规定数量的换能器发射的超声波聚焦在假想点声源。 波前反映在多个观察点。 通过规定数量的换能器接收观测点反射的超声波，产生多个接收信号的信道，通过执行相位补偿和求和来使焦点成为接收聚焦点。 接收信号被聚焦以校正由于发射聚焦点和观测点之间的传播距离引起的传输延迟。
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公开(公告)号：US5574324A
公开(公告)日：1996-11-12
申请号：US396787
申请日：1995-03-01
申请人： Makoto Hirama , Kenji Ishihara , Susumu Sasaki , Yoshiaki Honda
发明人： Makoto Hirama , Kenji Ishihara , Susumu Sasaki , Yoshiaki Honda
CPC分类号： H02K3/528
摘要： Plural thin plate projecting portions are integrally and projectingly provided on an outer peripheral portion of a side plate member of a bobbin. Each of the thin plate projecting portions comprises a circumferential rib, a slit portion and a reinforcement rib. The circumferential rib is provided on an outer peripheral face of the thin plate projecting portion of the bobbin and then a gap is formed between a claw-shaped magnetic pole of a rotor core and the thin plate projecting portion. A varnish material etc. is caused to adhere to and harden in this gap. By filling a root portion of the claw-shape magnetic pole of the rotor core with varnish material, the resonance vibration in the rotor core can be restrained. As a result, an alternating current generator for use in a vehicle having the small magnetic noise can be obtained.
摘要翻译： 多个薄板突出部分一体地突出地设置在线轴的侧板构件的外周部上。 每个薄板突出部分包括周向肋，狭缝部分和加强肋。 圆周肋设置在线轴的薄板突出部的外周面上，然后在转子芯的爪形磁极与薄板突出部之间形成间隙。 导致清漆材料等粘附并硬化在该间隙中。 通过用清漆材料填充转子芯的爪状磁极的根部，能够抑制转子铁芯中的共振。 结果，可以获得用于具有小磁噪声的车辆中的交流发电机。
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6.发明授权Cell culture membrane, cell culture substrate, and method for manufacturing cell culture substrate 有权细胞培养膜，细胞培养基质和细胞培养基质的制造方法公开(公告)号：US09492842B2
公开(公告)日：2016-11-15
申请号：US14128089
申请日：2012-06-22
申请人： Yasuo Yoshimoto , Kentaro Kamimae , Yuki Tanabe , Taku Oguni , Takashi Inoue , Tsutomu Mochizuki , Makoto Hirama , Teruo Fujii , Hiroshi Kimura , Hideto Tozawa
发明人： Yasuo Yoshimoto , Kentaro Kamimae , Yuki Tanabe , Taku Oguni , Takashi Inoue , Tsutomu Mochizuki , Makoto Hirama , Teruo Fujii , Hiroshi Kimura , Hideto Tozawa
CPC分类号： B05D1/60 , C12M23/20 , C12M25/02 , C12N5/0068 , C12N2533/30
摘要： Provided is: a cell culture membrane, which is free from materials derived from living organisms, can easily be industrially mass-produced, exhibits superior long-term storage properties and chemical resistance, has excellent cell adhesion properties and long-term culture properties and is capable of replicating a cell adhesion morphology that is similar to that of collagen derived from living organisms and being used for conventional cell cultivation. Also provided are a cell culture substrate, and a method for manufacturing the cell culture substrate. In the present invention, as a cell adhesion layer, a polymer membrane represented by formula (I) is formed on the base of a cell culture substrate so as to have a membrane thickness equal to or greater than 0.2 μm (in the formula, R1 and R2 represent a —(CH2)n—NH2 moiety (n is an integer of 1-10 inclusive.) or H, with at least one of R1 and R2 being a —(CH2)n—NH2 moiety. Moreover, l and m are positive integers expressing polymerization degree).
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公开(公告)号：US08310212B2
公开(公告)日：2012-11-13
申请号：US12571821
申请日：2009-10-01
申请人： Shoju Masumoto , Hiroshi Yoneda , Makoto Hirama , Shuichi Kokubun
发明人： Shoju Masumoto , Hiroshi Yoneda , Makoto Hirama , Shuichi Kokubun
IPC分类号： H02P9/00
CPC分类号： H02J7/163 , H02J7/166 , H02P9/48 , H02P2101/30 , H02P2101/45
摘要： This invention provides a control device for automobile battery-charging generators, adapted to supply a plurality of sets of specifications in a highly reliable and stable form by simple switching between electrical characteristics assigning and limiting functions so as to meet various needs of users. In accordance with a voltage of a battery B, a voltage control IC regulator 120 controls a field current flowing through a field winding FL. The voltage control IC regulator 120 has a plurality of functions for assigning electrical characteristics limits or electrical characteristics beforehand. The voltage control IC regulator 120 also has switch terminals SW1 and SW2 that switch the plurality of functions that assign the electrical characteristics limits or the electrical characteristics. Electric potential levels of the switch terminals SW1 and SW2 can be changed by cutting cutoff portions CP1 and CP2 of an intermediate terminal 150 or leaving these cutoff portions connected. Thus, an effective or ineffective state of the functions that assign the electrical characteristics limits or the electrical characteristics can be switched.
摘要翻译： 本发明提供了一种用于汽车电池充电发电机的控制装置，其适于通过在电特性分配和限制功能之间的简单切换来以高度可靠和稳定的形式提供多组规格，以满足用户的各种需要。 根据电池B的电压，电压控制IC调节器120控制流过励磁绕组FL的励磁电流。 电压控制IC调节器120具有预先分配电特性限制或电特性的多种功能。 电压控制IC调节器120还具有开关端子SW1和SW2，其切换分配电特性限制或电特性的多个功能。 可以通过切断中间端子150的截止部分CP1和CP2或使这些切断部分连接来改变开关端子SW1和SW2的电位电平。 因此，可以切换分配电特性限制或电特性的功能的有效或无效状态。
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公开(公告)号：US06258030B1
公开(公告)日：2001-07-10
申请号：US09516379
申请日：2000-03-01
申请人： Makoto Hirama
发明人： Makoto Hirama
IPC分类号： A61B800
CPC分类号： G01S15/8993 , A61B8/14 , G01S7/52025 , G10K11/346 , Y10S128/916
摘要： The present invention discloses a three-dimensional ultrasonic diagnostic apparatus that makes it possible to reduce the cost of the apparatus and reduce power consumption by decreasing the number of delay circuits to be used for forming reception beams from reflection waves. An ultrasonic diagnostic apparatus of the present invention includes a three-dimensional ultrasonic scanning unit for carrying out a three-dimensional ultrasonic scanning by a plurality of ultrasonic transducers arranged two-dimensionally and for forming detection signals corresponding to reflection waves reflected from a subject that received waves applied by the transducers, a first delay add processing unit for dividing detection signal from all the transducers into a predetermined plurality of partial signal groups and for carrying out delay add processing to each of the divided partial signal groups to form a first delay adding signal, a second delay add processing unit for carrying out a delay add processing to the first delay adding signal output from the first delay add processing unit to form a second delay adding signal, and an image processing unit for reconstructing a three-dimensional image according to the second delay adding signal output from the second delay add processing unit. Based on this arrangement, it is possible to achieve a parallel simultaneous reception processing of a three-dimensional scanning with a small number of delay circuits. This facilitates a real-time display of the three-dimensional ultrasonic diagnostic apparatus.
摘要翻译： 本发明公开了一种三维超声波诊断装置，通过减少用于形成来自反射波的接收光束的延迟电路的数量，能够降低装置的成本并降低功耗。 本发明的超声波诊断装置包括：三维超声波扫描单元，用于通过二维布置的多个超声波换能器进行三维超声波扫描，并且形成对应于从接收到的被摄体反射的反射波的检测信号 由换能器施加的波;第一延迟加法处理单元，用于将来自所有换能器的检测信号分成预定的多个部分信号组，并对每个分割的部分信号组执行延迟加法处理，以形成第一延迟加法信号 第二延迟添加处理单元，用于对从第一延迟添加处理单元输出的第一延迟添加信号执行延迟添加处理，以形成第二延迟加法信号;以及图像处理单元，用于根据 第二个延迟添加信号从第二个延迟添加过程输出 唱歌单位 基于这种布置，可以实现具有少量延迟电路的三维扫描的并行同时接收处理。 这有助于三维超声波诊断装置的实时显示。
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公开(公告)号：US5186175A
公开(公告)日：1993-02-16
申请号：US725805
申请日：1991-07-10
申请人： Makoto Hirama , Takashi Kumazawa
发明人： Makoto Hirama , Takashi Kumazawa
CPC分类号： G10K11/345 , G01S15/8925
摘要： In an ultrasonic diagnostic apparatus in which ultrasonic echo beams is focused three-dimensionally, a probe employs plural transducers arranged in two directions, lateral and azimuth directions. The transducers arranged in each azimuth direction are connected to a transmitting-receiving channel in a transmitting-receiving portion via a switch circuit. The switch circuit operates on the control of a switching controller and can connect a transducer selected by the controller in the azimuth direction to the transmitting-receiving channel. Output signals from the transmitting-receiving portion are supplied to a signal processing portion, in which beam forming for three-dimension echo beams is carried out by using a beam former. Thus, transducers arranged on each line in the lateral direction can be driven simultaneously, resulting in a more compact circuit and a reduced number of transmitting and receiving for better real-time processing. Further, the beam former is devided into two stage, one for the lateral direction and the other for the azimuth direction. This combination of two beam formers lead to adjustable focuses in the both direction in addition to a reduced memory capacity in the signal processing.
摘要翻译： 在超声波诊断装置中，超声波回波束被三维聚焦，探针使用沿两个方向排列的多个换能器，横向和方位方向。 在每个方位方向上布置的换能器通过开关电路连接到发送接收部分中的发送接收信道。 开关电路通过开关控制器的控制进行工作，并且可以将由控制器选择的方位方向上的换能器连接到发送接收通道。 来自发送接收部分的输出信号被提供给信号处理部分，其中通过使用波束形成器来执行用于三维回波波束的波束形成。 因此，可以同时驱动排列在横向上的每一行上的换能器，从而导致更紧凑的电路和减少的发送和接收数量以实现更好的实时处理。 此外，波束形成器分为两个级，一个用于横向，另一个用于方位角方向。 除了在信号处理中减少的存储容量之外，两个光束形成器的这种组合导致两个方向上的可调聚焦。
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公开(公告)号：US08241218B2
公开(公告)日：2012-08-14
申请号：US12179093
申请日：2008-07-24
申请人： Makoto Hirama
发明人： Makoto Hirama
IPC分类号： A61B8/14
CPC分类号： G01S15/8909 , A61B8/00 , A61B8/483 , G01S7/52085 , G01S15/8945 , G01S15/8993
摘要： A probe includes a transducer unit including a plurality of transducers which are arrayed in the first direction, transmit ultrasonic waves and receive echo signals, and a moving mechanism for continuously moving the transducer unit in the second direction crossing the first direction. A movement control unit controls the moving mechanism to continuously move the transducer unit in the second direction. A transmission unit causes the transducer unit to generate ultrasonic waves. A scan line signal generation unit generates a plurality of actual measurement scan line signals by delaying and adding a plurality of echo signals from the transducer unit. A scan line signal calculation unit calculates a plurality of mathematical scan line signals constituting a plurality of mathematical electronic scan planes from the plurality of actual measurement scan line signals. An image generation unit generates multislice tomograms on the basis of the plurality of calculated mathematical scan line signals.
摘要翻译： 探头包括：换能器单元，包括沿第一方向排列的多个换能器，发送超声波和接收回波信号;以及移动机构，用于沿与第一方向交叉的第二方向连续移动换能器单元。 移动控制单元控制移动机构沿第二方向连续移动换能器单元。 传输单元使得换能器单元产生超声波。 扫描线信号生成单元通过延迟并添加来自换能器单元的多个回波信号来生成多个实际的测量扫描线信号。 扫描线信号计算单元从多个实际测量扫描线信号中计算构成多个数学电子扫描平面的多个数学扫描线信号。 图像生成单元基于多个计算出的数学扫描线信号生成多层次断层图像。
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