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16 条记录 (耗时 0.022 秒)

    Monoclonal antibody recognizing C-terminus of hBNP
    2.
    发明授权
    Monoclonal antibody recognizing C-terminus of hBNP 失效
    识别hBNP的C末端的单克隆抗体

    公开(公告)号：US06677124B2

    公开(公告)日：2004-01-13

    申请号：US09942709

    申请日：2001-08-31

    申请人： Tetsuo Tsuji ,  Ken Inouye ,  Akira Yamauchi ,  Masao Kono ,  Ken'ichi Igano

    发明人： Tetsuo Tsuji ,  Ken Inouye ,  Akira Yamauchi ,  Masao Kono ,  Ken'ichi Igano

    IPC分类号： G01N3353

    CPC分类号： C07K16/26

    摘要： A hybridoma producing a monoclonal antibody recognizing the C-terminus of human brain natriuretic peptide (hBNP) was cultivated in a medium or the abdominal cavity of a mouse to recover the monoclonal antibody from the medium or ascites accumulated in the abdominal cavity. An immunoassay for hBNP was established using the monoclonal antibody. The immunoassay for hBNP of the invention is so sensitive that the minimum detection limit is 1 pg/ml and can therefore determine the hBNP level in blood plasma directly, without the extraction of hBNP from blood plasma. It is useful for diagnosing diseases such as hypertension and the like, and states of the heart, kidney, and the like by using the increase/decrease of the hBNP level as an index.

    摘要翻译： 在小鼠的培养基或腹腔中培养产生识别人脑钠尿肽（hBNP）的C末端的单克隆抗体的杂交瘤，以从腹腔积聚的培养基或腹水中回收单克隆抗体。 使用单克隆抗体建立了hBNP的免疫测定。 本发明的hBNP的免疫测定非常敏感，最小检测限为1pg / ml，因此可以直接测定血浆中的hBNP水平，而不从血浆中提取hBNP。 通过使用hBNP水平的增加/减少作为指标，诊断高血压等疾病，心脏和肾脏等的状态是有用的。

    4- or 6-substituted aldosterones
    4.
    发明授权
    4- or 6-substituted aldosterones 失效
    4-或6-取代醛固酮

    公开(公告)号：US4623485A

    公开(公告)日：1986-11-18

    申请号：US493280

    申请日：1983-05-10

    申请人： Masao Kono ,  Taichitro Komeno ,  Shoichi Ishihara ,  Akira Yamauchi ,  Tadashi Okabayashi

    发明人： Masao Kono ,  Taichitro Komeno ,  Shoichi Ishihara ,  Akira Yamauchi ,  Tadashi Okabayashi

    IPC分类号： G01N33/53 ,  C07J71/00 ,  G01N33/74 ,  C07J41/00 ,  C07J43/00

    CPC分类号： C07J71/0005 ,  G01N33/743 ,  Y02P20/55 ,  Y10S435/81 ,  Y10S435/961 ,  Y10S435/964 ,  Y10S435/975 ,  Y10S436/804 ,  Y10S436/817

    摘要： A substituted aldosterone of the formula: ##STR1## wherein either one of R.sup.1 and R.sup.2 is hydrogen and the other is --S(CH.sub.2).sub.m COR.sup.3 or --OCO(CH.sub.2).sub.n COR.sup.3, provided that when R.sup.1 is hydrogen, R.sup.2 is --S(CH.sub.2).sub.m COR.sup.3 or --OCO(CH.sub.2).sub.n COR.sup.3 and when R.sup.2 is hydrogen, R.sup.1 is --S(CH.sub.2).sub.m COR.sup.3 ; m being an integer from 1 to 3, n being an integer from 1 to 5 and R.sup.3 being hydroxyl, lower alkoxy or a residue of tyramine, tyrosine lower alkyl ester, histamine, histidine, 7-aminoheptanoyltyrosine lower alkyl ester or .beta.-D-galactosidase as optionally iodinated, or its (18-20)-acetal 20,21-ketonide, which is useful as the reagent in determination of aldosterones by radioimmunoassay or enzyme immunoassay.

    摘要翻译： 下式的取代醛固酮：其中R 1和R 2中的任一个是氢，另一个是-S（CH 2）m COR 3或-OCO（CH 2）n COOR 3，条件是当R 1是氢时，R 2是 - S（CH2）mCOR3或-OCO（CH2）nCOR3，当R2为氢时，R1为-S（CH2）mCOR3; m为1至3的整数，n为1至5的整数，R3为羟基，低级烷氧基或酪胺残基，酪氨酸低级烷基酯，组胺，组氨酸，7-氨基庚酰基酪氨酸低级烷基酯或β-D- 或其（18-20） - 缩醛20,21-酮二酮，其可用作通过放射免疫测定或酶免疫测定法测定醛固酮的试剂。

    Method for effecting registration for a copying apparatus
    6.
    发明授权
    Method for effecting registration for a copying apparatus 失效
    实现复印装置的登记的方法

    公开(公告)号：US4417806A

    公开(公告)日：1983-11-29

    申请号：US319108

    申请日：1981-11-06

    申请人： Tatsuo Tani ,  Masao Kono

    发明人： Tatsuo Tani ,  Masao Kono

    IPC分类号： G03G15/041 ,  G03G15/22

    CPC分类号： G03G15/041

    摘要： In copying apparatus having a magnification ratio varying device, wherein a photosensitive member in motion is exposed to an optical image of an original by slit exposing to form an electrostatic latent image thereon and the original scanning velocity is varied in accordance with the magnification ratio selected, it is necessary to effect registration of the forward end of the image of an original with the leading end of a photosensitive sheet or a transfer-printing sheet. The above-mentioned registration is effected by delivering a copy sheet after lapse of a predetermined period of time following the production of a detection signal by a detector, the above-mentioned predetermined period of time being varied in conformity with the selected one of magnification ratios.

    摘要翻译： 在具有放大率变化装置的复印装置中，其中通过狭缝曝光将运动中的感光构件暴露于原稿的光学图像以在其上形成静电潜像，并且原始扫描速度根据所选择的倍率而变化， 必须使感光片或转印印刷用纸的前端的原稿的前端的前端进行配准。 上述登记通过在检测器产生检测信号之后经过预定时间段之后递送复印纸来实现，上述预定时间段根据所选择的一个放大率而变化 。

    Original feed apparatus for electrophotographic copying machine
    8.
    发明授权
    Original feed apparatus for electrophotographic copying machine 失效
    电子照相复印机原装进给装置

    公开(公告)号：US4194837A

    公开(公告)日：1980-03-25

    申请号：US964876

    申请日：1978-11-30

    申请人： Tatsuo Tani ,  Sakae Ota ,  Masao Kono

    发明人： Tatsuo Tani ,  Sakae Ota ,  Masao Kono

    IPC分类号： G03B27/62 ,  B65H5/22

    CPC分类号： G03B27/6257

    摘要： A multi-mode copying machine capable of effecting copying in accordance with a sheet mode copying system and a book mode copying system is provided with an original feed apparatus having means for guiding conveyor belts to deflect away from an original irradiation position in their travel, the conveyor belts being adapted to transport an original in sheet form. Further, the original feed apparatus has means for transporting an original in sheet form exactly at a predetermined rate in the sheet mode copying system and for transporting the original without deformation or breakage while being fed at a high rate in the book mode copying system.

    摘要翻译： 能够根据纸张模式复印系统和书本模式复印系统进行复印的多模式复印机设置有原稿进给装置，该原稿进给装置具有用于引导输送带在其行进中偏离原始照射位置的装置， 输送带适于以原纸形式运输原件。 此外，原稿进给装置具有用于在纸张模式复印系统中以预定速率精确地传送原稿的原稿，并且在书本模式复印系统中以高速率进给的同时传送原稿而没有变形或破损的装置。

    Liquid crystal display device and resistor type touch panel
    9.
    发明授权
    Liquid crystal display device and resistor type touch panel 有权
    液晶显示装置和电阻式触摸屏

    公开(公告)号：US06633279B1

    公开(公告)日：2003-10-14

    申请号：US09611369

    申请日：2000-07-06

    申请人： Masao Kono ,  Shinsaku Chiba

    发明人： Masao Kono ,  Shinsaku Chiba

    IPC分类号： G09G508

    CPC分类号： G06F3/0412 ,  G02F1/13338 ,  G06F3/045

    摘要： A touch panel including an upper substrate (4A) consisting of a soft film having an upper resistor film (51) and a lower substrate of a hard plate having a lower resistor film, which are bonded together to face each other. The touch panel provides a detection output representing the position of contact between the upper resistor film (51) and the lower resistor film as two-dimensional coordinate values. Either the upper resistor film (51) or the lower resistor film or both are of a comb shape having a plurality of resistive lines with a common connector (41) at one end.

    摘要翻译： 包括由具有上电阻膜（ 51 PDAT>）的软膜组成的上基板（ 4 A） 以及具有下电阻膜的硬板的下基板，它们彼此结合在一起。 触摸面板提供表示上电阻膜（ 51 ）与下电阻膜之间的接触位置的检测输出作为二维坐标值。 上电阻膜（ 51 ）或下电阻膜或两者都是具有多个具有公共连接器的电阻线（ 41 ）。

    Method for effecting registration for a copying apparatus
    10.
    发明授权
    Method for effecting registration for a copying apparatus 失效
    实现复印装置的登记的方法

    公开(公告)号：US4217052A

    公开(公告)日：1980-08-12

    申请号：US877818

    申请日：1978-02-14

    申请人： Tatsuo Tani ,  Masao Kono

    发明人： Tatsuo Tani ,  Masao Kono

    IPC分类号： G03G15/041 ,  G03G15/30 ,  G03G15/00

    CPC分类号： G03G15/30 ,  G03G15/041

    摘要： In copying apparatus having a magnification ratio varying device, wherein a photosensitive member in motion is exposed to an optical image of an original by slit exposing to form an electrostatic latent image thereon and the original scanning velocity is varied in accordance with the magnification ratio selected, it is necessary to effect registration of the forward end of the image of an original with the leading end of a photosensitive sheet or a transfer-printing sheet.The above-mentioned registration is effected by delivering a copy sheet simultaneously as or after lapse of a predetermined time following the production of a detection signal by a detection means, which detecting position is varied in accordance with the magnification ratio selected.

    摘要翻译： 在具有放大率变化装置的复印装置中，其中通过狭缝曝光将运动中的感光构件暴露于原稿的光学图像以在其上形成静电潜像，并且原始扫描速度根据所选择的倍率而变化， 必须使感光片或转印印刷用纸的前端的原稿的前端的前端进行配准。 通过检测装置产生检测信号之后或之后经过预定时间同时输送上述登记，该检测位置根据所选择的倍率而变化。