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    Novel radioactive estradienes labelled with iodine
    1.
    发明授权
    Novel radioactive estradienes labelled with iodine 失效
    用碘标记的新型放射性碘化物

    公开(公告)号：US4639336A

    公开(公告)日：1987-01-27

    申请号：US620455

    申请日：1984-06-14

    申请人： Alain Jouquey ,  Jean Salmon ,  Michel Mouren ,  Gaetan Touyer

    发明人： Alain Jouquey ,  Jean Salmon ,  Michel Mouren ,  Gaetan Touyer

    IPC分类号： C07J41/00 ,  G01N33/534 ,  G01N33/74 ,  C07J1/00

    CPC分类号： C07J41/0016 ,  C07J41/0083 ,  G01N33/534 ,  G01N33/743 ,  A61K2123/00

    摘要： Novel radioactive estradienes labelled with iodine of the formula ##STR1## in the form of their syn or anti isomers or mixtures thereof wherein the wavy line indicates anti or syn position, R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 1 to 12 carbon atoms and R.sub.1 is the residue of an amino acid R.sub.1 NH.sub.2 possessing an iodine acceptor group or a derivative thereof labelled with iodine .sup.125 or .sup.131 and their preparation and novel intermediates, antigens prepared from the compounds of formula I and bovine seric albumin or human seric albumin and their preparation and their use for the preparation of antibodies.

    摘要翻译： 以其顺式或反式异构体或其混合物的形式用碘标记的新型放射性碘化物，其中波浪线表示抗或顺式位置，R选自氢，1至6的烷基 碳原子和碳原子数为1〜12的有机羧酸的酰基，R 1为具有用碘125或131标记的碘受体基团或其衍生物的氨基酸R 1 NH 2的残基及其制备和新型中间体，由 式I化合物和牛血清白蛋白或人血清白蛋白及其制备及其用于制备抗体的用途。

    Novel radioactive estratrienes
    2.
    发明授权
    Novel radioactive estratrienes 失效
    新型放射性三异构体

    公开(公告)号：US4632820A

    公开(公告)日：1986-12-30

    申请号：US560184

    申请日：1983-12-12

    申请人： Alain Jouquey ,  Gaetan Touyer ,  Jean Salmon ,  Michel Mouren

    发明人： Alain Jouquey ,  Gaetan Touyer ,  Jean Salmon ,  Michel Mouren

    IPC分类号： C07J1/00 ,  C07J41/00 ,  G01N33/534 ,  A61K49/00 ,  A61K43/00

    CPC分类号： C07J41/0016 ,  G01N33/534

    摘要： Novel radioactive .DELTA..sup.4,9,11 -estratrienes marked with iodine 125 or 131 having the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 2 to 12 carbon atoms, R.sub.1 is the reminder of an amino acid of the formula R.sub.1 NH.sub.2 or a derivative thereof being marked with iodine 125 or 131 and the wavy lines indicate the --OR is in the .alpha.- or .beta.-position and the oximido group is in the syn or anti position, a process and intermediates for their preparation, antigens prepared therefrom and use thereof to prepare antibodies.

    摘要翻译： 用碘125或131标记的新型放射性DELTA 4,9,11-雌三醇，其具有式I图1其中R选自氢，1至6个碳原子的烷基和2位有机羧酸的酰基 至12个碳原子，R1是式R1NH2的氨基酸或其衍生物用碘125或131标记的波形，波浪线表示-OR为α或β-位，肟基为 在syn或反位置，其制备方法和中间体，由其制备的抗原及其制备抗体的用途。

    Novel steroids
    4.
    发明授权
    Novel steroids 失效
    新型类固醇

    公开(公告)号：US4191697A

    公开(公告)日：1980-03-04

    申请号：US915601

    申请日：1978-06-15

    申请人： Alain Jouquey ,  Jean-Pierre Raynaud ,  Jean Salmon

    发明人： Alain Jouquey ,  Jean-Pierre Raynaud ,  Jean Salmon

    IPC分类号： A61K51/00 ,  C07J1/00 ,  C07J17/00 ,  C07J51/00 ,  G01N33/534 ,  G01N33/60

    CPC分类号： C07J1/007

    摘要： Novel .DELTA..sup.1,3,5(10),6 -estratetraenes of the formula ##STR1## R is selected from the group consisting of hydrogen, acyl of an alkanoic acid of 1 to 5 carbon atoms, optionally substituted benzoyl, tetrahydropyranyl, trityl and trimethylsilyl and R.sub.1 is selected from the group consisting of acyl of an alkanoic acid of 1 to 5 carbon atoms, optionally substituted benzoyl, tetrahydropyranyl, trityl and trimethylsilyl, novel intermediates therefore, process for the preparation of estradiols marked with a tritium atom and the novel tritiated estradiols which are useful to the study and dosage of specific receptors of estrogen.

    摘要翻译： 新型的DELTA 1,3,5（10），式VI的6-季四烯选自氢，1至5个碳原子的链烷酸的酰基，任选取代的苯甲酰基，四氢吡喃基，三苯甲基和三 三甲基甲硅烷基，R 1选自由1-5个碳原子的链烷酸酰基，任选取代的苯甲酰基，四氢吡喃基，三苯甲基和三甲基甲硅烷基组成的组，因此，新的中间体是制备标有氚原子的雌二醇的方法， 氚化雌二醇可用于雌激素特异性受体的研究和剂量。

    Device for adjusting a moving position of a headlight, a headlight including the device, and a method of installing the device
    5.
    发明授权
    Device for adjusting a moving position of a headlight, a headlight including the device, and a method of installing the device 失效
    用于调整头灯的移动位置的装置，包括该装置的头灯以及安装该装置的方法

    公开(公告)号：US5428519A

    公开(公告)日：1995-06-27

    申请号：US94252

    申请日：1993-07-20

    申请人： Jean Salmon ,  Jean-Pierre Loiselet ,  Vincent Demarcq

    发明人： Jean Salmon ,  Jean-Pierre Loiselet ,  Vincent Demarcq

    IPC分类号： B60Q1/06 ,  B60Q1/068 ,  F21S8/10 ,  F21V14/04

    CPC分类号： B60Q1/0683 ,  B60Q2200/32 ,  Y10T403/32311 ,  Y10T403/32795 ,  Y10T403/60

    摘要： An adjustment device for adjusting a moving portion of a motor vehicle headlight relative to a fixed portion, in particular a reflector relative to an intermediate part of the headlight, the device being of the type comprising a screw that includes a ball member received in a seat connected to one of the portions and a thread engaging in tapping connected to the other portion, wherein the ball seat and the tapping are respectively provided on two elements each including assembly means enabling it to be assembled to corresponding assembly means provided on said respective portions merely by relative displacement.

    摘要翻译： 一种用于调节机动车辆前灯相对于固定部分的移动部分的调节装置，特别是相对于前灯的中间部分的反射器，所述装置的类型包括螺钉，所述螺钉包括容纳在座椅中的球件 连接到这些部分中的一个部分，以及接合与另一部分连接的螺纹的螺纹，其中球座和攻丝分别设置在两个元件上，每个元件包括组装装置，使得其能够组装到仅设置在所述各个部分上的对应的组装装置 通过相对位移。

    Device for the detection of the position of a railway vehicle
    6.
    发明授权
    Device for the detection of the position of a railway vehicle 失效
    用于检测铁路车辆位置的装置

    公开(公告)号：US4274611A

    公开(公告)日：1981-06-23

    申请号：US54818

    申请日：1979-07-05

    申请人： Jean Salmon

    发明人： Jean Salmon

    IPC分类号： B61L3/12 ,  B61L25/02

    CPC分类号： B61L3/121

    摘要： In a train control system wherein emitter beacons are located at predetermined points on the track near to one of the running rails, a device for detecting the position of a vehicle running on the railway track. It comprises into each beacon a radiating vertical-axis coil powered by an alternating current of a given frequency and, on board the vehicle, near to the corresponding rail, a pick-up unit including two pairs of receiver coils the axes of which are horizontal and perpendicular to the running rails. The associated circuits comprise two differential amplifiers connected to at least to two band-pass filters and a multiplier circuit in order to generate a positive signal when and only when the beacon is located between the two pairs of coils and the frequency of the beacon is the central frequency of the filters.

    摘要翻译： 在列车控制系统中，其中发射器信标位于靠近其中一个行驶轨道的轨道上的预定点处，用于检测在铁路轨道上行驶的车辆的位置的装置。 它在每个信标中包括由给定频率的交流电供电的辐射垂直轴线圈，并且在车辆上靠近相应的导轨上，拾取单元包括两对接收器线圈，其轴线是水平的 并垂直于跑道。 相关联的电路包括连接到至少两个带通滤波器的两个差分放大器和乘法器电路，以便当且仅当信标位于两对线圈之间时产生正信号，并且信标的频率为 过滤器的中心频率。