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公开(公告)号:US06905733B2
公开(公告)日:2005-06-14
申请号:US10202224
申请日:2002-07-24
IPC分类号: G01N27/327 , C12N11/04 , C12N11/08 , B05D3/00
摘要: This invention provides a method of irreversibly immobilizing an enzyme into polyurethane coatings. This invention also provides for an enzyme-containing coating having a degree of immobilization of the enzyme of approximately 100%. The synthesis of waterborne polyurethane coatings in the presence of enzyme has enabled the irreversible attachment of the enzyme to the polymeric matrix. The distribution of immobilized enzyme as well as activity retention are homogeneous within the coating. Decreasing ECC hydrophobicity, via the use of a less hydrophobic polyisocyanate prepolymer during polymerization, significantly enhanced the intrinsic activity of the ECC.
摘要翻译: 本发明提供了将酶不可逆地固定在聚氨酯涂层中的方法。 本发明还提供具有大约100%酶固定程度的含酶涂层。 在存在酶的情况下水性聚氨酯涂层的合成使酶能够与聚合物基质不可逆地连接。 固定化酶的分布以及活性保留在涂层内是均匀的。 通过在聚合过程中通过使用较少疏水性的多异氰酸酯预聚物来降低ECC疏水性,显着提高了ECC的内在活性。
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公开(公告)号:US20080108745A1
公开(公告)日:2008-05-08
申请号:US12002841
申请日:2007-12-19
IPC分类号: C08G18/00
CPC分类号: C12N11/08 , C08G18/0866 , C08G18/3278 , C08G18/42 , C08G18/6446 , C08G18/706 , C08G18/798 , C09D175/04 , C12N11/04
摘要: A method of irreversibly immobilizing an enzyme in a polyurethane and an enzyme-containing polyurethane having a degree of immobilization of the enzyme of approximately 100%. The synthesis of waterborne polyurethanes in the presence of enzyme has enabled the irreversible attachment of the enzyme to the polymeric matrix. The distribution of immobilized enzyme as well as activity retention are homogeneous within the polyurethane. Decreasing ECC hydrophobicity, via the use of a less hydrophobic polyisocyanate prepolymer during polymerization, significantly enhanced the intrinsic activity of the ECC.
摘要翻译: 一种不可逆地将酶固定在聚氨酯中的方法和具有约100%酶固定度的含酶聚氨酯。 在存在酶的情况下水性聚氨酯的合成使得酶不可逆连接到聚合物基质上。 固定化酶的分布以及活性保留在聚氨酯中是均匀的。 通过在聚合过程中通过使用较少疏水性的多异氰酸酯预聚物来降低ECC疏水性,显着提高了ECC的内在活性。
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公开(公告)号:US20060011295A1
公开(公告)日:2006-01-19
申请号:US10890873
申请日:2004-07-14
申请人: Karsten Danielmeier , Douglas Wicks , Karen Henderson , Evan Minnich , John McLafferty , Stephanie Strazisar , Kurt Frisch
发明人: Karsten Danielmeier , Douglas Wicks , Karen Henderson , Evan Minnich , John McLafferty , Stephanie Strazisar , Kurt Frisch
IPC分类号: C07C229/34
CPC分类号: C08G18/341 , C07C229/24 , C08G18/3821 , C08G18/6651 , C08G18/6685 , C08G18/792 , Y10T428/31547
摘要: A functional aspartate prepared by A) reacting an aziridine with a Michael-acceptor molecule to form an aziridinyl aspartate, and B) reacting the aziridinyl aspartate with an active hydrogen containing compound to form the functional aspartate. The functional aspartate can be used in adhesive, sealant or coating compositions that also include an isocyanate functional material. The composition can be used in a method of bonding a first substrate to a second substrate that includes applying a coating of the above-identified adhesive composition to at least one surface of the first substrate or the second substrate, and contacting a surface of the first substrate with a surface of the second substrate, where at least on of the contacting surfaces has the coating applied thereto. The composition can also be used to coat substrates.
摘要翻译: 通过A)将氮丙啶与迈克尔受体分子反应以形成天冬氨酸吖丙酯反应制备的功能性天冬氨酸,和B)将天冬氨酸吖丙酯与含活性氢化合物反应以形成功能性天冬氨酸。 功能性天冬氨酸可用于还包括异氰酸酯官能材料的粘合剂,密封剂或涂料组合物。 该组合物可用于将第一基底粘合到第二基底上的方法,该方法包括将上述粘合剂组合物的涂层施加到第一基底或第二基底的至少一个表面,并使第一基底 衬底,其具有第二衬底的表面,其中至少在接触表面上施加有涂层。 该组合物也可用于涂覆底物。
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公开(公告)号:US20050075476A1
公开(公告)日:2005-04-07
申请号:US10678491
申请日:2003-10-03
申请人: Richard Roesler , Douglas Wicks , Terrell Wayt , Brian Long , Karsten Danielmeier , Charles Gambino
发明人: Richard Roesler , Douglas Wicks , Terrell Wayt , Brian Long , Karsten Danielmeier , Charles Gambino
IPC分类号: C07C233/00 , C07C235/10 , C07C269/04 , C07C271/00 , C07C271/20 , C07C271/24 , C08G18/38 , C08G18/79 , C08G69/02 , C09D175/02 , C08G18/00 , C08G2/00
CPC分类号: C07C235/10 , C07C271/20 , C07C271/24 , C07C2601/14 , C08G18/3821 , C08G18/792 , C09D175/02
摘要: The present invention relates to novel aspartates, their method of produciotn and the use of these mono and polyaspartates as reactive components for polyisocyanates in two-component polyurethane coating compositions and for preparing polyurethane prepolymers.
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公开(公告)号:US20050054766A1
公开(公告)日:2005-03-10
申请号:US10850674
申请日:2004-05-21
IPC分类号: C08G18/00 , C08G18/32 , C08G18/42 , C08G18/64 , C08G18/70 , C08G18/79 , C09D175/04 , C12N11/04 , C12N11/08 , B05D3/02 , C08K3/00
CPC分类号: C12N11/08 , C08G18/0866 , C08G18/3278 , C08G18/42 , C08G18/6446 , C08G18/706 , C08G18/798 , C09D175/04 , C12N11/04
摘要: A method of irreversibly immobilizing an enzyme in a polyurethane and an enzyme-containing polyurethane having a degree of immobilization of the enzyme of approximately 100%. The synthesis of waterborne polyurethanes in the presence of enzyme has enabled the irreversible attachment of the enzyme to the polymeric matrix. The distribution of immobilized enzyme as well as activity retention are homogeneous within the polyurethane. Decreasing ECC hydrophobicity, via the use of a less hydrophobic polyisocyanate prepolymer during polymerization, significantly enhanced the intrinsic activity of the ECC.
摘要翻译: 一种不可逆地将酶固定在聚氨酯中的方法和具有约100%酶固定度的含酶聚氨酯。 在存在酶的情况下水性聚氨酯的合成使得酶不可逆连接到聚合物基质上。 固定化酶的分布以及活性保留在聚氨酯中是均匀的。 通过在聚合过程中通过使用较少疏水性的多异氰酸酯预聚物来降低ECC疏水性,显着提高了ECC的内在活性。
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公开(公告)号:US20110196129A1
公开(公告)日:2011-08-11
申请号:US11920456
申请日:2006-05-04
申请人: Chunyong Wu , Jun Li , Douglas Wicks , Sarah Morgan , Robert Allen Smith
发明人: Chunyong Wu , Jun Li , Douglas Wicks , Sarah Morgan , Robert Allen Smith
IPC分类号: C08H1/06
CPC分类号: C07K14/4741 , A61K35/36 , A61L26/0047 , A61L26/008 , A61L27/227 , A61L27/52
摘要: Keratin hydratable absorbents and films are fabricated with simple, repeatable processes. Freeze drying produces a material with instantaneous water absorption to over 20 times its weight in water. Films produced are flexible and uniform with water absorption 7-8 times the original weight.
摘要翻译: 角蛋白可水合的吸收剂和膜通过简单,可重复的方法制造。 冷冻干燥产生一种具有瞬间吸水率至水分重量20倍以上的材料。 生产的薄膜柔软均匀,吸水率为原重量的7-8倍。
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公开(公告)号:US20050059792A1
公开(公告)日:2005-03-17
申请号:US10941579
申请日:2004-09-15
申请人: Richard Roesler , Douglas Wicks , Karen Henderson
发明人: Richard Roesler , Douglas Wicks , Karen Henderson
IPC分类号: C08G63/78 , C08G18/38 , C08G18/46 , C08G18/67 , C08G63/00 , C08G63/52 , C08G65/329 , C08G69/26 , C08G69/46 , C09D175/02 , C08G18/00
CPC分类号: C08G18/4669 , C08G18/3821 , C09D175/02
摘要: The present invention is directed to a method of preparing polyaspartates, polyaspartates so-produced and the use thereof in a coating composition. The process broadly comprises a) transesterifying an α,β-unsaturated ester with a hydroxy functional material, b) reacting the transesterified product with a primary amine-containing compound and c) reacting any remaining primary amine groups with an α,β-unsaturated ester
摘要翻译: 本发明涉及一种制备聚天冬氨酸盐,如此制备的聚天冬氨酸盐及其在涂料组合物中的用途的方法。 该方法广泛地包括a)使α,β-不饱和酯与羟基官能材料酯交换,b)使酯交换产物与含伯胺的化合物反应,和c)使任何剩余的伯胺基团与α,β-不饱和酯
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公开(公告)号:US20050059791A1
公开(公告)日:2005-03-17
申请号:US10664194
申请日:2003-09-17
申请人: Richard Roesler , Douglas Wicks , Karen Henderson
发明人: Richard Roesler , Douglas Wicks , Karen Henderson
IPC分类号: C08G63/78 , C08G18/38 , C08G18/46 , C08G18/67 , C08G63/00 , C08G63/52 , C08G65/329 , C08G69/26 , C08G69/46 , C09D175/02 , C08G18/00
CPC分类号: C08G18/4669 , C08G18/3821 , C09D175/02
摘要: The present invention is directed to a method of preparing polyaspartates, polyaspartates so-produced and the use thereof in a coating composition. The process broadly comprises a) transesterifying an α, β-unsaturated ester with a hydroxy functional material, b) reacting the transesterified product with a primary amine-containing compound and c) reacting any remaining primary amine groups with an α,β-unsaturated ester
摘要翻译: 本发明涉及一种制备聚天冬氨酸盐,如此制备的聚天冬氨酸盐及其在涂料组合物中的用途的方法。 该方法广泛地包括a)使α,β-不饱和酯与羟基官能材料酯交换,b)使酯交换产物与含伯胺的化合物反应,和c)使任何剩余的伯胺基团与α,β-不饱和酯
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