摘要:
This invention relates to crystalline structures of the topoisomerase I and their use in designing new anti-cancer agents anti-viral agents and anti-microbial agents.
摘要:
A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
摘要:
A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
摘要:
A coupling system can utilize a first receptacle and a second receptacle to couple syringes together. Syringes can be used to mix viscous material and/or dispense the viscous material. Furthermore, a kit can be provided that contains parts used in mixing and/or dispensing viscous material.
摘要:
Disclosed is a system and a method for depositing crystallization observations into a relational database. The system includes a computer, microscope, and a headset having a microphone and headphones. Crystallization observations are deposited into the database by verbal commands. Verbal commands also drive the crystallization apparatus plates to position the apparatus wells within the microscope field of vision. The system is integrated with a software application which enables the user to build the trials, matrices, solutions, and macromolecules to be used in the crystallization trials. The user is guided through the crystallization trial setup by a multitude of managers and builders of the software application. The software application also provides numerous tools to query the database and display results in a multitude of formats.
摘要:
Devices, systems and methods for receiving, recording, and/or displaying information related to physical exercise are disclosed herein. In one embodiment, an instrumented weight pin for use with a stacked weight exercise machine includes a shaft portion extending outwardly from a handle portion. In this embodiment, the shaft portion is configured to be removably positioned adjacent to one or more weights of the exercise machine to selectively engage the one or more weights during use of the exercise machine. The weight pin can further include a load sensor and/or an accelerometer. The load sensor and/or the accelerometer can provide information associated with an exercise set to a data storage device carried by the weight pin. The data storage device can be operably coupled to a user computer or other display device so that information relating to the exercise set can be displayed for viewing by the user.
摘要:
In one aspect, the present invention provides crystallization solutions useful for crystallizing proteins and other molecules, especially macromolecules. In a presently preferred embodiment, the crystallization solutions of the invention are combined as four crystallization solution sets. Each of the four crystallization solution sets includes forty eight different crystallization solutions. Each individual crystallization solution includes a precipitant and a buffer, and optionally includes at least one additive. In another aspect, the present invention provides kits including a plurality of crystallization solutions of the present invention and at least one crystallization plate that preferably includes a plurality of reservoirs. Preferably the crystallization solutions are disposed within the reservoirs of the crystallization plates.
摘要:
Devices, systems and methods for receiving, recording, and/or displaying information related to physical exercise are disclosed herein. In one embodiment, an instrumented weight pin for use with a stacked weight exercise machine includes a shaft portion extending outwardly from a handle portion. In this embodiment, the shaft portion is configured to be removably positioned adjacent to one or more weights of the exercise machine to selectively engage the one or more weights during use of the exercise machine. The weight pin can further include a load sensor and/or an accelerometer. The load sensor and/or the accelerometer can provide information associated with an exercise set to a data storage device carried by the weight pin. The data storage device can be operably coupled to a user computer or other display device so that information relating to the exercise set can be displayed for viewing by the user.
摘要:
Devices, systems and methods for receiving, recording, and/or displaying information related to physical exercise are disclosed herein. In one embodiment, an instrumented weight pin for use with a stacked weight exercise machine includes a shaft portion extending outwardly from a handle portion. In this embodiment, the shaft portion is configured to be removably positioned adjacent to one or more weights of the exercise machine to selectively engage the one or more weights during use of the exercise machine. The weight pin can further include a load sensor and/or an accelerometer. The load sensor and/or the accelerometer can provide information associated with an exercise set to a data storage device carried by the weight pin. The data storage device can be operably coupled to a user computer or other display device so that information relating to the exercise set can be displayed for viewing by the user.
摘要:
The present invention provides a crystallization unit including a solvent reservoir in gaseous communication with a plurality of chambers. Preferably, a plurality of crystallization units are arrayed in the form of a crystallization tray. A first preferred embodiment of the present invention provides a crystallization tray 10 including a rectangular array of crystallization units 26. Each crystallization unit includes a central reservoir 28 and four drop chambers 32 arranged in a cruciform configuration around central reservoir 28. Each drop chamber 32 is connected to central reservoir 28 by a diffusion channel 30. Each drop chamber 32 also includes a shoulder which is capable of supporting a cover slip from which a drop of solution, containing the substance to be crystallized, can be suspended. A second preferred embodiment of the present invention is identical to the first preferred embodiment except that central reservoir 28 is divided into four equal sections by dividers extending vertically from the bottom of central reservoir 28.