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公开(公告)号:US07507873B2
公开(公告)日:2009-03-24
申请号:US11649543
申请日:2007-01-04
IPC分类号: A01K67/027 , A01K67/00 , A01K67/033
CPC分类号: C07K16/02 , A01K67/0275 , A01K2217/05 , A01K2227/30 , A01K2267/01 , C07K16/2809 , C07K16/44 , C07K2317/21 , C07K2317/732 , C07K2317/734 , C07K2319/30 , C12N15/8509 , C12N2800/204 , C12N2800/30 , C12N2830/008
摘要: Transgenic avians having a recombinant ovomucoid gene expression controlling region operably linked to one or more useful amino acid coding sequences.
摘要翻译: 具有与一个或多个有用的氨基酸编码序列可操作地连接的重组卵巢粘蛋白基因表达控制区的转基因鸟类。
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公开(公告)号:US20090182130A1
公开(公告)日:2009-07-16
申请号:US12313064
申请日:2008-11-17
IPC分类号: C07K1/14
CPC分类号: C07K16/02 , A01K67/0275 , A01K2217/05 , A01K2227/30 , A01K2267/01 , C07K16/2809 , C07K16/44 , C07K2317/21 , C07K2317/732 , C07K2317/734 , C07K2319/30 , C12N15/8509 , C12N2800/204 , C12N2800/30 , C12N2830/008
摘要: Methods of producing protein using a recombinant ovomucoid gene expression controlling region operably linked to one or more useful amino acid coding sequences.
摘要翻译: 使用与一个或多个有用的氨基酸编码序列有效连接的重组卵巢粘蛋白基因表达控制区产生蛋白质的方法。
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公开(公告)号:US07294507B2
公开(公告)日:2007-11-13
申请号:US10856218
申请日:2004-05-28
IPC分类号: C12N15/00
CPC分类号: A01K67/0275 , A01K2217/052 , A01K2217/206 , A01K2227/30 , A01K2267/01 , C07K2317/732 , C07K2317/734 , C12N15/8509 , C12N2800/204 , C12N2830/008 , C12N2830/90
摘要: The present invention includes nucleic acid molecules comprising an artificial chromosome and an avian ovomucoid gene expression controlling region operably linked to the coding sequence of a useful polypeptide.
摘要翻译: 本发明包括核酸分子,其包含可操作地连接到有用多肽的编码序列的人造染色体和禽类卵巢粘蛋白基因表达控制区。
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公开(公告)号:US07812215B2
公开(公告)日:2010-10-12
申请号:US12313064
申请日:2008-11-17
IPC分类号: C12P21/00 , A01K67/027
CPC分类号: C07K16/02 , A01K67/0275 , A01K2217/05 , A01K2227/30 , A01K2267/01 , C07K16/2809 , C07K16/44 , C07K2317/21 , C07K2317/732 , C07K2317/734 , C07K2319/30 , C12N15/8509 , C12N2800/204 , C12N2800/30 , C12N2830/008
摘要: Methods of producing protein using a recombinant ovomucoid gene expression controlling region operably linked to one or more useful amino acid coding sequences.
摘要翻译: 使用与一个或多个有用的氨基酸编码序列有效连接的重组卵巢粘蛋白基因表达控制区产生蛋白质的方法。
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公开(公告)号:US07335761B2
公开(公告)日:2008-02-26
申请号:US11047184
申请日:2005-01-31
CPC分类号: C07K16/02 , A01K67/0275 , A01K2217/05 , A01K2227/30 , A01K2267/01 , C07K16/2809 , C07K16/44 , C07K2317/21 , C07K2317/732 , C07K2317/734 , C07K2319/30 , C12N15/8509 , C12N2800/204 , C12N2800/30 , C12N2830/008
摘要: The present invention includes avian ovomucoid gene expression controlling regions which may be operably linked to one or more useful amino acid coding sequences.
摘要翻译: 本发明包括可以与一个或多个有用的氨基酸编码序列可操作地连接的鸟类卵类粘蛋白基因表达控制区。
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公开(公告)号:US20090188002A1
公开(公告)日:2009-07-23
申请号:US12316591
申请日:2008-12-12
IPC分类号: A01K67/027 , C12N15/85
CPC分类号: C12N9/22 , A01K67/0275 , A01K2217/05 , A01K2227/30 , A01K2227/40 , A01K2267/01 , C12N15/8509 , C12N15/873 , C12N2800/20 , C12N2800/204 , C12N2800/206 , C12N2830/00 , C12N2830/40 , C12N2830/90 , C12N2840/203
摘要: The invention includes avians containing an artificial chromosome in their genome and methods of making the avians.
摘要翻译: 本发明包括在其基因组中含有人造染色体的鸟类和制作鸟类的方法。
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公开(公告)号:US07432103B2
公开(公告)日:2008-10-07
申请号:US12012387
申请日:2008-02-01
申请人: Jeffrey C. Rapp , Stephen H. Parker , Markley C. Leavitt , Dawn M. Eberhardt , Leandro Christmann , Alex J. Harvey
发明人: Jeffrey C. Rapp , Stephen H. Parker , Markley C. Leavitt , Dawn M. Eberhardt , Leandro Christmann , Alex J. Harvey
CPC分类号: C12P21/02
摘要: The present invention relates to cells that can be passaged in culture and can be used for, among other things, promoter assays and the production of heterologous proteins.
摘要翻译: 本发明涉及可以在培养物中传代的细胞,并且可以用于促进剂测定和异源蛋白质的生产。
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公开(公告)号:US20100083389A1
公开(公告)日:2010-04-01
申请号:US12387434
申请日:2009-05-01
IPC分类号: A01K67/027 , C12N15/09 , C12N15/13
CPC分类号: C07K16/00 , A01K67/0275 , A01K2207/15 , A01K2217/00 , A01K2227/30 , A01K2267/01 , C07K2317/20 , C07K2317/23 , C12N15/8509 , C12N2799/027 , C12N2800/30 , C12N2830/008 , C12N2830/15 , C12N2830/46 , C12N2830/90 , C12N2840/203
摘要: The invention includes methods of making transgenic avians by introducing a nucleic acid sequence into the genome of an avian embryo wherein the nucleic acid sequence comprises a nucleotide sequence encoding a heterologous protein, developing the avian embryo to hatch, developing the hatched chick to sexual maturity and obtaining offspring from the sexually mature hatched chick which produce egg white containing the heterologous protein.
摘要翻译: 本发明包括通过将核酸序列引入禽胚胎的基因组中来制备转基因鸟类的方法,其中所述核酸序列包含编码异源蛋白质的核苷酸序列,开发禽类胚胎孵化,将孵出的雏鸡发育成性成熟, 从产生含有异源蛋白质的蛋白的性成熟孵出的小鸡获得后代。
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公开(公告)号:US20080145861A1
公开(公告)日:2008-06-19
申请号:US12012387
申请日:2008-02-01
申请人: Jeffrey C. Rapp , Stephen H. Parker , Markley C. Leavitt , Dawn M. Eberhardt , Leandro Christmann , Alex J. Harvey
发明人: Jeffrey C. Rapp , Stephen H. Parker , Markley C. Leavitt , Dawn M. Eberhardt , Leandro Christmann , Alex J. Harvey
CPC分类号: C12P21/02
摘要: The present invention relates to cells that can be passaged in culture and can be used for, among other things, promoter assays and the production of heterologous proteins.
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公开(公告)号:US07351582B2
公开(公告)日:2008-04-01
申请号:US11454399
申请日:2006-06-16
申请人: Jeffrey C. Rapp , Stephen H. Parker , Markley C. Leavitt , Dawn M. Eberhardt , Leandro Christmann , Alex J. Harvey
发明人: Jeffrey C. Rapp , Stephen H. Parker , Markley C. Leavitt , Dawn M. Eberhardt , Leandro Christmann , Alex J. Harvey
CPC分类号: C12P21/02
摘要: The present invention relates to cells that can be passaged in culture and can be used for, among other things, promoter assays and the production of heterologous proteins.
摘要翻译: 本发明涉及可以在培养物中传代的细胞,并且可以用于促进剂测定和异源蛋白质的生产。
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