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公开(公告)号：US12129342B2
公开(公告)日：2024-10-29
申请号：US17976303
申请日：2022-10-28
摘要： Disclosed herein are processes for ethanol production from a lignocellulosic feedstock. These processes provide DMR of lignocellulosic biomass comprising two-stage deacetylation followed by mechanical refining so as to increase fermentable sugar yield while reducing hydrolytic enzyme loading requirements.
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公开(公告)号：US10036051B2
公开(公告)日：2018-07-31
申请号：US15594031
申请日：2017-05-12
发明人： William S. Adney , Gregg T. Beckham , Eric Jarvis , Michael E. Himmel , Stephen R. Decker , Jeffrey G. Linger , Kara Podkaminer , John O. Baker , Larry Taylor, II , Qi Xu , Arjun Singh
CPC分类号： C12P19/14 , C10L1/02 , C10L2290/26 , C12N9/2437 , C12P7/10 , C12P7/14 , C12P19/02 , C12Y302/01004 , C12Y302/01021 , Y02E50/16 , Y02E50/343
摘要： Nucleic acid sequences encoding chimeric polypeptides that exhibit enhanced cellulase activities are disclosed herein. These nucleic acids may be expressed in hosts such as fungi, which in turn may be cultured to produce chimeric polypeptides. Also disclosed are chimeric polypeptides and their use in the degradation of cellulosic materials.
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公开(公告)号：US09249432B2
公开(公告)日：2016-02-02
申请号：US13941754
申请日：2013-07-15
发明人： Roman Brunecky , Michael E. Himmel
CPC分类号： C12P7/14 , C12N9/2437 , C12N9/2445 , C12P19/02 , C12P19/14 , Y02E50/16
摘要： Disclosed herein are enzymes and combinations of the enzymes useful for the hydrolysis of cellulose and the conversion of biomass. Methods of degrading cellulose and biomass using enzymes and cocktails of enzymes are also disclosed.
摘要翻译： 本文公开了可用于水解纤维素的酶和酶的组合以及生物质的转化。 还公开了使用酶和酶的鸡尾酒降解纤维素和生物质的方法。
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公开(公告)号：US10793699B2
公开(公告)日：2020-10-06
申请号：US15902429
申请日：2018-02-22
摘要： Disclosed herein are a cellulose particle and a binder, where the cellulose particle has a cellulose core and a surface group, and the binder interacts with the surface group to form a composite.
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公开(公告)号：US10577633B2
公开(公告)日：2020-03-03
申请号：US15467340
申请日：2017-03-23
IPC分类号： C12P7/18 , C12N11/00 , C12N9/04 , C12N9/02 , C12N9/10 , C12N15/62 , C12N11/18 , C07K14/195 , C12N11/06 , C12P7/42
摘要： Polypeptide scaffolds comprising enzymatic proteins are provided. The enzymatic polypeptide scaffolds comprise heterologous enzymes to form a heterologous metabolic pathway, and can be targeted to a substrate through a surface anchoring domain. The enzymatic polypeptide scaffolds leverage the high specificity and affinity protein/protein interaction between the cohesins and dockerins of microorganismal cellulosomes to form custom enzymatic arrays.
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公开(公告)号：US08993276B2
公开(公告)日：2015-03-31
申请号：US13940936
申请日：2013-07-12
发明人： Qi Xu , John O. Baker , Michael E. Himmel
IPC分类号： C12P19/14 , C12N9/96 , C12N9/14 , C12N9/24 , C12P21/06 , C12P19/34 , C12N15/00 , C12N1/20 , C07H21/04 , C07K1/00 , C12N9/42
CPC分类号： C12P19/14 , C12N9/2437
摘要： Nucleic acid molecules encoding chimeric cellulase polypeptides that exhibit improved cellulase activities are disclosed herein. The chimeric cellulase polypeptides encoded by these nucleic acids and methods to produce the cellulases are also described, along with methods of using chimeric cellulases for the conversion of cellulose to sugars such as glucose.
摘要翻译： 本文公开了编码显示改善的纤维素酶活性的嵌合纤维素酶多肽的核酸分子。 还描述了由这些核酸编码的嵌合纤维素酶多肽和产生纤维素酶的方法，以及使用嵌合纤维素酶将纤维素转化为糖如葡萄糖的方法。
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公开(公告)号：US11091782B2
公开(公告)日：2021-08-17
申请号：US16173910
申请日：2018-10-29
发明人： Min Zhang , Yat-Chen Chou , Mary Ann Franden , Michael E. Himmel
摘要： Non-naturally occurring Zymomonas strains useful for the production of 2,3-butanediol are provided.
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公开(公告)号：US12006421B2
公开(公告)日：2024-06-11
申请号：US16926263
申请日：2020-07-10
CPC分类号： C08L1/02 , C08K5/098 , C08K5/19 , C08L2203/12
摘要： Disclosed herein are a cellulose particle and a binder, where the cellulose particle has a cellulose core and a surface group, and the binder interacts with the surface group to form a composite.
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公开(公告)号：US10329548B2
公开(公告)日：2019-06-25
申请号：US16007797
申请日：2018-06-13
发明人： Venkataramanan Subramanian , Michael E. Himmel , Stephen Robert Decker , Gregg Tyler Beckham , Jeffrey G. Linger
摘要： Disclosed herein are chimeric Cel7A polypeptides useful for producing biofuels from lignocellulosic biomass.
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公开(公告)号：US20180355333A1
公开(公告)日：2018-12-13
申请号：US16007797
申请日：2018-06-13
发明人： Venkataramanan Subramanian , Michael E. Himmel , Stephen Robert Decker , Gregg Tyler Beckham , Jeffrey G. Linger
IPC分类号： C12N9/24
CPC分类号： C12N9/2402 , C12Y302/01091
摘要： Disclosed herein are chimeric Cel7A polypeptides useful for producing biofuels from lignocellulosic biomass.
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