Homologous Amds Genes as Selectable Marker
    4.
    发明申请
    Homologous Amds Genes as Selectable Marker 审中-公开
    同源Amds基因作为可选标记

    公开(公告)号:US20080070277A1

    公开(公告)日:2008-03-20

    申请号:US11664585

    申请日:2005-10-17

    CPC分类号: C12N9/80

    摘要: The present invention relates to novel functional amdS genes from A. niger that can be used as dominant and bi-directional selection marker gene in the transformation of organisms. The present invention further relates to the production of a compound of interest in a fungal host cell transformed with the amdS genes of the invention. Preferred fungal host cells are filamentous fungal cells. The amdS genes of the invention provide means for identification of functional homologues in other Aspergillus species.

    摘要翻译: 本发明涉及来自黑曲霉的新型功能性amdS基因,其可用作生物体转化中的显性和双向选择标记基因。 本发明还涉及在用本发明的amdS基因转化的真菌宿主细胞中生产目的化合物。 优选的真菌宿主细胞是丝状真菌细胞。 本发明的amdS基因提供用于鉴定其他曲霉属物种中功能同系物的方法。