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1.发明授权Method for producing microporous elements, the microporous elements thus produced and uses thereof 有权微孔元件的制造方法，由此制造的微孔元件及其用途公开(公告)号：US06451260B1
公开(公告)日：2002-09-17
申请号：US09242786
申请日：1999-03-09
IPC分类号： G01N1506
CPC分类号： B01D67/0002 , B01D15/22 , B01D15/325 , B01D15/327 , B01D15/361 , B01D15/3804 , B01D61/00 , B01D61/18 , B01D67/0006 , B01D67/0018 , B01D69/10 , B01D69/141 , B01D71/08 , B01D71/38 , B01D2239/0471 , B01D2323/08 , B01D2323/12 , B01D2325/36 , B01J20/22 , B01J20/28023 , B01J20/28026 , B01J20/28033 , B01J20/28045 , B01J20/2808 , B01J20/281 , B01J20/3242 , B01J2220/54 , B01J2220/64 , B01L3/0275 , B01L2300/0681 , B01L2300/069 , C12Q1/6806 , G01N1/405 , G01N15/0826 , G01N30/48 , G01N30/6004 , G01N30/6052 , G01N30/6065 , G01N33/54366 , G01N2015/084 , G01N2015/0866 , G01N2500/00 , C12Q2565/137
摘要： Described are novel methods for producing microporous elements and microporous elements obtainable by such methods. Provided are also microporous elements including solid microparticles, which preferably modify the adsorptive properties of the microporous element. Described are also microporous elements which are linked to a support and/or a retainer as well as methods for their production. Filter elements comprising the above-described microporous elements are also provided. Furthermore, kits, diagnostic and pharmaceutical compositions comprising the aforementioned microporous or filter elements are described. Furthermore, uses of the aforementioned microporous and filter elements in microfiltration, chromatography, adsorption/immobilization of organic and inorganic compounds as well as for the preparation and/or detection of such compounds are disclosed.
摘要翻译： 描述了用于制备可通过这种方法获得的微孔元件和微孔元件的新方法。 还提供了包括固体微粒的微孔元件，其优选地改变微孔元件的吸附性能。 还描述了与支撑件和/或保持器连接的微孔元件以及它们的制造方法。 还提供了包括上述微孔元件的滤芯。 此外，描述了包含上述微孔或过滤元件的试剂盒，诊断和药物组合物。 此外，公开了上述微孔和过滤元件在微滤，色谱法，有机和无机化合物的吸附/固定以及用于制备和/或检测这些化合物的用途。
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公开(公告)号：US07183002B2
公开(公告)日：2007-02-27
申请号：US10239112
申请日：2001-03-22
申请人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
CPC分类号： B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要： Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use of identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译： 描述了多孔，铁或铁磁性玻璃颗粒，其在合适的条件下选择性地结合感兴趣的分子，特别是核酸分子。 还描述了制备多孔，铁或铁磁性玻璃颗粒的方法及其鉴定或分离感兴趣的分子的用途。 还提供了包含多孔，铁或铁磁性玻璃颗粒的试剂盒。
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公开(公告)号：US20070080316A1
公开(公告)日：2007-04-12
申请号：US11635304
申请日：2006-12-07
申请人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
CPC分类号： B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要： Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译： 描述了多孔，铁或铁磁性玻璃颗粒，其在合适的条件下选择性地结合感兴趣的分子，特别是核酸分子。 还描述了制备多孔，铁或铁磁性玻璃颗粒的方法及其用于鉴定或分离目的分子的用途。 还提供了包含多孔，铁或铁磁性玻璃颗粒的试剂盒。
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公开(公告)号：US08202427B2
公开(公告)日：2012-06-19
申请号：US13034217
申请日：2011-02-24
申请人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
IPC分类号： B01D11/00
CPC分类号： B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要： Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules; under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译： 描述了多孔，铁或铁磁性玻璃颗粒，其选择性地结合感兴趣的分子，特别是核酸分子; 在适当的条件下。 还描述了制备多孔，铁或铁磁性玻璃颗粒的方法及其用于鉴定或分离目的分子的用途。 还提供了包含多孔，铁或铁磁性玻璃颗粒的试剂盒。
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5.发明申请公开(公告)号：US20110186524A1
公开(公告)日：2011-08-04
申请号：US13034217
申请日：2011-02-24
申请人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
CPC分类号： B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要： Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules; under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译： 描述了多孔，铁或铁磁性玻璃颗粒，其选择性地结合感兴趣的分子，特别是核酸分子; 在适当的条件下。 还描述了制备多孔，铁或铁磁性玻璃颗粒的方法及其用于鉴定或分离目的分子的用途。 还提供了包含多孔，铁或铁磁性玻璃颗粒的试剂盒。
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公开(公告)号：US07922917B2
公开(公告)日：2011-04-12
申请号：US11635304
申请日：2006-12-07
申请人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人： Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
IPC分类号： C01G49/02
CPC分类号： B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要： Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译： 描述了多孔，铁或铁磁性玻璃颗粒，其在合适的条件下选择性地结合感兴趣的分子，特别是核酸分子。 还描述了制备多孔，铁或铁磁性玻璃颗粒的方法及其用于鉴定或分离目的分子的用途。 还提供了包含多孔，铁或铁磁性玻璃颗粒的试剂盒。
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公开(公告)号：US07683035B1
公开(公告)日：2010-03-23
申请号：US09510534
申请日：2000-02-22
申请人： Christoph Erbacher , Helge Bastian , Ralf Wyrich , Uwe Oelmüller , Thomas Manz
发明人： Christoph Erbacher , Helge Bastian , Ralf Wyrich , Uwe Oelmüller , Thomas Manz
CPC分类号： C12N15/1003 , Y10T436/2525
摘要： The present invention relates to a method of stabilizing and/or isolating nucleic acids, wherein a biological sample containing nucleic acids is contacted with a cationic compound. The invention also relates to said cationic compound per se and to the use of said cationic compound in stabilizing and/or isolating nucleic acids. Furthermore, the invention relates to pharmaceutical compositions, diagnostic compositions, and to compositions used in research, which include cationic compounds or a complex being formed upon contact of said cationic compound with a nucleic acid.
摘要翻译： 本发明涉及一种稳定和/或分离核酸的方法，其中含有核酸的生物样品与阳离子化合物接触。 本发明还涉及所述阳离子化合物本身以及所述阳离子化合物在稳定和/或分离核酸中的用途。 此外，本发明涉及药物组合物，诊断组合物和用于研究的组合物，其包括阳离子化合物或在所述阳离子化合物与核酸接触时形成的络合物。
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公开(公告)号：US5843312A
公开(公告)日：1998-12-01
申请号：US702659
申请日：1996-10-23
申请人： Thomas Manz , Jochen Tittgen
发明人： Thomas Manz , Jochen Tittgen
CPC分类号： B01D15/08 , B01J20/28004 , B01J20/28083 , B01J20/286 , B01J20/3204 , B01J20/3219 , B01J20/3259 , B01D15/361 , B01J2220/54 , B01J2220/58 , B01J2220/64
摘要： A chromatography material is described for separation of nucleic acid mixtures in which a support is converted with a silanization reagent, in which the silanization reagent has a reactive group converted with silanization reagent, in which the silanization reagent has a reactive group converted with an alkyl- or dialkylamine, or contains a reactive group that can be converted with an alkyl- or dialkylamine, which is then reacted with the alkyl- or dialkylamine.
摘要翻译： PCT No.PCT / EP95 / 00434 371日期：1996年10月23日 102（e）日期1996年10月23日PCT 1995年2月7日提交PCT公布。 公开号WO95 / 22053 日期1995年8月17日描述了色谱材料用于分离其中载体用硅烷化试剂转化的核酸混合物，其中硅烷化试剂具有用硅烷化试剂转化的反应性基团，其中硅烷化试剂具有反应性基团 用烷基或二烷基胺转化，或含有可与烷基 - 或二烷基胺转化的反应性基团，然后与烷基 - 或二烷基胺反应。
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