利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

30 条记录 (耗时 0.05 秒)

    Cyanopyrroles
    6.
    发明申请
    Cyanopyrroles 有权
    青色

    公开(公告)号：US20050256110A1

    公开(公告)日：2005-11-17

    申请号：US11184313

    申请日：2005-07-19

    申请人： Mark Collins ,  Valerie Mackner ,  Jay Wrobel ,  Lin Zhi ,  Todd Jones ,  James Edwards ,  Christopher Tegley

    发明人： Mark Collins ,  Valerie Mackner ,  Jay Wrobel ,  Lin Zhi ,  Todd Jones ,  James Edwards ,  Christopher Tegley

    IPC分类号： C07D403/04 ,  A61K31/40 ,  A61K31/403 ,  A61K31/404 ,  A61K31/405 ,  A61K31/536 ,  A61K31/5415 ,  A61P5/34 ,  A61P13/08 ,  A61P15/00 ,  A61P15/14 ,  A61P15/16 ,  A61P15/18 ,  A61P35/00 ,  A61P43/00 ,  C07D413/04

    CPC分类号： C07D403/04 ,  A61K31/405 ,  A61K31/5415 ,  C07D413/04

    摘要： This invention provides a progesterone receptor antagonist of formula 1 having the structure wherein, T is O, S, or absent; R1, and R2 are each, independently, hydrogen, alkyl, substituted alkyl; or R1 and R2 are taken together form a ring and together contain —CH2(CH2)nCH2—, —CH2CH2CMe2CH2CH2—, —O(CH2)pCH2—, —O(CH2)qO—, —CH2CH2OCH2CH2—, or —CH2CH2NR7CH2CH2—; n=1-5; p=1-4; q=1-4; R3 is hydrogen, OH, NH2, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, or CORA; RA is hydrogen, alkyl, substituted alkyl, alkoxy, substituted alkoxy, aminoalkyl, or substituted aminoalkyl; R4 is hydrogen, halogen, CN, NH2, alkyl, substituted alkyl, alkoxy, substituted alkoxy, aminoalkyl, or substituted aminoalkyl; R5 is hydrogen, alkyl, or substituted alkyl; R6 is hydrogen, alkyl, substituted alkyl, or CORB; RB is hydrogen, alkyl, substituted alkyl, alkoxy, substituted alkoxy, aminoalkyl, or substituted aminoalkyl; R7 is hydrogen or alkyl; or a pharmaceutically acceptable salt thereof.

    摘要翻译： 本发明提供具有以下结构的式1的孕酮受体拮抗剂，其中T为O，S或不存在; R 1，R 2和R 2各自独立地为氢，烷基，取代的烷基; 或R 1和R 2一起形成环，并且一起含有-CH 2（CH 2）2 CH 2 CH 2 - ， - CH 2 CH 2 CH 2 CH 2 N 2 CH 2 2 CH 2 - ， - O（CH 2）2 CH 2 - ， - （CH 2 CH 2） O（CH 2 CH 2）q O - ， - CH 2 CH 2 OCH 2 - / SUB CH 2，或CH 2 CH 2，NR 7，CH 2，CH 2， CH 2 - ; n = 1-5; p = 1-4; q = 1-4; R 3是氢，OH，NH 2，烷基，取代的烷基，烯基，取代的烯基，炔基，取代的炔基或COR A。 R A是氢，烷基，取代的烷基，烷氧基，取代的烷氧基，氨基烷基或取代的氨基烷基; R 4是氢，卤素，CN，NH 2，烷基，取代的烷基，烷氧基，取代的烷氧基，氨基烷基或取代的氨基烷基; R 5是氢，烷基或取代的烷基; R 6是氢，烷基，取代的烷基或COR B; R B是氢，烷基，取代的烷基，烷氧基，取代的烷氧基，氨基烷基或取代的氨基烷基; R 7是氢或烷基; 或其药学上可接受的盐。

    Adaptable payload processes
    8.
    发明申请
    Adaptable payload processes 有权
    适应性有效载荷流程

    公开(公告)号：US20050224650A1

    公开(公告)日：2005-10-13

    申请号：US10811771

    申请日：2004-03-29

    申请人： Raymond Reed ,  Martin Grether ,  W. Frantz ,  Gina Pischke ,  Kelly Morgan ,  Paul Fortado ,  Todd Jones ,  Douglas Hackett

    发明人： Raymond Reed ,  Martin Grether ,  W. Frantz ,  Gina Pischke ,  Kelly Morgan ,  Paul Fortado ,  Todd Jones ,  Douglas Hackett

    IPC分类号： B64C1/00 ,  B64C1/18

    CPC分类号： B64C1/18

    摘要： Processes for positioning, securing, and repositioning payload assemblies onto floor assemblies are disclosed. In one embodiment, a method includes forming a support structure having a plurality of elongated engagement members, each engagement member including an engagement surface adapted to support a load; forming an adaptable payload assembly that includes a payload member and at least one payload support coupled to the payload member, the payload support being adapted to transmit loads from the payload member to at least one engagement member, the payload support being moveable with the payload member relative to the support structure; and removeably coupling the payload support to at least one of the engagement surfaces of the engagement members. In an alternate embodiment, the engagement surfaces are at least one of approximately flush with and recessed below a lower surface of a panel supported by the support structure.

    摘要翻译： 公开了用于将有效载荷组件定位，固定和重新定位到地板组件上的过程。 在一个实施例中，一种方法包括形成具有多个细长接合构件的支撑结构，每个接合构件包括适于支撑负载的接合表面; 形成适应性有效载荷组件，其包括有效负载部件和耦合到所述有效负载部件的至少一个有效负载，所述有效负载支撑件适于将负载从所述有效负载部件传输到至少一个接合部件，所述有效载荷支撑件可与所述有效负载部件 相对于支撑结构; 以及将所述有效载荷支撑件可移除地联接到所述接合构件的至少一个接合表面。 在替代实施例中，接合表面与由支撑结构支撑的面板的下表面之间大致平齐并且在其下方凹入中的至少一个。

    Non-protruding seat track apparatus and methods
    9.
    发明申请
    Non-protruding seat track apparatus and methods 有权
    非突出的座椅轨道装置和方法

    公开(公告)号：US20050211833A1

    公开(公告)日：2005-09-29

    申请号：US10811528

    申请日：2004-03-29

    申请人： Walter Frantz ,  Gina Pischke ,  Martin Grether ,  Todd Jones ,  Cory Hitchcock ,  Paul Fortado

    发明人： Walter Frantz ,  Gina Pischke ,  Martin Grether ,  Todd Jones ,  Cory Hitchcock ,  Paul Fortado

    IPC分类号： B64C1/20

    CPC分类号： B64C1/20

    摘要： Non-protruding seat track apparatus and methods are disclosed. In one embodiment, a track includes an elongated support having a support surface and an engagement surface. The support surface is adapted to engage a lower surface of a floor panel, and the engagement surface is adapted to be coupled to a payload assembly. The engagement surface is at least one of flush with and recessed below the lower surface of the floor panel when the support surface is engaged with the lower surface. The engagement surface may have at least one of an engagement slot and an attachment aperture disposed therein.

    摘要翻译： 公开了非突出的座椅轨迹装置和方法。 在一个实施例中，轨道包括具有支撑表面和接合表面的细长支撑件。 支撑表面适于接合底板的下表面，并且接合表面适于联接到有效载荷组件。 当支撑表面与下表面接合时，接合表面是与地板镶板的下表面齐平且凹入的至少一个。 接合表面可以具有布置在其中的接合槽和附接孔中的至少一个。