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公开(公告)号:US08673345B2
公开(公告)日:2014-03-18
申请号:US11968755
申请日:2008-01-03
申请人: Andrew J. Bevacqua , Peter J. Lentini , Tracy N. Keeler , Julius R. Zecchino , Pauline Vassiliou
发明人: Andrew J. Bevacqua , Peter J. Lentini , Tracy N. Keeler , Julius R. Zecchino , Pauline Vassiliou
CPC分类号: A61K9/0014 , A61K8/0216 , A61K8/345 , A61K8/35 , A61K8/39 , A61K8/731 , A61K8/8129 , A61K8/8176 , A61K8/97 , A61K9/7007 , A61K2800/882 , A61Q17/04 , A61Q19/02 , A61Q19/08
摘要: A kit and methods for delivering an effective amount of a labile active to the skin are provided. The kit and methods comprise a composition comprising an effective amount of a labile active agent incorporated into a water-soluble polymeric film and an additive composition capable of dissolving the water-soluble polymeric film.
摘要翻译: 提供了将有效量的不稳定活性物质递送至皮肤的试剂盒和方法。 试剂盒和方法包括包含有效量的掺入水溶性聚合物膜的不稳定活性剂和能够溶解水溶性聚合物膜的添加剂组合物的组合物。
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公开(公告)号:US5304334A
公开(公告)日:1994-04-19
申请号:US874933
申请日:1992-04-28
IPC分类号: A61K9/107 , A61K8/00 , A61K8/03 , A61K8/06 , A61K8/41 , A61K8/70 , A61K8/72 , A61K8/73 , A61K8/81 , A61K8/89 , A61K8/891 , A61K9/113 , A61K9/127 , A61Q19/00 , B01F17/52 , B01J13/00 , C08L83/04 , C09K19/36 , C09K19/54 , A61K31/78 , A61K31/785
CPC分类号: B01J13/00 , A61K8/066 , A61K8/70 , A61K9/113 , A61K9/1274 , A61Q19/00 , C09K2019/525 , Y10S514/847 , Y10S514/937 , Y10S514/944 , Y10S516/90 , Y10S516/902
摘要: The instant invention relates to methods of preparing and stabilizing complex multiphase compositions that include distinct phases of water, gel, liquid crystal or oil and perfluoropolyether dispersed in a continuous phase of a silicone fluid. In particular, the present invention relates to a method of preparing a stable multiphase composition comprising the steps of mixing an aqueous solution of a water-soluble polymeric emulsifier, a silicone-based emulsifier and an oleophobic, hydrophobic silicone fluid in amounts effective to form a stable water-in-silicone emulsion; mixing the water-in-silicone emulsion with a hydrophilic gel comprising a homogeneous mixture of water and a sufficient amount of at least one viscosity-enhancing, water-soluble polymer, the emulsion and gel being combined in amounts effective to form a dispersion in which the gel is dispersed in the emulsion; and adding to the dispersion an oil or a thermotropic liquid crystal and a perfluoropolyether in amounts effective to form a stable, multiphase composition comprising a continuous phase of silicone fluid and independent, polydisperse phases of water, gel, oil or liquid crystal and perfluoropolyether.
摘要翻译: 本发明涉及制备和稳定复合多相组合物的方法,所述组合物包括分散在有机硅流体的连续相中的水,凝胶,液晶或油的不同相和全氟聚醚。 特别地,本发明涉及一种制备稳定多相组合物的方法,包括以下步骤:将水溶性聚合乳化剂,硅氧烷基乳化剂和疏油疏水硅氧烷流体的水溶液混合,其量有效地形成 稳定的硅氧烷硅乳液; 将水包硅乳液与亲水性凝胶混合,其包含水和足够量的至少一种增稠粘度的水溶性聚合物的均匀混合物,所述乳液和凝胶以有效形成分散体的量组合,其中 凝胶分散在乳液中; 并且将有效形成稳定的多相组合物的油或热致液晶和全氟聚醚加入到该分散体中,所述多相组合物包含硅油流体的连续相和水,凝胶,油或液晶和全氟聚醚的独立的多分散相。
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公开(公告)号:US20090156689A1
公开(公告)日:2009-06-18
申请号:US12369230
申请日:2009-02-11
申请人: George Cioca , Vasile Ionita-Manzatu , Liliana George , Paolo U. Giacomoni , Andrew J. Bevacqua , Harvey Gedeon , Charles Craig Tadlock , Donald F. Collins , Thomas Mammone , Daniel H. Maes , Christina G. Fthenakis
发明人: George Cioca , Vasile Ionita-Manzatu , Liliana George , Paolo U. Giacomoni , Andrew J. Bevacqua , Harvey Gedeon , Charles Craig Tadlock , Donald F. Collins , Thomas Mammone , Daniel H. Maes , Christina G. Fthenakis
CPC分类号: A61Q19/00 , A61K8/97 , A61K8/99 , A61K35/32 , A61K36/064 , A61K36/14 , A61K36/185 , A61K36/21 , A61K36/23 , A61K36/28 , A61K36/38 , A61K36/48 , A61K36/484 , A61K36/53 , A61K36/54 , A61K36/58 , A61K36/738 , A61K36/82 , A61K36/87 , A61K36/886 , A61K36/896 , A61K36/9068 , A61K38/39 , A61K2800/28 , A61K2800/85 , A61K2300/00
摘要: The present invention relates to a method of modulating a selected biological activity of a naturally occurring material having one or more biological activities in an extract of the naturally occurring material, the method comprising incubating the extract in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to modulate the selected activity with respect to baseline activity of the unincubated extract. The invention also relates to the bioconverted material so prepared, and the use of same in cosmetic or pharmaceutical compositions.
摘要翻译: 本发明涉及在天然存在的材料的提取物中调节具有一种或多种生物活性的天然存在物质的选定生物活性的方法,所述方法包括在有氧代谢微生物存在下将培养基中的提取物 在合适的有氧条件下,足以调节相对于未温育的提取物的基线活性的选定活性的时间。 本发明还涉及如此制备的生物转化材料及其在化妆品或药物组合物中的用途。
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公开(公告)号:US06753002B2
公开(公告)日:2004-06-22
申请号:US10391367
申请日:2003-03-18
IPC分类号: A61K700
CPC分类号: A61Q1/08 , A61K8/26 , A61K2800/434 , A61Q1/02
摘要: The invention relates to cosmetic composition comprising a fluorescent-effective amount of at least one fluorescent mineral powder, in combination with a cosmetically acceptable vehicle, wherein the powder, when the composition is applied, does not substantially alter the color of the skin. The compositions of the invention can be used as color cosmetics and skin treatment products, to replenish the skin's natural fluorescent glow.
摘要翻译: 本发明涉及包含荧光有效量的至少一种荧光矿物粉末与化妆品可接受的载体的化妆品组合物,其中当施用组合物时,粉末基本上不改变皮肤的颜色。 本发明的组合物可用作彩色化妆品和皮肤处理产品,以补充皮肤的天然荧光发光。
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公开(公告)号:US06592882B2
公开(公告)日:2003-07-15
申请号:US09320602
申请日:1999-05-26
IPC分类号: A61K700
CPC分类号: A61Q1/08 , A61K8/26 , A61K2800/434 , A61Q1/02
摘要: The invention relates to cosmetic composition comprising a fluorescent-effective amount of at least one fluorescent mineral powder, in combination with a cosmetically acceptable vehicle, wherein the powder, when the composition is applied, does not substantially alter the color of the skin. The compositions of the invention can be used as color cosmetics and skin treatment products, to replenish the skin's natural fluorescent glow.
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公开(公告)号:US5705145A
公开(公告)日:1998-01-06
申请号:US697230
申请日:1996-08-21
IPC分类号: A61K8/00 , A61K8/33 , A61K8/35 , A61K8/36 , A61K8/365 , A61K8/49 , A61K8/97 , A61Q17/04 , A61Q19/04 , A61K7/42 , A61K7/02
CPC分类号: A61K8/35 , A61K8/4946 , A61Q19/04 , Y10S514/938
摘要: Disclosed are cosmetic compositions for providing an artificial tan to skin which comprise dihydroxyacetone and an azole in a cosmetically or pharmaceutically acceptable carrier. Also disclosed is a method for providing an artificial tan to skin which comprises applying dihydroxyacetone and an azole to the skin.
摘要翻译: 公开了用于在化妆品或药学上可接受的载体中提供包含二羟基丙酮和唑的人造棕褐色的化妆品组合物。 还公开了一种提供皮肤的人造棕褐色的方法,其包括向皮肤施用二羟基丙酮和唑。
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公开(公告)号:US06777450B1
公开(公告)日:2004-08-17
申请号:US09580743
申请日:2000-05-26
申请人: Liliana George , Andrew J. Bevacqua , Gheorghe Cioca , Michelle Matathia , Charles Craig Tadlock
发明人: Liliana George , Andrew J. Bevacqua , Gheorghe Cioca , Michelle Matathia , Charles Craig Tadlock
IPC分类号: B01F308
CPC分类号: A61K8/066 , A61Q5/00 , A61Q19/00 , Y10S435/839 , Y10S514/938 , Y10S514/941 , Y10S514/943 , Y10S516/902 , Y10S526/932
摘要: The invention relates to a water-thin emulsion comprising a non-phospholipid, non-ethoxylated pseudoemulsifier system, the system having a chemical composition with at least one hydrophobic moiety and at least one polar moiety, the size, shape and/or planar arrangement of the hydrophobic and polar moieties being asymmetrical with respect to each other. The emulsion of the invention is prepared by high-pressure homogenization of a crude oil and water emulsion containing the pseudoemulsifier. The emulsions require little or no traditional emulsifier to maintain stability, and are particularly useful in the preparation of multiple emulsions.
摘要翻译: 本发明涉及包含非磷脂,非乙氧基化的假乳化剂体系的水稀薄乳液,该系统具有至少一个疏水部分和至少一个极性部分的化学组成,其尺寸,形状和/或平面布置 疏水和极性部分相对于彼此不对称。 本发明的乳液通过含有假乳化剂的原油和水乳液的高压匀浆制备。 乳液需要很少或没有传统的乳化剂来保持稳定性,并且特别可用于制备多重乳液。
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公开(公告)号:US06451328B1
公开(公告)日:2002-09-17
申请号:US09632059
申请日:2000-08-03
IPC分类号: A61K600
CPC分类号: C02F1/68 , A61K8/19 , A61K8/23 , A61K8/24 , A61K8/347 , A61K8/676 , A61K8/678 , A61K8/965 , A61K8/97 , A61K9/143 , A61K31/00 , A61K33/00 , A61K36/16 , A61K36/53 , A61K36/82 , A61K41/0004 , A61K45/06 , A61K2800/522 , A61Q17/00 , A61Q19/00 , A61Q19/08 , C02F1/005 , C02F1/4618 , A61K31/375 , A61K31/35 , A61K31/19 , A61K2300/00
摘要: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.
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公开(公告)号:US06239088B1
公开(公告)日:2001-05-29
申请号:US09273061
申请日:1999-03-19
申请人: Liliana George , Andrew J. Bevacqua , Daniela Toma , Saul Miklean
发明人: Liliana George , Andrew J. Bevacqua , Daniela Toma , Saul Miklean
IPC分类号: C11D166
摘要: The present invention relates to a cleansing composition based on the composition of lachrymal fluid. The cleansing composition comprises an ionic aqueous base containing one or more electrolytes, a basic protein or amino acid, and optionally, a mucomimetic compound and a lysozyme. The cleansing composition is gentle to both skin and eyes, and is highly effective in removing even transfer-resistant makeup.
摘要翻译: 本发明涉及一种基于泪液组成的清洁组合物。 清洁组合物包含含有一种或多种电解质,碱性蛋白质或氨基酸以及任选的模拟化合物和溶菌酶的离子水性碱。 清洁组合物对皮肤和眼睛均柔和,并且在除去均匀耐转移的化妆品方面非常有效。
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公开(公告)号:US07323198B2
公开(公告)日:2008-01-29
申请号:US11190567
申请日:2005-07-27
CPC分类号: A61K31/375 , A61K33/00 , A61K36/00 , A61K45/06 , A61K2300/00
摘要: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.
摘要翻译: 本发明涉及结构化水及其抗氧化活性。 此外,本发明涉及掺入正电(S水)或电负性(I水)的簇结构内的抗氧化剂。 在其簇结构内具有抗氧化剂的结构化水对抗氧化剂具有稳定作用。 此外,结构化水固有的抗氧化活性通过其簇结构内的抗氧化剂的存在而增强。 本发明还包括去除或减少皮肤上的自由基并因此防止皮肤老化的迹象和与皮肤中存在自由基相关的癌症风险的方法。
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