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    Devices, systems and methods for facilitating facemask compliance
    2.
    发明授权
    Devices, systems and methods for facilitating facemask compliance 有权

    公开(公告)号：US10350375B2

    公开(公告)日：2019-07-16

    申请号：US14985832

    申请日：2015-12-31

    申请人： Anthony James Hickey ,  Timothy M. Crowder

    发明人： Anthony James Hickey ,  Timothy M. Crowder

    IPC分类号： A61M16/06 ,  A61M16/00 ,  A61M15/00 ,  A61M21/00 ,  A61M11/02 ,  A61M21/02

    摘要： A facemask includes a facemask body, a plurality of electrical contacts and a control circuit. The facemask body has an end including an opening and a skin contact perimeter extending along a periphery of the opening, with the skin contact perimeter configured to sealingly engage with a user's face. Each electrical contact is disposed at a respective region of the skin contact perimeter, and each electrical contact is configured to sense when the respective region of the skin contact perimeter is sealingly engaged with a user's face. The control circuit is disposed on the facemask body, and the control circuit is configured to receive a signal from each electrical contact when the respective region of the skin contact perimeter is sealingly engaged with a user's face and to initiate output of an audible stimulus and/or a visual stimulus in response to receiving a concurrent signal from all of the plurality of electrical contacts.

    Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
    4.
    发明授权
    Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages 有权
    干粉吸入器，相关的泡罩装置以及分配干粉物质的相关方法和制造吸塑包装

    公开(公告)号：US06889690B2

    公开(公告)日：2005-05-10

    申请号：US10434009

    申请日：2003-05-08

    申请人： Timothy M. Crowder ,  Anthony J. Hickey ,  Jeffrey A. Warden

    发明人： Timothy M. Crowder ,  Anthony J. Hickey ,  Jeffrey A. Warden

    IPC分类号： B65B1/08 ,  A61M15/00 ,  B65B37/04 ,  B65D88/66 ,  B65G53/40 ,  B65G53/66 ,  A61M16/00 ,  B05D7/14 ,  B65D83/06

    CPC分类号： B65D88/66 ,  A61M15/0003 ,  A61M15/0005 ,  A61M15/001 ,  A61M15/0048 ,  A61M15/0051 ,  A61M15/0055 ,  A61M15/0065 ,  A61M15/0075 ,  A61M2202/064 ,  A61M2205/18 ,  A61M2205/35 ,  A61M2205/52 ,  A61M2205/8206 ,  B65B37/04 ,  B65G53/66

    摘要： The present invention includes dry powder inhalers and associated multi-dose dry powder packages for holding inhalant formulated dry powder substances and associated fabrication and dispensing methods. The multi-dose package can include a platform body comprising at least one thin piezoelectric polymer material layer defining at least a portion of a plurality of spatially separated discrete elongate dry powder channels having an associated length, width and height; and a metallic material attached to selected portions of the piezoelectric polymer material including each of the regions corresponding to the elongate dry powder channels to, in operation, define active energy releasing vibratory channels. In operation, the elongate channels can be selectively individually activated to vibrate upon exposure to an electrical input.The dry powder inhaler includes an elongate body having opposing first and second outer primary surfaces with a cavity therebetween and having opposing top and bottom end portions and a multi-dose sealed blister package holding a plurality of discrete meted doses of a dry powder inhalable product located in the cavity of the elongate body. The inhaler also includes an inhalation port formed in the bottom end portion of the elongate body, the inhalation port configured to be in fluid communication with at least one of the discrete meted doses during use and a cover member that is pivotably attached to the elongate body so that it remains attached to the body during normal operational periods of use and moves to a first closed position to overlie the inhalation port at the bottom end portion of the body during periods of non-use and moves to a second open position away from the inhalation port during periods of use to allow a user to access the inhalation port.

    摘要翻译： 本发明包括干粉吸入器和用于保持吸入配方干粉物质的相关多剂量干粉包装以及相关的制造和分配方法。 所述多剂量包装可以包括平台体，其包括至少一个薄的压电聚合物材料层，所述至少一个薄的压电聚合物材料层限定具有相关联的长度，宽度和高度的多个空间分离的离散细长干粉通道的至少一部分; 以及附着到压电聚合物材料的选定部分的金属材料，包括对应于细长干燥粉末通道的每个区域，以在操作中限定释放活化能量的振动通道。 在操作中，细长通道可以选择性地单独启动以在暴露于电输入时振动。 干粉吸入器包括细长体，其具有相对的第一和第二外部主表面，其间具有空腔并具有相对的顶部和底部部分，以及多剂量密封的泡罩包装，其保持多个不连续的剂量的干粉末可吸入产品， 在细长体的空腔中。 吸入器还包括形成在细长体的底端部分中的吸入口，该吸入口构造成在使用期间与至少一个离散的剂量流体连通;以及盖构件，其可枢转地附接到细长体 使得其在正常操作使用期间保持附接到身体，并且在非使用期间移动到第一关闭位置以覆盖身体的底端部分处的吸入口，并且移动到离开该位置的第二打开位置 吸入口在使用期间允许使用者进入吸入口。

    Dry powder dose filling systems and related methods
    7.
    发明授权
    Dry powder dose filling systems and related methods 有权
    干粉剂量灌装系统及相关方法

    公开(公告)号：US06985798B2

    公开(公告)日：2006-01-10

    申请号：US10606678

    申请日：2003-06-26

    申请人： Timothy M. Crowder ,  Anthony J. Hickey

    发明人： Timothy M. Crowder ,  Anthony J. Hickey

    IPC分类号： G06F17/00

    CPC分类号： A61M15/0045 ,  A61M15/0003 ,  A61M15/0005 ,  A61M15/001 ,  A61M15/0048 ,  A61M15/0051 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/0075 ,  A61M15/0083 ,  A61M2202/064 ,  A61M2205/18 ,  A61M2205/35 ,  A61M2205/52 ,  A61M2205/8206 ,  B65B37/04 ,  B65D88/66 ,  B65G53/66

    摘要： Methods for flowably dispensing dry powders from a hopper having a dispensing port and a dry powder flow path can include: (a) generating a first non-linear vibration input signal, the first non-linear input signal comprising a plurality of different selected frequencies that correspond to a first dry powder formulation; (b) applying the first non-linear vibration input signal to a dispensing hopper having at least one dispensing port while the first dry powder formulation is flowing therethrough; and (c) dispensing a first meted quantity of the first dry powder through the dispensing port to a receiving member. Related devices and computer program products for dispensing dry powders are also described.

    摘要翻译： 从具有分配端口和干粉流路的料斗流动地分配干粉的方法可以包括：（a）产生第一非线性振动输入信号，第一非线性输入信号包括多个不同的选定频率， 对应于第一干粉配方; （b）当所述第一干粉制剂流过其中时，将第一非线性振动输入信号施加到具有至少一个分配端口的分配料斗; 和（c）将第一量的第一干粉通过分配口分配到接收构件。 还描述了用于分配干粉的相关设备和计算机程序产品。

    Apparatus, systems and related methods for dispensing and /or evaluating dry powders
    9.
    发明授权
    Apparatus, systems and related methods for dispensing and /or evaluating dry powders 有权
    用于分配和/或评估干粉的装置，系统和相关方法

    公开(公告)号：US07118010B2

    公开(公告)日：2006-10-10

    申请号：US10607389

    申请日：2003-06-26

    申请人： Timothy M. Crowder ,  Anthony J. Hickey ,  Vanessa Boekestein

    发明人： Timothy M. Crowder ,  Anthony J. Hickey ,  Vanessa Boekestein

    IPC分类号： B67B7/00

    CPC分类号： A61M15/0045 ,  A61M15/0003 ,  A61M15/0005 ,  A61M15/001 ,  A61M15/0048 ,  A61M15/0051 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/0075 ,  A61M15/0083 ,  A61M2202/064 ,  A61M2205/18 ,  A61M2205/35 ,  A61M2205/52 ,  A61M2205/8206 ,  B65B37/04 ,  B65D88/66 ,  B65G53/66

    摘要： Methods, systems, and computer program products flowably dispense meted amounts of dry powders using a flexing piezoelectric layer to transmit a vibratory signal to the dry powder to facilitate fluidic flow through a flow channel. The apparatus for dispensing dry powders can include: (a) an elongate flow channel having a width, length, and depth, the flow channel having axially spaced apart inlet and outlet ports, wherein the elongate flow channel is configured to extend in an angular orientation of between about 10–75 degrees relative to the axial direction of flow; (b) a flexible piezoelectric layer configured to overlie the flow channel so that, in operation, the piezoelectric layer is able to flex upwardly away from the lowermost portion of the underlying flow channel; and (c) a signal generator operatively associated with the piezoelectric layer, wherein, in operation, the signal generator is configured to output a signal for flexing the piezoelectric layer in the elongate flow channel.

    摘要翻译： 方法，系统和计算机程序产品使用弯曲压电层可流动地分配大量的干粉，以将振动信号传递到干粉，以促进流过流动通道的流体流动。 用于分配干燥粉末的设备可以包括：（a）具有宽度，长度和深度的细长流动通道，流动通道具有轴向间隔开的入口和出口，其中细长流动通道构造成以角度方向 相对于流动的轴向方向在约10-75度之间; （b）柔性压电层，其构造成覆盖流动通道，使得在操作中，压电层能够向上挠曲离开底层流动通道的最下部; 和（c）与所述压电层可操作地相关联的信号发生器，其中在操作中，所述信号发生器被配置为输出用于使所述压电层在所述细长流动通道中弯曲的信号。