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公开(公告)号：US5316179A
公开(公告)日：1994-05-31
申请号：US837897
申请日：1992-02-20
摘要： A system for delivering measured amounts of liquid, such as reagents used in chromatography. Liquid is first moved under gas pressure from a reservoir, such as a reagent bottle, through a valve into a narrow pipe. It reaches a detector which, detecting its presence, closes the valve thus trapping an amount of liquid between the valve and the detector, this amount of liquid then constituting a `unit` or `pulse` of liquid. The movement of the valve is used to connect a gas supply which drives the `unit` or `pulse` out of the pipe to an ultimate destination, such as a chromatographic column. A further `unit` or `pulse` can then be moved into the pipe and this repeated so that delivery to the destination is made in a series of such `units` or `pulse`. By timing the delivery of one `unit` or `pulse`, an amount less than one `unit` or `pulse` can be delivered by passing liquid into the pipe for less than the time taken to deliver one `unit`. This can be used to make up a delivery which is not a unitary multiple of one `unit` or to deliver a small amount of less than one `unit`. No moving parts are involved and delivery of accurately measured amounts is achieved.
摘要翻译： 用于输送测量量的液体的系统，例如色谱中使用的试剂。 液体首先在气体压力下从诸如试剂瓶的储存器通过阀移动到窄管中。 它到达检测器，检测其存在，关闭阀，从而在阀和检测器之间捕获一定量的液体，然后该量的液体构成液体的“单位”或“脉冲”。 阀的运动用于连接将“单元”或“脉冲”从管道驱动到最终目的地（如色谱柱）的气体源。 然后可以将另外的“单位”或“脉冲”移动到管道中，并重复进行，以便以一系列这样的“单位”或“脉冲”来传送到目的地。 通过定时输送一个“单位”或“脉冲”，通过将液体通入管道中可以传递少于一个“单位”或“脉冲”的量可以通过少于传送一个单元所需的时间来传送。 这可以用于组成一个“单位”的单位倍数的交付，或者提供少于一个“单位”的少量。 不涉及移动部件，实现准确测量量的传递。
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公开(公告)号：US5294023A
公开(公告)日：1994-03-15
申请号：US765386
申请日：1991-09-25
申请人： Antonis C. Ioannides , Alan Pindar
发明人： Antonis C. Ioannides , Alan Pindar
CPC分类号： B01L3/0293 , G01F1/34 , G01N30/32 , G05D7/0658 , G01N2030/324 , G01N2030/326
摘要： A liquid delivery system which can deliver liquid from a pressurized vessel holding a volume of the liquid, out through an outlet under a controlled pressure, thereby controlling the delivery rate of the liquid. The vessel can be re-filled while controlled liquid delivery continues, either by re-filling directly into the vessel and allowing any excess of pressure to be relieved, or by using a second pressurized vessel and continuing delivery from one vessel while the other is re-filled.
摘要翻译： 液体输送系统，其可以将来自保持一定体积的液体的加压容器的液体从受控压力的出口输出，从而控制液体的输送速率。 可以在控制的液体输送继续的同时重新填充容器，通过直接重新填充到容器中并允许任何过量的压力被释放，或者通过使用第二加压容器并且从一个容器继续输送，而另一个是再次 -填充。
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公开(公告)号：US5422079A
公开(公告)日：1995-06-06
申请号：US159507
申请日：1993-11-30
IPC分类号： B01L7/00 , C07H1/00 , C07H1/06 , G01N1/28 , G01N30/06 , G01N30/24 , G01N30/46 , G01N30/60 , G01N30/88 , G01N35/00 , G01N33/00
CPC分类号： B01L7/00 , C07H1/00 , C07H1/06 , G01N1/28 , G01N30/24 , G01N35/00712 , G01N2030/8881 , G01N2035/00376 , G01N2035/00415 , G01N30/06 , G01N30/466 , G01N30/6043 , G01N30/6091
摘要： An instrument that is particularly designed for the automatic release and isolation saccharides from glycoconjugates comprises a source of inert gas that can be passed along a line, to bring together all the required reagents with the sample, heat the sample in the presence of the reagents for the required time and at the required temperature, pass the resultant mixtures through chromatographic columns, and deliver the separated material to a collection point. The release and separation can be conducted on two samples of glycoconjugate simultaneously, even when the samples are of different glycoconjugates requiring different processing parameters. The material of one sample can be prevented from mixing with or otherwise contaminating the material of the other sample.
摘要翻译： 特别设计用于自动释放和分离来自糖缀合物的糖的仪器包括可以沿线通过的惰性气体源，以将所有所需的试剂与样品组合在一起，在样品存在下加热样品 所需时间和所需温度，将所得混合物通过色谱柱，并将分离的物质输送到收集点。 即使当样品具有不同的糖缀合物需要不同的加工参数时，也可以同时对两个糖缀合物样品进行释放和分离。 可以防止一个样品的材料与另一个样品的材料混合或以其他方式污染另一个样品的材料。
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公开(公告)号：US5357996A
公开(公告)日：1994-10-25
申请号：US117982
申请日：1993-09-08
申请人： Antonis C. Ioannides , Alan Pindar
发明人： Antonis C. Ioannides , Alan Pindar
IPC分类号： G05D16/20
CPC分类号： G05D16/2033 , G05D16/2053 , G05D16/206 , Y10T137/0379 , Y10T137/7761 , Y10T137/86187
摘要： A fluid pressure control system comprising a first chamber, the pressure in which is to be controlled, a second chamber and a valve means for controlling communication between the first and second chambers. A controller is arranged such that, if the pressure in the first chamber differs from a required pressure, the controller i) operates the valve means to close off communication between the first and second chambers, ii) varies the pressure in the second chamber, iii) opens communication between the first and second chambers to deliver a discrete pressure step to the first chamber, and, iv) repeats i) to iii) until the pressure in the first chamber reaches a required level.
摘要翻译： 一种流体压力控制系统，包括第一室，待控制的压力，第二室和用于控制第一和第二室之间的连通的阀装置。 控制器被布置成使得如果第一室中的压力与所需压力不同，则控制器i）操作阀装置以关闭第一和第二室之间的连通，ii）改变第二室中的压力，iii ）打开第一和第二腔室之间的连通，以将离散的压力步骤递送到第一腔室，以及iv）重复i）至iii）直到第一腔室中的压力达到所需水平。
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