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    Anhydrovinblastine for the treatment of cancer
    5.
    发明授权
    Anhydrovinblastine for the treatment of cancer 失效
    用于治疗癌症的脱氢长春花碱

    公开(公告)号：US06326376B1

    公开(公告)日：2001-12-04

    申请号：US09380540

    申请日：2000-01-21

    申请人： Bruce Schmidt ,  James Kutney ,  Lawrence Mayer

    发明人： Bruce Schmidt ,  James Kutney ,  Lawrence Mayer

    IPC分类号： A61K3144

    CPC分类号： A61K31/475

    摘要： The present invention is particularly directed to the use of a derivative of vinblastine, 3′,4′-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3′,4′ position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an anti-neoplastic agent in the therapeutic treatment of cancer.

    摘要翻译： 本发明特别涉及长春碱，3'，4'-脱氢长春碱（AHVB）的衍生物，其与长春花碱不同，因为它在黄嘌呤核的3'，4'位具有双键，而不是 比在母体结构中存在的羟基作为癌症治疗性治疗中的抗肿瘤剂。

    Use of anhydrovinblastine
    6.
    发明授权
    Use of anhydrovinblastine 失效
    使用脱氢长春花碱

    公开(公告)号：US6011041A

    公开(公告)日：2000-01-04

    申请号：US690195

    申请日：1996-07-26

    申请人： Bruce Schmidt ,  James Kutney ,  Lawrence Mayer

    发明人： Bruce Schmidt ,  James Kutney ,  Lawrence Mayer

    IPC分类号： C07D519/04 ,  A61K31/33 ,  A61K31/485 ,  A61K43/42

    CPC分类号： C07D519/04 ,  Y10S514/908

    摘要： The present invention is particularly directed to the use of a derivative of vinblastine, 3',4'-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3',4' position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an antineoplastic agent in the therapeutic treatment of cancer. Specifically, the treatment of lymphoma with 3',4'-anhydrovinblastine is disclosed.

    摘要翻译： 本发明特别涉及长春碱，3'，4'-脱氢长春碱（AHVB）的衍生物，其与长春花碱不同，因为它在黄嘌呤核的3'，4'位具有双键，而不是 比在母体结构中存在的羟基作为癌症治疗性治疗中的抗肿瘤剂。 具体地，公开了用3'，4'-脱氢长春花碱治疗淋巴瘤。

    Portable heated stadium seat and method
    7.
    发明申请
    Portable heated stadium seat and method 有权
    便携式加热体育场座椅及方法

    公开(公告)号：US20070152479A1

    公开(公告)日：2007-07-05

    申请号：US11321436

    申请日：2005-12-29

    申请人： John Howman ,  Bruce Schmidt

    发明人： John Howman ,  Bruce Schmidt

    IPC分类号： A47C7/74 ,  A47C4/30

    CPC分类号： A47C7/748 ,  A47C7/021 ,  A47C7/425

    摘要： A portable stadium seat having a base and a back for use on bleacher or hard plastic seating is disclosed which has heated seat and backrest members and a self-contained, rechargeable electrical power source for operating an electrical heating element contained in each of the seat and backrest members. The backrest member is hingedly mounted on the seat member, such that it may be folded flat onto the seat member for ease of portability and storage, and the portable heated stadium seat includes a carrying strap to enhance the portability of the portable heated stadium seat. An external recharger is used to charge the batteries prior to use, with the portable heated stadium seat thus being useable in locations where electrical power is not easily accessible.

    摘要翻译： 公开了具有用于漂白机或硬塑料座椅的基座和背部的便携式体育场座椅，其具有加热的座椅和靠背构件以及用于操作包含在座椅和座椅中的每一个中的电加热元件的独立可再充电电源 靠背成员 靠背构件被铰接地安装在座椅构件上，使得它可以平放地折叠到座椅构件上，以便于便携和存储，并且便携式加热体育场座椅包括携带带，以增强便携式加热的体育场座椅的便携性。 外部充电器用于在使用之前对电池充电，便携式加热的体育场座椅因此可用于电力不容易接近的位置。

    Hydraulic Level-Loading and Dumping Trailer
    8.
    发明申请
    Hydraulic Level-Loading and Dumping Trailer 失效
    液压装载和倾倒拖车

    公开(公告)号：US20070059137A1

    公开(公告)日：2007-03-15

    申请号：US11552838

    申请日：2006-10-25

    申请人： Bruce Schmidt

    发明人： Bruce Schmidt

    IPC分类号： B60P1/04

    CPC分类号： B60P1/025 ,  B60P3/122

    摘要： A trailer, having the capability of lowering its deck to the ground surface for ease of loading and unloading from the ground; raising its deck to a loading dock height for ease of loading and unloading from a loading dock or other elevated surface; and tilting its deck for dumping is disclosed. The deck is maintained in a transport position for travel. All the changes in position may be effected by a single actuator. Rollers, affixed to a rail affixed to the deck roll inside C-channels affixed to the frame arranged at a diagonal to the vertical when raising or lowering.

    摘要翻译： 一种拖车，具有将甲板降低到地面的能力，便于从地面上卸载; 将其甲板提升至装卸坞高度，以便于从装载码头或其他高架表面装载和卸载; 并倾斜其甲板倾倒。 甲板保持在运输位置进行旅行。 所有的位置变化都可以通过单个执行机构实现。 辊子，固定到固定在C形通道上的甲板辊上的轨道，其固定在框架上，在升高或降低时与竖直对角线布置。

    Hydraulic level-loading and dumping trailer
    9.
    发明申请
    Hydraulic level-loading and dumping trailer 有权
    液压装载和倾倒拖车

    公开(公告)号：US20060045694A1

    公开(公告)日：2006-03-02

    申请号：US10932410

    申请日：2004-09-02

    申请人： Bruce Schmidt

    发明人： Bruce Schmidt

    IPC分类号： B60P1/04

    CPC分类号： B60P1/025 ,  B60P3/122

    摘要： A trailer, having the capability of lowering its deck to the ground surface for ease of loading and unloading from the ground; raising its deck to a loading dock height for ease of loading and unloading from a loading dock or other elevated surface; and tilting its deck for dumping is disclosed. The deck is maintained in a transport position for travel. All the changes in position may be effected by a single actuator. Rollers, affixed to a rail affixed to the deck roll inside C-channels affixed to the frame arranged at a diagonal to the vertical when raising or lowering.

    摘要翻译： 一种拖车，具有将甲板降低到地面的能力，便于从地面上卸载; 将其甲板提升至装卸坞高度，以便于从装载码头或其他高架表面装载和卸载; 并倾斜其甲板倾倒。 甲板保持在运输位置进行旅行。 所有的位置变化都可以通过单个执行机构实现。 辊子，固定到固定在C形通道上的甲板辊上的轨道，其固定在框架上，在升高或降低时与竖直对角线布置。