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    POST-BIOPSY CAVITY TREATMENT IMPLANTS AND METHODS
    2.
    发明申请
    POST-BIOPSY CAVITY TREATMENT IMPLANTS AND METHODS 审中-公开
    后生物处理植入物和方法

    公开(公告)号：US20070299541A1

    公开(公告)日：2007-12-27

    申请号：US11850033

    申请日：2007-09-05

    申请人： Ary CHERNOMORSKY ,  James Vetter ,  Simon Chernomorsky

    发明人： Ary CHERNOMORSKY ,  James Vetter ,  Simon Chernomorsky

    IPC分类号： A61F2/02

    CPC分类号： A61M31/005 ,  A61B17/0057 ,  A61B90/39 ,  A61B2017/00654 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K49/04 ,  A61L31/146 ,  A61L31/18

    摘要： An implant for filling a cavity created by an excisional procedure includes first and second portions. The first portion may include a first collagenous matrix that defines a first selected crosslinking density and the second portion may include a second collagenous matrix that defines a second selected cross-linking density that is different than the first cross-linking density. The first and second cross-linking densities may be selected so as to cause the first and second portions to swell in such a manner that the implant swells into a size and a shape that is similar to the predetermined size and shape of the cavity when the implant is implanted. An aqueous solution may be added to the cavity if the cavity is not sufficiently aqueous to cause the implant to swell.

    摘要翻译： 用于填充由切除过程产生的空腔的植入物包括第一和第二部分。 第一部分可以包括限定第一选择的交联密度的第一胶原基质，并且第二部分可以包括限定不同于第一交联密度的第二选择的交联密度的第二胶原基质。 可以选择第一和第二交联密度以使得第一和第二部分以这样的方式膨胀，使得当第一和第二部分的膨胀成为与腔的预定尺寸和形状相似的尺寸和形状时，当 植入植入物。 如果空腔不足够水以引起植入物膨胀，则可将水溶液加入空腔中。

    DRUG DELIVERY SYSTEMS
    3.
    发明申请
    DRUG DELIVERY SYSTEMS 审中-公开
    药物递送系统

    公开(公告)号：US20100185146A1

    公开(公告)日：2010-07-22

    申请号：US12580162

    申请日：2009-10-15

    申请人： Kamal RAMZIPOOR ,  Ary CHERNOMORSKY

    发明人： Kamal RAMZIPOOR ,  Ary CHERNOMORSKY

    IPC分类号： A61M25/10

    CPC分类号： A61M25/10 ,  A61M2025/105

    摘要： Drug delivery systems which are configured to retain and then distribute one or more drugs upon an actuating surface and/or balloon for delivery to a tissue region are described herein. The drug delivery system may comprise in one variation a volume of one or more drugs held in a reservoir, e.g., a silo, which may be located proximally of the expandable actuating surface and/or balloon. The one or more drugs may be separated from one another by valves or immiscible fluid barriers for distribution upon the surface, which may be varied in pore distribution, have a coating or covering for facilitating drug distribution, etc.

    摘要翻译： 这里描述了被配置为保持并随后将一种或多种药物分配在致动表面和/或球囊上以递送至组织区域的药物递送系统。 药物递送系统可以在一个变体中包括一个或多个药物的体积，其保持在储存器例如筒仓中，储存器可位于可膨胀致动表面和/或气囊的近侧。 一种或多种药物可以通过阀或不混溶的流体屏障彼此分离，用于分布在表面上，其可以在孔分布中变化，具有用于促进药物分布的涂层或覆盖物等。

    POST-BIOPSY CAVITY TREATMENT IMPLANTS AND METHODS
    4.
    发明申请
    POST-BIOPSY CAVITY TREATMENT IMPLANTS AND METHODS 审中-公开
    后生物处理植入物和方法

    公开(公告)号：US20090149746A1

    公开(公告)日：2009-06-11

    申请号：US12273754

    申请日：2008-11-19

    申请人： Ary CHERNOMORSKY ,  John Soo Hoo ,  James W. Vetter

    发明人： Ary CHERNOMORSKY ,  John Soo Hoo ,  James W. Vetter

    IPC分类号： A61M25/00 ,  A61B6/00

    CPC分类号： A61B90/39 ,  A61B2017/00004 ,  A61B2017/00495 ,  A61B2090/3908 ,  A61B2090/3987

    摘要： A method of forming a soft tissue biopsy cavity marker may include steps of providing a radio-opaque element and a bio-compatible and bio-degradable polymer such as alginate and delivering the provided radio-opaque element and the provided polymer to a biopsy site, such as a breast biopsy site. A gelling initiator that includes divalent cations such as NaCl2 may then be provided and delivered to the biopsy site, causing the previously delivered polymer to gel and to form a soft tissue biopsy marker in situ (within the biopsy site).

    摘要翻译： 形成软组织活检腔标记物的方法可以包括提供不透辐射元件和生物相容性和生物可降解聚合物如藻酸盐的步骤，并将提供的不透射线的元件和所提供的聚合物递送到活检部位， 如乳房活检部位。 然后可以提供包括二价阳离子如NaCl2的胶凝引发剂，并将其递送至活检部位，使先前递送的聚合物凝胶化并在原位（活检部位内）形成软组织活检标记物。

    Post-biopsy cavity treatment implants and methods
    6.
    发明申请
    Post-biopsy cavity treatment implants and methods 失效
    活检后腔内治疗植入物和方法

    公开(公告)号：US20080114329A1

    公开(公告)日：2008-05-15

    申请号：US12018170

    申请日：2008-01-22

    申请人： Ary CHERNOMORSKY ,  James Vetter ,  Simon Chernomorsky

    发明人： Ary CHERNOMORSKY ,  James Vetter ,  Simon Chernomorsky

    IPC分类号： A61M31/00

    CPC分类号： A61L31/146 ,  A61B17/0057 ,  A61B90/39 ,  A61B2017/00654 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61K49/04 ,  A61L31/18

    摘要： A method of treating a cavity created by a percutaneous excisional procedure carried out through an incision includes steps of providing a post-procedure cavity implant, the post-procedure cavity implant including: a radiopaque element; a core portion coupled to the radiopaque element, the core portion including a first porous matrix defining a first controlled pore architecture, and a shell portion coupled to the core portion, the shell portion including a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture; implanting the post-procedure cavity implant into the cavity, and closing the incision.

    摘要翻译： 一种治疗由通过切口进行的经皮切除手术产生的腔的方法包括提供后程腔腔植入物的步骤，所述后程腔腔植入物包括：不透射线的元件; 芯部分，其连接到所述不透射线元件，所述芯部分包括限定第一受控孔结构的第一多孔基体和耦合到所述芯部分的壳部分，所述壳部分包括限定第二受控孔结构的第二多孔基体， 不同于第一受控孔结构; 将后程腔腔植入物植入腔中，并闭合切口。