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    Drug delivery PTCA catheter and method for drug delivery
    8.
    发明授权
    Drug delivery PTCA catheter and method for drug delivery 失效
    药物输送PTCA导管和药物递送方法

    公开(公告)号：US5397307A

    公开(公告)日：1995-03-14

    申请号：US163852

    申请日：1993-12-07

    申请人： Richard Goodin

    发明人： Richard Goodin

    IPC分类号： A61M25/00 ,  A61F2/00 ,  A61F2/958 ,  A61M29/02 ,  A61M29/00

    CPC分类号： A61M25/104 ,  A61M25/10 ,  A61F2250/0067 ,  A61M2025/1052 ,  A61M2025/1086 ,  A61M25/1002

    摘要： An intravascular material delivery dilation catheter having a pair of longitudinally spaced inflatable balloons with a drug delivery region defined therebetween. The catheter is ideally suited for use after a PTCA procedure, wherein the proximate balloon seals the blood vessel while the distal balloon is uniquely contoured when inflated to define fluid communication paths therepast and proximate a blood vessel to be treated. The distal balloon, when inflated, has four lobes but could also be textured. Each lobe is separated from the next by a groove, which groove in combination with the blood vessel inner wall forms a fluid communication path therebetween. Upon inflation of both balloons in a blood vessel, a medicament such as heparin can be injected, via the drug delivery region between the inflated balloons, wherein the medicament flows past the distal balloon at a selected rate. Accordingly, a medicament can be injected directly to a treatment site rather than injected as a bolus dose, thus, a smaller dosage may be employed to minimize side effects. Alternatively, perfusion can be accomplished by only partially inflating the proximate balloon to constrict flow therepast, or eliminating the proximate balloon entirely, where the drug delivery region is disposed upstream of the contoured distal balloon.

    摘要翻译： 一种血管内材料递送扩张导管，其具有一对纵向间隔开的可充气球囊，其间限定有药物递送区域。 该导管理想地适用于在PTCA程序之后使用，其中邻近气囊密封血管，而远端球囊在充气时是独特的轮廓，以限定其间的流体连通路径并且靠近要治疗的血管。 远端气球，当充气时，有四个瓣但也可以纹理。 每个叶片与下一个槽分隔开，该槽与血管内壁组合形成两者之间的流体连通路径。 当在血管中气囊膨胀时，药物如肝素可以经由充气气囊之间的药物递送区域被注入，其中药物以选定的速率流过远端球囊。 因此，药物可以直接注射到治疗部位而不是作为推注剂量注射，因此可以采用较小的剂量以使副作用最小化。 或者，灌注可以通过仅部分地充气邻近的气囊来收缩流体，或者完全消除邻近气囊，其中药物递送区域设置在轮廓远端球囊的上游。

    Dilatation Catheter with Enhanced Distal End for Crossing Occluded Lesions
    10.
    发明申请
    Dilatation Catheter with Enhanced Distal End for Crossing Occluded Lesions 审中-公开
    扩张导管，增强远端，用于穿过闭塞的病变

    公开(公告)号：US20100286721A1

    公开(公告)日：2010-11-11

    申请号：US12842825

    申请日：2010-07-23

    申请人： Richard Goodin ,  Robert E. Burgmeier

    发明人： Richard Goodin ,  Robert E. Burgmeier

    IPC分类号： A61M29/02

    CPC分类号： A61M25/104 ,  A61M2025/1086

    摘要： A catheter for crossing an occluding lesion with an inflatable balloon and dilating the lesion includes an inner tube that defines a longitudinal axis. The balloon includes a distal section that is bonded to the tube's distal end, a working section, and a conically shaped distal transition section connecting the working and distal section. A plurality of rigid ribs are spaced around the circumference of the balloon near the catheter's distal end. Each rib includes a first elongated portion attached to the balloon's distal section and aligned substantially parallel with the longitudinal axis. A second portion extending from the first portion and at an angle thereto is attached to and lies along the surface of the balloon's distal transition section. The plurality of ribs combine to simulate a stiff, tapered surface that can be wedged into the occluding lesion to create a passageway to cross the lesion with the balloon.

    摘要翻译： 用于使闭塞性病变与可充气气囊交叉并扩张病变的导管包括限定纵向轴线的内管。 气囊包括接合到管的远端的远侧部分，工作部分和连接工作部分和远端部分的锥形远端过渡部分。 多个刚性肋在导管的远端附近围绕球囊的圆周间隔开。 每个肋包括附接到气囊的远侧部分并基本上平行于纵向轴线排列的第一细长部分。 从第一部分延伸并且以其一定角度的第二部分附接到气囊的远端过渡部分的表面并且位于其中。 多个肋组合以模拟刚性的锥形表面，其可以楔入阻塞性损伤中以产生用气球穿过病变的通道。