-
公开(公告)号：US06919075B1
公开(公告)日：2005-07-19
申请号：US09830954
申请日：2000-08-31
Applicant: Beka Solomon , Dan Frenkel , Eilat Hanan
Inventor： Beka Solomon , Dan Frenkel , Eilat Hanan
IPC: G01N33/53 , A61K35/74 , A61K35/76 , A61K38/00 , A61K38/17 , A61K39/00 , A61K39/395 , A61K49/00 , A61P19/08 , A61P25/28 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N7/01 , C12N15/02 , A01N61/00 , C12N15/00 , C12N15/86
CPC classification number: A61K39/0007 , A61K38/1709 , A61K49/0004 , A61K2039/6075 , C07K14/47 , C07K14/4711 , C07K16/18 , C07K2317/622 , C07K2317/74 , C07K2319/00
Abstract: A method of immunizing against plaque forming diseases using display technology is provided. The method utilize novel agents, or pharmaceutical compositions for vaccination against plaque forming diseases which rely upon presentation of an antigen or epitope on a display vehicle. The method further includes agents, or pharmaceutical compositions for vaccination against plaque forming diseases, which rely upon presentation of an antibody, or an active portion thereof, on a display vehicle. Whether antigens or antibodies are employed, disaggregation of plaques results from the immunization.
Abstract translation: 提供了使用显示技术免疫斑块形成疾病的方法。 该方法利用依赖于在显示载体上呈递抗原或表位的新型药剂或药物组合物用于接种针对斑块形成疾病的疫苗。 该方法还包括依赖于在显示载体上呈递抗体或其活性部分的针对斑块形成疾病接种的药剂或药物组合物。 无论是使用抗原还是抗体，均免疫后产生斑块分解。
-
2.发明申请Agents and compositions and methods utilizing same useful in diagnosing and/or treating or preventing plaque forming diseases 审中-公开用于诊断和/或治疗或预防斑块形成疾病的药物和组合物和方法公开(公告)号：US20050152878A1
公开(公告)日：2005-07-14
申请号：US11073526
申请日：2005-03-08
Applicant: Beka Solomon , Dan Frenkel , Eilat Hanan
Inventor： Beka Solomon , Dan Frenkel , Eilat Hanan
IPC: G01N33/53 , A61K35/74 , A61K35/76 , A61K38/00 , A61K38/17 , A61K39/00 , A61K39/395 , A61K49/00 , A61P19/08 , A61P25/28 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N7/01 , C12N15/02 , A61K48/00 , C12N15/86
CPC classification number: A61K39/0007 , A61K38/1709 , A61K49/0004 , A61K2039/6075 , C07K14/47 , C07K14/4711 , C07K16/18 , C07K2317/622 , C07K2317/74 , C07K2319/00
Abstract: A method of immunizing against plaque forming diseases using display technology is provided. The method utilizes novel agents, or pharmaceutical compositions for vaccination against plaque forming diseases that rely upon presentation of an antigen or epitope on a display vehicle. The method further includes agents, or pharmaceutical compositions for vaccination against plaque forming diseases, which rely upon presentation of an antibody, or an active portion thereof, on a display vehicle. Whether antigens or antibodies are employed, disaggregation of plaques results from the immunization.
Abstract translation: 提供了使用显示技术免疫斑块形成疾病的方法。 该方法利用新型药剂或药物组合物用于接种抗依赖于在显示载体上呈递抗原或表位的斑块形成疾病。 该方法还包括依赖于在显示载体上呈递抗体或其活性部分的针对斑块形成疾病接种的药剂或药物组合物。 无论是使用抗原还是抗体，均免疫后产生斑块分解。
-
3.发明申请Agents and compositions and methods utilizing same useful in diagnosing and/or treating or preventing plaque forming diseases 审中-公开用于诊断和/或治疗或预防斑块形成疾病的药物和组合物和方法公开(公告)号：US20050089510A1
公开(公告)日：2005-04-28
申请号：US10749522
申请日：2004-01-02
Applicant: Beka Solomon , Eilat Hanan , Dan Frenkel
Inventor： Beka Solomon , Eilat Hanan , Dan Frenkel
IPC: G01N33/53 , A61K35/74 , A61K35/76 , A61K38/00 , A61K38/17 , A61K39/00 , A61K39/395 , A61K49/00 , A61P19/08 , A61P25/28 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N7/01 , C12N15/02 , A61K48/00
CPC classification number: A61K39/0007 , A61K38/1709 , A61K49/0004 , A61K2039/6075 , C07K14/47 , C07K14/4711 , C07K16/18 , C07K2317/622 , C07K2317/74 , C07K2319/00
Abstract: A method of immunizing against plaque forming diseases using display technology is provided. The method utilize novel agents, or pharmaceutical compositions for vaccination against plaque forming diseases which rely upon presentation of an antigen or epitope on a display vehicle. The method further includes agents, or pharmaceutical compositions for vaccination against plaque forming diseases, which rely upon presentation of an antibody, or an active portion thereof, on a display vehicle. Whether antigens or antibodies are employed, disaggregation of plaques results from the immunization.
Abstract translation: 提供了使用显示技术免疫斑块形成疾病的方法。 该方法利用依赖于在显示载体上呈递抗原或表位的新型药剂或药物组合物用于接种针对斑块形成疾病的疫苗。 该方法还包括依赖于在显示载体上呈递抗体或其活性部分的针对斑块形成疾病接种的药剂或药物组合物。 无论是使用抗原还是抗体，均免疫后产生斑块分解。
-
公开(公告)号：US06703015B1
公开(公告)日：2004-03-09
申请号：US09473653
申请日：1999-12-29
Applicant: Beka Solomon , Dan Frenkel
Inventor： Beka Solomon , Dan Frenkel
IPC: A01K6300
CPC classification number: C07K14/4711 , A61K38/1709 , A61K39/0007 , A61K2039/6075 , C07K14/47 , C07K16/18 , C07K2317/34 , C07K2317/622 , C07K2319/00
Abstract: A strategy for immunizing against amyloid plaques using display technology. The strategy includes methods, agents, and pharmaceutical compositions for vaccination against plaque forming diseases (e.g. Alzheimer's disease) which rely upon presentation of an antigen or epitope on a display vehicle. The strategy further includes methods, agents, and pharmaceutical compositions for vaccination against plaque forming diseases (e.g. Alzheimer's disease) which rely upon presentation of an antibody, or an active portion thereof, on a display vehicle. Whether antigens or antibodies are employed, desegregation of plaques results from the immunization.
Abstract translation: 使用显示技术免疫淀粉样蛋白斑块的策略。 该策略包括依赖于在显示媒介载体上呈递抗原或表位的针对斑块形成疾病（例如阿尔茨海默病）接种疫苗的方法，药剂和药物组合物。 该策略还包括依赖于在显示载体上呈递抗体或其活性部分的针对斑块形成疾病（例如阿尔茨海默氏病）接种疫苗的方法，药剂和药物组合物。 无论是使用抗原还是抗体，均免疫后产生斑块分解。
-
5.发明申请公开(公告)号：US20080241169A1
公开(公告)日：2008-10-02
申请号：US11927606
申请日：2007-10-29
Applicant: Beka SOLOMON , Dan Frenkel
Inventor： Beka SOLOMON , Dan Frenkel
IPC: A61K39/395 , C07K16/18 , A61K35/76 , G01N33/53 , A61P25/00
CPC classification number: C07K14/4711 , A61K38/1709 , A61K39/0007 , A61K2039/6075 , C07K14/47 , C07K16/18 , C07K2317/34 , C07K2317/622 , C07K2319/00
Abstract: A strategy for immunizing against amyloid plaques using display technology. The strategy includes methods, agents, and pharmaceutical compositions for vaccination against plaque forming diseases (e.g., Alzheimer's disease) that rely upon presentation of an antigen or epitope on a display vehicle. The strategy further includes methods, agents, and pharmaceutical compositions for vaccination against plaque forming diseases (e.g., Alzheimer's disease) that rely upon presentation of an antibody, or an active portion thereof, on a display vehicle. Whether antigens or antibodies are employed, desegregation of plaques results from the immunization.
Abstract translation: 使用显示技术免疫淀粉样蛋白斑块的策略。 该策略包括依赖于在显示媒介载体上呈递抗原或表位的针对斑块形成疾病（例如阿尔茨海默氏病）接种疫苗的方法，药剂和药物组合物。 该策略还包括依赖于在显示媒介载体上呈递抗体或其活性部分的针对斑块形成疾病（例如阿尔茨海默氏病）接种疫苗的方法，药剂和药物组合物。 无论是使用抗原还是抗体，均免疫后产生斑块的分离。
-
Patent Agency Ranking
公开(公告)号：US08691760B2
公开(公告)日：2014-04-08
申请号：US13147406
申请日：2010-02-02
Applicant: Dan Frenkel , Adi Kopelevich , Veronica Lifshitz , Tali Benromano , Nofit Borenstein
Inventor： Dan Frenkel , Adi Kopelevich , Veronica Lifshitz , Tali Benromano , Nofit Borenstein
IPC: A61K38/08 , A61K38/16 , A61K38/05 , A61K38/10 , A61P3/08 , A61P3/10 , A61P9/00 , A61P25/00 , A61P31/12 , C07K14/00 , C07K7/06 , C07K7/08
CPC classification number: A61K38/16
Abstract: Use of an isolated peptide comprising an amino acid sequence being no more than 25 amino acids in length, the amino acid sequence comprising at least one aspartate or a homolog thereof, the peptide having an Insulin-Degrading Enzyme (IDE) inhibitory activity, for the manufacture of a medicament identified for treating a disease selected from the group consisting of diabetes, obesity, hyperglycemia, retinal damage, renal failure, nerve damage, microvascular damage and varicella-zoster virus (VZV) infection is disclosed.
Abstract translation: 使用包含长度不超过25个氨基酸的氨基酸序列的分离肽，所述氨基酸序列包含至少一种天冬氨酸或其同源物，具有胰岛素降解酶（IDE）抑制活性的肽，用于 公开了鉴定用于治疗选自糖尿病，肥胖症，高血糖症，视网膜损伤，肾衰竭，神经损伤，微血管损伤和水痘带状疱疹病毒（VZV）感染的疾病的药物的制备。
-
公开(公告)号：US09757448B2
公开(公告)日：2017-09-12
申请号：US13579817
申请日：2011-02-24
Applicant: Howard Weiner , Dan Frenkel , Veronica Lifshitz
Inventor： Howard Weiner , Dan Frenkel , Veronica Lifshitz
IPC: A61K39/39 , A61K31/739 , A61K38/16 , A61K45/06
CPC classification number: A61K39/39 , A61K31/739 , A61K38/164 , A61K45/06
Abstract: Methods for treating and reducing risk of cerebral amyloid angiopathy (CAA) using nasal vaccination with a proteosome adjuvant.
-
8.发明授权Methods of treating autoimmune diseases of the central nervous system (CNS) and neurodegenerative diseases 有权治疗中枢神经系统（CNS）和神经退行性疾病的自身免疫性疾病的方法公开(公告)号：US08901074B2
公开(公告)日：2014-12-02
申请号：US13813969
申请日：2011-08-04
Applicant: Dan Frenkel , Hilit Levy , Nofit Borenstein , Dorit Farfara , Dorit Trudler
Inventor： Dan Frenkel , Hilit Levy , Nofit Borenstein , Dorit Farfara , Dorit Trudler
CPC classification number: C07K7/06 , A61K38/1709 , A61K47/50 , A61K47/554 , C07K7/08 , C07K14/001 , C07K14/4703
Abstract: An insulin degrading enzyme (IDE) inhibitor for use in the treatment of a disease selected from the group consisting of an autoimmune disease of the central nervous system and a neurodegenerative disease is disclosed.
Abstract translation: 公开了一种用于治疗选自中枢神经系统的自身免疫性疾病和神经变性疾病的疾病的胰岛素降解酶（IDE）抑制剂。
-
公开(公告)号：US20140039581A1
公开(公告)日：2014-02-06
申请号：US14005561
申请日：2012-03-25
Applicant: Uri Oron , Hana Tuby , Dan Frenkel , Dorit Farfara
Inventor： Uri Oron , Hana Tuby , Dan Frenkel , Dorit Farfara
IPC: A61N5/06
CPC classification number: A61N5/0618 , A61N5/0601 , A61N5/0603 , A61N2005/005 , A61N2005/0612 , A61N2005/063 , A61N2005/0645 , A61N2005/0651 , A61N2005/0659 , A61N2005/0662 , A61N2005/067
Abstract: Methods and systems are provided for delivering visible or infrared biostimulatory energy to bone marrow to subjects having or developing Alzheimer's disease. The radiation is delivered to sites remote from the brain at a dose sufficient to cause stimulated mesenchymal stem cells to appear in the brain and degrade β-amyloid. The energy may be coherent light and can be administered transcutaneously, subcutaneously, or via an intramedullary probe.
Abstract translation: 提供的方法和系统用于将可见或红外生物刺激能量递送至具有或发展阿尔茨海默病的受试者的骨髓。 辐射以足以引起刺激的间充质干细胞出现在脑中并降低β-淀粉样蛋白的剂量被输送到远离脑的部位。 能量可以是相干光，并且可以经皮，皮下或经髓内探针施用。
-
公开(公告)号：US20130183245A1
公开(公告)日：2013-07-18
申请号：US13579817
申请日：2011-02-24
Applicant: Howard Weiner , Dan Frenkel , Veronica Lifshitz
Inventor： Howard Weiner , Dan Frenkel , Veronica Lifshitz
CPC classification number: A61K39/39 , A61K31/739 , A61K38/164 , A61K45/06
Abstract: Methods for treating and reducing risk of cerebral amyloid angiopathy (CAA) using nasal vaccination with a proteosome adjuvant.
Abstract translation: 用蛋白质体佐剂鼻腔接种治疗和降低脑淀粉样血管病（CAA）风险的方法。
-
-
-
-
-
-
-
-
-
Search Results
15
records
(took 0.029 seconds)
