摘要:
The invention relates to a medical or dental-medical treatment instrument (1) having a rod-like handpiece (2) with the forward end region of which a tool (3) can be releasably coupled by means of a tool coupling (4), and the rearward end region of which can be releaseably coupled with a connection part (6) by means of a handpiece coupling (5), preferably a plug-in/turn coupling, the handpiece having: a grip sleeve (11) which forms an outer body of the handpiece (2), an oscillatory rod (13) which extends longitudinally in the grip sleeve (11) and is mounted therein radially or also axially elastically yieldingly, an in particular pneumatic oscillation generator (31) for transmitting oscillations to the oscillatory rod (13), and a sleeve (14) surrounding the oscillation generator (31). For reducing noise emissions, the sleeve (14) is of elastically compressible or sound-absorbing material.
摘要:
The invention relates to a medical or dental-medical treatment instrument (1) having a grip sleeve (11), an oscillatory rod (13) which extends longitudinally in the grip sleeve (11) and is mounted therein in a radially or also axially elastically yielding manner, and an oscillation generator (31) for transmitting oscillations to the oscillatory rod (13). In order to attain a compact construction, the oscillatory rod (13) is of a base part and an attachment part which is fixed on the base part.
摘要:
Implementations of the present disclosure provide for determining an encoding type of data. Implementations include receiving a data set from a computer-readable storage medium, decoding the data set using a first encoding type to provide a first plurality of numbers, generating a first distribution based on the first plurality of numbers, decoding the data set using a second encoding type to provide a second plurality of numbers, and generating a second distribution based on the second plurality of numbers. An actual encoding type of the data set is determined based on the first distribution, the second distribution and an expected distribution, and the data set is processed based on the actual encoding type.
摘要:
Implementations of the present disclosure provide for determining an encoding type of data. Implementations include receiving a data set from a computer-readable storage medium, decoding the data set using a first encoding type to provide a first plurality of numbers, generating a first distribution based on the first plurality of numbers, decoding the data set using a second encoding type to provide a second plurality of numbers, and generating a second distribution based on the second plurality of numbers. An actual encoding type of the data set is determined based on the first distribution, the second distribution and an expected distribution, and the data set is processed based on the actual encoding type.
摘要:
The present invention describes methods and processes for the production of proteins, particularly glycoproteins, by animal cell or mammalian cell culture, preferably, but not limited to, fed-batch cell cultures. In one aspect, the methods comprise at least two temperature shifts performed during the culturing period, in which the temperature is lower at the end of the culturing period than at the time of initial cell culture. Throughout their duration, the culturing processes of the invention involving two or more downward shifts in temperature sustain a high viability of the cultured cells, and can yield an increased end titer of protein product, and a high quality of protein product, as determined, e.g., by sialic acid content of the produced protein. In another aspect, the methods comprise the delayed addition of polyanionic compound during the culturing period. The delayed addition of polyanionic compound sustains a high viability of the cultured cells, and can extend the growth phase, delay the onset of the death phase, and arrest the death phase.
摘要:
A cosmetic composition is provided comprising: A) a cosmetically acceptable carrier; and B) 0.05 to 3.0% by weight, based on the weight of the total composition, of a &bgr;-1,3-scleroglucan having a three-dimensional crosslinked triple helix structure and having a mean molecular weight of 1×106 to 12×106.
摘要:
The present invention describes methods and processes for the production of proteins, particularly glycoproteins, by animal cell or mammalian cell culture, illustratively, but not limited to, fed-batch cell cultures. The methods comprise feeding the cells with D-galactose, preferably with feed medium containing D-galactose, preferably daily, to sustain a sialylation effective level of D-galactose in the culture for its duration, thus increasing sialylation of the produced proteins. The methods can also comprise at least two temperature shifts performed during the culturing period, in which the temperature is lower at the end of the culturing period than at the time of initial cell culture. The cell culture processes of the invention involving two or more temperature shifts sustain a high cell viability, and can allow for an extended protein production phase. The methods can also comprise the delayed addition of polyanionic compound at a time after inoculation. Supplementation of the cultures with D-galactose, preferably in a feed medium, to sustain galactose at sialylation effective levels in the cultures until the end of a culture run reverses a decline in sialylation that accompanies culture scale up, and is advantageous for large scale culturing processes.
摘要:
A time zone identifier for a geographic location is generated by receiving a request, including a first information portion in the time zone identifier that represents a time difference between a standard time and a local base time for the geographic location, and, if there exists a rule specifying when the geographic location observes daylight saving time, including a second information portion identifying the rule in the time zone identifier. Otherwise, the second information portion is not included. A computer-readable data structure for a time zone identifier includes a first attribute for the first information portion and a second attribute for the second information portion. A computer system includes a rule repository and a time zone management module.
摘要:
The invention relates to a setting gauge (21) for setting a depth stop (6) on a handpiece (1), which has a connection device (3) for the releasable connection of a pin-shaped tool (4) with the handpiece (1), in particular for setting a depth stop (6) on a handpiece (1) for a working of a root canal (W2) in a tooth (Z). So that the setting of the depth stop can be effected more simply and with little manual effort, the setting gauge (21) has a connection element for connecting and positioning the setting gauge (21) on the handpiece (1) and at least one scale (27a, 27b, 27c) on the setting gauge body (22) which, in the position of the setting gauge (21) connected with the handpiece (1), extends parallel to the depth stop (6) and its setting path.
摘要:
A cosmetic composition is provided comprising:A) a cosmetically acceptable carrier; andB) 0.05 to 3.0 % by weight, based on the weight of the total composition, of a .beta.-1,3-scleroglucan having a three-dimensional crosslinked triple helix structure and having a mean molecular weight of 1.times.10.sup.6 to 12.times.10.sup.6.