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公开(公告)号：US20240268806A1
公开(公告)日：2024-08-15
申请号：US18109646
申请日：2023-02-14
Applicant: Boston Scientific Scimed Inc.
Inventor： Gary John Pederson, JR. , Michael Nagel , Andrew Roiko , Aaron Cooper Foss
IPC: A61B17/00
CPC classification number: A61B17/0057 , A61B2017/00004 , A61B2017/00623 , A61B2017/00632 , A61B2017/00884
Abstract: Systems, devices, and methods for closing a large bore access site are disclosed. An example system may include a delivery catheter and a closure device releasably coupled to the delivery catheter. The closure device may include an expandable frame and a patch secured to the expandable frame. The closure device may be configured to shift between a delivery configuration and an expanded configuration. The closure device may be configured to be delivered by the delivery catheter through a blood vessel to a position adjacent to a large bore opening formed in the blood vessel while in the delivery configuration and then shifted to the expanded configuration within the blood vessel so that the patch engages and covers the large bore opening.
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2.发明公开公开(公告)号：US20240307594A1
公开(公告)日：2024-09-19
申请号：US18606526
申请日：2024-03-15
Applicant: Boston Scientific Scimed, Inc.
Inventor： Jonathan Pascal Chaky , Ryan Lee Reifsteck , Aaron Cooper Foss , Nicholas Michael Job
CPC classification number: A61L31/16 , A61L31/042 , A61L2300/216 , A61L2300/606 , A61L2300/62 , A61L2300/63 , A61L2420/02 , A61L2420/06
Abstract: A medical device may be coated with a therapeutic composition that includes everolimus. Everolimus crystals may be coated with a mixture of excipients to form encapsulated everolimus crystals suspended in a coating composition. The medical device may be contacted with the coating composition in order to form a coating on the medical device. Coating the everolimus crystals with a mixture of excipients to form encapsulated everolimus crystals suspended in a coating composition may include suspending everolimus crystals in a first solution that includes acetyl tri-butyl citrate (ATBC) and adding a second solution to the first solution, the second solution including ethyl cellulose (EC), the EC mixing with the ATBC and coating the everolimus crystals, thereby forming a coating suspension including coated everolimus crystals in the suspension.
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3.发明公开公开(公告)号：US20240342346A1
公开(公告)日：2024-10-17
申请号：US18633245
申请日：2024-04-11
Applicant: Boston Scientific Scimed, Inc.
Inventor： Andrew J. Ro , Nicholas Michael Job , Aaron Cooper Foss , Amanda Maxwell
CPC classification number: A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61M2025/105
Abstract: A medical device may be coated with a therapeutic composition that includes everolimus. Everolimus crystals may be coated with a mixture of excipients to form encapsulated everolimus crystals suspended in a coating composition. An illustrative coating composition may comprise a mixture of excipients including a bioresorbable or thermo-gelling polymer and a plasticizing agent and a therapeutic agent. The bioresorbable or thermo-gelling polymer may be selected from polycaprolactone (PCL) or poloxamer.
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4.发明公开公开(公告)号：US20240342348A1
公开(公告)日：2024-10-17
申请号：US18632758
申请日：2024-04-11
Applicant: Boston Scientific Scimed, Inc.
Inventor： Thomas John Herbst , Edward Kopesky , Steven L. Kangas , Hongxia Zeng , Aaron Cooper Foss
CPC classification number: A61L33/0041 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/204 , A61L2300/216 , A61L2300/416 , A61L2300/42 , A61L2300/61 , A61L2300/622 , A61L2300/802 , A61L2420/02 , A61L2420/08
Abstract: A medical device may be coated with a therapeutic composition that includes a direct oral anticoagulant. An illustrative drug coating composition may comprise an excipient including polylactic acid (PLA), poly(lactic-co-glycolic acid) (PLGA), or poly(vinylidene fluoride)-co-hexafluoropropylene (PVDF-HFP) and a direct oral anticoagulant (DOAC). The illustrative drug coating may be applied to an outer surface of a medical device.
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