公开(公告)号：US08747846B2

公开(公告)日：2014-06-10

申请号：US13470177

申请日：2012-05-11

申请人： Brad J. Spellberg ,  Lin Lin ,  Ashraf Ibrahim ,  Guanpingsheng Luo

发明人： Brad J. Spellberg ,  Lin Lin ,  Ashraf Ibrahim ,  Guanpingsheng Luo

IPC分类号： A61K39/00 ,  A61K39/395

CPC分类号： C07K14/22 ,  A61K39/02 ,  A61K39/104 ,  A61K2039/55505 ,  C07K14/212 ,  C07K16/1203 ,  C07K16/1217 ,  C07K2317/34

摘要： The present invention provides vaccine compositions comprising OmpA, or antigenic fragments thereof, and related methods of active immunization against A. baumannii infection. The invention also provides antibodies and antigen-binding parts thereof that specifically bind to OmpA, and related methods of passive immunization against A. baumannii infection. The compositions and methods of the invention are useful for preventing or treating A. baumannii infections, including those caused by strains resistant to carbapenems and all other antibiotics except colistin or tigecycline, also referred to as extreme drug resistant (XDR) A. baumannii infections, and those resistant to every FDA approved antibiotic, also referred to as pan-drug resistant (PDR) A. baumannii infections.

摘要翻译： 本发明提供包含OmpA或其抗原性片段的疫苗组合物，以及针对鲍曼不动杆菌感染的主动免疫的相关方法。 本发明还提供了特异性结合OmpA的抗体及其抗原结合部分，以及针对鲍氏不动杆菌感染的相关的被动免疫方法。 本发明的组合物和方法可用于预防或治疗鲍曼不动杆菌感染，包括由对碳青霉烯类耐受的菌株和除粘菌素或替加环素之外的所有其它抗生素引起的鲍曼不动杆菌感染，也被称为极耐药（XDR）A.鲍曼不动杆菌感染， 而那些对每一个FDA批准的抗生素都有抗药性，也被称为泛耐药（PDR）A.鲍曼不动杆菌感染。

公开(公告)号：US20130202616A1

公开(公告)日：2013-08-08

申请号：US13749499

申请日：2013-01-24

申请人： Brad J. Spellberg ,  Lin Lin

发明人： Brad J. Spellberg ,  Lin Lin

IPC分类号： C12N9/86 ,  C07K16/40

CPC分类号： C12N9/86 ,  A61K2039/505 ,  C07K16/1203 ,  C07K16/40 ,  C12Y305/02006

摘要： The present invention provides vaccine and pharmaceutical compositions for treating or preventing bacterial inventions. The vaccine compositions of the invention include a carbapenemase such as a serine carbapenemase, a metallo-β-lactamase or an immunogenic fragment thereof. The pharmaceutical compositions include an anti-carbapenemase antibody or fragment thereof. Also provided are methods for treating and preventing a bacterial infection using the vaccine and pharmaceutical compositions of the invention. The invention further provides antibody conjugates that include an antibody or fragment thereof conjugated to a siderophore or an analog thereof.

摘要翻译： 本发明提供用于治疗或预防细菌发明的疫苗和药物组合物。 本发明的疫苗组合物包括碳青霉烯酶如丝氨酸碳青霉烯酶，金属β-内酰胺酶或其免疫原性片段。 药物组合物包括抗碳青霉烯酶抗体或其片段。 还提供了使用本发明的疫苗和药物组合物治疗和预防细菌感染的方法。 本发明还提供了抗体缀合物，其包括与铁载体或其类似物缀合的抗体或其片段。

公开(公告)号：US20120301474A1

公开(公告)日：2012-11-29

申请号：US13470177

申请日：2012-05-11

申请人： Brad J. Spellberg ,  Lin Lin ,  Ashraf Ibrahim ,  Guanpingsheng Luo

发明人： Brad J. Spellberg ,  Lin Lin ,  Ashraf Ibrahim ,  Guanpingsheng Luo

IPC分类号： A61K39/02 ,  C07K7/08 ,  C07K7/06 ,  C07K5/08 ,  A61P37/04 ,  C12N15/63 ,  C07K16/12 ,  A61K39/395 ,  A61P31/04 ,  C07K14/21 ,  C12N15/31

CPC分类号： C07K14/22 ,  A61K39/02 ,  A61K39/104 ,  A61K2039/55505 ,  C07K14/212 ,  C07K16/1203 ,  C07K16/1217 ,  C07K2317/34

摘要： The present invention provides vaccine compositions comprising OmpA, or antigenic fragments thereof, and related methods of active immunization against A. baumannii infection. The invention also provides antibodies and antigen-binding parts thereof that specifically bind to OmpA, and related methods of passive immunization against A. baumannii infection. The compositions and methods of the invention are useful for preventing or treating A. baumannii infections, including those caused by strains resistant to carbapenems and all other antibiotics except colistin or tigecycline, also referred to as extreme drug resistant (XDR) A. baumannii infections, and those resistant to every FDA approved antibiotic, also referred to as pan-drug resistant (PDR) A. baumannii infections.

摘要翻译： 本发明提供包含OmpA或其抗原性片段的疫苗组合物，以及针对鲍曼不动杆菌感染的主动免疫的相关方法。 本发明还提供了特异性结合OmpA的抗体及其抗原结合部分，以及针对鲍氏不动杆菌感染的相关的被动免疫方法。 本发明的组合物和方法可用于预防或治疗鲍曼不动杆菌感染，包括由对碳青霉烯类耐受的菌株和除粘菌素或替加环素之外的所有其它抗生素引起的鲍曼不动杆菌感染，也被称为极耐药（XDR）A.鲍曼不动杆菌感染， 而那些对每一个FDA批准的抗生素都有抗药性，也被称为泛耐药（PDR）A.鲍曼不动杆菌感染。

公开(公告)号：US08909718B2

公开(公告)日：2014-12-09

申请号：US13172098

申请日：2011-06-29

申请人： Lin Lin ,  Ping Lin

发明人： Lin Lin ,  Ping Lin

IPC分类号： G06F15/16 ,  H04L12/64

CPC分类号： H04L12/6418

摘要： A method and apparatus for incorporating a third user into an instant message (IM) session. In one embodiment, an IM server receives a first IM from a first user directed toward a second user. The IM server makes a determination that the second user is not available to respond to the first IM. In response to the determination, the IM server identifies a third user to whom the first IM is to be forwarded, and automatically forwards the first IM to the third user. In another embodiment, the IM server receives a transfer request from the second user to transfer the IM session from the second user to the third user. The IM server automatically determines a subset portion of a plurality of IMs communicated between the first user and the second user, and provides the transfer request and the subset portion to the third user.

摘要翻译： 一种用于将第三用户并入即时消息（IM）会话的方法和装置。 在一个实施例中，IM服务器从第一用户接收指向第二用户的第一IM。 IM服务器确定第二用户无法响应第一个IM。 响应于该确定，IM服务器识别要向其转发第一IM的第三用户，并自动将第一IM转发给第三用户。 在另一个实施例中，IM服务器从第二用户接收传送请求，以将IM会话从第二用户传送到第三用户。 IM服务器自动确定在第一用户和第二用户之间传送的多个IM的子集部分，并且向第三用户提供传送请求和子集部分。

公开(公告)号：US08558822B2

公开(公告)日：2013-10-15

申请号：US12717413

申请日：2010-03-04

申请人： Lin Lin ,  Wen-Hung Wang ,  Shyh-Jeng Chen

发明人： Lin Lin ,  Wen-Hung Wang ,  Shyh-Jeng Chen

IPC分类号： G06F3/038

CPC分类号： G09G3/3655 ,  G02F1/136204 ,  G09G2300/0426 ,  G09G2330/04 ,  H01L23/60 ,  H01L27/0251 ,  H01L2924/0002 ,  H01L2924/00

摘要： A liquid crystal display includes an array substrate, a color filter substrate facing the array substrate, and a liquid crystal layer provided between the array substrate and the color filter substrate. The array substrate includes a driving device, at least one conductive wiring, and a transient voltage suppressor. The driving device includes a driver. The driver has at least one common voltage terminal. The conductive wiring has a connection point and is coupled to the common voltage terminal of the driver. The transient voltage suppressor is coupled to a ground terminal and the connection point, and the connection point is near the common voltage terminal.

摘要翻译： 液晶显示器包括阵列基板，面向阵列基板的滤色器基板和设置在阵列基板和滤色器基板之间的液晶层。 阵列基板包括驱动装置，至少一个导电布线和瞬态电压抑制器。 驱动装置包括驱动器。 驱动器至少有一个公共电压端子。 导电布线具有连接点并耦合到驱动器的公共电压端子。 瞬态电压抑制器耦合到接地端子和连接点，连接点靠近公共电压端子。

公开(公告)号：US08339437B2

公开(公告)日：2012-12-25

申请号：US11837005

申请日：2007-08-10

申请人： Lin Lin ,  Xiaojun Mo ,  Yanyu Wu ,  Yu Su

发明人： Lin Lin ,  Xiaojun Mo ,  Yanyu Wu ,  Yu Su

IPC分类号： H04N7/14 ,  H04M1/00

CPC分类号： H04N7/15 ,  H04N7/17336 ,  H04N21/2385 ,  H04N21/2393 ,  H04N21/41407 ,  H04N21/4788 ,  H04N21/6131

摘要： The present invention discloses a video communication method and system, wherein, during an audio conversation between a calling party and a called party, an IMRS (Integrated Media Resource Server) plays a video to the calling party or the called party; or when a calling party initiates a video phone call request to a called party which does not support video phone call, an audio channel is established between the calling party and the called party and a video channel is established between the calling party and an IMRS, and when an audio conversation is established between the calling party and the called party, the IMRS plays video to the calling party; or when an audio conversation and a video conversation are established between a calling party and a called party, one party replaces its video with that played to the other party by the IMRS, therefore capabilities of developing new communication services are improved.

摘要翻译： 本发明公开了一种视频通信方法和系统，其中，在主叫方和被叫方之间的音频对话期间，IMRS（集成媒体资源服务器）向主叫方或被叫方播放视频; 或者当主叫方向不支持视频电话呼叫的被叫方发起视频电话呼叫请求时，在呼叫方和被叫方之间建立音频信道，并且在呼叫方与IMRS之间建立视频信道， 并且当主叫方和被叫方之间建立音频对话时，IMRS向主叫方播放视频; 或者当在主叫方和被叫方之间建立音频对话和视频对话时，一方通过IMRS替换其播放的对方的视频，从而提高开发新的通信服务的能力。

公开(公告)号：US08204473B2

公开(公告)日：2012-06-19

申请号：US12642128

申请日：2009-12-18

申请人： James E. Mathis ,  Lin Lin

发明人： James E. Mathis ,  Lin Lin

IPC分类号： H04M11/04

CPC分类号： G08B27/001

摘要： An information distribution device performs a method for selectively distributing media associated with an incident to a plurality of responders assigned to the incident. The method includes receiving, at the information distribution device, an incident information bundle comprising media inputs associated with the incident. For each responder in the plurality of responders assigned to the incident, the information distribution device: determines a set of roles for the responder; selects a set of filtering templates designed based on the set of roles; applies the set of filtering templates to the information bundle to generate a responder information bundle that includes a subset of the media inputs that is customized to the set of roles for the responder; and delivers the responder information bundle to the responder.

摘要翻译： 信息分配装置执行用于选择性地将与事件相关联的媒体分发给分配给事件的多个响应者的方法。 该方法包括在信息分发设备处接收包括与事件相关联的媒体输入的事件信息束。 对于分配给事件的多个响应者中的每个响应者，信息分发设备：确定响应者的一组角色; 选择一组基于角色集合设计的过滤模板; 将一组过滤模板应用于信息包以生成响应者信息包，其包括针对响应者的一组角色定制的媒体输入的子集; 并将响应者信息包传递给响应者。

公开(公告)号：US08020672B2

公开(公告)日：2011-09-20

申请号：US12087217

申请日：2006-01-12

申请人： Lin Lin ,  Ziyou Xiong ,  Alan Matthew Finn ,  Pei-Yuan Peng ,  Pengju Kang ,  Mauro J. Atalla ,  Meghna Misra ,  Christian Maria Netter

发明人： Lin Lin ,  Ziyou Xiong ,  Alan Matthew Finn ,  Pei-Yuan Peng ,  Pengju Kang ,  Mauro J. Atalla ,  Meghna Misra ,  Christian Maria Netter

IPC分类号： B66B1/34

CPC分类号： B66B1/34

摘要： An elevator control system (24) provides elevator dispatch and door control based on passenger data received from a video monitoring system. The video monitoring system includes a video processor (16) connected to receive video input from at least one video camera (12). The video processor (16) tracks objects located within the field of view of the video camera, and calculates passenger data parameters associated with each tracked object. The elevator controller (24) provides elevator dispatch (26), door control (28), and security functions (30) based in part on passenger data provided by the video processor (16). The security functions may also be based in part on data from access control systems (14).

摘要翻译： 电梯控制系统（24）基于从视频监控系统接收的乘客数据提供电梯调度和门控制。 该视频监控系统包括连接到接收来自至少一个摄像机（12）的视频输入的视频处理器（16）。 视频处理器（16）跟踪位于视频摄像机视场内的对象，并且计算与每个跟踪对象相关联的乘客数据参数。 部分由视频处理器（16）提供的乘客数据，电梯控制器（24）提供电梯调度（26），门控制（28）和安全功能（30）。 安全功能还可以部分地基于来自访问控制系统（14）的数据。

公开(公告)号：US07952474B2

公开(公告)日：2011-05-31

申请号：US11885814

申请日：2005-03-15

申请人： Pengju Kang ,  Alan M. Finn ,  Robert N. Tomastik ,  Thomas M. Gillis ,  Ziyou Xiong ,  Lin Lin ,  Pei-Yuan Peng

发明人： Pengju Kang ,  Alan M. Finn ,  Robert N. Tomastik ,  Thomas M. Gillis ,  Ziyou Xiong ,  Lin Lin ,  Pei-Yuan Peng

IPC分类号： G08B19/00

CPC分类号： G08B29/183 ,  G08B13/19697 ,  G08B29/186

摘要： An alarm filter (22) for use in a security system (14) to reduce the occurrence of nuisance alarms receives sensor signals (S1-Sn, Sv) from a plurality of sensors (18, 20) included in the security system (14). The alarm filter (22) produces an opinion output as a function of the sensor signals and selectively modifies the sensor signals as a function of the opinion output to produce verified sensor signals (S1′-Sn′).

摘要翻译： 用于安全系统（14）中用于减少妨扰报警的发生的报警过滤器（22）从包括在安全系统（14）中的多个传感器（18,20）接收传感器信号（S1-Sn，Sv） 。 报警过滤器（22）产生作为传感器信号的函数的意见输出，并根据意见输出选择性地修改传感器信号以产生经验证的传感器信号（S1'-Sn'）。

公开(公告)号：US20090303310A1

公开(公告)日：2009-12-10

申请号：US12538591

申请日：2009-08-10

申请人： Hong Zhang ,  Gaofeng Yang ,  Lin Lin

发明人： Hong Zhang ,  Gaofeng Yang ,  Lin Lin

IPC分类号： H04N7/14

CPC分类号： H04N7/141 ,  H04L65/104 ,  H04L65/1069 ,  H04L69/24 ,  H04M3/42017

摘要： A video interworking gateway device, a system and method for implementing a video phone call service are provided, which processes the service when a call object changes if the call is not disconnected. The system includes a video interworking gateway device, a broadband resource device and a bearer connection device. The video interworking gateway device negotiates with a calling H.324 entity about parameters, and connects the calling H.324 entity to the broadband resource device on obtaining negotiation parameters of the calling H.324 entity; the video interworking gateway device negotiates with a called H.324 entity about parameters, obtains negotiation parameters of the called H.324 entity, exchanges the negotiation parameters of the calling H.324 entity and those of the called H.324 entity between the calling H.324 entity and the called H.324 entity, and disconnects the connection between the calling H.324 entity and the broadband resource device.

摘要翻译： 提供了视频互通网关设备，用于实现视频电话呼叫服务的系统和方法，当呼叫没有断开时，当呼叫对象改变时处理该服务。 该系统包括视频互通网关设备，宽带资源设备和承载连接设备。 视频互通网关设备与呼叫H.324实体协商参数，并通过获取呼叫H.324实体的协商参数将呼叫H.324实体连接到宽带资源设备; 视频互通网关设备与被叫H.324实体协商关于参数，获取被叫H.324实体的协商参数，在呼叫之间交换呼叫H.324实体和被叫H.324实体的协商参数 H.324实体和被叫H.324实体，并断开呼叫H.324实体与宽带资源设备之间的连接。