公开(公告)号：US09104575B2

公开(公告)日：2015-08-11

申请号：US13589128

申请日：2012-08-18

申请人： Bret Wayne Holley ,  Ashwani Kumar ,  Tiep Quoc Pham

发明人： Bret Wayne Holley ,  Ashwani Kumar ,  Tiep Quoc Pham

IPC分类号： G06F11/07 ,  G06F11/20

CPC分类号： G06F11/0793 ,  G06F11/0724 ,  G06F11/076 ,  G06F11/0766 ,  G06F11/2005 ,  G06F11/2007 ,  G06F11/2092

摘要： A method for recovering from an error in a multi-core storage-system component is disclosed. In one embodiment, such a method includes detecting an error in a first core of a multi-core component. The method determines whether the error was one of (1) detected by the first core; and (2) detected by a core other than the first core. In the event the error was detected by the first core and the error is recoverable, the first core recovers from the error without substantially impacting operation of other cores in the multi-core component. In the event the error was detected by a core other than the first core and the error is recoverable, a core other than the first core recovers from the error without substantially impacting operation of other cores in the multi-core component. A corresponding apparatus and computer program product are also disclosed.

摘要翻译： 公开了一种用于从多核存储系统组件中的错误中恢复的方法。 在一个实施例中，这种方法包括检测多核分量的第一核心中的错误。 该方法确定误差是否由第一核心检测到的（1）之一; 和（2）由除第一芯之外的芯检测。 在第一个核心检测到错误并且可以恢复错误的情况下，第一个核心从错误中恢复，而不会显着影响多核心组件中其他核心的操作。 在由第一核心以外的核心检测到错误并且可恢复错误的情况下，除了第一核心之外的核心从错误中恢复，而不会在多核心组件中实质上影响其他核心的操作。 还公开了相应的装置和计算机程序产品。

公开(公告)号：US20100239691A1

公开(公告)日：2010-09-23

申请号：US12666008

申请日：2008-06-20

申请人： Adrie J.C. Steyn ,  Ashwani Kumar

发明人： Adrie J.C. Steyn ,  Ashwani Kumar

IPC分类号： A61K33/00 ,  G01N33/573 ,  A61K38/19

CPC分类号： G01N33/5695 ,  G01N2333/91205 ,  G01N2500/04

摘要： Methods for screening for agents that modulate the activation state, i.e., active growth or persistence, of Mycobacterium tuberculosis (Mtb), methods of treating an Mtb infection in a subject using agents identified by the screening methods, and methods for screening for a latent Mtb infection in a subject are disclosed. The screening methods involve contacting a Mtb sensor kinase with an agent to be tested, then detecting the response of the Mtb sensor kinase to modulating ligands or detecting changes in the oxidation state of the heme iron of the Mtb sensor kinase. The methods for treating an Mtb infection in a subject involve administering a therapeutically effective amount of an agent identified by the screening methods. The methods for screening for a latent Mtb infection in a subject involve detecting carbon monoxide or nitric oxide binding to heme iron of Mtb sensor kinases.

摘要翻译： 用于筛选调节结核分枝杆菌（Mtb）的活化状态，即活性生长或持久性的试剂的方法，使用通过筛选方法鉴定的试剂处理受试者中的Mtb感染的方法，以及用于筛选潜伏性Mtb 披露了受试者的感染。 筛选方法包括将Mtb传感器激酶与待测试的试剂接触，然后检测Mtb传感器激酶对调节配体的反应或检测Mtb传感器激酶的血红素铁的氧化状态的变化。 用于治疗受试者的Mtb感染的方法包括施用治疗有效量的通过筛选方法鉴定的药剂。 用于筛选受试者潜伏性Mtb感染的方法涉及检测一氧化碳或一氧化氮与Mtb传感器激酶的血红素结合。

公开(公告)号：US20100007676A1

公开(公告)日：2010-01-14

申请号：US12172530

申请日：2008-07-14

申请人： Ashwani Kumar ,  Adrian Fraser ,  Philip O. Williams

发明人： Ashwani Kumar ,  Adrian Fraser ,  Philip O. Williams

IPC分类号： G09G5/00 ,  G06T17/40

CPC分类号： G06T19/20 ,  G06T2219/2004 ,  G06T2219/2008

摘要： A system, method, and computer program for component scattering, comprising calculating a bounding box for each of a plurality of parts; calculating a centroid corresponding to each of said bounding boxes; placing a first part having a bounding box and a centroid at said start position, and; placing said plurality of parts in a pre-determined direction from said first part; whereby in a single operation said plurality of parts are logically added to an assembly view in a pre-determined manner, and appropriate means and computer-readable instructions.

摘要翻译： 一种用于分量散射的系统，方法和计算机程序，包括计算多个部分中的每一个的边界框; 计算对应于每个所述边界框的质心; 在所述起始位置放置具有边界框和质心的第一部分; 将所述多个部件从所述第一部件放置在预定方向上; 由此在单个操作中，所述多个部件以预定方式逻辑地添加到组装视图，以及适当的装置和计算机可读指令。

公开(公告)号：US07496784B1

公开(公告)日：2009-02-24

申请号：US11971911

申请日：2008-01-10

申请人： Beth Ann Peterson ,  Todd C. Sorenson ,  Matthew Joseph Kalos ,  Ashwani Kumar ,  James Lamar Hood

发明人： Beth Ann Peterson ,  Todd C. Sorenson ,  Matthew Joseph Kalos ,  Ashwani Kumar ,  James Lamar Hood

IPC分类号： G06F11/00

CPC分类号： G06F11/0793 ,  G06F11/0727 ,  G06F11/10

摘要： A method is provided to protect against ill-behaved microcode by balancing between an actual occurrence of a hardware problem and a microcode bug setting a flag appearing as a hardware problem. In this method, the error recovery is performed only on a single piece of hardware and no further error recovery action is taken on other pieces of similar hardware. The approach addresses the problem by treating a hit on one card as a hardware problem, but as a bug on subsequent cards. The invention keeps track of whether or not the same event has occurred on the same type of hardware so not to take action on more than one instance of the hardware. Subsequent hits on another instance of the hardware will not trigger the hardware related recovery on additional hardware.

摘要翻译： 提供了一种通过平衡实际发生的硬件问题和设置出现为硬件问题的标志的微代码错误来防止不良行为微代码的方法。 在该方法中，仅在单个硬件上执行错误恢复，并且不对其他类似硬件进行进一步的错误恢复操作。 该方法通过将一张卡上的打击视为硬件问题来解决问题，但是作为后续卡上的错误。 本发明跟踪相同类型的硬件上是否发生了相同的事件，所以不对多个硬件实例采取行动。 在另一个硬件实例上的后续命中不会触发额外硬件上的硬件相关恢复。

公开(公告)号：US20140053019A1

公开(公告)日：2014-02-20

申请号：US13589128

申请日：2012-08-18

申请人： Bret W. Holley ,  Ashwani Kumar ,  Tiep Q. Pham

发明人： Bret W. Holley ,  Ashwani Kumar ,  Tiep Q. Pham

IPC分类号： G06F11/16

CPC分类号： G06F11/0793 ,  G06F11/0724 ,  G06F11/076 ,  G06F11/0766 ,  G06F11/2005 ,  G06F11/2007 ,  G06F11/2092

摘要： A method for recovering from an error in a multi-core storage-system component is disclosed. In one embodiment, such a method includes detecting an error in a first core of a multi-core component. The method determines whether the error was one of (1) detected by the first core; and (2) detected by a core other than the first core. In the event the error was detected by the first core and the error is recoverable, the first core recovers from the error without substantially impacting operation of other cores in the multi-core component. In the event the error was detected by a core other than the first core and the error is recoverable, a core other than the first core recovers from the error without substantially impacting operation of other cores in the multi-core component. A corresponding apparatus and computer program product are also disclosed.

摘要翻译： 公开了一种用于从多核存储系统组件中的错误中恢复的方法。 在一个实施例中，这种方法包括检测多核分量的第一核心中的错误。 该方法确定误差是否由第一核心检测到的（1）之一; 和（2）由除第一芯之外的芯检测。 在第一个核心检测到错误并且可以恢复错误的情况下，第一个核心从错误中恢复，而不会显着影响多核心组件中其他核心的操作。 在由第一核心以外的核心检测到错误并且可恢复错误的情况下，除了第一核心之外的核心从错误中恢复，而不会在多核心组件中实质上影响其他核心的操作。 还公开了相应的装置和计算机程序产品。

公开(公告)号：US08274509B2

公开(公告)日：2012-09-25

申请号：US12172530

申请日：2008-07-14

申请人： Ashwani Kumar ,  Adrian Fraser ,  Philip O. Williams

发明人： Ashwani Kumar ,  Adrian Fraser ,  Philip O. Williams

IPC分类号： G06T17/00

CPC分类号： G06T19/20 ,  G06T2219/2004 ,  G06T2219/2008

摘要： A system, method, and computer program for component scattering, comprising calculating a bounding box for each of a plurality of parts; calculating a centroid corresponding to each of said bounding boxes; placing a first part having a bounding box and a centroid at said start position, and; placing said plurality of parts in a pre-determined direction from said first part; whereby in a single operation said plurality of parts are logically added to an assembly view in a pre-determined manner, and appropriate means and computer-readable instructions.

摘要翻译： 一种用于分量散射的系统，方法和计算机程序，包括计算多个部分中的每一个的边界框; 计算对应于每个所述边界框的质心; 在所述起始位置放置具有边界框和质心的第一部分，以及; 将所述多个部件从所述第一部件放置在预定方向上; 由此在单个操作中，所述多个部件以预定方式逻辑地添加到组装视图，以及适当的装置和计算机可读指令。

公开(公告)号：US07785397B2

公开(公告)日：2010-08-31

申请号：US11885873

申请日：2006-03-10

申请人： Ashwani Kumar ,  Jamal Kurdi

发明人： Ashwani Kumar ,  Jamal Kurdi

IPC分类号： B01D53/22 ,  B01D71/06

CPC分类号： C08L79/08 ,  B01D53/228 ,  B01D67/0006 ,  B01D67/0009 ,  B01D67/0011 ,  B01D69/141 ,  B01D71/64 ,  B01D71/68 ,  B01D2257/504 ,  B01D2323/08 ,  B01D2323/12 ,  B01D2323/22 ,  B01D2323/40 ,  B01D2325/022 ,  B01D2325/20 ,  C08F283/00 ,  C08F283/04 ,  C08J3/246 ,  Y02C10/10 ,  Y02P20/152

摘要： In order to synthesize semi-interpenetrating polymer networks (semi-IPNs) with molecular sieve characteristics, polyetherimide/bismaleimide (PEI/BMI) chromophore composites were made through sol-gel technique. A tunable and compatible chemical structure with fine morphology was obtained through in situ controlled sol-gel polymerization, crosslinking, chemical modification and membrane fabrication. The novel semi-IPN, synthesized and assembled by using ethanol as polar protic modifier and pore former, had a superior structure and morphology suitable for making gas separation membranes. These semi-IPN membranes gave fifteen times higher gas flux without significant decrease in their gas permselectivity than membranes prepared from pure PEL The chemical structures of these novel semi-IPNs were characterized by using FTIR, XPS and SEM. It was discovered for the first time that in situ simultaneous ethoxylation, anionic polymerization of BMI and imide modifications were responsible for creating the new chemical structure and molecular morphology that was different from traditional BMI resins. In addition to the superior structure, this chemical processes have the advantages of using simple green chemistry, ambient temperature and does not require initiators for polymerization.

摘要翻译： 为了合成具有分子筛特性的半互穿聚合物网络（半IPN），通过溶胶 - 凝胶技术制备了聚醚酰亚胺/双马来酰亚胺（PEI / BMI）发色团复合材料。 通过原位控制的溶胶 - 凝胶聚合，交联，化学改性和膜制备，获得具有精细形态的可调谐和相容的化学结构。 通过乙醇作为极性质子改性剂和成孔剂合成和组装的新型半IPN具有优异的结构和形态，适用于制备气体分离膜。 这些半IPN膜比纯PEL制备的膜具有十五倍高的气体通量，而不会显着降低其气体选择性。这些新型半IPN的化学结构通过使用FTIR，XPS和SEM进行表征。 首次发现原位同时乙氧基化，BMI和酰亚胺修饰的阴离子聚合负责产生与传统BMI树脂不同的新化学结构和分子形态。 除了优异的结构外，该化学方法具有使用简单的绿色化学，环境温度并且不需要引发剂进行聚合的优点。

公开(公告)号：US06913772B2

公开(公告)日：2005-07-05

申请号：US10735437

申请日：2003-12-11

申请人： Ghulam Nabi Qazi ,  Bupinder Singh Jaggi ,  Bal Krishan Chandan ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Rakesh Maurya ,  Lila Ram Manhas ,  Ashwani Kumar ,  Bal Krishan Kapahi

发明人： Ghulam Nabi Qazi ,  Bupinder Singh Jaggi ,  Bal Krishan Chandan ,  Krishan Avtar Suri ,  Naresh Kumar Satti ,  Rakesh Maurya ,  Lila Ram Manhas ,  Ashwani Kumar ,  Bal Krishan Kapahi

IPC分类号： A01N25/00 ,  A01N27/00 ,  A01N65/00 ,  A61K31/4745 ,  A61K31/70 ,  A61K36/27 ,  A61K35/78

CPC分类号： A61K36/27 ,  Y10S514/885 ,  Y10S514/893 ,  Y10S514/894

摘要： The present invention relates to a composition useful for hepatoprotection, said composition comprising polar extract of plant Cryptolepis Buchanani and/or fractions of the said extract, and optionally pharmaceutically acceptable additives and a method of producing said composition and also a method of treating a subject using said composition.

摘要翻译： 本发明涉及一种可用于肝保护的组合物，所述组合物包含植物Cryptolepis Buchanani的极性提取物和/或所述提取物的级分，和任选的药学上可接受的添加剂和制备所述组合物的方法，以及使用 所说的组合。

公开(公告)号：US08795978B2

公开(公告)日：2014-08-05

申请号：US12666008

申请日：2008-06-20

申请人： Adrie J. C. Steyn ,  Ashwani Kumar

发明人： Adrie J. C. Steyn ,  Ashwani Kumar

IPC分类号： C12Q1/48 ,  C12Q1/02

CPC分类号： G01N33/5695 ,  G01N2333/91205 ,  G01N2500/04

摘要： Methods for screening for agents that modulate the activation state, i.e., active growth or persistence, of Mycobacterium tuberculosis (Mtb), methods of treating an Mtb infection in a subject using agents identified by the screening methods, and methods for screening for a latent Mtb infection in a subject are disclosed. The screening methods involve contacting a Mtb sensor kinase with an agent to be tested, then detecting the response of the Mtb sensor kinase to modulating ligands or detecting changes in the oxidation state of the heme iron of the Mtb sensor kinase. The methods for treating an Mtb infection in a subject involve administering a therapeutically effective amount of an agent identified by the screening methods. The methods for screening for a latent Mtb infection in a subject involve detecting carbon monoxide or nitric oxide binding to heme iron of Mtb sensor kinases.

摘要翻译： 用于筛选调节结核分枝杆菌（Mtb）的活化状态，即活性生长或持久性的试剂的方法，使用通过筛选方法鉴定的试剂处理受试者中的Mtb感染的方法，以及用于筛选潜伏性Mtb 披露了受试者的感染。 筛选方法包括将Mtb传感器激酶与待测试的试剂接触，然后检测Mtb传感器激酶对调节配体的反应或检测Mtb传感器激酶的血红素铁的氧化状态的变化。 用于治疗受试者的Mtb感染的方法包括施用治疗有效量的通过筛选方法鉴定的药剂。 用于筛选受试者潜伏性Mtb感染的方法涉及检测一氧化碳或一氧化氮与Mtb传感器激酶的血红素结合。

公开(公告)号：US20140172955A1

公开(公告)日：2014-06-19

申请号：US13717647

申请日：2012-12-17

申请人： ULLAS HOLLA P K ,  Ashwani Kumar ,  Pradeep Kumar Warrier

发明人： ULLAS HOLLA P K ,  Ashwani Kumar ,  Pradeep Kumar Warrier

IPC分类号： H04L29/08

CPC分类号： H04L67/10 ,  G06F8/60 ,  G06F9/50 ,  G06F9/5055 ,  H04L67/34

摘要： Various embodiments of systems and methods for distributed mobile enterprise application platform (MEAP) are described herein. In one aspect, the method includes receiving a request to be executed from a mobile device. Based upon the request, one or more middleware components capable of executing the request are determined from one or more remotely located servers. A middleware component from the one or more middleware components is selected for executing the request. The request is sent to the selected middleware component for execution. Based upon the execution, an output is received from the selected middleware component. In one embodiment, the output is stored in a backend system or sent to a portable device from which the request is received. In another embodiment, the output is sent to another middleware component for further execution.

摘要翻译： 本文描述了分布式移动企业应用平台（MEAP）的系统和方法的各种实施例。 一方面，该方法包括从移动设备接收要执行的请求。 基于该请求，从一个或多个远程定位的服务器确定能够执行请求的一个或多个中间件组件。 选择来自一个或多个中间件组件的中间件组件来执行请求。 该请求被发送到所选择的中间件组件以供执行。 基于执行，从所选择的中间件组件接收输出。 在一个实施例中，输出被存储在后端系统中或者被发送到从其接收到该请求的便携式设备。 在另一个实施例中，将输出发送到另一个中间件组件以进一步执行。