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1.
公开(公告)号:US20050089986A1
公开(公告)日:2005-04-28
申请号:US10651967
申请日:2003-09-02
CPC分类号: C12N9/1223 , C12P13/08
摘要: The present invention provides nucleotide sequences from Coryneform bacteria which code for the MtrA and/or MtrB proteins and processes for the fermentative preparation of amino acids using bacteria in which the mtrA and/or mtrB genes are attenuated.
摘要翻译: 本发明提供了编码MtrA和/或MtrB蛋白质的棒状细菌的核苷酸序列,以及使用其中mtrA和/或mtrB基因减毒的细菌发酵制备氨基酸的方法。
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2.
公开(公告)号:US06703223B2
公开(公告)日:2004-03-09
申请号:US09990337
申请日:2001-11-23
IPC分类号: C12P2106
CPC分类号: C12N9/1223 , C12P13/08
摘要: The present invention provides nucleotide sequences from Coryneform bacteria which code for the MtrA and/or MtrB proteins and processes for the fermentative preparation of amino acids using bacteria in which the mtrA and/or mtrB genes are attenuated.
摘要翻译: 本发明提供了编码MtrA和/或MtrB蛋白质的棒状细菌的核苷酸序列,以及使用其中mtrA和/或mtrB基因减毒的细菌发酵制备氨基酸的方法。
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3.
公开(公告)号:US07229802B2
公开(公告)日:2007-06-12
申请号:US10651967
申请日:2003-09-02
CPC分类号: C12N9/1223 , C12P13/08
摘要: The present invention provides nucleotide sequences from Coryneform bacteria which code for the MtrA and/or MtrB proteins and processes for the fermentative preparation of amino acids using bacteria in which the mtrA and/or mtrB genes are attenuated.
摘要翻译: 本发明提供了编码MtrA和/或MtrB蛋白质的棒状细菌的核苷酸序列,以及使用其中mtrA和/或mtrB基因减毒的细菌发酵制备氨基酸的方法。
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公开(公告)号:US07229791B2
公开(公告)日:2007-06-12
申请号:US10411318
申请日:2003-04-11
CPC分类号: C12N9/1223 , C12P13/08
摘要: The present invention provides nucleotide sequences from Coryneform bacteria which code for the MtrA and/or MtrB proteins and processes for the fermentative preparation of amino acids using bacteria in which the mtrA and/or mtrB genes are attenuated.
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公开(公告)号:US20100196959A1
公开(公告)日:2010-08-05
申请号:US12696449
申请日:2010-01-29
CPC分类号: C12P13/08 , C12N9/0006 , C12P13/227
摘要: The invention relates to mutants and alleles of the opcA gene of coryneform bacteria, which encode variants of the OpcA subunit of glucose 6-phosphate dehydrogenase (EC: 1.1.1.49), and to processes for preparing amino acids, in particular L-lysine and L-tryptophan, by using bacteria which harbor said alleles.
摘要翻译: 本发明涉及编码葡萄糖-6-磷酸脱氢酶(EC:1.1.1.49)的OpcA亚基变体的棒状杆菌细菌的opcA基因的突变体和等位基因,以及制备氨基酸,特别是L-赖氨酸和 L-色氨酸通过使用含有所述等位基因的细菌。
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公开(公告)号:US07700313B2
公开(公告)日:2010-04-20
申请号:US11383253
申请日:2006-05-15
CPC分类号: C12P13/08 , C12N9/0006 , C12P13/227
摘要: The invention relates to mutants and alleles of the opcA gene of coryneform bacteria, which encode variants of the OpcA subunit of glucose 6-phosphate dehydrogenase (EC: 1.1.1.49), and to processes for preparing amino acids, in particular L-lysine and L-tryptophan, by using bacteria which harbor said alleles.
摘要翻译: 本发明涉及编码葡萄糖-6-磷酸脱氢酶(EC:1.1.1.49)的OpcA亚基变体的棒状杆菌细菌的opcA基因的突变体和等位基因,以及制备氨基酸,特别是L-赖氨酸和 L-色氨酸通过使用含有所述等位基因的细菌。
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公开(公告)号:US08153404B2
公开(公告)日:2012-04-10
申请号:US12458966
申请日:2009-07-28
CPC分类号: C12P13/08 , C07K14/34 , C12P13/227
摘要: The invention relates to mutants and alleles of the zwf gene of coryneform bacteria, which encode variants of the Zwf subunit of glucose 6-phosphate dehydrogenase (EC: 1.1.1.49), and to processes for preparing amino acids, in particular L-lysine and L-tryptophan, by using bacteria which harbor said alleles.
摘要翻译: 本发明涉及编码葡萄糖-6-磷酸脱氢酶(EC:1.1.1.49)的Zwf亚基的变体的棒状细菌的zwf基因的突变体和等位基因,以及制备氨基酸,特别是L-赖氨酸和 L-色氨酸通过使用含有所述等位基因的细菌。
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公开(公告)号:US07563602B2
公开(公告)日:2009-07-21
申请号:US12016728
申请日:2008-01-18
CPC分类号: C12P13/22 , C12N9/0006 , C12P13/08 , C12P13/227
摘要: The invention relates to mutants and alleles of the gnd gene from coryneform bacteria coding for 6-phosphogluconate dehydrogenases which contain at position 329 or a comparable position of the amino acid sequence any amino acid other than L-valine, and to processes for the production of amino acids, preferably L-lysine and L-tryptophan, by fermentation using bacteria that contain these alleles.
摘要翻译: 本发明涉及编码6-磷酸葡萄糖酸脱氢酶的棒状细菌的gnd基因的突变体和等位基因,其含有第329位或氨基酸序列与L-缬氨酸以外的任何氨基酸的可比较位置,以及用于生产 氨基酸,优选L-赖氨酸和L-色氨酸,通过使用含有这些等位基因的细菌进行发酵。
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公开(公告)号:US20070224666A1
公开(公告)日:2007-09-27
申请号:US11790063
申请日:2007-04-23
CPC分类号: C12P13/08 , C07K14/34 , C12P13/227
摘要: The invention relates to mutants and alleles of the zwf gene of coryneform bacteria, which encode variants of the Zwf subunit of glucose 6-phosphate dehydrogenase (EC: 1.1.1.49), and to processes for preparing amino acids, in particular L-lysine and L-tryptophan, by using bacteria which harbor said alleles.
摘要翻译: 本发明涉及编码葡萄糖-6-磷酸脱氢酶(EC:1.1.1.49)的Zwf亚基变体的棒状细菌的zwf基因的突变体和等位基因,以及制备氨基酸,特别是L-赖氨酸和 L-色氨酸通过使用含有所述等位基因的细菌。
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公开(公告)号:US20060246554A1
公开(公告)日:2006-11-02
申请号:US11227138
申请日:2005-09-16
CPC分类号: C12P13/22 , C12N9/0006 , C12P13/08 , C12P13/227
摘要: The invention relates to mutants and alleles of the gnd gene from coryneform bacteria coding for 6-phosphogluconate dehydrogenases which contain at position 329 or a comparable position of the amino acid sequence any amino acid other than L-valine, and to processes for the production of amino acids, preferably L-lysine and L-tryptophan, by fermentation using bacteria that contain these alleles.
摘要翻译: 本发明涉及编码6-磷酸葡萄糖酸脱氢酶的棒状细菌的gnd基因的突变体和等位基因,其含有第329位或氨基酸序列与L-缬氨酸以外的任何氨基酸的可比较位置,以及用于生产 氨基酸,优选L-赖氨酸和L-色氨酸,通过使用含有这些等位基因的细菌进行发酵。
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